메뉴 건너뛰기




Volumn 43, Issue 5, 2008, Pages 819-825

Pathogenesis of Paget's disease of bone

Author keywords

Genetic; Osteoblast; Osteoclast; Paget's disease; RANK

Indexed keywords

DNA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PROTEIN P62; PROTEIN P97; RECEPTOR ACTIVATOR OF NUCLEAR FACTOR KAPPA B; VIRUS PROTEIN;

EID: 53349165206     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bone.2008.06.015     Document Type: Review
Times cited : (75)

References (114)
  • 1
    • 84969213492 scopus 로고    scopus 로고
    • Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls
    • Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature 447 (2007) 661-678
    • (2007) Nature , vol.447 , pp. 661-678
  • 2
    • 0037334534 scopus 로고    scopus 로고
    • Serum osteoprotegerin and its ligand in Paget's disease of bone: relationship to disease activity and effect of treatment with bisphosphonates
    • Alvarez L., Peris P., Guanabens N., Vidal S., Ros I., Pons F., et al. Serum osteoprotegerin and its ligand in Paget's disease of bone: relationship to disease activity and effect of treatment with bisphosphonates. Arthritis Rheum. 48 (2003) 824-828
    • (2003) Arthritis Rheum. , vol.48 , pp. 824-828
    • Alvarez, L.1    Peris, P.2    Guanabens, N.3    Vidal, S.4    Ros, I.5    Pons, F.6
  • 3
    • 0022548561 scopus 로고
    • Measles virus RNA detected in Paget's disease bone tissue by in situ hybridization
    • Basle M.F., Fournier J.G., Rozenblatt S., Rebel A., and Bouteille M. Measles virus RNA detected in Paget's disease bone tissue by in situ hybridization. J. Gen. Virol. 67 Pt 5 (1986) 907-913
    • (1986) J. Gen. Virol. , vol.67 , Issue.PART 5 , pp. 907-913
    • Basle, M.F.1    Fournier, J.G.2    Rozenblatt, S.3    Rebel, A.4    Bouteille, M.5
  • 4
    • 0023474352 scopus 로고
    • Paramyxovirus-like inclusions in two cases of pycnodysostosis
    • Beneton M.N.C., Harris S., and Kanis J.A. Paramyxovirus-like inclusions in two cases of pycnodysostosis. Metab. Bone Dis. Rel. Res. 8 (1987) 211-217
    • (1987) Metab. Bone Dis. Rel. Res. , vol.8 , pp. 211-217
    • Beneton, M.N.C.1    Harris, S.2    Kanis, J.A.3
  • 5
    • 34548147590 scopus 로고    scopus 로고
    • Identification of sex-specific associations between polymorphisms of the osteoprotegerin gene, TNFRSF11B, and Paget's disease of bone
    • Beyens G., Daroszewska A., de F.F., Fransen E., Vanhoenacker F., Verbruggen L., et al. Identification of sex-specific associations between polymorphisms of the osteoprotegerin gene, TNFRSF11B, and Paget's disease of bone. J. Bone Miner. Res. 22 (2007) 1062-1071
    • (2007) J. Bone Miner. Res. , vol.22 , pp. 1062-1071
    • Beyens, G.1    Daroszewska, A.2    de, F.F.3    Fransen, E.4    Vanhoenacker, F.5    Verbruggen, L.6
  • 7
    • 0026488211 scopus 로고
    • Paramyxovirus-like nuclear inclusions identical to those of Paget's disease of bone detected in giant cells of primary oxalosis
    • Bianco P., Silvestrini G., Ballanti P., and Bonucci E. Paramyxovirus-like nuclear inclusions identical to those of Paget's disease of bone detected in giant cells of primary oxalosis. Virchows Archiv - A, Pathological Anatomy & Histopathology 421 (1992) 427-433
    • (1992) Virchows Archiv - A, Pathological Anatomy & Histopathology , vol.421 , pp. 427-433
    • Bianco, P.1    Silvestrini, G.2    Ballanti, P.3    Bonucci, E.4
  • 10
    • 33646597289 scopus 로고    scopus 로고
    • Loss of ubiquitin binding is a unifying mechanism by which mutations of SQSTM1 cause Paget's disease of bone
    • Cavey J.R., Ralston S.H., Sheppard P.W., Ciani B., Gallagher T.R., Long J.E., et al. Loss of ubiquitin binding is a unifying mechanism by which mutations of SQSTM1 cause Paget's disease of bone. Calcif. Tissue Int. 78 (2006) 271-277
    • (2006) Calcif. Tissue Int. , vol.78 , pp. 271-277
    • Cavey, J.R.1    Ralston, S.H.2    Sheppard, P.W.3    Ciani, B.4    Gallagher, T.R.5    Long, J.E.6
  • 11
    • 0141844580 scopus 로고    scopus 로고
    • Structure of the UBA domain of p62 (SQSTM1) and implications for mutations which cause Paget's disease of bone
    • Ciani B., Layfield R., Cavey J.R., Sheppard P.W., and Searle M.S. Structure of the UBA domain of p62 (SQSTM1) and implications for mutations which cause Paget's disease of bone. J. Biol. Chem. 278 (2003) 37409-37412
    • (2003) J. Biol. Chem. , vol.278 , pp. 37409-37412
    • Ciani, B.1    Layfield, R.2    Cavey, J.R.3    Sheppard, P.W.4    Searle, M.S.5
  • 13
    • 33846479861 scopus 로고    scopus 로고
    • Paget's disease of bone in the French population: novel SQSTM1 mutations, functional analysis, and genotype-phenotype correlations
    • Collet C., Michou L., Audran M., Chasseigneaux S., Hilliquin P., Bardin T., et al. Paget's disease of bone in the French population: novel SQSTM1 mutations, functional analysis, and genotype-phenotype correlations. J. Bone Miner. Res. 22 (2007) 310-317
    • (2007) J. Bone Miner. Res. , vol.22 , pp. 310-317
    • Collet, C.1    Michou, L.2    Audran, M.3    Chasseigneaux, S.4    Hilliquin, P.5    Bardin, T.6
