메뉴 건너뛰기




Volumn 125, Issue 13, 2012, Pages 3202-3209

Plakoglobin-dependent regulation of keratinocyte apoptosis by Rnd3

Author keywords

Apoptosis; Desmosomes; Plakoglobin; Rho GTPases; Rnd3

Indexed keywords

4 (1 AMINOETHYL) N (4 PYRIDYL)CYCLOHEXANECARBOXAMIDE; CISPLATIN; DESMOSOMAL CADHERIN; GUANOSINE TRIPHOSPHATASE; PLAKOGLOBIN; PROTEIN RND3; RHO FACTOR; UNCLASSIFIED DRUG;

EID: 84866087012     PISSN: 00219533     EISSN: 14779137     Source Type: Journal    
DOI: 10.1242/jcs.101931     Document Type: Article
Times cited : (13)

References (50)
  • 3
    • 0033785395 scopus 로고    scopus 로고
    • Co-localization of Rac1 and E- cadherin in human epidermal keratinocytes
    • Akhtar, N., Hudson, K. R. and Hotchin, N. A. (2000). Co-localization of Rac1 and E- cadherin in human epidermal keratinocytes. Cell Adhes. Commun. 7, 465-476.
    • (2000) Cell Adhes. Commun. , vol.7 , pp. 465-476
    • Akhtar, N.1    Hudson, K.R.2    Hotchin, N.A.3
  • 5
    • 0032915191 scopus 로고    scopus 로고
    • Desmosomal localization of beta-catenin in the skin of plakoglobin null-mutant mice
    • Bierkamp, C., Schwarz, H., Huber, O. and Kemler, R. (1999). Desmosomal localization of beta-catenin in the skin of plakoglobin null-mutant mice. Development 126, 371-381.
    • (1999) Development , vol.126 , pp. 371-381
    • Bierkamp, C.1    Schwarz, H.2    Huber, O.3    Kemler, R.4
  • 6
    • 33947499358 scopus 로고    scopus 로고
    • The protective role of a small GTPase RhoE against UVB-induced DNA damage in keratinocytes
    • Boswell, S. A., Ongusaha, P. P., Nghiem, P. and Lee, S. W. (2007). The protective role of a small GTPase RhoE against UVB-induced DNA damage in keratinocytes. J. Biol. Chem. 282, 4850-4858.
    • (2007) J. Biol. Chem. , vol.282 , pp. 4850-4858
    • Boswell, S.A.1    Ongusaha, P.P.2    Nghiem, P.3    Lee, S.W.4
  • 9
    • 0030610137 scopus 로고    scopus 로고
    • Direct Ca2+-dependent heterophilic interaction between desmosomal cadherins, desmoglein and desmocollin, contributes to cell-cell adhesion
    • Chitaev, N. A. and Troyanovsky, S. M. (1997). Direct Ca2+-dependent heterophilic interaction between desmosomal cadherins, desmoglein and desmocollin, contributes to cell-cell adhesion. J. Cell Biol. 138, 193-201.
    • (1997) J. Cell Biol. , vol.138 , pp. 193-201
    • Chitaev, N.A.1    Troyanovsky, S.M.2
  • 10
    • 0035072953 scopus 로고    scopus 로고
    • Membrane blebbing during apoptosis results from caspase-mediated activation of ROCK I
    • Coleman, M. L., Sahai, E. A., Yeo, M., Bosch, M., Dewar, A. and Olson, M. F. (2001). Membrane blebbing during apoptosis results from caspase-mediated activation of ROCK I. Nat. Cell Biol. 3, 339-345.
    • (2001) Nat. Cell Biol. , vol.3 , pp. 339-345
    • Coleman, M.L.1    Sahai, E.A.2    Yeo, M.3    Bosch, M.4    Dewar, A.5    Olson, M.F.6
  • 11
    • 0029894664 scopus 로고    scopus 로고
    • Identification of a novel human Rho protein with unusual properties: GTPase deficiency and in vivo farnesylation
    • Foster, R., Hu, K. Q., Lu, Y., Nolan, K. M., Thissen, J. and Settleman, J. (1996). Identification of a novel human Rho protein with unusual properties: GTPase deficiency and in vivo farnesylation. Mol. Cell. Biol. 16, 2689-2699.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 2689-2699
    • Foster, R.1    Hu, K.Q.2    Lu, Y.3    Nolan, K.M.4    Thissen, J.5    Settleman, J.6
  • 12
    • 33847235717 scopus 로고    scopus 로고
    • Scratching the surface of skin development
    • Fuchs, E. (2007). Scratching the surface of skin development. Nature 445, 834-842.
    • (2007) Nature , vol.445 , pp. 834-842
    • Fuchs, E.1
  • 13
    • 20644437528 scopus 로고    scopus 로고
