메뉴 건너뛰기




Volumn 63, Issue 3, 2010, Pages 199-203

Recent advances in understanding the molecular basis of Paget disease of bone

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PROTEIN P62; RECEPTOR ACTIVATOR OF NUCLEAR FACTOR KAPPA B;

EID: 77749301510     PISSN: 00219746     EISSN: 14724146     Source Type: Journal    
DOI: 10.1136/jcp.2009.064428     Document Type: Review
Times cited : (62)

References (55)
  • 3
    • 53349165206 scopus 로고    scopus 로고
    • Pathogenesis of Paget's disease of bone
    • Ralston SH. Pathogenesis of Paget's disease of bone. Bone 2008;43:819-25.
    • (2008) Bone , vol.43 , pp. 819-825
    • Ralston, S.H.1
  • 4
    • 33846516300 scopus 로고    scopus 로고
    • Is the prevalence of Paget's disease of bone decreasing?
    • Cundy T. Is the prevalence of Paget's disease of bone decreasing? J Bone Miner Res 2006;21(Suppl 2):9-13.
    • (2006) J Bone Miner Res , vol.21 , Issue.SUPPL. 2 , pp. 9-13
    • Cundy, T.1
  • 5
    • 70350774165 scopus 로고    scopus 로고
    • Paget's disease of bone e becoming a rarity?
    • Bastin S, Bird H, Gamble G, et al. Paget's disease of bone e becoming a rarity? Rheumatology (Oxford) 2009;48:1232-5.
    • (2009) Rheumatology (Oxford) , vol.48 , pp. 1232-1235
    • Bastin, S.1    Bird, H.2    Gamble, G.3
  • 6
    • 0032868676 scopus 로고    scopus 로고
    • Cell biology of Paget's disease
    • Reddy SV, Menaa C, Singer FR, et al. Cell biology of Paget's disease. J Bone Miner Res 1999;14(Suppl 2):3-8.
    • (1999) J Bone Miner Res , vol.14 , Issue.SUPPL. 2 , pp. 3-8
    • Reddy, S.V.1    Menaa, C.2    Singer, F.R.3
  • 7
    • 56049117643 scopus 로고    scopus 로고
    • A SQSTM1/p62 mutation linked to Paget's disease increases the osteoclastogenic potential of the bone microenvironment
    • Hiruma Y, Kurihara N, Subler MA, et al. A SQSTM1/p62 mutation linked to Paget's disease increases the osteoclastogenic potential of the bone microenvironment. Hum Mol Genet 2008;17:3708-19.
    • (2008) Hum Mol Genet , vol.17 , pp. 3708-3719
    • Hiruma, Y.1    Kurihara, N.2    Subler, M.A.3
  • 8
    • 58149092378 scopus 로고    scopus 로고
    • Paget's disease of bone: Histologic analysis of 754 patients
    • Seitz S, Priemel M, Zustin J, et al. Paget's disease of bone: histologic analysis of 754 patients. J Bone Miner Res 2009;24:62-9.
    • (2009) J Bone Miner Res , vol.24 , pp. 62-69
    • Seitz, S.1    Priemel, M.2    Zustin, J.3
  • 9
    • 34848912628 scopus 로고    scopus 로고
    • The molecular pathogenesis of Paget disease of bone
    • Layfield R. The molecular pathogenesis of Paget disease of bone. Expert Rev Mol Med 2007;9:1-13.
    • (2007) Expert Rev Mol Med , vol.9 , pp. 1-13
    • Layfield, R.1
  • 10
    • 38449085976 scopus 로고    scopus 로고
    • Ubiquitin-mediated signalling and Paget's disease of bone
    • Layfield R, Shaw B. Ubiquitin-mediated signalling and Paget's disease of bone. BMC Biochem 2007;8(Suppl 1):S5.
    • (2007) BMC Biochem , vol.8 , Issue.SUPPL. 1
    • Layfield, R.1    Shaw, B.2
  • 11
    • 33750555919 scopus 로고    scopus 로고
    • Ubiquitin-binding domains
    • Hurley JH, Lee S, Prag G. Ubiquitin-binding domains. Biochem J 2006;399:361-72.