  • 15
    • 11944270643 scopus 로고    scopus 로고
    • Paget's disease of bone in New Zealand: continued decline in disease severity
    • Cundy H.R., Gamble G., Wattie D., Rutland M., and Cundy T. Paget's disease of bone in New Zealand: continued decline in disease severity. Calcif. Tissue Int. 75 (2004) 358-364
    • (2004) Calcif. Tissue Int. , vol.75 , pp. 358-364
    • Cundy, H.R.1    Gamble, G.2    Wattie, D.3    Rutland, M.4    Cundy, T.5
  • 16
    • 18544371504 scopus 로고    scopus 로고
    • A mutation in the gene TNFRSF11B encoding osteoprotegerin causes an idiopathic hyperphosphatasia phenotype
    • Cundy T., Hegde M., Naot D., Chong B., King A., Wallace R., et al. A mutation in the gene TNFRSF11B encoding osteoprotegerin causes an idiopathic hyperphosphatasia phenotype. Hum. Mol. Genet. 11 (2002) 2119-2127
    • (2002) Hum. Mol. Genet. , vol.11 , pp. 2119-2127
    • Cundy, T.1    Hegde, M.2    Naot, D.3    Chong, B.4    King, A.5    Wallace, R.6
  • 18
    • 0027484047 scopus 로고
    • Abnormalities in osteoclast precursors and marrow accessory cells in Paget's disease
    • Demulder A., Takahashi S., Singer F.R., Hosking D.J., and Roodman G.D. Abnormalities in osteoclast precursors and marrow accessory cells in Paget's disease. Endocrinology 133 (1993) 1978-1982
    • (1993) Endocrinology , vol.133 , pp. 1978-1982
    • Demulder, A.1    Takahashi, S.2    Singer, F.R.3    Hosking, D.J.4    Roodman, G.D.5
  • 19
    • 0019965276 scopus 로고
    • European distribution of Paget's disease of bone
    • Detheridge F.M., Guyer P.B., and Barker D.J. European distribution of Paget's disease of bone. Br. Med. J. 285 (1982) 1005-1008
    • (1982) Br. Med. J. , vol.285 , pp. 1005-1008
    • Detheridge, F.M.1    Guyer, P.B.2    Barker, D.J.3
  • 20
    • 0442325388 scopus 로고    scopus 로고
    • The atypical PKC-interacting protein p62 is an important mediator of RANK-activated osteoclastogenesis
    • Duran A., Serrano M., Leitges M., Flores J.M., Picard S., Brown J.P., et al. The atypical PKC-interacting protein p62 is an important mediator of RANK-activated osteoclastogenesis. Dev. Cell 6 (2004) 303-309
    • (2004) Dev. Cell , vol.6 , pp. 303-309
    • Duran, A.1    Serrano, M.2    Leitges, M.3    Flores, J.M.4    Picard, S.5    Brown, J.P.6
  • 21
    • 2342493320 scopus 로고    scopus 로고
    • Familial Paget's disease in The Netherlands: occurrence, identification of new mutations in the sequestosome 1 gene, and their clinical associations
    • Eekhoff E.W., Karperien M., Houtsma D., Zwinderman A.H., Dragoiescu C., Kneppers A.L., et al. Familial Paget's disease in The Netherlands: occurrence, identification of new mutations in the sequestosome 1 gene, and their clinical associations. Arthritis Rheum. 50 (2004) 1650-1654
    • (2004) Arthritis Rheum. , vol.50 , pp. 1650-1654
    • Eekhoff, E.W.1    Karperien, M.2    Houtsma, D.3    Zwinderman, A.H.4    Dragoiescu, C.5    Kneppers, A.L.6
  • 22
    • 8644267864 scopus 로고    scopus 로고
    • Two novel mutations at exon 8 of Sequestosome 1 gene (SQSTM1) in an Italian series of patients affected by Paget's disease of bone (PDB)
    • Falchetti A., Di Stefano M., Marini F., Del Monte F., Mavilia C., Strigoli D., et al. Two novel mutations at exon 8 of Sequestosome 1 gene (SQSTM1) in an Italian series of patients affected by Paget's disease of bone (PDB). J. Bone Miner. Res. 19 (2004) 1013-1017
    • (2004) J. Bone Miner. Res. , vol.19 , pp. 1013-1017
    • Falchetti, A.1    Di Stefano, M.2    Marini, F.3    Del Monte, F.4    Mavilia, C.5    Strigoli, D.6
  • 23
    • 18144362892 scopus 로고    scopus 로고
    • The LIM protein Ajuba influences interleukin-1-induced NF-kappaB activation by affecting the assembly and activity of the protein kinase Czeta/p62/TRAF6 signaling complex
    • Feng Y., and Longmore G.D. The LIM protein Ajuba influences interleukin-1-induced NF-kappaB activation by affecting the assembly and activity of the protein kinase Czeta/p62/TRAF6 signaling complex. Mol. Cell Biol. 25 (2005) 4010-4022
    • (2005) Mol. Cell Biol. , vol.25 , pp. 4010-4022
    • Feng, Y.1    Longmore, G.D.2
  • 24
    • 33846995642 scopus 로고    scopus 로고
    • The LIM protein, Limd1, regulates AP-1 activation through an interaction with Traf6 to influence osteoclast development
    • Feng Y., Zhao H., Luderer H.F., Epple H., Faccio R., Ross F.P., et al. The LIM protein, Limd1, regulates AP-1 activation through an interaction with Traf6 to influence osteoclast development. J. Biol. Chem. 282 (2007) 39-48
    • (2007) J. Biol. Chem. , vol.282 , pp. 39-48
    • Feng, Y.1    Zhao, H.2    Luderer, H.F.3    Epple, H.4    Faccio, R.5    Ross, F.P.6
  • 28
    • 2942709744 scopus 로고    scopus 로고
    • Identification of SQSTM1 mutations in familial Paget's disease in Australian pedigrees
    • Good D.A., Busfield F., Fletcher B.H., Lovelock P.K., Duffy D.L., Kesting J.B., et al. Identification of SQSTM1 mutations in familial Paget's disease in Australian pedigrees. Bone 35 (2004) 277-282
    • (2004) Bone , vol.35 , pp. 277-282
