TLR7 ligand prevents allergen-induced airway hyperresponsiveness and eosinophilia in allergic asthma by a MYD88-dependent and MK2-independent pathway

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 290, Issue 5, 2006, Pages

  Moisan, J ^a   Camateros, P ^a   Thuraisingam, T ^a,c   Marion, D ^a   Koohsari, H ^a   Martin, P ^a   Boghdady, M L ^a   Ding, A ^b   Gaestel, M ^c   Guiot, M C ^d   Martin, J G ^a   Radzioch, D ^a,e  

^a MCGILL UNIVERSITY   (Canada)

^b WEILL CORNELL MEDICAL COLLEGE   (United States)

^c HANNOVER MEDICAL SCHOOL   (Germany)

^d MCGILL UNIVERSITY   (Canada)

^e MONTREAL GENERAL HOSPITAL   (Canada)

Author keywords

Asthma; Eosinophils; Inflammation; Lung; Mitogen activated protein kinase activated protein 2; Toll like receptors

Indexed keywords

ALLERGEN; GAMMA INTERFERON; IMIDAZOQUINOLINE DERIVATIVE; IMMUNOGLOBULIN E; INTERLEUKIN 12P70; INTERLEUKIN 13; INTERLEUKIN 4; INTERLEUKIN 5; LIGAND; METHACHOLINE; MITOGEN ACTIVATED PROTEIN KINASE ACTIVATED PROTEIN KINASE 2; MYELOID DIFFERENTIATION FACTOR 88; OVALBUMIN; PROTEIN KINASE; RESIQUIMOD; TOLL LIKE RECEPTOR 7; UNCLASSIFIED DRUG;

AIRWAY; AIRWAY RESISTANCE; ALLERGIC ASTHMA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY BLOOD LEVEL; ARTICLE; CELL INFILTRATION; COMPLIANCE (PHYSICAL); CONTROLLED STUDY; DRUG EFFECT; EOSINOPHIL; EOSINOPHILIA; INFLAMMATORY CELL; LEUKOCYTE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SENSITIZATION; TH1 CELL; TH2 CELL;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; AIRWAY OBSTRUCTION; ALLERGENS; ANIMALS; ASTHMA; DISEASE MODELS, ANIMAL; EOSINOPHILIA; IMIDAZOLES; LIGANDS; MALE; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED A; MICE, INBRED C57BL; MYELOID DIFFERENTIATION FACTOR 88; PROTEIN KINASES; QUINOLINES; TOLL-LIKE RECEPTOR 7;

EID: 33646569666     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00440.2005     Document Type: Article

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