-
1
-
-
33644875954
-
Neuronal protection by sirtuins in Alzheimer's disease
-
doi:10.1111/j.1471-4159.2005.03492.x
-
Anekonda TS, Reddy PH (2006) Neuronal protection by sirtuins in Alzheimer's disease. J Neurochem 96:305-313. doi:10.1111/j. 1471-4159.2005. 03492.x
-
(2006)
J Neurochem
, vol.96
, pp. 305-313
-
-
Anekonda, T.S.1
Reddy, P.H.2
-
2
-
-
25844518743
-
The many faces of REST oversee epigenetic programming of neuronal genes
-
Ballas N, Mandel G (2005) The many faces of REST oversee epigenetic programming of neuronal genes. Curr Opin Neurobiol 15:500-506
-
(2005)
Curr Opin Neurobiol
, vol.15
, pp. 500-506
-
-
Ballas, N.1
Mandel, G.2
-
3
-
-
42649112047
-
An embryonic stem cell-like gene expression signature in poorly differentiated aggressive human tumors
-
Ben-Porath I, Thomson MW, Carey VJ, Ge R, Bell GW, Regev A, Weinberg RA (2008) An embryonic stem cell-like gene expression signature in poorly differentiated aggressive human tumors. Nat Genet 40:499-507
-
(2008)
Nat Genet
, vol.40
, pp. 499-507
-
-
Ben-Porath, I.1
Thomson, M.W.2
Carey, V.J.3
Ge, R.4
Bell, G.W.5
Regev, A.6
Weinberg, R.A.7
-
4
-
-
34249299791
-
The complex language of chromatin regulation during transcription
-
doi:10.1038/nature05915
-
Berger SL (2007) The complex language of chromatin regulation during transcription. Nature 447:407-412. doi:10.1038/nature05915
-
(2007)
Nature
, vol.447
, pp. 407-412
-
-
Berger, S.L.1
-
5
-
-
70349337904
-
Unexpected expression of a- and b-globin in mesencephalic dopaminergic neurons and glial cells
-
Biagioli M, Pinto M, Cesselli D et al (2009) Unexpected expression of a- and b-globin in mesencephalic dopaminergic neurons and glial cells. Proc Natl Acad Sci USA 106:15454-15459
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 15454-15459
-
-
Biagioli, M.1
Pinto, M.2
Cesselli, D.3
-
6
-
-
12244296117
-
Results of a highresolution genome screen of 437 Alzheimer's disease families
-
Blacker D, Bertram L, Saunders AJ et al (2003) Results of a highresolution genome screen of 437 Alzheimer's disease families. Hum Mol Genet 12:23-32
-
(2003)
Hum Mol Genet
, vol.12
, pp. 23-32
-
-
Blacker, D.1
Bertram, L.2
Saunders, A.J.3
-
7
-
-
1242341923
-
Incipient Alzheimer's disease: Microarray correlation analyses reveal major transcriptional and tumor suppressor responses
-
Blalock EM, Geddes JW, Chen KC et al (2004) Incipient Alzheimer's disease: microarray correlation analyses reveal major transcriptional and tumor suppressor responses. Proc Natl Acad Sci USA 101:2173-2178
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 2173-2178
-
-
Blalock, E.M.1
Geddes, J.W.2
Chen, K.C.3
-
8
-
-
80052099172
-
Microarray analyses of laser-captured hippocampus reveal distinct gray and white matter signatures associated with incipient alzheimer's disease
-
Blalock EM, Buechel HM, Popovic J, Geddes JW, Landfield PW (2011) Microarray analyses of laser-captured hippocampus reveal distinct gray and white matter signatures associated with incipient Alzheimer's disease. J Chem Neuroanat 42:118-126
-
(2011)
J Chem Neuroanat
, vol.42
, pp. 118-126
-
-
Blalock, E.M.1
Buechel, H.M.2
Popovic, J.3
Geddes, J.W.4
Landfield, P.W.5
-
9
-
-
78649898204
-
Concerted changes in transcripts in the prefrontal cortex precede neuropathology in Alzheimer's disease
-
doi:10.1093/brain/ awq258
-
Bossers K, Wirz KTS, Meerhoff GF et al (2010) Concerted changes in transcripts in the prefrontal cortex precede neuropathology in Alzheimer's disease. Brain 133:3699-3723. doi:10.1093/brain/ awq258
-
(2010)
Brain
, vol.133
, pp. 3699-3723
-
-
Bossers, K.1
Wirz, K.T.S.2
Meerhoff, G.F.3
-
10
-
-
0025863618
-
Neuropathological stageing of alzheimerrelated changes
-
(review)
-
Braak H, Braak E (1991) Neuropathological stageing of Alzheimerrelated changes. Acta Neuropathol 82:239-59 (review)
-
(1991)
Acta Neuropathol
, vol.82
, pp. 239-259
-
-
Braak, H.1
Braak, E.2
-
11
-
-
34848839240
-