    • Good, D.A.1    Busfield, F.2    Fletcher, B.H.3    Lovelock, P.K.4    Duffy, D.L.5    Kesting, J.B.6
  • 29
    • 0025742622 scopus 로고
    • Canine distemper virus localised in bone cells of patients with Paget's disease
    • Gordon M.T., Anderson D.C., and Sharpe P.T. Canine distemper virus localised in bone cells of patients with Paget's disease. Bone 12 (1991) 195-201
    • (1991) Bone , vol.12 , pp. 195-201
    • Gordon, M.T.1    Anderson, D.C.2    Sharpe, P.T.3
  • 31
    • 0031778038 scopus 로고    scopus 로고
    • Paget's disease of bone: evidence for a susceptibility locus on chromosome 18q and for genetic heterogeneity
    • Haslam S.I., Van Hul W., Morales-Piga A., Balemans W., San Millan J.L., Nakatsuka K., et al. Paget's disease of bone: evidence for a susceptibility locus on chromosome 18q and for genetic heterogeneity. J. Bone Miner. Res. 13 (1998) 911-917
    • (1998) J. Bone Miner. Res. , vol.13 , pp. 911-917
    • Haslam, S.I.1    Van Hul, W.2    Morales-Piga, A.3    Balemans, W.4    San Millan, J.L.5    Nakatsuka, K.6
  • 32
    • 0033713488 scopus 로고    scopus 로고
    • A negative search for a paramyxoviral etiology of Paget's disease of bone: molecular, immunological, and ultrastructural studies in UK patients
    • Helfrich M.H., Hobson R.P., Grabowski P.S., Zurbriggen A., Cosby S.L., Dickson G.R., et al. A negative search for a paramyxoviral etiology of Paget's disease of bone: molecular, immunological, and ultrastructural studies in UK patients. J. Bone Miner. Res. 15 (2000) 2315-2329
    • (2000) J. Bone Miner. Res. , vol.15 , pp. 2315-2329
    • Helfrich, M.H.1    Hobson, R.P.2    Grabowski, P.S.3    Zurbriggen, A.4    Cosby, S.L.5    Dickson, G.R.6
  • 33
    • 0034065196 scopus 로고    scopus 로고
    • Familial Paget's disease of bone: patterns of inheritance and frequency of linkage to chromosome 18q
    • Hocking L., Slee F., Haslam S.I., Cundy T., Nicholson G., Van H.W., et al. Familial Paget's disease of bone: patterns of inheritance and frequency of linkage to chromosome 18q. Bone 26 (2000) 577-580
    • (2000) Bone , vol.26 , pp. 577-580
    • Hocking, L.1    Slee, F.2    Haslam, S.I.3    Cundy, T.4    Nicholson, G.5    Van, H.W.6
  • 34
    • 0034763552 scopus 로고    scopus 로고
    • Genomewide search in familial Paget disease of bone shows evidence of genetic heterogeneity with candidate loci on chromosomes 2q36, 10p13, and 5q35
    • Hocking L.J., Herbert C.A., Nicholls R.K., Williams F., Bennett S.T., Cundy T., et al. Genomewide search in familial Paget disease of bone shows evidence of genetic heterogeneity with candidate loci on chromosomes 2q36, 10p13, and 5q35. Am. J. Hum. Genet. 69 (2001) 1055-1061
    • (2001) Am. J. Hum. Genet. , vol.69 , pp. 1055-1061
    • Hocking, L.J.1    Herbert, C.A.2    Nicholls, R.K.3    Williams, F.4    Bennett, S.T.5    Cundy, T.6
  • 35
    • 4544371010 scopus 로고    scopus 로고
    • Novel UBA domain mutations of SQSTM1 in Paget's disease of bone: genotype phenotype correlation, functional analysis and structural consequences
    • Hocking L.J., Lucas G., Daroszewska A., Cundy T., Nicholson G.C., Donath J., et al. Novel UBA domain mutations of SQSTM1 in Paget's disease of bone: genotype phenotype correlation, functional analysis and structural consequences. J. Bone Miner. Res. 19 (2004) 1122-1127
    • (2004) J. Bone Miner. Res. , vol.19 , pp. 1122-1127
    • Hocking, L.J.1    Lucas, G.2    Daroszewska, A.3    Cundy, T.4    Nicholson, G.C.5    Donath, J.6
  • 37
    • 0028044531 scopus 로고
    • Interleukin-6, IL-6 receptor, and IL-6 nuclear factor gene expression in Paget's disease
    • Hoyland J.A., Freemont A.J., and Sharpe P.T. Interleukin-6, IL-6 receptor, and IL-6 nuclear factor gene expression in Paget's disease. J. Bone Miner. Res. 9 (1994) 75-80
    • (1994) J. Bone Miner. Res. , vol.9 , pp. 75-80
    • Hoyland, J.A.1    Freemont, A.J.2    Sharpe, P.T.3
  • 38
    • 0028031320 scopus 로고
    • Up-regulation of c-fos protooncogene expression in pagetic osteoclasts
    • Hoyland J.A., and Sharpe P.T. Up-regulation of c-fos protooncogene expression in pagetic osteoclasts. J. Bone Miner. Res. 8 (1994) 1191-1195
    • (1994) J. Bone Miner. Res. , vol.8 , pp. 1191-1195
    • Hoyland, J.A.1    Sharpe, P.T.2
  • 39
    • 0033987358 scopus 로고    scopus 로고
    • Mutations in TNFRSF11A, affecting the signal peptide of RANK, cause familial expansile osteolysis
    • Hughes A.E., Ralston S.H., Marken J., Bell C., MacPherson H., Wallace R.G., et al. Mutations in TNFRSF11A, affecting the signal peptide of RANK, cause familial expansile osteolysis. Nat. Genet. 24 (2000) 45-48
    • (2000) Nat. Genet. , vol.24 , pp. 45-48
    • Hughes, A.E.1    Ralston, S.H.2    Marken, J.3    Bell, C.4    MacPherson, H.5    Wallace, R.G.6
  • 41
    • 35548973892 scopus 로고    scopus 로고
    • DNA sequencing: bench to bedside and beyond
    • Hutchison III C.A. DNA sequencing: bench to bedside and beyond. Nucleic Acids Res. 35 (2007) 6227-6237
    • (2007) Nucleic Acids Res. , vol.35 , pp. 6227-6237
