메뉴 건너뛰기




Volumn 13, Issue 11, 2012, Pages 1018-1025

Interferon-gamma enhances radiation-induced cell death via downregulation of Chk1

Author keywords

Cancer cell death; Chk1; IFN ; Ionizing radiation; Radiosensitization; XAF1

Indexed keywords

CHECKPOINT KINASE 1; GAMMA INTERFERON; PROTEIN P53; SMALL INTERFERING RNA; X LINKED INHIBITOR OF APOPTOSIS;

EID: 84865843204     PISSN: 15384047     EISSN: 15558576     Source Type: Journal    
DOI: 10.4161/cbt.20990     Document Type: Article
Times cited : (10)

References (36)
  • 1
    • 9644262469 scopus 로고    scopus 로고
    • Interferons, interferon-like cytokines, and their receptors
    • PMID:15546383
    • Pestka S, Krause CD, Walter MR. Interferons, interferon-like cytokines, and their receptors. Immunol Rev 2004; 202:8-32; PMID:15546383; http://dx.doi.org/10.1111/j.0105-2896.2004.00204.x.
    • (2004) Immunol Rev , vol.202 , pp. 8-32
    • Pestka, S.1    Krause, C.D.2    Walter, M.R.3
  • 2
    • 27744456908 scopus 로고    scopus 로고
    • Gamma interferon: A central mediator in atherosclerosis
    • PMID:16283107
    • Leon ML, Zuckerman SH. Gamma interferon: a central mediator in atherosclerosis. Inflamm Res 2005; 54:395-411; PMID:16283107; http://dx.doi.org/10.1007/s00011-005-1377-2.
    • (2005) Inflamm Res , vol.54 , pp. 395-411
    • Leon, M.L.1    Zuckerman, S.H.2
  • 3
    • 0037790592 scopus 로고    scopus 로고
    • Apoptosis and interferons: Role of interferon-stimulated genes as mediators of apoptosis
    • PMID:12766484
    • Chawla-Sarkar M, Lindner DJ, Liu YF, Williams BR, Sen GC, Silverman RH, et al. Apoptosis and interferons: role of interferon-stimulated genes as mediators of apoptosis. Apoptosis 2003; 8:237-49; PMID:12766484; http://dx.doi.org/10.1023/A:1023668705040.
    • (2003) Apoptosis , vol.8 , pp. 237-249
    • Chawla-Sarkar, M.1    Lindner, D.J.2    Liu, Y.F.3    Williams, B.R.4    Sen, G.C.5    Silverman, R.H.6
  • 4
    • 0034895641 scopus 로고    scopus 로고
    • Preferential induction of apoptosis by interferon (IFN) beta compared with IFN-alpha2: Correlation with TRAIL/Apo2L induction in melanoma cell lines
    • PMID:11410525
    • Chawla-Sarkar M, Leaman DW, Borden EC. Preferential induction of apoptosis by interferon (IFN) beta compared with IFN-alpha2: correlation with TRAIL/Apo2L induction in melanoma cell lines. Clin Cancer Res 2001; 7:1821-31; PMID:11410525.
    • (2001) Clin Cancer Res , vol.7 , pp. 1821-1831
    • Chawla-Sarkar, M.1    Leaman, D.W.2    Borden, E.C.3
  • 5
    • 0035816638 scopus 로고    scopus 로고
    • Inositol hexakisphosphate kinase 2 mediates growth suppressive and apoptotic effects of interferon-beta in ovarian carcinoma cells
    • PMID:11337497
    • Morrison BH, Bauer JA, Kalvakolanu DV, Lindner DJ. Inositol hexakisphosphate kinase 2 mediates growth suppressive and apoptotic effects of interferon-beta in ovarian carcinoma cells. J Biol Chem 2001; 276:24965-70; PMID:11337497; http://dx.doi.org/10.1074/jbc.M101161200.
    • (2001) J Biol Chem , vol.276 , pp. 24965-24970
    • Morrison, B.H.1    Bauer, J.A.2    Kalvakolanu, D.V.3    Lindner, D.J.4
  • 6
    • 0030985893 scopus 로고    scopus 로고
    • Interferon-gamma modulates a p53-independent apoptotic pathway and apoptosis-related gene expression
    • PMID:9195941
    • Ossina NK, Cannas A, Powers VC, Fitzpatrick PA, Knight JD, Gilbert JR, et al. Interferon-gamma modulates a p53-independent apoptotic pathway and apoptosis-related gene expression. J Biol Chem 1997; 272:16351-7; PMID:9195941; http://dx.doi.org/10.1074/jbc.272.26.16351.
    • (1997) J Biol Chem , vol.272 , pp. 16351-16357
    • Ossina, N.K.1    Cannas, A.2    Powers, V.C.3    Fitzpatrick, P.A.4    Knight, J.D.5    Gilbert, J.R.6
  • 7
    • 0037461894 scopus 로고    scopus 로고
    • Interferon regulatory factor-1 (IRF-1) is a mediator for interferon-gamma induced attenuation of telomerase activity and human telomerase reverse transcriptase (hTERT) expression