Clinicopathological concordance and discordance in three monozygotic twin pairs with familial alzheimer's disease
-
doi:10.1136/jnnp.2006.113803
-
Brickell KL, Leverenz JB, Steinbart EJ et al (2007) Clinicopathological concordance and discordance in three monozygotic twin pairs with familial Alzheimer's disease. J Neurol Neurosurg Psychiatr 78:1050-1055. doi:10.1136/jnnp.2006.113803
-
(2007)
J Neurol Neurosurg Psychiatr
, vol.78
, pp. 1050-1055
-
-
Brickell, K.L.1
Leverenz, J.B.2
Steinbart, E.J.3
-
12
-
-
79952709417
-
Analysis of the mitochondrial proteome in multiple sclerosis cortex
-
Broadwater L, Pandit A, Azzam S, Clements R, Vadnal J, Yong VW, Freeman EJ, Gregory RB, McDonough J (2011) Analysis of the mitochondrial proteome in multiple sclerosis cortex. BBA Mol Bas Dis 1812:630-641
-
(2011)
BBA Mol Bas Dis
, vol.1812
, pp. 630-641
-
-
Broadwater, L.1
Pandit, A.2
Azzam, S.3
Clements, R.4
Vadnal, J.5
Yong, V.W.6
Freeman, E.J.7
Gregory, R.B.8
McDonough, J.9
-
13
-
-
20444446595
-
Transcriptional therapy with the histone deacetylase inhibitor trichostatin A ameliorates experimental autoimmune encephalomyelitis
-
Camelo S, Iglesias AH, Hwang D et al (2005) Transcriptional therapy with the histone deacetylase inhibitor trichostatin A ameliorates experimental autoimmune encephalomyelitis. J Neuroimmunol 164:10
-
(2005)
J Neuroimmunol
, vol.164
, pp. 10
-
-
Camelo, S.1
Iglesias, A.H.2
Hwang, D.3
-
14
-
-
77950866465
-
Epigenetic regulation in the pathophysiology of alzheimer's disease
-
doi:10.1016/j.pneurobio.2010.01.002
-
Chouliaras L, Rutten BPF, Kenis G et al (2010) Epigenetic regulation in the pathophysiology of Alzheimer's disease. Prog Neurobiol 90:498-510. doi:10.1016/j.pneurobio.2010.01.002
-
(2010)
Prog Neurobiol
, vol.90
, pp. 498-510
-
-
Chouliaras, L.1
Rutten, B.P.F.2
Kenis, G.3
-
15
-
-
0037010289
-
Gene expression profiling of 12633 genes in alzheimer hippocampal CA1: Transcription and neurotrophic factor downregulation and up-regulation of apoptotic and pro-inflammatory signaling
-
Colangelo V, Schurr J, Ball MJ, Pelaez RP, Bazan NG, Lukiw WJ (2002) Gene expression profiling of 12633 genes in Alzheimer hippocampal CA1: transcription and neurotrophic factor downregulation and up-regulation of apoptotic and pro-inflammatory signaling. J Neurosci Res 70:462-473
-
(2002)
J Neurosci Res
, vol.70
, pp. 462-473
-
-
Colangelo, V.1
Schurr, J.2
Ball, M.J.3
Pelaez, R.P.4
Bazan, N.G.5
Lukiw, W.J.6
-
16
-
-
0035866060
-
Beta-amyloid stimulation of microglia and monocytes results in TNFalphadependent expression of inducible nitric oxide synthase and neuronal apoptosis
-
Combs CK, Karlo JC, Kao SC, Landreth GE (2001) beta-Amyloid stimulation of microglia and monocytes results in TNFalphadependent expression of inducible nitric oxide synthase and neuronal apoptosis. J Neurosci 21:1179-1188
-
(2001)
J Neurosci
, vol.21
, pp. 1179-1188
-
-
Combs, C.K.1
Karlo, J.C.2
Kao, S.C.3
Landreth, G.E.4
-
17
-
-
0027194791
-
Gene dose of apolipoprotein E type 4 allele and the risk of alzheimer's disease in late onset families
-
Corder EH, Saunders AM, Strittmatter WJ et al (1993) Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families. Science 261:921-923
-
(1993)
Science
, vol.261
, pp. 921-923
-
-
Corder, E.H.1
Saunders, A.M.2
Strittmatter, W.J.3
-
18
-
-
79959521749
-
The redox basis of epigenetic modifications: From mechanisms to functional consequences
-
doi:10.1089/ars.2010.3492
-
Cyr AR, Domann FE (2011) The redox basis of epigenetic modifications: from mechanisms to functional consequences. Antioxid Redox Signal 15:551-589. doi:10.1089/ars.2010.3492
-
(2011)
Antioxid Redox Signal
, vol.15
, pp. 551-589
-
-
Cyr, A.R.1
Domann, F.E.2
-
19
-
-
0037072278
-
Nonoverlapping but synergetic tau and APP pathologies in sporadic alzheimer's disease
-
Delacourte A, Sergeant N, Champain D et al (2002) Nonoverlapping but synergetic tau and APP pathologies in sporadic Alzheimer's disease. Neurology 59:398-407