    • (2006) Biochem J , vol.399 , pp. 361-372
    • Hurley, J.H.1    Lee, S.2    Prag, G.3
  • 12
    • 15344339092 scopus 로고    scopus 로고
    • Loss of ubiquitin-binding associated with Paget's disease of bone p62 (SQSTM1) mutations
    • Cavey JR, Ralston SH, Hocking LJ, et al. Loss of ubiquitin-binding associated with Paget's disease of bone p62 (SQSTM1) mutations. J Bone Miner Res 2005;20:619-24.
    • (2005) J Bone Miner Res , vol.20 , pp. 619-624
    • Cavey, J.R.1    Ralston, S.H.2    Hocking, L.J.3
  • 13
    • 33646597289 scopus 로고    scopus 로고
    • Loss of ubiquitin binding is a unifying mechanism by which mutations of SQSTM1 cause Paget's disease of bone
    • Cavey JR, Ralston SH, Sheppard PW, et al. Loss of ubiquitin binding is a unifying mechanism by which mutations of SQSTM1 cause Paget's disease of bone. Calcif Tissue Int 2006;78:271-7.
    • (2006) Calcif Tissue Int , vol.78 , pp. 271-277
    • Cavey, J.R.1    Ralston, S.H.2    Sheppard, P.W.3
  • 14
    • 43049108052 scopus 로고    scopus 로고
    • Sequestosome 1 (SQSTM1) mutations in Paget's disease of bone from the United States
    • Rhodes EC, Johnson-Pais TL, Singer FR, et al. Sequestosome 1 (SQSTM1) mutations in Paget's disease of bone from the United States. Calcif Tissue Int 2008;82:271-7.
    • (2008) Calcif Tissue Int , vol.82 , pp. 271-277
    • Rhodes, E.C.1    Johnson-Pais, T.L.2    Singer, F.R.3
  • 15
    • 50949105285 scopus 로고    scopus 로고
    • Founder effect in different European countries for the recurrent P392L SQSTM1 mutation in Paget's Disease of Bone
    • Chung PY, Beyens G, Guañabens N, et al. Founder effect in different European countries for the recurrent P392L SQSTM1 mutation in Paget's Disease of Bone. Calcif Tissue Int 2008;83:34-42.
    • (2008) Calcif Tissue Int , vol.83 , pp. 34-42
    • Chung, P.Y.1    Beyens, G.2    Guañabens, N.3
  • 16
    • 19944434345 scopus 로고    scopus 로고
    • Ubiquitin-associated domain mutations of SQSTM1 in Paget's disease of bone: Evidence for a founder effect in patients of British descent
    • Lucas GJ, Hocking LJ, Daroszewska A, et al. Ubiquitin-associated domain mutations of SQSTM1 in Paget's disease of bone: evidence for a founder effect in patients of British descent. J Bone Miner Res 2005;20:227-31.
    • (2005) J Bone Miner Res , vol.20 , pp. 227-231
    • Lucas, G.J.1    Hocking, L.J.2    Daroszewska, A.3
  • 17
    • 58149280230 scopus 로고    scopus 로고
    • Genetic epidemiology of Paget's disease of bone in Italy: Sequestosome1/p62 gene mutational test and haplotype analysis at 5q35 in a large representative series of sporadic and familial Italian cases of Paget's disease of bone
    • Falchetti A, Di Stefano M, Marini F, et al. Genetic epidemiology of Paget's disease of bone in Italy: sequestosome1/p62 gene mutational test and haplotype analysis at 5q35 in a large representative series of sporadic and familial Italian cases of Paget's disease of bone. Calcif Tissue Int 2009;84:20-37.
    • (2009) Calcif Tissue Int , vol.84 , pp. 20-37
    • Falchetti, A.1    Di Stefano, M.2    Marini, F.3
  • 18
    • 4544371010 scopus 로고    scopus 로고
    • Novel UBA domain mutations of SQSTM1 in Paget's disease of bone: Genotype phenotype correlation, functional analysis, and structural consequences
    • Hocking LJ, Lucas GJ, Daroszewska A, et al. Novel UBA domain mutations of SQSTM1 in Paget's disease of bone: genotype phenotype correlation, functional analysis, and structural consequences. J Bone Miner Res 2004;19:1122-7.