    • Hutchison III, C.A.1
  • 44
    • 36849089101 scopus 로고    scopus 로고
    • Homeostatic levels of p62 control cytoplasmic inclusion body formation in autophagy-deficient mice
    • Komatsu M., Waguri S., Koike M., Sou Y.S., Ueno T., Hara T., et al. Homeostatic levels of p62 control cytoplasmic inclusion body formation in autophagy-deficient mice. Cell 131 (2007) 1149-1163
    • (2007) Cell , vol.131 , pp. 1149-1163
    • Komatsu, M.1    Waguri, S.2    Koike, M.3    Sou, Y.S.4    Ueno, T.5    Hara, T.6
  • 45
    • 18244381306 scopus 로고    scopus 로고
    • Clinical delineation and localization to chromosome 9p13.3-p12 of a unique dominant disorder in four families: hereditary inclusion body myopathy, Paget disease of bone, and frontotemporal dementia
    • Kovach M.J., Waggoner B., Leal S.M., Gelber D., Khardori R., Levenstien M.A., et al. Clinical delineation and localization to chromosome 9p13.3-p12 of a unique dominant disorder in four families: hereditary inclusion body myopathy, Paget disease of bone, and frontotemporal dementia. Mol. Genet. Metab. 74 (2001) 458-475
    • (2001) Mol. Genet. Metab. , vol.74 , pp. 458-475
    • Kovach, M.J.1    Waggoner, B.2    Leal, S.M.3    Gelber, D.4    Khardori, R.5    Levenstien, M.A.6
  • 46
    • 0025348283 scopus 로고
    • Atypical multinucleated cells form in long-term marrow cultures from patients with Paget's disease
    • Kukita A., Chenu C., McManus L.M., Mundy G.R., and Roodman G.D. Atypical multinucleated cells form in long-term marrow cultures from patients with Paget's disease. J. Clin. Invest. 85 (1990) 1280-1286
    • (1990) J. Clin. Invest. , vol.85 , pp. 1280-1286
    • Kukita, A.1    Chenu, C.2    McManus, L.M.3    Mundy, G.R.4    Roodman, G.D.5
  • 47
    • 33846009075 scopus 로고    scopus 로고
    • Mutation of the sequestosome 1 (p62) gene increases osteoclastogenesis but does not induce Paget disease
    • Kurihara N., Hiruma Y., Zhou H., Subler M.A., Dempster D.W., Singer F.R., et al. Mutation of the sequestosome 1 (p62) gene increases osteoclastogenesis but does not induce Paget disease. J. Clin. Invest. 117 (2007) 133-142
    • (2007) J. Clin. Invest. , vol.117 , pp. 133-142
    • Kurihara, N.1    Hiruma, Y.2    Zhou, H.3    Subler, M.A.4    Dempster, D.W.5    Singer, F.R.6
  • 48
    • 15244347056 scopus 로고    scopus 로고
    • Role of TAFII-17, a VDR binding protein, in the increased osteoclast formation in Paget's Disease
    • Kurihara N., Reddy S.V., Araki N., Ishizuka S., Ozono K., Cornish J., et al. Role of TAFII-17, a VDR binding protein, in the increased osteoclast formation in Paget's Disease. J. Bone Miner. Res. 19 (2004) 1154-1164
    • (2004) J. Bone Miner. Res. , vol.19 , pp. 1154-1164
    • Kurihara, N.1    Reddy, S.V.2    Araki, N.3    Ishizuka, S.4    Ozono, K.5    Cornish, J.6
  • 49
    • 0034104393 scopus 로고    scopus 로고
    • Osteoclasts expressing the measles virus nucleocapsid gene display a pagetic phenotype
    • Kurihara N., Reddy S.V., Menaa C., Anderson D., and Roodman G.D. Osteoclasts expressing the measles virus nucleocapsid gene display a pagetic phenotype. J. Clin. Invest. 105 (2000) 607-614
    • (2000) J. Clin. Invest. , vol.105 , pp. 607-614
    • Kurihara, N.1    Reddy, S.V.2    Menaa, C.3    Anderson, D.4    Roodman, G.D.5
  • 52
    • 0036094026 scopus 로고    scopus 로고
    • Recurrent mutation of the gene encoding sequestosome 1 (SQSTM1/p62) in Paget disease of bone
    • Laurin N., Brown J.P., Morissette J., and Raymond V. Recurrent mutation of the gene encoding sequestosome 1 (SQSTM1/p62) in Paget disease of bone. Am. J. Hum. Genet. 70 (2002) 1582-1588
    • (2002) Am. J. Hum. Genet. , vol.70 , pp. 1582-1588
    • Laurin, N.1    Brown, J.P.2    Morissette, J.3    Raymond, V.4
  • 54
    • 37549034220 scopus 로고    scopus 로고
    • Identification of a major locus for Paget disease on chromosome 10p13 in families of British descent
    • Lucas G., Riches P., Hocking L., Cundy T., Nicholson G., Walsh J., et al. Identification of a major locus for Paget disease on chromosome 10p13 in families of British descent. J. Bone Miner. Res. 23 (2008) 58-63
    • (2008) J. Bone Miner. Res. , vol.23 , pp. 58-63
    • Lucas, G.1    Riches, P.2    Hocking, L.3    Cundy, T.4    Nicholson, G.5    Walsh, J.6
  • 55
    • 34247874843 scopus 로고    scopus 로고
    • Contribution of genetic factors to the pathogenesis of Paget's disease of bone and related disorders
    • Lucas G.J., Daroszewska A., and Ralston S.H. Contribution of genetic factors to the pathogenesis of Paget's disease of bone and related disorders. J. Bone Miner. Res. 21 Suppl 2 (2006) 31-37
    • (2006) J. Bone Miner. Res. , vol.21 , Issue.SUPPL. 2 , pp. 31-37
    • Lucas, G.J.1    Daroszewska, A.2    Ralston, S.H.3
  • 56
    • 31544436590 scopus 로고    scopus 로고
    • Evaluation of the role of Valosin-containing protein in the pathogenesis of familial and sporadic Paget's disease of bone
    • Lucas G.J., Mehta S.G., Hocking L.J., Stewart T.L., Cundy T., Nicholson G.C., et al. Evaluation of the role of Valosin-containing protein in the pathogenesis of familial and sporadic Paget's disease of bone. Bone 38 (2006) 280-285
