Rifampicin does not significantly affect the expression of small heterodimer partner in primary human hepatocytes

Frontiers in Pharmacology

Volumn 3 JAN, Issue , 2012, Pages

  Pavek, Petr ^a   Stejskalova, Lucie ^a,b   Krausova, Lucie ^a   Bitman, Michal ^a   Vrzal, Radim ^b   Dvorak, Zdenek ^b  

^a Charles University in Prague Faculty of Pharmacy   (Czech Republic)

^b PALACKÝ UNIVERSITY   (Czech Republic)

Author keywords

CYP3A4; Cytochrome P450; Induction; PXR; SHP

Indexed keywords

COREPRESSOR PROTEIN; CYTOCHROME P450 3A4; MESSENGER RNA; PREGNANE X RECEPTOR; RIFAMPICIN; SMALL HETERODIMER PARTNER PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOWN REGULATION; DRUG MECHANISM; GENE EXPRESSION REGULATION; GENE INDUCTION; GENE TARGETING; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; INCUBATION TIME; LIVER CELL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; REPORTER GENE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TRANSACTIVATION;

EID: 84865987428     PISSN: None     EISSN: 16639812     Source Type: Journal    
DOI: 10.3389/fphar.2012.00001     Document Type: Article

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