-
(2002)
Neurology
, vol.59
, pp. 398-407
-
-
Delacourte, A.1
Sergeant, N.2
Champain, D.3
-
20
-
-
49549083278
-
Histone deacetylase 6 interacts with the microtubule-associated protein tau
-
doi:10.1111/j.1471-4159.2008.05564.x
-
Ding H, Dolan PJ, Johnson GV (2008) Histone deacetylase 6 interacts with the microtubule-associated protein tau. J Neurochem 106:2119-2130. doi:10.1111/j.1471-4159.2008.05564.x
-
(2008)
J Neurochem
, vol.106
, pp. 2119-2130
-
-
Ding, H.1
Dolan, P.J.2
Johnson, G.V.3
-
21
-
-
77952936173
-
Redox signaling, alkylation (carbonylation) of conserved cysteines inactivates class I histone deacetylases 1, 2, and 3 and antagonizes their transcriptional repressor function
-
doi:10.1074/jbc.M109.089250
-
Doyle K, Fitzpatrick FA (2010) Redox signaling, alkylation (carbonylation) of conserved cysteines inactivates class I histone deacetylases 1, 2, and 3 and antagonizes their transcriptional repressor function. J Biol Chem 285:17417-17424. doi:10.1074/jbc.M109.089250
-
(2010)
J Biol Chem
, vol.285
, pp. 17417-17424
-
-
Doyle, K.1
Fitzpatrick, F.A.2
-
22
-
-
0442307849
-
4-Hydroxynonenal oxidativelymodifies histones: Implications for alzheimer's disease
-
doi:10.1016/j.neulet.2003.11.047
-
Drake J, Petroze R, Castegna A et al (2004) 4-Hydroxynonenal oxidativelymodifies histones: implications for Alzheimer's disease. Neurosci Lett 356:155-158. doi:10.1016/j.neulet.2003.11.047
-
(2004)
Neurosci Lett
, vol.356
, pp. 155-158
-
-
Drake, J.1
Petroze, R.2
Castegna, A.3
-
23
-
-
33747751863
-
Gene expression correlates of neurofibrillary tangles in alzheimer's disease
-
doi:10.1016/j.neurobiolaging.2005.08.013
-
Dunckley T, Beach TG, Ramsey KE et al (2006) Gene expression correlates of neurofibrillary tangles in Alzheimer's disease. Neurobiol Aging 27:1359-1371. doi:10.1016/j.neurobiolaging.2005.08.013
-
(2006)
Neurobiol Aging
, vol.27
, pp. 1359-1371
-
-
Dunckley, T.1
Beach, T.G.2
Ramsey, K.E.3
-
24
-
-
38949103022
-
Epigenetic analysis of the human alpha- and beta-globin gene clusters
-
Fathallah H, Portnoy G, Atweh GF (2008) Epigenetic analysis of the human alpha- and beta-globin gene clusters. Blood Cells Mol Dis 40:166-173
-
(2008)
Blood Cells Mol Dis
, vol.40
, pp. 166-173
-
-
Fathallah, H.1
Portnoy, G.2
Atweh, G.F.3
-
25
-
-
0142157600
-
Histone deacetylase inhibition by sodium butyrate chemotherapy ameliorates the neurodegenerative phenotype in huntington's disease mice
-
Ferrante RJ, Kubilus JK, Lee J et al (2003) Histone deacetylase inhibition by sodium butyrate chemotherapy ameliorates the neurodegenerative phenotype in Huntington's Disease mice. J Neurosci 23:9418-9427
-
(2003)
J Neurosci
, vol.23
, pp. 9418-9427
-
-
Ferrante, R.J.1
Kubilus, J.K.2
Lee, J.3
-
26
-
-
79951916914
-
Neuronal hemoglobin is reduced in alzheimer's disease, argyrophilic grain disease, Parkinson's disease, and dementia with lewy bodies
-
Ferrer I, Gómez A, Carmona M, Huesa G, Porta S, Riera-Codina M, Biagioli M, Gustincich S, Aso E (2011) Neuronal hemoglobin is reduced in Alzheimer's disease, argyrophilic grain disease, Parkinson's disease, and dementia with Lewy bodies. J Alzheimers Dis 23:537-550
-
(2011)
J Alzheimers Dis
, vol.23
, pp. 537-550
-
-
Ferrer, I.1
Gómez, A.2
Carmona, M.3
Huesa, G.4
Porta, S.5
Riera-Codina, M.6
Biagioli, M.7
Gustincich, S.8
Aso, E.9
-
27
-
-
67649310030
-
Dysregulation of histone acetylation in the APP/PS1 mouse model of alzheimer's disease
-
Francis YI, Fà M, Ashraf H, Zhang H, Staniszewski A, Latchman DS, Arancio O (2009) Dysregulation of histone acetylation in the APP/PS1 mouse model of Alzheimer's disease. J Alzheimers Dis 18:131-139
-
(2009)
J Alzheimers Dis
, vol.18
, pp. 131-139
-
-
Francis, Y.I.1
Fà, M.2
Ashraf, H.3
Zhang, H.4
Staniszewski, A.5
Latchman, D.S.6
Arancio, O.7
-
28
-
-
41249098662
-