    • (2006) Bone , vol.38 , pp. 280-285
    • Lucas, G.J.1    Mehta, S.G.2    Hocking, L.J.3    Stewart, T.L.4    Cundy, T.5    Nicholson, G.C.6
  • 58
    • 33845967453 scopus 로고    scopus 로고
    • Serum OPG and RANKL levels before and after intravenous bisphosphonate treatment in Paget's disease of bone
    • Martini G., Gennari L., Merlotti D., Salvadori S., Franci M.B., Campagna S., et al. Serum OPG and RANKL levels before and after intravenous bisphosphonate treatment in Paget's disease of bone. Bone 40 (2007) 457-463
    • (2007) Bone , vol.40 , pp. 457-463
    • Martini, G.1    Gennari, L.2    Merlotti, D.3    Salvadori, S.4    Franci, M.B.5    Campagna, S.6
  • 60
    • 0022631521 scopus 로고
    • Filamentous structures morphologically similar to viral nucleocapsids in otosclerotic lesions in two patients
    • McKenna M.J., Mills B.G., Galey F.R., and Linthicum Jr. F.H. Filamentous structures morphologically similar to viral nucleocapsids in otosclerotic lesions in two patients. Am. J. Otol. 7 (1986) 25-28
    • (1986) Am. J. Otol. , vol.7 , pp. 25-28
    • McKenna, M.J.1    Mills, B.G.2    Galey, F.R.3    Linthicum Jr., F.H.4
  • 61
    • 0032146198 scopus 로고    scopus 로고
    • Detection of canine distemper virus in 100% of Paget's disease samples by in situ-reverse transcriptase polymerase chain reaction
    • Mee A.P., Dixon J.A., Hoyland J.A., Davies M., Selby P.L., and Mawer E.B. Detection of canine distemper virus in 100% of Paget's disease samples by in situ-reverse transcriptase polymerase chain reaction. Bone 23 (1998) 171-175
    • (1998) Bone , vol.23 , pp. 171-175
    • Mee, A.P.1    Dixon, J.A.2    Hoyland, J.A.3    Davies, M.4    Selby, P.L.5    Mawer, E.B.6
  • 62
    • 0029116734 scopus 로고
    • Generation of multinucleated osteoclast-like cells from canine bone marrow: effects of canine distemper virus
    • Mee A.P., May C., Bennett D., and Sharpe P.T. Generation of multinucleated osteoclast-like cells from canine bone marrow: effects of canine distemper virus. Bone 17 (1995) 47-55
    • (1995) Bone , vol.17 , pp. 47-55
    • Mee, A.P.1    May, C.2    Bennett, D.3    Sharpe, P.T.4
  • 63
    • 0033932526 scopus 로고    scopus 로고
    • Enhanced RANK ligand expression and responsivity of bone marrow cells in Paget's disease of bone
    • Menaa C., Reddy S.V., Kurihara N., Maeda H., Anderson D., Cundy T., et al. Enhanced RANK ligand expression and responsivity of bone marrow cells in Paget's disease of bone. J. Clin. Invest. 105 (2000) 1833-1838
    • (2000) J. Clin. Invest. , vol.105 , pp. 1833-1838
    • Menaa, C.1    Reddy, S.V.2    Kurihara, N.3    Maeda, H.4    Anderson, D.5    Cundy, T.6
  • 64
    • 0018968492 scopus 로고
    • Bone histomorphometry in Paget's disease. Quantitative and dynamic analysis of pagetic and nonpagetic bone tissue.
    • Meunier P.J., Coindre J.M., Edouard C.M., and Arlot M.E. Bone histomorphometry in Paget's disease. Quantitative and dynamic analysis of pagetic and nonpagetic bone tissue. Arthritis Rheum. 23 (1980) 1095-1103
    • (1980) Arthritis Rheum. , vol.23 , pp. 1095-1103
    • Meunier, P.J.1    Coindre, J.M.2    Edouard, C.M.3    Arlot, M.E.4
  • 65
    • 0028283338 scopus 로고
    • Multinucleated cells formed in vitro from Paget's bone marrow express viral antigens
    • Mills B.G., Frausto A., Singer F.R., Ohsaki Y., Demulder A., and Roodman G.D. Multinucleated cells formed in vitro from Paget's bone marrow express viral antigens. Bone 15 (1994) 443-448
    • (1994) Bone , vol.15 , pp. 443-448
    • Mills, B.G.1    Frausto, A.2    Singer, F.R.3    Ohsaki, Y.4    Demulder, A.5    Roodman, G.D.6
  • 66
    • 0017114175 scopus 로고
    • Nuclear inclusions in Paget's disease of bone
    • Mills B.G., and Singer F.R. Nuclear inclusions in Paget's disease of bone. Science 194 (1976) 201-202
    • (1976) Science , vol.194 , pp. 201-202
    • Mills, B.G.1    Singer, F.R.2
  • 67
    • 0019508461 scopus 로고
    • Immunohistological demonstration of respiratory syncytial virus antigens in Paget's disease of bone
    • Mills B.G., Singer F.R., Weiner L.P., and Holst P.A. Immunohistological demonstration of respiratory syncytial virus antigens in Paget's disease of bone. Proc. Natl. Acad. Sci. U. S. A. 78 (1981) 1209-1212
    • (1981) Proc. Natl. Acad. Sci. U. S. A. , vol.78 , pp. 1209-1212
    • Mills, B.G.1    Singer, F.R.2    Weiner, L.P.3    Holst, P.A.4
  • 68
    • 0021337486 scopus 로고
    • Evidence for both respiratory syncytial virus and measles virus antigens in the osteoclasts of patients with Paget's disease of bone
    • Mills B.G., Singer F.R., Weiner L.P., Suffin S.C., Stabile E., and Holst P. Evidence for both respiratory syncytial virus and measles virus antigens in the osteoclasts of patients with Paget's disease of bone. Clin. Orthop. Rel. Res. 183 (1984) 303-311
    • (1984) Clin. Orthop. Rel. Res. , vol.183 , pp. 303-311
    • Mills, B.G.1    Singer, F.R.2    Weiner, L.P.3    Suffin, S.C.4    Stabile, E.5    Holst, P.6