    • Desmoplakin is required early in development for assembly of desmosomes and cytoskeletal linkage
    • Gallicano, G. I., Kouklis, P., Bauer, C., Yin, M., Vasioukhin, V., Degenstein, L. and Fuchs, E. (1998). Desmoplakin is required early in development for assembly of desmosomes and cytoskeletal linkage. J. Cell Biol. 143, 2009-2022.
    • (1998) J. Cell Biol. , vol.143 , pp. 2009-2022
    • Gallicano, G.I.1    Kouklis, P.2    Bauer, C.3    Yin, M.4    Vasioukhin, V.5    Degenstein, L.6    Fuchs, E.7
  • 14
    • 33745848407 scopus 로고    scopus 로고
    • Suppression of canonical Wnt/b-catenin signaling by nuclear plakoglobin recapitulates phenotype of arrhythmogenic right ventricular cardiomyopathy
    • Garcia-Gras, E., Lombardi, R., Giocondo, M. J., Willerson, J. T., Schneider, M. D., Khoury, D. S. and Marian, A. J. (2006). Suppression of canonical Wnt/b-catenin signaling by nuclear plakoglobin recapitulates phenotype of arrhythmogenic right ventricular cardiomyopathy. J. Clin. Invest. 116, 2012-2021.
    • (2006) J. Clin. Invest. , vol.116 , pp. 2012-2021
    • Garcia-Gras, E.1    Lombardi, R.2    Giocondo, M.J.3    Willerson, J.T.4    Schneider, M.D.5    Khoury, D.S.6    Marian, A.J.7
  • 17
    • 77957878007 scopus 로고    scopus 로고
    • The RhoA GEF Syx is a target of Rnd3 and regulated via a Raf1-like ubiquitin-related domain
    • Goh, L. L. and Manser, E. (2010). The RhoA GEF Syx is a target of Rnd3 and regulated via a Raf1-like ubiquitin-related domain. PLoS ONE 5, e12409.
    • (2010) PLoS ONE , vol.5
    • Goh, L.L.1    Manser, E.2
  • 18
    • 0035947772 scopus 로고    scopus 로고
    • E-cadherin suppresses cellular transformation by inhibiting b-catenin signaling in an adhesion-independent manner
    • Gottardi, C. J., Wong, E. and Gumbiner, B. M. (2001). E-cadherin suppresses cellular transformation by inhibiting b-catenin signaling in an adhesion-independent manner. J. Cell Biol. 153, 1049-1060.
    • (2001) J. Cell Biol. , vol.153 , pp. 1049-1060
    • Gottardi, C.J.1    Wong, E.2    Gumbiner, B.M.3
  • 19
    • 0031877714 scopus 로고    scopus 로고
    • RhoE regulates actin cytoskeleton organization and cell migration
    • Guasch, R. M., Scambler, P., Jones, G. E. and Ridley, A. J. (1998). RhoE regulates actin cytoskeleton organization and cell migration. Mol. Cell. Biol. 18, 4761-4771.
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 4761-4771
    • Guasch, R.M.1    Scambler, P.2    Jones, G.E.3    Ridley, A.J.4
  • 23
    • 27944479854 scopus 로고    scopus 로고
    • Rho GTPases: biochemistry and biology
    • Jaffe, A. B. and Hall, A. (2005). Rho GTPases: biochemistry and biology. Annu. Rev. Cell Dev. Biol. 21, 247-269.
    • (2005) Annu. Rev. Cell Dev. Biol. , vol.21 , pp. 247-269
    • Jaffe, A.B.1    Hall, A.2
  • 24
    • 0029076819 scopus 로고
    • Anterior axis duplication in Xenopus induced by the over-expression of the cadherin-binding protein plakoglobin
    • Karnovsky, A. and Klymkowsky, M. W. (1995). Anterior axis duplication in Xenopus induced by the over-expression of the cadherin-binding protein plakoglobin. Proc. Natl. Acad. Sci. USA 92, 4522-4526.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 4522-4526
    • Karnovsky, A.1    Klymkowsky, M.W.2
  • 25
    • 38449101897 scopus 로고    scopus 로고
    • Mechanisms regulating epithelial stratification
    • Koster, M. I. and Roop, D. R. (2007). Mechanisms regulating epithelial stratification. Annu. Rev. Cell Dev. Biol. 23, 93-113.
    • (2007) Annu. Rev. Cell Dev. Biol. , vol.23 , pp. 93-113
    • Koster, M.I.1    Roop, D.R.2
  • 30
    • 77949514452 scopus 로고    scopus 로고
