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Volumn 86, Issue 18, 2012, Pages 10218-10220

CCR5 mutations distinguish N-terminal modifications of RANTES (CCL5) with agonist versus antagonist activity

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE RECEPTOR CCR5; RANTES;

EID: 84866168919     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.00353-12     Document Type: Article
Times cited : (15)

References (17)
  • 1
    • 0030762506 scopus 로고    scopus 로고
    • CC chemokine receptor 5-mediated signaling and HIV-1 co-receptor activity share common structural determinants. Critical residues in the third extracellular loop support HIV-1 fusion
    • Alkhatib G, et al. 1997. CC chemokine receptor 5-mediated signaling and HIV-1 co-receptor activity share common structural determinants. Critical residues in the third extracellular loop support HIV-1 fusion. J. Biol. Chem. 272:19771-19776.
    • (1997) J. Biol. Chem. , vol.272 , pp. 19771-19776
    • Alkhatib, G.1
  • 2
    • 0037799237 scopus 로고    scopus 로고
    • The core domain of chemokines binds CCR5 extracellular domains while their amino terminus interacts with the transmembrane helix bundle
    • Blanpain C, et al. 2003. The core domain of chemokines binds CCR5 extracellular domains while their amino terminus interacts with the transmembrane helix bundle. J. Biol. Chem. 278:5179-5187.
    • (2003) J. Biol. Chem. , vol.278 , pp. 5179-5187
    • Blanpain, C.1
  • 3
    • 56449100427 scopus 로고    scopus 로고
    • Evolution of CCR5 use before and during coreceptor switching
    • Coetzer M, et al. 2008. Evolution of CCR5 use before and during coreceptor switching. J. Virol. 82:11758-11766.
    • (2008) J. Virol. , vol.82 , pp. 11758-11766
    • Coetzer, M.1
  • 4
    • 0028842207 scopus 로고
    • Vpr is required for efficient replication of human immunodeficiency virus type-1 in mononuclear phagocytes
    • Connor RI, Chen BK, Choe S, Landau NR. 1995. Vpr is required for efficient replication of human immunodeficiency virus type-1 in mononuclear phagocytes. Virology 206:935-944.
    • (1995) Virology , vol.206 , pp. 935-944
    • Connor, R.I.1    Chen, B.K.2    Choe, S.3    Landau, N.R.4
  • 5
    • 0034625144 scopus 로고    scopus 로고
    • A binding pocket for a small molecule inhibitor of HIV-1 entry within the transmembrane helices of CCR5
    • Dragic T, et al. 2000. A binding pocket for a small molecule inhibitor of HIV-1 entry within the transmembrane helices of CCR5. Proc. Natl. Acad. Sci. U. S. A. 97:5639-5644.
    • (2000) Proc. Natl. Acad. Sci. U. S. A. , vol.97 , pp. 5639-5644
    • Dragic, T.1
  • 6
    • 56649122050 scopus 로고    scopus 로고
    • Highly potent, fully recombinant anti-HIV chemokines: reengineering a low-cost microbicide
    • Gaertner H, et al. 2008. Highly potent, fully recombinant anti-HIV chemokines: reengineering a low-cost microbicide. Proc. Natl. Acad. Sci. U. S. A. 105:17706-17711.
    • (2008) Proc. Natl. Acad. Sci. U. S. A. , vol.105 , pp. 17706-17711
    • Gaertner, H.1
  • 7
    • 80053025493 scopus 로고    scopus 로고
    • An allosteric model of maraviroc binding to CCR5
    • Garcia-Perez J, et al. 2011. An allosteric model of maraviroc binding to CCR5. J. Biol. Chem. 286:33409-33421.
    • (2011) J. Biol. Chem. , vol.286 , pp. 33409-33421
    • Garcia-Perez, J.1
  • 8
    • 79953147162 scopus 로고    scopus 로고
    • New insights into the mechanisms whereby low molecular weight CCR5 ligands inhibit HIV-1 infection
    • Garcia-Perez J, et al. 2011. New insights into the mechanisms whereby low molecular weight CCR5 ligands inhibit HIV-1 infection. J. Biol. Chem. 286:4978-4990.
