Osteoclasts expressing the measles virus nucleocapsid gene display a pagetic phenotype

Journal of Clinical Investigation

Volumn 105, Issue 5, 2000, Pages 607-614

  Kurihara, Noriyoshi ^a   Reddy, Sakamuri V ^a   Menaa, Cheikh ^a   Anderson, Dirk ^b   Roodman, G David ^a,c,d  

^a UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^b AMGEN INC   (United States)

^c VETERANS AFFAIRS MEDICAL CENTER   (United States)

^d SOUTH TEXAS VETERANS HEALTH CARE SYSTEM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; DISEASE ASSOCIATION; GENE EXPRESSION; HUMAN; HUMAN CELL; MEASLES VIRUS; OSTEOCLAST; PAGET BONE DISEASE; PATHOPHYSIOLOGY; PRIORITY JOURNAL; VIRUS NUCLEOCAPSID;

EID: 0034104393     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI8489     Document Type: Article

References (27)

1. Hosking, D.J. 1981. Paget's disease of bone. Br. Med. J. (Clin. Res. Ed.). 283:686-688.
2. Yates, A.J.P. 1988. Paget's disease of bone. Baillieres Clin. Endocrinol. Metab. 2:267-295.
3. Kukita, A., Chenu, C., McManus, L.M., Mundy, G.R. and Roodman, G.D. 1990. Atypical multinucleated cells form in long-term marrow cultures from patients with Paget's disease. J. Clin. Invest. 85:1280-1286.
4. Mills, B.G., et al. 1984. Evidence for both respiratory syncytial virus and measles virus antigens in the osteoclasts of patients with Paget's disease of bone. Clin. Orthop. Relat. Res. 183:303-311.
5. Basle, M.F., et al. 1985. Paramyxovirus antigens in osteoclasts from Paget's bone tissue detected by monoclonal antibodies. J. Gen. Virol. 66:2103-2110.
6. Gordon, M.T., Mee, A.P., Anderson, D.C., and Sharpe, P.T. 1995. Canine bone marrow cultures infected with canine distemper virus: an in vitro model of Paget's disease. Bone. 19:461S-466S.
7. Mills, B.G., Singer, F.R., Weiner, L.P., and Holst, P A. 1981. Immunohistochemical demonstration of respiratory syncytial virus antigens in Paget's disease of bone. Proc. Natl. Acad. Sci. USA. 78:1209-1213.
8. Basle, M.F., Fournier, J.G., Rozenblatt, S., Rebel, A., and Bouteille, M. 1986. Measles virus RNA detected in Paget's disease bone tissue by in situ hybridization. J. Gen. Virol. 67:907-913.
9. Gordon, M.T., Anderson, D.C., and Sharpe, P.T. 1991. Canine distemper virus localized in bone cells of patients with Paget's disease. Bone. 12:195-201.
10. Reddy, S.V., Singer, F.R., Mallette, L., and Roodman, G.D. 1996. Detection of measles virus nucleocapsid transcripts in circulating blood cells and hematopoietic progenitors from patients with Paget's disease. J. Bone Miner. Res. 11:1602-1607.
11. Kurihara, N., Chenu, C., Miller, M., Civin, C.I., and Roodman, G.D. 1990. Identification of committed mononuclear precursors for osteoclast-like cells formed in long-term marrow cultures. Endocrinology. 126:2733-2741.
12. Graham, F.L., and van der Eb, A.J. 1973. A new technique for the assay of infectivity or human adenovirus 5 DNA. Virology. 52:456-467.
13. Miller, A.D., and Buttimore, C. 1986. Redesign of retrovirus packaging cell lines to avoid recombination leading to helper virus production. Mol. Cell. Biol. 6:2895-2902.
14. Ausubel, F.M., et al. 1994. Current protocols in molecular biology. Volume 9. John Wiley & Sons, New York, NY. 4-9.
15. Dignam, J.D., Lebovitz, R.M., and Roeder, R.G. 1983. Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res. 11:1475-1489.
16. 3 24-hydroxylase gene. J. Biol. Chem. 269:10545-10550.
17. Yasuda, H., et al. 1998. Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKL. Proc. Natl. Acad. Sci. USA. 95:3597-3602.
18. Capparelli, C., et al. 1998. Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation. Cell. 93:165-176.
19. Roodman, G.D., et al. 1992. Interleukin-6: a potential autocrine/paracrine factor in Paget's disease of bone. J. Clin. Invest. 89:46-52.
20. Hoyland, J.A., Freemont, A.J., and Sharpe, P.T. 1994. Interleukin-6, IL-6 receptor, and IL-6 nuclear factor gene expression in Paget's disease. J. Bone Miner. Res. 9:75-80.
21. Anderson, D.M., et al. 1997. A homologue of the TNF receptor and its ligand enhance T-cell growth and dendritic-cell function. Nature. 390:175-179.
22. Kurihara, N., Bertolini, D., Suda, T., Akiyama, Y., and Roodman, G.D. 1990. IL-6 stimulates osteoclast-like multinucleated cell formation in long-term human marrow cultures by inducing IL-1 release. J. Immunol. 144:4226-4230.
23. De La Mata, J., et al. 1995. IL-6 enhances hypercalcemia and bone resorption mediated by PTH-rP in vivo. J. Clin. Invest. 95:2846-2852.
24. Karp, C.L., et al. 1996. Mechanism of suppression of cell-mediated immunity by measles virus. Science. 273:228-231.
25. Demulder, A., Takahashi, S., Singer, F.R., Hosking, D.J., and Roodman, G.D. 1993. Evidence for abnormalities in osteoclast precursors and the marrow microenvironment in Pager's disease. Endocrinology. 133:1978-1982.
26. 3 hypersensitivity of osteoclast precursors from patients with Pager's disease. J. Bone Miner. Res. In press.
27. Liston, P., Batal, R., DiFlumeri, C., and Briedis, D.J. 1997. Protein interaction domains of the measles virus nucleocapsid protein. Arch. Virol. 142:305-321.