    • Distinct roles for ROCK1 and ROCK2 in the regulation of keratinocyte differentiation
    • Lock, F. E. and Hotchin, N. A. (2009). Distinct roles for ROCK1 and ROCK2 in the regulation of keratinocyte differentiation. PLoS ONE 4, e8190.
    • (2009) PLoS ONE , vol.4
    • Lock, F.E.1    Hotchin, N.A.2
  • 32
    • 39149091017 scopus 로고    scopus 로고
    • Outside-in signaling through integrins and cadherins: a central mechanism to control epidermal growth and differentiation?
    • Müller, E. J., Williamson, L., Kolly, C. and Suter, M. M. (2008). Outside-in signaling through integrins and cadherins: a central mechanism to control epidermal growth and differentiation? J. Invest. Dermatol. 128, 501-516.
    • (2008) J Invest. Dermatol. , vol.128 , pp. 501-516
    • Müller, E.J.1    Williamson, L.2    Kolly, C.3    Suter, M.M.4
  • 33
    • 0034610743 scopus 로고    scopus 로고
    • Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta
    • Nakagawa, T., Zhu, H., Morishima, N., Li, E., Xu, J., Yankner, B. A. and Yuan, J. (2000). Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta. Nature 403, 98-103.
    • (2000) Nature , vol.403 , pp. 98-103
    • Nakagawa, T.1    Zhu, H.2    Morishima, N.3    Li, E.4    Xu, J.5    Yankner, B.A.6    Yuan, J.7
  • 34
    • 35348841509 scopus 로고    scopus 로고
    • Tight junctions/adherens junctions: basic structure and function
    • Niessen, C. M. (2007). Tight junctions/adherens junctions: basic structure and function. J. Invest. Dermatol. 127, 2525-2532.
    • (2007) J. Invest. Dermatol. , vol.127 , pp. 2525-2532
    • Niessen, C.M.1
  • 35
  • 36
    • 33846661640 scopus 로고    scopus 로고
    • RhoE interferes with Rb inactivation and regulates the proliferation and survival of the U87 human glioblastoma cell line
    • Poch, E., Miñambres, R., Mocholí, E., Ivorra, C., Pérez-Aragó, A., Guerri, C., Pérez-Roger, I. and Guasch, R. M. (2007). RhoE interferes with Rb inactivation and regulates the proliferation and survival of the U87 human glioblastoma cell line. Exp. Cell Res. 313, 719-731.
    • (2007) Exp. Cell Res. , vol.313 , pp. 719-731
    • Poch, E.1    Miñambres, R.2    Mocholí, E.3    Ivorra, C.4    Pérez-Aragó, A.5    Guerri, C.6    Pérez-Roger, I.7    Guasch, R.M.8
  • 37
    • 0038655599 scopus 로고    scopus 로고
    • RhoE binds to ROCK I and inhibits downstream signaling
    • Riento, K., Guasch, R. M., Garg, R., Jin, B. and Ridley, A. J. (2003). RhoE binds to ROCK I and inhibits downstream signaling. Mol. Cell. Biol. 23, 4219-4229.
    • (2003) Mol. Cell. Biol. , vol.23 , pp. 4219-4229
    • Riento, K.1    Guasch, R.M.2    Garg, R.3    Jin, B.4    Ridley, A.J.5
  • 38
    • 17144377069 scopus 로고    scopus 로고
    • RhoE function is regulated by ROCK I-mediated phosphorylation
    • Riento, K., Totty, N., Villalonga, P., Garg, R., Guasch, R. and Ridley, A. J. (2005). RhoE function is regulated by ROCK I-mediated phosphorylation. EMBO J. 24, 1170-1180.
    • (2005) EMBO J , vol.24 , pp. 1170-1180
    • Riento, K.1    Totty, N.2    Villalonga, P.3    Garg, R.4    Guasch, R.5    Ridley, A.J.6
  • 39
    • 0035075597 scopus 로고    scopus 로고
    • Caspase-3-mediated cleavage of ROCK I induces MLC phosphorylation and apoptotic membrane blebbing
    • Sebbagh, M., Renvoizé, C., Hamelin, J., Riché, N., Bertoglio, J. and Bréard, J. (2001). Caspase-3-mediated cleavage of ROCK I induces MLC phosphorylation and apoptotic membrane blebbing. Nat. Cell Biol. 3, 346-352.
    • (2001) Nat. Cell Biol. , vol.3 , pp. 346-352
    • Sebbagh, M.1    Renvoizé, C.2    Hamelin, J.3    Riché, N.4    Bertoglio, J.5    Bréard, J.6
  • 41
    • 0033601746 scopus 로고    scopus 로고
