A novel intranasal Protollin™-based measles vaccine induces mucosal and systemic neutralizing antibody responses and cell-mediated immunity in mice

Vaccine

Volumn 23, Issue 11, 2005, Pages 1374-1383

  Chabot, Sophie ^a   Brewer, Angela ^a   Lowell, George ^b   Plante, Martin ^b   Cyr, Sonya ^b   Burt, David S ^b   Ward, Brian J ^a  

^a MONTREAL GENERAL HOSPITAL   (Canada)

^b ID Biomedical Corporation of Quebec   (Canada)

Author keywords

Adjuvants; Antibody; IgA; Interferon gamma; Measles; Mucosal vaccination; Neutralization; Vaccine

Indexed keywords

BACTERIUM LIPOPOLYSACCHARIDE; GAMMA INTERFERON; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G2A; IMMUNOLOGICAL ADJUVANT; MEASLES ANTIBODY; MEASLES VACCINE; NEUTRALIZING ANTIBODY; OUTER MEMBRANE PROTEIN; PROTOLLIN; UNCLASSIFIED DRUG; VIRUS ANTIGEN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIBODY RESPONSE; ARTICLE; CELLULAR IMMUNITY; CONTROLLED STUDY; DOSE RESPONSE; FEMALE; IMMUNE RESPONSE; IMMUNIZATION; IMMUNOGENICITY; MEASLES; MEASLES VIRUS; MOUSE; MUCOSAL IMMUNITY; NEISSERIA MENINGITIDIS; NONHUMAN; PRIORITY JOURNAL; SHIGELLA FLEXNERI; SPLEEN CELL; TH1 CELL; TH2 CELL;

ADJUVANTS, IMMUNOLOGIC; ADMINISTRATION, INTRANASAL; ANIMALS; ANTIBODIES, VIRAL; CYSTEINE ENDOPEPTIDASES; DRUG COMBINATIONS; FEMALE; IMMUNITY, CELLULAR; IMMUNITY, MUCOSAL; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; INTERFERON TYPE II; LEUKOCYTES; LIPOPOLYSACCHARIDES; MEASLES; MEASLES VACCINE; MICE; MICE, INBRED BALB C; NEISSERIA MENINGITIDIS; NEUTRALIZATION TESTS; SHIGELLA FLEXNERI; SPLEEN; T-LYMPHOCYTES, HELPER-INDUCER; VACCINES, SUBUNIT;

EID: 12344323316     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vaccine.2004.09.010     Document Type: Article

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