  • 69
    • 0023787752 scopus 로고
    • Osteoclasts in human osteopetrosis contain viral-nucleocapsid-like nuclear inclusions
    • Mills B.G., Yabe H., and Singer F.R. Osteoclasts in human osteopetrosis contain viral-nucleocapsid-like nuclear inclusions. J. Bone Miner. Res. 3 (1988) 101-106
    • (1988) J. Bone Miner. Res. , vol.3 , pp. 101-106
    • Mills, B.G.1    Yabe, H.2    Singer, F.R.3
  • 70
    • 0013515410 scopus 로고
    • Paget's disease (osteitis deformans) and hereditary
    • Montagu M. Paget's disease (osteitis deformans) and hereditary. Am. J. Hum. Genet. 1 (1949) 94-95
    • (1949) Am. J. Hum. Genet. , vol.1 , pp. 94-95
    • Montagu, M.1
  • 72
    • 0036375921 scopus 로고    scopus 로고
    • The atypical PKC scaffold protein P62 is a novel target for anti-inflammatory and anti-cancer therapies
    • Moscat J., and Diaz-Meco M.T. The atypical PKC scaffold protein P62 is a novel target for anti-inflammatory and anti-cancer therapies. Adv. Enzyme Regul. 42 (2002) 173-179
    • (2002) Adv. Enzyme Regul. , vol.42 , pp. 173-179
    • Moscat, J.1    Diaz-Meco, M.T.2
  • 73
    • 15544379426 scopus 로고    scopus 로고
    • Interleukin-6 and osteoprotegerin systems in Paget's disease of bone: relationship to risedronate treatment
    • Mossetti G., Rendina D., De F.G., Viceconti R., Di D.G., Cioffi M., et al. Interleukin-6 and osteoprotegerin systems in Paget's disease of bone: relationship to risedronate treatment. Bone 36 (2005) 549-554
    • (2005) Bone , vol.36 , pp. 549-554
    • Mossetti, G.1    Rendina, D.2    De, F.G.3    Viceconti, R.4    Di, D.G.5    Cioffi, M.6
  • 74
    • 38549119003 scopus 로고    scopus 로고
    • Gene expression profiling in Paget's disease of bone: upregulation of interferon signaling pathways in pagetic monocytes and lymphocytes
    • Nagy Z.B., Gergely P., Donath J., Borgulya G., Csanad M., and Poor G. Gene expression profiling in Paget's disease of bone: upregulation of interferon signaling pathways in pagetic monocytes and lymphocytes. J. Bone Miner. Res. 23 (2008) 253-259
    • (2008) J. Bone Miner. Res. , vol.23 , pp. 253-259
    • Nagy, Z.B.1    Gergely, P.2    Donath, J.3    Borgulya, G.4    Csanad, M.5    Poor, G.6
  • 75
    • 0038643034 scopus 로고    scopus 로고
    • Phenotypic characterization of early onset Paget's disease of bone caused by a 27-bp duplication in the TNFRSF11A gene
    • Nakatsuka K., Nishizawa Y., and Ralston S.H. Phenotypic characterization of early onset Paget's disease of bone caused by a 27-bp duplication in the TNFRSF11A gene. J. Bone Miner. Res. 18 (2003) 1381-1385
    • (2003) J. Bone Miner. Res. , vol.18 , pp. 1381-1385
    • Nakatsuka, K.1    Nishizawa, Y.2    Ralston, S.H.3
  • 76
    • 33846505388 scopus 로고    scopus 로고
    • Differential gene expression in cultured osteoblasts and bone marrow stromal cells from patients with Paget's disease of bone
    • Naot D., Bava U., Matthews B., Callon K.E., Gamble G.D., Black M., et al. Differential gene expression in cultured osteoblasts and bone marrow stromal cells from patients with Paget's disease of bone. J. Bone Miner. Res. 22 (2007) 298-309
    • (2007) J. Bone Miner. Res. , vol.22 , pp. 298-309
    • Naot, D.1    Bava, U.2    Matthews, B.3    Callon, K.E.4    Gamble, G.D.5    Black, M.6
  • 77
    • 0030895661 scopus 로고    scopus 로고
    • Cellular immunity aspects in elderly subjects with Paget's disease of bone
    • Natale V.M., Filho W.J., and Duarte A.J. Cellular immunity aspects in elderly subjects with Paget's disease of bone. Calcif. Tissue Int. 60 (1997) 410-414
    • (1997) Calcif. Tissue Int. , vol.60 , pp. 410-414
    • Natale, V.M.1    Filho, W.J.2    Duarte, A.J.3
  • 78
    • 0033827136 scopus 로고    scopus 로고
    • Osteoclast differentiation from circulating mononuclear precursors in Paget's disease is hypersensitive to 1,25-dihydroxyvitamin D(3) and RANKL
    • Neale S.D., Smith R., Wass J.A., and Athanasou N.A. Osteoclast differentiation from circulating mononuclear precursors in Paget's disease is hypersensitive to 1,25-dihydroxyvitamin D(3) and RANKL. Bone 27 (2000) 409-416
    • (2000) Bone , vol.27 , pp. 409-416
    • Neale, S.D.1    Smith, R.2    Wass, J.A.3    Athanasou, N.A.4
  • 80
    • 0022414463 scopus 로고
    • Past pets and Paget's disease
    • O'Driscoll J.B., and Anderson D.C. Past pets and Paget's disease. Lancet 2 (1985) 919-921
    • (1985) Lancet , vol.2 , pp. 919-921
    • O'Driscoll, J.B.1    Anderson, D.C.2
  • 81
    • 0033831096 scopus 로고    scopus 로고
    • Absence of measles virus and canine distemper virus transcripts in long-term bone marrow cultures from patients with Paget's disease of bone
    • Ooi C.G., Walsh C.A., Gallagher J.A., and Fraser W.D. Absence of measles virus and canine distemper virus transcripts in long-term bone marrow cultures from patients with Paget's disease of bone. Bone 27 (2000) 417-421
    • (2000) Bone , vol.27 , pp. 417-421
    • Ooi, C.G.1    Walsh, C.A.2    Gallagher, J.A.3    Fraser, W.D.4
  • 83
    • 34249704670 scopus 로고    scopus 로고