    • Ordering the cytochrome c-initiated caspase cascade: hierarchical activation of caspases-2, -3, -6, -7, -8, and -10 in a caspase-9-dependent manner
    • Slee, E. A., Harte, M. T., Kluck, R. M., Wolf, B. B., Casiano, C. A., Newmeyer, D. D., Wang, H. G., Reed, J. C., Nicholson, D. W., Alnemri, E. S. et al. (1999). Ordering the cytochrome c-initiated caspase cascade: hierarchical activation of caspases-2, -3, -6, -7, -8, and -10 in a caspase-9-dependent manner. J. Cell Biol. 144, 281-292.
    • (1999) J. Cell Biol. , vol.144 , pp. 281-292
    • Slee, E.A.1    Harte, M.T.2    Kluck, R.M.3    Wolf, B.B.4    Casiano, C.A.5    Newmeyer, D.D.6    Wang, H.G.7    Reed, J.C.8    Nicholson, D.W.9    Alnemri, E.S.10
  • 42
    • 77955073513 scopus 로고    scopus 로고
    • Desmosomes: adhesive strength and signalling in health and disease
    • Thomason, H. A., Scothern, A., McHarg, S. and Garrod, D. R. (2010). Desmosomes: adhesive strength and signalling in health and disease. Biochem. J. 429, 419-433.
    • (2010) Biochem. J. , vol.429 , pp. 419-433
    • Thomason, H.A.1    Scothern, A.2    McHarg, S.3    Garrod, D.R.4
  • 43
    • 33745326435 scopus 로고    scopus 로고
    • Protective effect of fasudil, a Rho-kinase inhibitor, on chemokine expression, leukocyte recruitment, and hepatocellular apoptosis in septic liver injury
    • Thorlacius, K., Slotta, J. E., Laschke, M. W., Wang, Y., Menger, M. D., Jeppsson, B. and Thorlacius, H. (2006). Protective effect of fasudil, a Rho-kinase inhibitor, on chemokine expression, leukocyte recruitment, and hepatocellular apoptosis in septic liver injury. J. Leukoc. Biol. 79, 923-931.
    • (2006) J. Leukoc. Biol. , vol.79 , pp. 923-931
    • Thorlacius, K.1    Slotta, J.E.2    Laschke, M.W.3    Wang, Y.4    Menger, M.D.5    Jeppsson, B.6    Thorlacius, H.7
  • 45
    • 4444355324 scopus 로고    scopus 로고
    • RhoE inhibits cell cycle progression and Ras-induced transformation
    • Villalonga, P., Guasch, R. M., Riento, K. and Ridley, A. J. (2004). RhoE inhibits cell cycle progression and Ras-induced transformation. Mol. Cell. Biol. 24, 7829-7840.
    • (2004) Mol. Cell. Biol. , vol.24 , pp. 7829-7840
    • Villalonga, P.1    Guasch, R.M.2    Riento, K.3    Ridley, A.J.4
  • 46
    • 0034630161 scopus 로고    scopus 로고
    • The CD95 (APO-1/Fas) and the TRAIL (APO-2L) apoptosis systems
    • Walczak, H. and Krammer, P. H. (2000). The CD95 (APO-1/Fas) and the TRAIL (APO-2L) apoptosis systems. Exp. Cell Res. 256, 58-66.
    • (2000) Exp. Cell Res. , vol.256 , pp. 58-66
    • Walczak, H.1    Krammer, P.H.2
  • 49
    • 85047696569 scopus 로고    scopus 로고
    • gamma-Catenin expression is reduced or absent in a subset of human lung cancers and re-expression inhibits transformed cell growth
    • Winn, R. A., Bremnes, R. M., Bemis, L., Franklin, W. A., Miller, Y. E., Cool, C. and Heasley, L. E. (2002). gamma-Catenin expression is reduced or absent in a subset of human lung cancers and re-expression inhibits transformed cell growth. Oncogene 21, 7497-7506.
    • (2002) Oncogene , vol.21 , pp. 7497-7506
    • Winn, R.A.1    Bremnes, R.M.2    Bemis, L.3    Franklin, W.A.4    Miller, Y.E.5    Cool, C.6    Heasley, L.E.7
  • 50
    • 0034036739 scopus 로고    scopus 로고
    • Differential mechanisms of LEF/TCF family-dependent transcriptional activation by beta-catenin and plakoglobin
    • Zhurinsky, J., Shtutman, M. and Ben-Ze'ev, A. (2000). Differential mechanisms of LEF/TCF family-dependent transcriptional activation by beta-catenin and plakoglobin. Mol. Cell. Biol. 20, 4238-4252.
    • (2000) Mol. Cell. Biol , vol.20 , pp. 4238-4252
    • Zhurinsky, J.1    Shtutman, M.2    Ben-Ze'ev, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.