    • (2011) J. Biol. Chem. , vol.286 , pp. 4978-4990
    • Garcia-Perez, J.1
  • 9
    • 0030922697 scopus 로고    scopus 로고
    • Molecular uncoupling of C-C chemokine receptor 5-induced chemotaxis and signal transduction from HIV-1 coreceptor activity
    • Gosling J, et al. 1997. Molecular uncoupling of C-C chemokine receptor 5-induced chemotaxis and signal transduction from HIV-1 coreceptor activity. Proc. Natl. Acad. Sci. U. S. A. 94:5061-5066.
    • (1997) Proc. Natl. Acad. Sci. U. S. A. , vol.94 , pp. 5061-5066
    • Gosling, J.1
  • 10
    • 0035918313 scopus 로고    scopus 로고
    • The TXP motif in the second transmembrane helix of CCR5. A structural determinant of chemokine-induced activation
    • Govaerts C, et al. 2001. The TXP motif in the second transmembrane helix of CCR5. A structural determinant of chemokine-induced activation. J. Biol. Chem. 276:13217-13225.
    • (2001) J. Biol. Chem. , vol.276 , pp. 13217-13225
    • Govaerts, C.1
  • 11
    • 0037449732 scopus 로고    scopus 로고
    • Activation of CCR5 by chemokines involves an aromatic cluster between transmembrane helices 2 and 3
    • Govaerts C, et al. 2003. Activation of CCR5 by chemokines involves an aromatic cluster between transmembrane helices 2 and 3. J. Biol. Chem. 278:1892-1903.
    • (2003) J. Biol. Chem. , vol.278 , pp. 1892-1903
    • Govaerts, C.1
  • 12
    • 9344239350 scopus 로고    scopus 로고
    • Medicinal chemistry applied to a synthetic protein: development of highly potent HIV entry inhibitors
    • Hartley O, et al. 2004. Medicinal chemistry applied to a synthetic protein: development of highly potent HIV entry inhibitors. Proc. Natl. Acad. Sci. U. S. A. 101:16460-16465.
    • (2004) Proc. Natl. Acad. Sci. U. S. A. , vol.101 , pp. 16460-16465
    • Hartley, O.1
  • 13
    • 5644247983 scopus 로고    scopus 로고
    • Prevention of vaginal SHIV transmission in rhesus macaques through inhibition of CCR5
    • Lederman MM, et al. 2004. Prevention of vaginal SHIV transmission in rhesus macaques through inhibition of CCR5. Science 306:485-487.
    • (2004) Science , vol.306 , pp. 485-487
    • Lederman, M.M.1
  • 14
    • 33744954776 scopus 로고    scopus 로고
    • Structural and molecular interactions of CCR5 inhibitors with CCR5
    • Maeda K, et al. 2006. Structural and molecular interactions of CCR5 inhibitors with CCR5. J. Biol. Chem. 281:12688-12698.
    • (2006) J. Biol. Chem. , vol.281 , pp. 12688-12698
    • Maeda, K.1
  • 15
    • 33646514864 scopus 로고    scopus 로고
    • Interaction of small molecule inhibitors of HIV-1 entry with CCR5
    • Seibert C, et al. 2006. Interaction of small molecule inhibitors of HIV-1 entry with CCR5. Virology 349:41-54.
    • (2006) Virology , vol.349 , pp. 41-54
    • Seibert, C.1
  • 16
    • 0033022783 scopus 로고    scopus 로고
    • An orphan G protein-coupled receptor, GPR1, acts as a coreceptor to allow replication of human immunodeficiency virus types 1 and 2 in brain-derived cells
    • Shimizu N, et al. 1999. An orphan G protein-coupled receptor, GPR1, acts as a coreceptor to allow replication of human immunodeficiency virus types 1 and 2 in brain-derived cells. J. Virol. 73:5231-5239.
    • (1999) J. Virol. , vol.73 , pp. 5231-5239
    • Shimizu, N.1
  • 17
    • 80054804698 scopus 로고    scopus 로고
    • Allosteric and orthosteric sites in CC chemokine receptor (CCR5), a chimeric receptor approach
    • Thiele S, et al. 2011. Allosteric and orthosteric sites in CC chemokine receptor (CCR5), a chimeric receptor approach. J. Biol. Chem. 286: 37543-37554.
    • (2011) J. Biol. Chem. , vol.286 , pp. 37543-37554
    • Thiele, S.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.