    • (2004) J Bone Miner Res , vol.19 , pp. 1122-1127
    • Hocking, L.J.1    Lucas, G.J.2    Daroszewska, A.3
  • 19
    • 65549140668 scopus 로고    scopus 로고
    • Characterization of a non-UBA domain missense mutation of sequestosome 1 (SQSTM1) in Paget's disease of bone
    • Najat D, Garner T, Hagen T, et al. Characterization of a non-UBA domain missense mutation of sequestosome 1 (SQSTM1) in Paget's disease of bone. J Bone Miner Res 2009;24:632-42.
    • (2009) J Bone Miner Res , vol.24 , pp. 632-642
    • Najat, D.1    Garner, T.2    Hagen, T.3
  • 20
    • 70349101680 scopus 로고    scopus 로고
    • Sequestosome 1 mutations in Paget's disease of bone in Australia: Prevalence, genotype/phenotype correlation, and a novel non-UBA domain mutation (P364S) associated with increased NF-kappaB signaling without loss of ubiquitin binding
    • Rea SL, Walsh JP, Ward L, et al. Sequestosome 1 mutations in Paget's disease of bone in Australia: prevalence, genotype/phenotype correlation, and a novel non-UBA domain mutation (P364S) associated with increased NF-kappaB signaling without loss of ubiquitin binding. J Bone Miner Res 2009;24:1216-23.
    • (2009) J Bone Miner Res , vol.24 , pp. 1216-1223
    • Rea, S.L.1    Walsh, J.P.2    Ward, L.3
  • 21
    • 61849097834 scopus 로고    scopus 로고
    • Somatic mutations in SQSTM1 detected in affected tissues from patients with sporadic Paget's disease of bone
    • Merchant A, Smielewska M, Patel N, et al. Somatic mutations in SQSTM1 detected in affected tissues from patients with sporadic Paget's disease of bone. J Bone Miner Res 2009;24:484-94.
    • (2009) J Bone Miner Res , vol.24 , pp. 484-494
    • Merchant, A.1    Smielewska, M.2    Patel, N.3
  • 22
    • 59749096578 scopus 로고    scopus 로고
    • Absence of somatic SQSTM1 mutations in Paget's disease of bone
    • Matthews BG, Naot D, Bava U, et al. Absence of somatic SQSTM1 mutations in Paget's disease of bone. J Clin Endocrinol Metab 2009;94:691-4.
    • (2009) J Clin Endocrinol Metab , vol.94 , pp. 691-694
    • Matthews, B.G.1    Naot, D.2    Bava, U.3
  • 23
    • 37549034220 scopus 로고    scopus 로고
    • Identification of a major locus for Paget's disease on chromosome 10p13 in families of British descent
    • Lucas GJ, Riches PL, Hocking LJ, et al. Identification of a major locus for Paget's disease on chromosome 10p13 in families of British descent. J Bone Miner Res 2008;23:58-63.
    • (2008) J Bone Miner Res , vol.23 , pp. 58-63
    • Lucas, G.J.1    Riches, P.L.2    Hocking, L.J.3
  • 24
    • 70450090282 scopus 로고    scopus 로고
    • Identification of novel genetic variants that predispose to Paget's disease of bone by genome wide association
    • Albagha OME, Visconti MR, Alonso N, et al. Identification of novel genetic variants that predispose to Paget's disease of bone by genome wide association. Bone 2009;44(Suppl 2):224-5.
    • (2009) Bone , vol.44 , Issue.SUPPL. 2 , pp. 224-225
    • Albagha, O.M.E.1    Visconti, M.R.2    Alonso, N.3
  • 25
    • 42049109083 scopus 로고    scopus 로고
    • Failure to detect measles virus ribonucleic acid in bone cells from patients with Paget's disease
    • Matthews BG, Afzal MA, Minor PD, et al. Failure to detect measles virus ribonucleic acid in bone cells from patients with Paget's disease. J Clin Endocrinol Metab 2008;93:398-401.