B-vitamin deprivation induces hyperhomocysteinemia and brain S-adenosylhomocysteine, depletes brain S-adenosylmethionine, and enhances PS1 and BACE expression and amyloid-beta deposition in mice
-
Fuso A, Nicolia V, Cavallaro RA, Ricceri L, D'Anselmi F, Coluccia P, Calamandrei G, Scarpa S (2008) B-vitamin deprivation induces hyperhomocysteinemia and brain S-adenosylhomocysteine, depletes brain S-adenosylmethionine, and enhances PS1 and BACE expression and amyloid-beta deposition in mice. Mol Cell Neurosci 37:731-746
-
(2008)
Mol Cell Neurosci
, vol.37
, pp. 731-746
-
-
Fuso, A.1
Nicolia, V.2
Cavallaro, R.A.3
Ricceri, L.4
D'Anselmi, F.5
Coluccia, P.6
Calamandrei, G.7
Scarpa, S.8
-
29
-
-
78649872779
-
Changes in Presenilin 1 gene methylation pattern in diet-induced B vitamin deficiency
-
Fuso A, Nicolia V, Pasqualato A, Fiorenza MT, Cavallaro RA, Scarpa S (2011) Changes in Presenilin 1 gene methylation pattern in diet-induced B vitamin deficiency. Neurobiol Aging 32:187-199
-
(2011)
Neurobiol Aging
, vol.32
, pp. 187-199
-
-
Fuso, A.1
Nicolia, V.2
Pasqualato, A.3
Fiorenza, M.T.4
Cavallaro, R.A.5
Scarpa, S.6
-
30
-
-
19944431703
-
Neuroprotective effects of phenylbutyrate in the N171-82Q transgenic mouse model of Huntington's disease
-
Gardian G, Browne SE, Choi D-K et al (2005) Neuroprotective effects of phenylbutyrate in the N171-82Q transgenic mouse model of Huntington's disease. J Biol Chem 280:556-563
-
(2005)
J Biol Chem
, vol.280
, pp. 556-563
-
-
Gardian, G.1
Browne, S.E.2
Choi, D.-K.3
-
31
-
-
32244435907
-
Role of genes and environments for explaining alzheimer disease
-
doi:10.1001/archpsyc.63.2.168
-
Gatz M, Reynolds CA, Fratiglioni L et al (2006) Role of genes and environments for explaining Alzheimer disease. Arch Gen Psychiatr 63:168-174. doi:10.1001/archpsyc.63.2.168
-
(2006)
Arch Gen Psychiatr
, vol.63
, pp. 168-174
-
-
Gatz, M.1
Reynolds, C.A.2
Fratiglioni, L.3
-
32
-
-
81955162957
-
Gene expression levels assessed by CA1 pyramidal neuron and regional hippocampal dissections in Alzheimer's disease
-
Ginsberg SD, Alldred MJ, Che S (2012) Gene expression levels assessed by CA1 pyramidal neuron and regional hippocampal dissections in Alzheimer's disease. Neurobiol Dis 45:99-107
-
(2012)
Neurobiol Dis
, vol.45
, pp. 99-107
-
-
Ginsberg, S.D.1
Alldred, M.J.2
Che, S.3
-
33
-
-
0026088977
-
Segregation of a missense mutation in the amyloid precursor protein gene with familial alzheimer's disease
-
doi:10.1038/349704a0
-
Goate A, Chartier-Harlin MC, Mullan M et al (1991) Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease. Nature 349:704-706. doi:10.1038/349704a0
-
(1991)
Nature
, vol.349
, pp. 704-706
-
-
Goate, A.1
Chartier-Harlin, M.C.2
Mullan, M.3
-
34
-
-
84862777943
-
An epigenetic blockade of cognitive functions in the neurodegenerating brain
-
Gräff J, Rei D, Guan JS et al (2012) An epigenetic blockade of cognitive functions in the neurodegenerating brain. Nature 483:222-226
-
(2012)
Nature
, vol.483
, pp. 222-226
-
-
Gräff, J.1
Rei, D.2
Guan, J.S.3
-
35
-
-
58149267462
-
Nicotinamide restores cognition in alzheimer's disease transgenic mice via a mechanism involving sirtuin inhibition and selective reduction of Thr231-phosphotau
-
Green KN, Steffan JS, Martinez-Coria H et al (2008) Nicotinamide restores cognition in Alzheimer's disease transgenic mice via a mechanism involving sirtuin inhibition and selective reduction of Thr231-phosphotau. J Neurosci 28:11500-11510
-
(2008)
J Neurosci
, vol.28
, pp. 11500-11510
-
-
Green, K.N.1
Steffan, J.S.2
Martinez-Coria, H.3
-
36
-
-
0035325163
-
Histone acetylation and chromatin remodeling
-
doi:10.1006/excr.2001.5187
-
Gregory PD, Wagner K, Hörz W (2001) Histone acetylation and chromatin remodeling. Exp Cell Res 265:195-202. doi:10.1006/excr.2001.5187
-
(2001)
Exp Cell Res
, vol.265
, pp. 195-202
-
-
Gregory, P.D.1
Wagner, K.2
Hörz, W.3
-
37
-
-
65549123471
-
HDAC2 negatively regulates memory formation and synaptic plasticity
-
