Dietary oxidized n-3 PUFA induce oxidative stress and inflammation: Role of intestinal absorption of 4-HHE and reactivity in intestinal cells

Journal of Lipid Research

Volumn 53, Issue 10, 2012, Pages 2069-2080

  Awada, Manar ^a,b   Soulage, Christophe O ^b   Meynier, Anne ^c   Debard, Cyrille ^a   Plaisancié, Pascale ^a   Benoit, Bérengère ^d   Picard, Grégory ^d   Loizon, Emmanuelle ^d   Chauvin, Marie Agnès ^a   Estienne, Monique ^a   Peretti, Noël ^d   Guichardant, Michel ^b   Lagarde, Michel ^b   Genot, Claude ^c   Michalski, Marie Caroline ^a,b,d  

^a CarMeN   (France)

^b Univ Lyon   (France)

^c INRA   (France)

^d UNIVERSITÉ LYON 1   (France)

Author keywords

4 hydroxy 2 alkenals; Intestine; Lipid peroxidation; Nutrition; Polyunsaturated fatty acids

Indexed keywords

4 HYDROXY 2 ALKENAL; 4 HYDROXY 2 HEXENAL; GLUCOSE REGULATED PROTEIN 78; HYDROPEROXIDE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; MALONALDEHYDE; OMEGA 3 FATTY ACID; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL COUNT; CONTROLLED STUDY; DIET; ENZYME BLOOD LEVEL; FATTY ACID ANALYSIS; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATION; INTESTINE ABSORPTION; INTESTINE CELL; LIPID COMPOSITION; LIPID PEROXIDATION; MALE; MOUSE; NONHUMAN; OXIDATION; OXIDATIVE STRESS; PANETH CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN MODIFICATION; TRIACYLGLYCEROL BLOOD LEVEL;

ALDEHYDES; ANIMALS; BIOLOGICAL MARKERS; CACO-2 CELLS; DIET, HIGH-FAT; FATTY ACIDS, OMEGA-3; GLUTATHIONE PEROXIDASE; HEAT-SHOCK PROTEINS; HUMANS; INFLAMMATION; INTESTINAL ABSORPTION; INTESTINES; LIPID PEROXIDATION; MALE; MICE; MICE, INBRED C57BL; OXIDATION-REDUCTION; OXIDATIVE STRESS;

EID: 84866145371     PISSN: 00222275     EISSN: 15397262     Source Type: Journal    
DOI: 10.1194/jlr.M026179     Document Type: Article

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