    • (2008) J Clin Endocrinol Metab , vol.93 , pp. 398-401
    • Matthews, B.G.1    Afzal, M.A.2    Minor, P.D.3
  • 26
    • 0442325388 scopus 로고    scopus 로고
    • The atypical PKC-interacting protein p62 is an important mediator of RANK-activated osteoclastogenesis
    • Durán A, Serrano M, Leitges M, et al. The atypical PKC-interacting protein p62 is an important mediator of RANK-activated osteoclastogenesis. Dev Cell 2004;6:303-9.
    • (2004) Dev Cell , vol.6 , pp. 303-309
    • Durán, A.1    Serrano, M.2    Leitges, M.3
  • 27
    • 70349764552 scopus 로고    scopus 로고
    • The p62 P392L mutation linked to Paget's disease induces activation of human osteoclasts
    • Chamoux E, Couture J, Bisson M, et al. The p62 P392L mutation linked to Paget's disease induces activation of human osteoclasts. Mol Endocrinol 2009;23:1668-80.
    • (2009) Mol Endocrinol , vol.23 , pp. 1668-1680
    • Chamoux, E.1    Couture, J.2    Bisson, M.3
  • 28
    • 27444433045 scopus 로고    scopus 로고
    • The p62 scaffold regulates nerve growth factor-induced NF-kappaB activation by influencing TRAF6 polyubiquitination
    • Wooten MW, Geetha T, Seibenhener ML, et al. The p62 scaffold regulates nerve growth factor-induced NF-kappaB activation by influencing TRAF6 polyubiquitination. J Biol Chem 2005;280:35625- 9.
    • (2005) J Biol Chem , vol.280 , pp. 35625-35629
    • Wooten, M.W.1    Geetha, T.2    Seibenhener, M.L.3
  • 29
    • 33747624440 scopus 로고    scopus 로고
    • The signaling adapter p62 is an important mediator of T helper 2 cell function and allergic airway inflammation
    • Martin P, Diaz-Meco MT, Moscat J. The signaling adapter p62 is an important mediator of T helper 2 cell function and allergic airway inflammation. EMBO J 2006;25:3524-33.
    • (2006) EMBO J , vol.25 , pp. 3524-3533
    • Martin, P.1    Diaz-Meco, M.T.2    Moscat, J.3
  • 30
    • 43049124129 scopus 로고    scopus 로고
    • Deubiquitinating enzyme CYLD negatively regulates RANK signaling and osteoclastogenesis in mice
    • Jin W, Chang M, Paul EM, et al. Deubiquitinating enzyme CYLD negatively regulates RANK signaling and osteoclastogenesis in mice. J Clin Invest 2008;118:1858-66.
    • (2008) J Clin Invest , vol.118 , pp. 1858-1866
    • Jin, W.1    Chang, M.2    Paul, E.M.3
  • 31
    • 84856073856 scopus 로고    scopus 로고
    • Functional Role of p62 (SQSTM1) interaction with deubiquitinating enzyme CYLD in Paget's disease of bone
    • accessed 5 October 2009
    • Sundaram K, Shanmugarajan S, Sudhaker Rao D, et al. Functional Role of p62 (SQSTM1) interaction with deubiquitinating enzyme CYLD in Paget's disease of bone. J Bone Miner Res 2009;24(Suppl 1). http://www.asbmr.org/Meetings/AnnualMeeting/AbstractDetail.aspx?aid= 4746eb24-7fa9-4945-8a0b-cb2d2a6a6e26 (accessed 5 October 2009).
    • (2009) J Bone Miner Res , vol.24 , Issue.SUPPL. 1
    • Sundaram, K.1    Shanmugarajan, S.2    Sudhaker Rao, D.3
  • 32
    • 38549119003 scopus 로고    scopus 로고
    • Gene expression profiling in Paget's disease of bone: Upregulation of interferon signalling pathways in pagetic monocytes and lymphocytes
    • Nagy ZB, Gergely P, Donáth J, et al. Gene expression profiling in Paget's disease of bone: upregulation of interferon signalling pathways in pagetic monocytes and lymphocytes. J Bone Miner Res 2008;23:253-9.