Guan JS, Haggarty SJ, Giacometti E, Dannenberg JH, Joseph N, Gao J, Nieland TJ, Zhou Y, Wang X, Mazitschek R, Bradner JE, DePinho RA, Jaenisch R, Tsai LH (2009) HDAC2 negatively regulates memory formation and synaptic plasticity. Nature 459(7243):55-60
-
(2009)
Nature
, vol.459
, Issue.7243
, pp. 55-60
-
-
Guan, J.S.1
Haggarty, S.J.2
Giacometti, E.3
Dannenberg, J.H.4
Joseph, N.5
Gao, J.6
Nieland, T.J.7
Zhou, Y.8
Wang, X.9
Mazitschek, R.10
Bradner, J.E.11
DePinho, R.A.12
Jaenisch, R.13
Tsai, L.H.14
-
38
-
-
0035341254
-
Mitochondrial abnormalities in alzheimer's disease
-
Hirai K, Aliev G, Nunomura A et al (2001) Mitochondrial abnormalities in Alzheimer's disease. J Neurosci 21:3017-3023
-
(2001)
J Neurosci
, vol.21
, pp. 3017-3023
-
-
Hirai, K.1
Aliev, G.2
Nunomura, A.3
-
39
-
-
0842308109
-
Oxidative stress reduces histone deacetylase 2 activity and enhances IL-8 gene expression: Role of tyrosine nitration
-
doi:10.1016/j.bbrc.2004.01.046
-
Ito K, Hanazawa T, Tomita K et al (2004) Oxidative stress reduces histone deacetylase 2 activity and enhances IL-8 gene expression: role of tyrosine nitration. Biochem Biophys Res Commun 315:240-245. doi:10.1016/j.bbrc.2004.01. 046
-
(2004)
Biochem Biophys Res Commun
, vol.315
, pp. 240-245
-
-
Ito, K.1
Hanazawa, T.2
Tomita, K.3
-
40
-
-
1842778936
-
Elevated S-adenosylhomocysteine in alzheimer brain: Influence on methyltransferases and cognitive function
-
Kennedy BP, Bottiglieri T, Arning E, Ziegler MG, Hansen LA, Masliah E (2004) Elevated S-adenosylhomocysteine in Alzheimer brain: influence on methyltransferases and cognitive function. J Neural Transm 111:547-567
-
(2004)
J Neural Transm
, vol.111
, pp. 547-567
-
-
Kennedy, B.P.1
Bottiglieri, T.2
Arning, E.3
Ziegler, M.G.4
Hansen, L.A.5
Masliah, E.6
-
41
-
-
73949128107
-
Histone deacetylase inhibitors in cancer therapy
-
Lane AA, Chabner BA (2009) Histone deacetylase inhibitors in cancer therapy. J Clin Oncol 10(27):5459-5468
-
(2009)
J Clin Oncol
, vol.10
, Issue.27
, pp. 5459-5468
-
-
Lane, A.A.1
Chabner, B.A.2
-
42
-
-
67049086910
-
Developmentally regulated extended domains of DNA hypomethylation encompass highly transcribed genes of the human beta-globin locus
-
Lathrop MJ, Hsu M, Richardson CA, Olivier EN, Qiu C, Bouhassira EE, Fiering S, Lowrey CH (2009) Developmentally regulated extended domains of DNA hypomethylation encompass highly transcribed genes of the human beta-globin locus. Exp Hematol 37:807-813
-
(2009)
Exp Hematol
, vol.37
, pp. 807-813
-
-
Lathrop, M.J.1
Hsu, M.2
Richardson, C.A.3
Olivier, E.N.4
Qiu, C.5
Bouhassira, E.E.6
Fiering, S.7
Lowrey, C.H.8
-
43
-
-
79953311481
-
HDAC6 a-tubulin deacetylase: A potential therapeutic target in neurodegenerative diseases
-
Li G, Jiang H, Chang M, Xie H, Hu L (2011) HDAC6 a-tubulin deacetylase: a potential therapeutic target in neurodegenerative diseases. J Neurol Sci 304(1-2):1-8
-
(2011)
J Neurol Sci
, vol.304
, Issue.1-2
, pp. 1-8
-
-
Li, G.1
Jiang, H.2
Chang, M.3
Xie, H.4
Hu, L.5
-
44
-
-
43049124437
-
Altered neuronal gene expression in brain regions differentially affected by alzheimer's disease: A reference data set
-
Liang WS, Dunckley T, Beach TG et al (2008) Altered neuronal gene expression in brain regions differentially affected by Alzheimer's disease: a reference data set. Physiol Genomics 33:240-256
-
(2008)
Physiol Genomics
, vol.33
, pp. 240-256
-
-
Liang, W.S.1
Dunckley, T.2
Beach, T.G.3
-
45
-
-
33646359953
-
Molecular characterization of early-stage bladder carcinomas by expression profiles, FGFR3 mutation status, and loss of 9q
-
Lindgren D, Liedberg F, Andersson A et al (2006) Molecular characterization of early-stage bladder carcinomas by expression profiles, FGFR3 mutation status, and loss of 9q. Oncogene 25:2685-2696
-
(2006)
Oncogene
, vol.25
, pp. 2685-2696
-
-
Lindgren, D.1
Liedberg, F.2
Andersson, A.3
-
46
-
-
77950864455
-
Epigenetic changes related to beta-amyloid-implications for alzheimer's disease
-
doi:10.1016/j.jalz.2009.04.457