    • Multicenter blinded analysis of RT-PCR detection methods for paramyxoviruses in relation to Paget's disease of bone
    • Ralston S.H., Afzal M.A., Helfrich M.H., Fraser W.D., Gallagher J.A., Mee A., et al. Multicenter blinded analysis of RT-PCR detection methods for paramyxoviruses in relation to Paget's disease of bone. J. Bone Miner. Res. 22 (2007) 569-577
    • (2007) J. Bone Miner. Res. , vol.22 , pp. 569-577
    • Ralston, S.H.1    Afzal, M.A.2    Helfrich, M.H.3    Fraser, W.D.4    Gallagher, J.A.5    Mee, A.6
  • 84
    • 0025720792 scopus 로고
    • Failure to detect paramyxovirus sequences in Paget's disease of bone using the polymerase chain reaction
    • Ralston S.H., DiGiovine F.S., Gallacher S.J., Boyle I.T., and Duff G.W. Failure to detect paramyxovirus sequences in Paget's disease of bone using the polymerase chain reaction. J. Bone Miner. Res. 6 (1991) 1243-1248
    • (1991) J. Bone Miner. Res. , vol.6 , pp. 1243-1248
    • Ralston, S.H.1    DiGiovine, F.S.2    Gallacher, S.J.3    Boyle, I.T.4    Duff, G.W.5
  • 85
    • 0028358344 scopus 로고
    • Cytokine and growth factor expression in Paget's disease: analysis by reverse-transcription/polymerase chain reaction
    • Ralston S.H., Hoey S.A., Gallacher S.J., Adamson B.B., and Boyle I.T. Cytokine and growth factor expression in Paget's disease: analysis by reverse-transcription/polymerase chain reaction. Br. J. Rheumatol. 33 (1994) 620-625
    • (1994) Br. J. Rheumatol. , vol.33 , pp. 620-625
    • Ralston, S.H.1    Hoey, S.A.2    Gallacher, S.J.3    Adamson, B.B.4    Boyle, I.T.5
  • 86
    • 33745510646 scopus 로고    scopus 로고
    • A novel mutation (K378X) in the sequestosome 1 gene associated with increased NF-kappaB signaling and Paget's disease of bone with a severe phenotype
    • Rea S.L., Walsh J.P., Ward L., Yip K., Ward B.K., Kent G.N., et al. A novel mutation (K378X) in the sequestosome 1 gene associated with increased NF-kappaB signaling and Paget's disease of bone with a severe phenotype. J. Bone Miner. Res. 21 (2006) 1136-1145
    • (2006) J. Bone Miner. Res. , vol.21 , pp. 1136-1145
    • Rea, S.L.1    Walsh, J.P.2    Ward, L.3    Yip, K.4    Ward, B.K.5    Kent, G.N.6
  • 89
    • 0016318811 scopus 로고
    • Particularites ultrastructurales des osteoclasts de la maladie de Paget
    • Rebel A., Malkani K., Basle M., and Bregeon C. Particularites ultrastructurales des osteoclasts de la maladie de Paget. Rev. Rhum. Mal. Osteoartic 41 (1974) 767-771
    • (1974) Rev. Rhum. Mal. Osteoartic , vol.41 , pp. 767-771
    • Rebel, A.1    Malkani, K.2    Basle, M.3    Bregeon, C.4
  • 90
    • 0034989963 scopus 로고    scopus 로고
    • Osteoclasts formed by measles virus-infected osteoclast precursors from hCD46 transgenic mice express characteristics of pagetic osteoclasts
    • Reddy S.V., Kurihara N., Menaa C., Landucci G., Forthal D., Koop B.A., et al. Osteoclasts formed by measles virus-infected osteoclast precursors from hCD46 transgenic mice express characteristics of pagetic osteoclasts. Endocrinology 142 (2001) 2898-2905
    • (2001) Endocrinology , vol.142 , pp. 2898-2905
    • Reddy, S.V.1    Kurihara, N.2    Menaa, C.3    Landucci, G.4    Forthal, D.5    Koop, B.A.6
  • 91
    • 0032883330 scopus 로고    scopus 로고
    • Measles virus nucleocapsid transcript expression is not restricted to the osteoclast lineage in patients with Paget's disease of bone
    • Reddy S.V., Menaa C., Singer F.R., Cundy T., Cornish J., Whyte M.P., et al. Measles virus nucleocapsid transcript expression is not restricted to the osteoclast lineage in patients with Paget's disease of bone. Exp. Hematol. 27 (1999) 1528-1532
    • (1999) Exp. Hematol. , vol.27 , pp. 1528-1532
    • Reddy, S.V.1    Menaa, C.2    Singer, F.R.3    Cundy, T.4    Cornish, J.5    Whyte, M.P.6
  • 92
    • 33845225616 scopus 로고    scopus 로고
    • Evidence for increased clinical severity of familial and sporadic Paget's disease of bone in Campania, southern Italy
    • Rendina D., Gennari L., De F.G., Merlotti D., de C.E., Fazioli F., et al. Evidence for increased clinical severity of familial and sporadic Paget's disease of bone in Campania, southern Italy. J. Bone Miner. Res. 21 (2006) 1828-1835
    • (2006) J. Bone Miner. Res. , vol.21 , pp. 1828-1835
    • Rendina, D.1    Gennari, L.2    De, F.G.3    Merlotti, D.4    de, C.E.5    Fazioli, F.6
  • 95
    • 37549055893 scopus 로고    scopus 로고
    • Mice with a truncation mutation affecting sequestosome 1 exhibit several phenotypic features in common with Paget's disease of bone
    • Rojas J.A., Daroszewska A., Helfrich M., Layfield R., van't Hof R., and Ralston S.H. Mice with a truncation mutation affecting sequestosome 1 exhibit several phenotypic features in common with Paget's disease of bone. Calcif. Tiss. Int. 81 (2007) 149
    • (2007) Calcif. Tiss. Int. , vol.81 , pp. 149
    • Rojas, J.A.1    Daroszewska, A.2    Helfrich, M.3    Layfield, R.4    van't Hof, R.5    Ralston, S.H.6
  • 97
    • 0027359196 scopus 로고
    • Mice transgenic for HTLV-I LTR-tax exhibit tax expression in bone, skeletal alterations, and high bone turnover