    • (2008) J Bone Miner Res , vol.23 , pp. 253-259
    • Nagy, Z.B.1    Gergely, P.2    Donáth, J.3
  • 33
    • 33846505388 scopus 로고    scopus 로고
    • Differential gene expression in cultured osteoblasts and bone marrow stromal cells from patients with Paget's disease of bone
    • Naot D, Bava U, Matthews B, et al. Differential gene expression in cultured osteoblasts and bone marrow stromal cells from patients with Paget's disease of bone. J Bone Miner Res 2007;22:298-309.
    • (2007) J Bone Miner Res , vol.22 , pp. 298-309
    • Naot, D.1    Bava, U.2    Matthews, B.3
  • 34
    • 67349108375 scopus 로고    scopus 로고
    • Increased circulating Dickkopf-1 in Paget's disease of bone
    • Marshall MJ, Evans SF, Sharp CA, et al. Increased circulating Dickkopf-1 in Paget's disease of bone. Clin Biochem 2009;42:965-9.
    • (2009) Clin Biochem , vol.42 , pp. 965-969
    • Marshall, M.J.1    Evans, S.F.2    Sharp, C.A.3
  • 35
    • 52649121942 scopus 로고    scopus 로고
    • The N-terminus and Phe52 residue of LC3 recruit p62/SQSTM1 into autophagosomes
    • Shvets E, Fass E, Scherz-Shouval R, et al. The N-terminus and Phe52 residue of LC3 recruit p62/SQSTM1 into autophagosomes. J Cell Sci 2008;121:2685-95.
    • (2008) J Cell Sci , vol.121 , pp. 2685-2695
    • Shvets, E.1    Fass, E.2    Scherz-Shouval, R.3
  • 36
    • 58549084167 scopus 로고    scopus 로고
    • Ubiquitin signals autophagic degradation of cytosolic proteins and peroxisomes
    • Kim PK, Hailey DW, Mullen RT, et al. Ubiquitin signals autophagic degradation of cytosolic proteins and peroxisomes. Proc Natl Acad Sci U S A 2008;105:20567-74.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 20567-20574
    • Kim, P.K.1    Hailey, D.W.2    Mullen, R.T.3
  • 37
    • 65549142204 scopus 로고    scopus 로고
    • A role for ubiquitin in selective autophagy
    • Kirkin V, McEwan DG, Novak I, et al. A role for ubiquitin in selective autophagy. Mol Cell 2009;34:259-69.
    • (2009) Mol Cell , vol.34 , pp. 259-269
    • Kirkin, V.1    McEwan, D.G.2    Novak, I.3
  • 38
    • 58149344946 scopus 로고    scopus 로고
    • Midbody ring disposal by autophagy is a post-abscission event of cytokinesis
    • Pohl C, Jentsch S. Midbody ring disposal by autophagy is a post-abscission event of cytokinesis. Nat Cell Biol 2009;11:65-70.
    • (2009) Nat Cell Biol , vol.11 , pp. 65-70
    • Pohl, C.1    Jentsch, S.2
  • 39
    • 66449099090 scopus 로고    scopus 로고
    • Autophagy suppresses tumorigenesis through elimination of p62
    • Mathew R, Karp CM, Beaudoin B, et al. Autophagy suppresses tumorigenesis through elimination of p62. Cell 2009;137:1062-75.
    • (2009) Cell , vol.137 , pp. 1062-1075
    • Mathew, R.1    Karp, C.M.2    Beaudoin, B.3
  • 40
    • 59649092634 scopus 로고    scopus 로고
    • Hypoxia-activated autophagy accelerates degradation of SQSTM1/p62
    • Pursiheimo JP, Rantanen K, Heikkinen PT, et al. Hypoxia-activated autophagy accelerates degradation of SQSTM1/p62. Oncogene 2009;28:334-44.