-
Lithner CU, Hernandez CM, Nordberg A, Sweatt JD (2009) Epigenetic changes related to beta-amyloid-implications for Alzheimer's disease. Alzheimer's Dementia 5:P304. doi:10.1016/j.jalz.2009.04.457
-
(2009)
Alzheimer's Dementia
, vol.5
-
-
Lithner, C.U.1
Hernandez, C.M.2
Nordberg, A.3
Sweatt, J.D.4
-
47
-
-
79958769568
-
Epigenetic mechanisms in alzheimer's disease
-
Mastroeni D, Grover A, Delvaux E, Whiteside C, Coleman PD, Rogers J (2011) Epigenetic mechanisms in Alzheimer's disease. Neurobiol Aging 32:1161-1180
-
(2011)
Neurobiol Aging
, vol.32
, pp. 1161-1180
-
-
Mastroeni, D.1
Grover, A.2
Delvaux, E.3
Whiteside, C.4
Coleman, P.D.5
Rogers, J.6
-
48
-
-
57049151436
-
Epigenetic principles and mechanisms underlying nervous system functions in health and disease
-
Mehler MF (2008) Epigenetic principles and mechanisms underlying nervous system functions in health and disease. Prog Neurobiol 86:305
-
(2008)
Prog Neurobiol
, vol.86
, pp. 305
-
-
Mehler, M.F.1
-
49
-
-
42049116923
-
Alzheimer disease and the role of free radicals in the pathogenesis of the disease
-
Moreira PI, Santos MS, Oliveira CR et al (2008) Alzheimer disease and the role of free radicals in the pathogenesis of the disease. CNS Neurol Disord: Drug Targets 7:3-10
-
(2008)
CNS Neurol Disord: Drug Targets
, vol.7
, pp. 3-10
-
-
Moreira, P.I.1
Santos, M.S.2
Oliveira, C.R.3
-
50
-
-
77952168294
-
Altered histone acetylation is associated with age-dependent memory impairment in mice
-
Peleg S, Sananbenesi F, Zovoilis A, Burkhardt S, Bahari-Javan S, Agis-Balboa RC, Cota P, Wittnam JL, Gogol-Doering A, Opitz L, Salinas-Riester G, Dettenhofer M, Kang H, Farinelli L, Chen W, Fischer A (2010) Altered histone acetylation is associated with age-dependent memory impairment in mice. Science 328:753-756
-
(2010)
Science
, vol.328
, pp. 753-756
-
-
Peleg, S.1
Sananbenesi, F.2
Zovoilis, A.3
Burkhardt, S.4
Bahari-Javan, S.5
Agis-Balboa, R.C.6
Cota, P.7
Wittnam, J.L.8
Gogol-Doering, A.9
Opitz, L.10
Salinas-Riester, G.11
Dettenhofer, M.12
Kang, H.13
Farinelli, L.14
Chen, W.15
Fischer, A.16
-
51
-
-
65949122957
-
Tau-an inhibitor of deacetylase HDAC6 function
-
doi:10.1111/j.1471-4159.2009.06102.x
-
Perez M, Santa-Maria I, Gomez de Barreda E et al (2009) Tau-an inhibitor of deacetylase HDAC6 function. J Neurochem 109:1756-1766. doi:10.1111/j.1471- 4159.2009.06102.x
-
(2009)
J Neurochem
, vol.109
, pp. 1756-1766
-
-
Perez, M.1
Santa-Maria, I.2
Gomez De Barreda, E.3
-
52
-
-
33748454440
-
A key role for the microglial NADPH oxidase in APP-dependent killing of neurons
-
doi:10.1016/j.neurobiolaging.2005.09.036
-
Qin B, Cartier L, Dubois-Dauphin M et al (2006) A key role for the microglial NADPH oxidase in APP-dependent killing of neurons. Neurobiol Aging 27:1577-1587. doi:10.1016/j.neurobiolaging.2005.09.036
-
(2006)
Neurobiol Aging
, vol.27
, pp. 1577-1587
-
-
Qin, B.1
Cartier, L.2
Dubois-Dauphin, M.3
-
53
-
-
62449166389
-
PGC-1alpha expression decreases in the alzheimer disease brain as a function of dementia
-
Qin W, Haroutunian V, Katsel P, Cardozo CP, Ho L, Buxbaum JD, Pasinetti GM (2009) PGC-1alpha expression decreases in the Alzheimer disease brain as a function of dementia. Arch Neurol 66:352-361
-
(2009)
Arch Neurol
, vol.66
, pp. 352-361
-
-
Qin, W.1
Haroutunian, V.2
Katsel, P.3
Cardozo, C.P.4
Ho, L.5
Buxbaum, J.D.6
Pasinetti, G.M.7
-
54
-
-
7044231566
-
Microarray analysis in alzheimer's disease and normal aging
-
Ricciarelli R, d'Abramo C, Massone S, Marinari U, Pronzato M, Tabaton M (2004) Microarray analysis in Alzheimer's disease and normal aging. IUBMB Life 56:349-354
-
(2004)
IUBMB Life
, vol.56
, pp. 349-354
-
-
Ricciarelli, R.1
D'Abramo, C.2
Massone, S.3
Marinari, U.4
Pronzato, M.5
Tabaton, M.6
-
55
-
-
67650667779
-
Neurons express hemoglobin a- and b-chains in rat and human brains
-
Richter F, Meurers BH, Zhu C, Medvedeva VP, Chesselet M-F (2009) Neurons express hemoglobin a- and b-chains in rat and human brains. J Comp Neurol 515:538-547