    • Ruddle N.H., Li C.B., Horne W.C., Santiago P., Troiano N., Jay G., et al. Mice transgenic for HTLV-I LTR-tax exhibit tax expression in bone, skeletal alterations, and high bone turnover. Virology 197 (1993) 196-204
    • (1993) Virology , vol.197 , pp. 196-204
    • Ruddle, N.H.1    Li, C.B.2    Horne, W.C.3    Santiago, P.4    Troiano, N.5    Jay, G.6
  • 98
    • 4444220680 scopus 로고    scopus 로고
    • Sequestosome 1/p62 is a polyubiquitin chain binding protein involved in ubiquitin proteasome degradation
    • Seibenhener M.L., Babu J.R., Geetha T., Wong H.C., Krishna N.R., and Wooten M.W. Sequestosome 1/p62 is a polyubiquitin chain binding protein involved in ubiquitin proteasome degradation. Mol. Cell. Biol. 24 (2004) 8055-8068
    • (2004) Mol. Cell. Biol. , vol.24 , pp. 8055-8068
    • Seibenhener, M.L.1    Babu, J.R.2    Geetha, T.3    Wong, H.C.4    Krishna, N.R.5    Wooten, M.W.6
  • 99
    • 0025282325 scopus 로고
    • Paget's disease of bone and previous pet ownership in the United States: dogs exonerated
    • Siris E.S., Kelsey J.L., Flaster E., and Parker S. Paget's disease of bone and previous pet ownership in the United States: dogs exonerated. Int.J Epidemiol. 19 (1990) 455-458
    • (1990) Int.J Epidemiol. , vol.19 , pp. 455-458
    • Siris, E.S.1    Kelsey, J.L.2    Flaster, E.3    Parker, S.4
  • 102
    • 33645987648 scopus 로고    scopus 로고
    • Bone stromal cells in pagetic bone and Paget's sarcoma express RANKL and support human osteoclast formation
    • Sun S.G., Lau Y.S., Itonaga I., Sabokbar A., and Athanasou N.A. Bone stromal cells in pagetic bone and Paget's sarcoma express RANKL and support human osteoclast formation. J. Pathol. 209 (2006) 114-120
    • (2006) J. Pathol. , vol.209 , pp. 114-120
    • Sun, S.G.1    Lau, Y.S.2    Itonaga, I.3    Sabokbar, A.4    Athanasou, N.A.5
  • 104
    • 0037129205 scopus 로고    scopus 로고
    • RANKL maintains bone homeostasis through c-Fos-dependent induction of interferon-beta
    • Takayanagi H., Kim S., Matsuo K., Suzuki H., Suzuki T., Sato K., et al. RANKL maintains bone homeostasis through c-Fos-dependent induction of interferon-beta. Nature 416 (2002) 744-749
    • (2002) Nature , vol.416 , pp. 744-749
    • Takayanagi, H.1    Kim, S.2    Matsuo, K.3    Suzuki, H.4    Suzuki, T.5    Sato, K.6
  • 105
    • 0033827275 scopus 로고    scopus 로고
    • Long-term trends in the incidence of Paget's disease of bone
    • Tiegs R.D., Lohse C.M., Wollan P.C., and Melton L.J. Long-term trends in the incidence of Paget's disease of bone. Bone 27 (2000) 423-427
    • (2000) Bone , vol.27 , pp. 423-427
    • Tiegs, R.D.1    Lohse, C.M.2    Wollan, P.C.3    Melton, L.J.4
  • 108
    • 1842483843 scopus 로고    scopus 로고
    • Inclusion body myopathy associated with Paget disease of bone and frontotemporal dementia is caused by mutant valosin-containing protein
    • Watts G.D., Wymer J., Kovach M.J., Mehta S.G., Mumm S., Darvish D., et al. Inclusion body myopathy associated with Paget disease of bone and frontotemporal dementia is caused by mutant valosin-containing protein. Nat. Genet. 36 (2004) 377-381
    • (2004) Nat. Genet. , vol.36 , pp. 377-381
    • Watts, G.D.1    Wymer, J.2    Kovach, M.J.3    Mehta, S.G.4    Mumm, S.5    Darvish, D.6
  • 109
    • 31144470450 scopus 로고    scopus 로고
    • Inclusion body myopathy-associated mutations in p97/VCP impair endoplasmic reticulum-associated degradation
    • Weihl C.C., Dalal S., Pestronk A., and Hanson P.I. Inclusion body myopathy-associated mutations in p97/VCP impair endoplasmic reticulum-associated degradation. Hum. Mol. Genet. 15 (2006) 189-199
    • (2006) Hum. Mol. Genet. , vol.15 , pp. 189-199
    • Weihl, C.C.1    Dalal, S.2    Pestronk, A.3    Hanson, P.I.4
  • 110
    • 0036133351 scopus 로고    scopus 로고
    • Expansile skeletal hyperphosphatasia is caused by a 15-base pair tandem duplication in TNFRSF11A encoding RANK and is allelic to familial expansile osteolysis
    • Whyte M.P., and Hughes A.E. Expansile skeletal hyperphosphatasia is caused by a 15-base pair tandem duplication in TNFRSF11A encoding RANK and is allelic to familial expansile osteolysis. J. Bone Miner. Res. 17 (2002) 26-29
    • (2002) J. Bone Miner. Res. , vol.17 , pp. 26-29
    • Whyte, M.P.1    Hughes, A.E.2
  • 114
    • 33746644136 scopus 로고    scopus 로고
    • p62 ubiquitin binding-associated domain mediated the receptor activator of nuclear factor-kappaB ligand-induced osteoclast formation: a new insight into the pathogenesis of Paget's disease of bone
    • Yip K.H., Feng H., Pavlos N.J., Zheng M.H., and Xu J. p62 ubiquitin binding-associated domain mediated the receptor activator of nuclear factor-kappaB ligand-induced osteoclast formation: a new insight into the pathogenesis of Paget's disease of bone. Am. J. Pathol. 169 (2006) 503-514
    • (2006) Am. J. Pathol. , vol.169 , pp. 503-514
    • Yip, K.H.1    Feng, H.2    Pavlos, N.J.3    Zheng, M.H.4    Xu, J.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.