    • (2009) Oncogene , vol.28 , pp. 334-344
    • Pursiheimo, J.P.1    Rantanen, K.2    Heikkinen, P.T.3
  • 41
    • 63449118087 scopus 로고    scopus 로고
    • Osteosarcoma incidence and survival rates from 1973 to 2004: Data from the Surveillance, Epidemiology, and End Results Program
    • Mirabello L, Troisi RJ, Savage SA. Osteosarcoma incidence and survival rates from 1973 to 2004: data from the Surveillance, Epidemiology, and End Results Program. Cancer 2009;115:1531-43.
    • (2009) Cancer , vol.115 , pp. 1531-1543
    • Mirabello, L.1    Troisi, R.J.2    Savage, S.A.3
  • 42
    • 38949108670 scopus 로고    scopus 로고
    • Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes
    • Klionsky DJ, Abeliovich H, Agostinis P, et al. Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes. Autophagy 2008;4:51-75.
    • (2008) Autophagy , vol.4 , pp. 51-75
    • Klionsky, D.J.1    Abeliovich, H.2    Agostinis, P.3
  • 43
    • 33846479861 scopus 로고    scopus 로고
    • Paget's disease of bone in the French population: Novel SQSTM1 mutations, functional analysis, and genotype-phenotype correlations
    • Collet C, Michou L, Audran M, et al. Paget's disease of bone in the French population: novel SQSTM1 mutations, functional analysis, and genotype-phenotype correlations. J Bone Miner Res 2007;22:310-7.
    • (2007) J Bone Miner Res , vol.22 , pp. 310-317
    • Collet, C.1    Michou, L.2    Audran, M.3
  • 44
    • 39849109338 scopus 로고    scopus 로고
    • Autophagy fights disease through cellular self-digestion
    • Mizushima N, Levine B, Cuervo AM, et al. Autophagy fights disease through cellular self-digestion. Nature 2008;451:1069-75.
    • (2008) Nature , vol.451 , pp. 1069-1075
    • Mizushima, N.1    Levine, B.2    Cuervo, A.M.3
  • 45
    • 22144466919 scopus 로고    scopus 로고
    • Activation of IKK by thymosin alpha1 requires the TRAF6 signalling pathway
    • Zhang P, Chan J, Dragoi AM, et al. Activation of IKK by thymosin alpha1 requires the TRAF6 signalling pathway. EMBO Rep 2005;6:531-7.
    • (2005) EMBO Rep , vol.6 , pp. 531-537
    • Zhang, P.1    Chan, J.2    Dragoi, A.M.3
  • 46
    • 60549093730 scopus 로고    scopus 로고
    • Autophagy inhibition compromises degradation of ubiquitin-proteasome pathway substrates
    • Korolchuk VI, Mansilla A, Menzies FM, et al. Autophagy inhibition compromises degradation of ubiquitin-proteasome pathway substrates. Mol Cell 2009;33:517-27.
    • (2009) Mol Cell , vol.33 , pp. 517-527
    • Korolchuk, V.I.1    Mansilla, A.2    Menzies, F.M.3
  • 47
    • 65549085701 scopus 로고    scopus 로고
    • Cullin3-based polyubiquitination and p62-dependent aggregation of caspase-8 mediate extrinsic apoptosis signaling
    • Jin Z, Li Y, Pitti R, et al. Cullin3-based polyubiquitination and p62-dependent aggregation of caspase-8 mediate extrinsic apoptosis signaling. Cell 2009;137:721-35.
    • (2009) Cell , vol.137 , pp. 721-735
    • Jin, Z.1    Li, Y.2    Pitti, R.3
  • 48
    • 33846009075 scopus 로고    scopus 로고
    • Mutation of the sequestosome 1 (p62) gene increases osteoclastogenesis but does not induce Paget disease
    • Kurihara N, Hiruma Y, Zhou H, et al. Mutation of the sequestosome 1 (p62) gene increases osteoclastogenesis but does not induce Paget disease. J Clin Invest 2007;117:133-42.
    • (2007) J Clin Invest , vol.117 , pp. 133-142
    • Kurihara, N.1    Hiruma, Y.2    Zhou, H.3
  • 49
    • 70449962436 scopus 로고    scopus 로고
    • Knock-in of the P392L mutation of SQSTM1 causes a phenotype similar to Paget's disease in mice
    • Daroszewska A, Rojas J, Rose L, et al. Knock-in of the P392L mutation of SQSTM1 causes a phenotype similar to Paget's disease in mice. Calcif Tissue Int 2008;82:S34-5.