-
(2009)
J Comp Neurol
, vol.515
, pp. 538-547
-
-
Richter, F.1
Meurers, B.H.2
Zhu, C.3
Medvedeva, V.P.4
Chesselet, M.-F.5
-
56
-
-
67349220155
-
Phenylbutyrate ameliorates cognitive deficit and reduces tau pathology in an alzheimer's disease mouse model
-
doi:10.1038/npp.2008.229
-
Ricobaraza A, Cuadrado-Tejedor M, Pérez-Mediavilla A et al (2009) Phenylbutyrate ameliorates cognitive deficit and reduces tau pathology in an Alzheimer's disease mouse model. Neuropsychopharmacology 34:1721-1732. doi:10.1038/npp.2008.229
-
(2009)
Neuropsychopharmacology
, vol.34
, pp. 1721-1732
-
-
Ricobaraza, A.1
Cuadrado-Tejedor, M.2
Pérez-Mediavilla, A.3
-
57
-
-
0037386621
-
Histone deacetylase inhibitors prevent oxidative neuronal death independent of expanded polyglutamine repeats via an Sp1-dependent pathway
-
Ryu H, Lee J, Olofsson BA et al (2003) Histone deacetylase inhibitors prevent oxidative neuronal death independent of expanded polyglutamine repeats via an Sp1-dependent pathway. Proc Natl Acad Sci 100:4281-4286
-
(2003)
Proc Natl Acad Sci
, vol.100
, pp. 4281-4286
-
-
Ryu, H.1
Lee, J.2
Olofsson, B.A.3
-
58
-
-
61349144869
-
Expression of hemoglobin in rodent neurons
-
Schelshorn DW, Schneider A, Kuschinsky AW, Weber D, Kruger C, Dittgen T, Burgers HF, Sabouri F, Gassler N, Bach A, Martin H, Maurer MH (2009) Expression of hemoglobin in rodent neurons. J Cereb Blood Flow Metabol 29:585-595
-
(2009)
J Cereb Blood Flow Metabol
, vol.29
, pp. 585-595
-
-
Schelshorn, D.W.1
Schneider, A.2
Kuschinsky, A.W.3
Weber, D.4
Kruger, C.5
Dittgen, T.6
Burgers, H.F.7
Sabouri, F.8
Gassler, N.9
Bach, A.10
Martin, H.11
Maurer, M.H.12
-
59
-
-
0029784838
-
Amyloid beta-protein and the genetics of alzheimer's disease
-
Selkoe DJ (1996) Amyloid beta-protein and the genetics of Alzheimer's disease. J Biol Chem 271:18295-18298
-
(1996)
J Biol Chem
, vol.271
, pp. 18295-18298
-
-
Selkoe, D.J.1
-
60
-
-
7944233158
-
Cell biology of protein misfolding: The examples of alzheimer's and Parkinson's diseases
-
doi:10.1038/ncb1104-1054
-
Selkoe DJ (2004) Cell biology of protein misfolding: the examples of Alzheimer's and Parkinson's diseases. Nat Cell Biol 6:1054-1061. doi:10.1038/ncb1104-1054
-
(2004)
Nat Cell Biol
, vol.6
, pp. 1054-1061
-
-
Selkoe, D.J.1
-
61
-
-
34547890019
-
Functions of site-specific histone acetylation and deacetylation
-
(review)
-
Shahbazian MD, Grunstein M (2007) Functions of site-specific histone acetylation and deacetylation. Annu Rev Biochem 76:75-100 (review)
-
(2007)
Annu Rev Biochem
, vol.76
, pp. 75-100
-
-
Shahbazian, M.D.1
Grunstein, M.2
-
62
-
-
68249128477
-
Epigenetic reprogramming during wound healing: Loss of polycomb-mediated silencing may enable upregulation of repair genes
-
doi: 10.1038/embor.2009.102
-
Shaw T, Martin P (2009) Epigenetic reprogramming during wound healing: loss of polycomb-mediated silencing may enable upregulation of repair genes. EMBO Rep 10:881-886. doi: 10.1038/embor.2009.102
-
(2009)
EMBO Rep
, vol.10
, pp. 881-886
-
-
Shaw, T.1
Martin, P.2
-
63
-
-
0346386580
-
Widespread peroxynitrite-mediated damage in alzheimer's disease
-
Smith MA, Richey Harris PL, Sayre LM et al (1997) Widespread peroxynitrite-mediated damage in Alzheimer's disease. J Neurosci 17:2653-2657
-
(1997)
J Neurosci
, vol.17
, pp. 2653-2657
-
-
Smith, M.A.1
Richey Harris, P.L.2
Sayre, L.M.3
-
64
-
-
79958001269
-
The role of histone acetylation in ageassociated memory impairment and alzheimer's disease
-
doi:10.1016/j.nlm.2011.04.002 (review)
-
Stilling RM, Fischer A (2011) The role of histone acetylation in ageassociated memory impairment and Alzheimer's disease. Neurobiol Learn Mem 96:19-26. doi:10.1016/j.nlm.2011.04.002 (review)
-
(2011)
Neurobiol Learn Mem
, vol.96
, pp. 19-26
-
-
Stilling, R.M.1
Fischer, A.2
-
65
-
-
27344435774
-
Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles
-
doi:10.1073/pnas.0506580102
-
Subramanian A, Tamayo P, Mootha VK et al (2005) Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles. Proc Natl Acad Sci 102:15545-15550. doi:10.1073/pnas.0506580102
-
(2005)
Proc Natl Acad Sci
, vol.102
, pp. 15545-15550
-
-
Subramanian, A.1
Tamayo, P.2
Mootha, V.K.3
-
67
-
-
77951530055
-
Genome wide profiling of altered gene expression in the neocortex of alzheimer's disease
-
Tan MG, Chua W-T, Esiri MM et al (2010) Genome wide profiling of altered gene expression in the neocortex of Alzheimer's disease. J Neurosci Res 88:1157-1169
-
(2010)
J Neurosci Res
, vol.88
, pp. 1157-1169
-
-
Tan, M.G.1
Chua, W.-T.2
Esiri, M.M.3
-
68
-
-
34250788651
-
Epigenetic mechanisms in the context of complex diseases
-
van Vliet J, Oates N, Whitelaw E (2007) Epigenetic mechanisms in the context of complex diseases. Cell Mol Life Sci 64:1531-1538
-
(2007)
Cell Mol Life Sci
, vol.64
, pp. 1531-1538
-
-
Van Vliet, J.1
Oates, N.2
Whitelaw, E.3
-
69
-
-
78649981260
-
Functional genomics of brain aging and alzheimer's disease: Focus on selective neuronal vulnerability
-
Wang X, Michaelis ML, Michaelis EK (2010) Functional genomics of brain aging and Alzheimer's disease: focus on selective neuronal vulnerability. Curr Genomics 11:618-633
-
(2010)
Curr Genomics
, vol.11
, pp. 618-633
-
-
Wang, X.1
Michaelis, M.L.2
Michaelis, E.K.3
-
70
-
-
33846640591
-
Alterations in immunological and neurological gene expression patterns in alzheimer's disease tissues
-
Weeraratna AT, Kalehua A, Deleon I et al (2007) Alterations in immunological and neurological gene expression patterns in Alzheimer's disease tissues. Exp Cell Res 313:450-461
-
(2007)
Exp Cell Res
, vol.313
, pp. 450-461
-
-
Weeraratna, A.T.1
Kalehua, A.2
Deleon, I.3
-
71
-
-
33751192706
-
The microglial NADPH oxidase complex as a source of oxidative stress in alzheimer's disease
-
doi:10.1186/1742-2094-3-30
-
Wilkinson BL, Landreth GE (2006) The microglial NADPH oxidase complex as a source of oxidative stress in Alzheimer's disease. J Neuroinflamm 3:30. doi:10.1186/1742-2094-3-30
-
(2006)
J Neuroinflamm
, vol.3
, pp. 30
-
-
Wilkinson, B.L.1
Landreth, G.E.2
-
72
-
-
63349107477
-
Transcriptome analysis of synaptoneurosomes identifies neuroplasticity genes overexpressed in incipient alzheimer's disease
-
doi:10.1371/journal.pone.0004936
-
Williams C, Mehrian Shai R, Wu Y et al (2009) Transcriptome analysis of synaptoneurosomes identifies neuroplasticity genes overexpressed in incipient Alzheimer's disease. Plos One 4:e4936. doi:10.1371/journal.pone.0004936
-
(2009)
Plos One
, vol.4
-
-
Williams, C.1
Mehrian Shai, R.2
Wu, Y.3
-
73
-
-
70350464163
-
Activation of SIRT1 by resveratrol represses transcription of the gene for the cytosolic form of phosphoenolpyruvate carboxykinase (GTP) by deacetylating hepatic nuclear factor 4alpha
-
Yang J, Kong X, Martins-Santos ME, Aleman G, Chaco E, Liu GE, Wu SY, Samols D, Hakimi P, Chiang CM, Hanson RW (2009) Activation of SIRT1 by resveratrol represses transcription of the gene for the cytosolic form of phosphoenolpyruvate carboxykinase (GTP) by deacetylating hepatic nuclear factor 4alpha. J Biol Chem 284(40):27042-27053
-
(2009)
J Biol Chem
, vol.284
, Issue.40
, pp. 27042-27053
-
-
Yang, J.1
Kong, X.2
Martins-Santos, M.E.3
Aleman, G.4
Chaco, E.5
Liu, G.E.6
Wu, S.Y.7
Samols, D.8
Hakimi, P.9
Chiang, C.M.10
Hanson, R.W.11
-
74
-
-
0037343844
-
Defects in expression of genes related to synaptic vesicle trafficking in frontal cortex of alzheimer's disease
-
Yao PJ, Zhu M, Pyun EI, Brooks AI, Therianos S, Meyers VE, Coleman PD (2003) Defects in expression of genes related to synaptic vesicle trafficking in frontal cortex of Alzheimer's disease. Neurobiol Dis 12:97-109
-
(2003)
Neurobiol Dis
, vol.12
, pp. 97-109
-
-
Yao, P.J.1
Zhu, M.2
Pyun, E.I.3
Brooks, A.I.4
Therianos, S.5
Meyers, V.E.6
Coleman, P.D.7
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