    • (2008) Calcif Tissue Int , vol.82
    • Daroszewska, A.1    Rojas, J.2    Rose, L.3
  • 50
    • 77749307140 scopus 로고    scopus 로고
    • The P392L mutation of SQSTM1 causes a Paget's disease-like phenotype in mice
    • accessed 5 October 2009
    • Daroszewska A, Van't Hof R, Rose L, et al. The P392L mutation of SQSTM1 causes a Paget's disease-like phenotype in mice. J Bone Miner Res 2009;24(Suppl 1). http://www.asbmr.org/Meetings/ AnnualMeeting/AbstractDetail.aspx?aid=95738926-f13a-4dfc-af95-b58f6759122e (accessed 5 October 2009).
    • (2009) J Bone Miner Res , vol.24 , Issue.SUPPL. 1
    • Daroszewska, A.1    Van't Hof, R.2    Rose, L.3
  • 51
    • 77749311549 scopus 로고    scopus 로고
    • Daroszewska A, Rose L, Rose K, et al. Development of a novel animal model for the syndrome of inclusion body myopathy, Paget's disease and fronto-temporal dementia. Abstract OP27 presented at ECTS 36th Symposium on Calcified Tissues, Vienna, May 2009. 〈http://abstract.mci-group.com/cgi- bin/mc/printabs.pl?APP=ECTS2009-abstract&TEMPLATE=&keyf= 0497&showHide=show&client=〉. (accessed 5 October 2009).
    • Daroszewska A, Rose L, Rose K, et al. Development of a novel animal model for the syndrome of inclusion body myopathy, Paget's disease and fronto-temporal dementia. Abstract OP27 presented at ECTS 36th Symposium on Calcified Tissues, Vienna, May 2009. 〈http://abstract.mci-group.com/cgi- bin/mc/printabs.pl?APP=ECTS2009-abstract&TEMPLATE=&keyf= 0497&showHide=show&client=〉. (accessed 5 October 2009).
  • 52
    • 69449103157 scopus 로고    scopus 로고
    • Viruses and arrested autophagosome development
    • Taylor MP, Jackson WT. Viruses and arrested autophagosome development. Autophagy 2009;5:870-1.
    • (2009) Autophagy , vol.5 , pp. 870-871
    • Taylor, M.P.1    Jackson, W.T.2
  • 53
    • 0031555892 scopus 로고    scopus 로고
    • Low micromolar levels of hydrogen peroxide and proteasome inhibitors induce the 60-kDa A170 stress protein in murine peritoneal macrophages
    • Ishii T, Yanagawa T, Yuki K, et al. Low micromolar levels of hydrogen peroxide and proteasome inhibitors induce the 60-kDa A170 stress protein in murine peritoneal macrophages. Biochem Biophys Res Commun 1997;232:33-7.
    • (1997) Biochem Biophys Res Commun , vol.232 , pp. 33-37
    • Ishii, T.1    Yanagawa, T.2    Yuki, K.3
  • 54
    • 46749127771 scopus 로고    scopus 로고
    • Pathogenesis and management of Paget's disease of bone
    • Ralston SH, Langston AL, Reid IR. Pathogenesis and management of Paget's disease of bone. Lancet 2008;372:155-63.
    • (2008) Lancet , vol.372 , pp. 155-163
    • Ralston, S.H.1    Langston, A.L.2    Reid, I.R.3
  • 55
    • 77953424429 scopus 로고    scopus 로고
    • Randomised trial of intensive bisphosphonate treatment versus symptomatic management in Paget's disease of bone
    • Published Online First: 6 July, doi:10.1359/jbmr.090709
    • Langston AL, Campbell MK, Fraser WD, et al. Randomised trial of intensive bisphosphonate treatment versus symptomatic management in Paget's disease of bone. J Bone Miner Res Published Online First: 6 July 2009. doi:10.1359/jbmr.090709.
    • (2009) J Bone Miner Res
    • Langston, A.L.1    Campbell, M.K.2    Fraser, W.D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.