    • PMID:12545159
    • Lee SH, Kim JW, Lee HW, Cho YS, Oh SH, Kim YJ, et al. Interferon regulatory factor-1 (IRF-1) is a mediator for interferon-gamma induced attenuation of telomerase activity and human telomerase reverse transcriptase (hTERT) expression. Oncogene 2003; 22:381-91; PMID:12545159; http://dx.doi.org/10.1038/sj.onc.1206133.
    • (2003) Oncogene , vol.22 , pp. 381-391
    • Lee, S.H.1    Kim, J.W.2    Lee, H.W.3    Cho, Y.S.4    Oh, S.H.5    Kim, Y.J.6
  • 8
    • 0842266786 scopus 로고    scopus 로고
    • Interferongamma: An overview of signals, mechanisms and functions
    • PMID:14525967
    • Schroder K, Hertzog PJ, Ravasi T, Hume DA. Interferongamma: an overview of signals, mechanisms and functions. J Leukoc Biol 2004; 75:163-89; PMID:14525967; http://dx.doi.org/10.1189/jlb.0603252.
    • (2004) J Leukoc Biol , vol.75 , pp. 163-189
    • Schroder, K.1    Hertzog, P.J.2    Ravasi, T.3    Hume, D.A.4
  • 9
    • 0029923780 scopus 로고    scopus 로고
    • Cell growth arrest and induction of cyclin-dependent kinase inhibitor p21 WAF1/CIP1 mediated by STAT1
    • PMID:8614832
    • Chin YE, Kitagawa M, Su WC, You ZH, Iwamoto Y, Fu XY. Cell growth arrest and induction of cyclin-dependent kinase inhibitor p21 WAF1/CIP1 mediated by STAT1. Science 1996; 272:719-22; PMID:8614832; http://dx.doi.org/10.1126/ science.272.5262.719.
    • (1996) Science , vol.272 , pp. 719-722
    • Chin, Y.E.1    Kitagawa, M.2    Su, W.C.3    You, Z.H.4    Iwamoto, Y.5    Fu, X.Y.6
  • 10
    • 34547821979 scopus 로고    scopus 로고
    • Involvement of oxidative and nitrosative stress in modulation of gene expression and functional responses by IFNgamma
    • PMID:17606979
    • Prasanna SJ, Saha B, Nandi D. Involvement of oxidative and nitrosative stress in modulation of gene expression and functional responses by IFNgamma. Int Immunol 2007; 19:867-79; PMID:17606979; http://dx.doi.org/10.1093/intimm/ dxm058.
    • (2007) Int Immunol , vol.19 , pp. 867-879
    • Prasanna, S.J.1    Saha, B.2    Nandi, D.3
  • 11
    • 59049088856 scopus 로고    scopus 로고
    • Interferongamma induces cellular senescence through p53-dependent DNA damage signaling in human endothelial cells
    • PMID:19071156
    • Kim KS, Kang KW, Seu YB, Baek SH, Kim JR. Interferongamma induces cellular senescence through p53-dependent DNA damage signaling in human endothelial cells. Mech Ageing Dev 2009; 130:179-88; PMID:19071156; http://dx.doi.org/10.1016/j.mad.2008.11.004.
    • (2009) Mech Ageing Dev , vol.130 , pp. 179-188
    • Kim, K.S.1    Kang, K.W.2    Seu, Y.B.3    Baek, S.H.4    Kim, J.R.5
  • 12
  • 13
    • 24044476837 scopus 로고    scopus 로고
    • Genotoxic stress targets human Chk1 for degradation by the ubiquitin-proteasome pathway
    • PMID:16137618
    • Zhang YW, Otterness DM, Chiang GG, Xie W, Liu YC, Mercurio F, et al. Genotoxic stress targets human Chk1 for degradation by the ubiquitin-proteasome pathway. Mol Cell 2005; 19:607-18; PMID:16137618; http://dx.doi.org/10.1016/j. molcel.2005.07.019.
    • (2005) Mol Cell , vol.19 , pp. 607-618
    • Zhang, Y.W.1    Otterness, D.M.2    Chiang, G.G.3    Xie, W.4    Liu, Y.C.5    Mercurio, F.6
  • 14
    • 58549089689 scopus 로고    scopus 로고
    • Essential function of Chk1 can be uncoupled from DNA damage checkpoint and replication control
    • PMID:19091954
    • Wilsker D, Petermann E, Helleday T, Bunz F. Essential function of Chk1 can be uncoupled from DNA damage checkpoint and replication control. Proc Natl Acad Sci USA 2008; 105:20752-7; PMID:19091954; http://dx.doi.org/10.1073/pnas. 0806917106.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 20752-20757
    • Wilsker, D.1    Petermann, E.2    Helleday, T.3    Bunz, F.4
  • 15
    • 0036118391 scopus 로고    scopus 로고
    • Radiation-induced phosphorylation of Chk1 at S345 is associated with p53-dependent cell cycle arrest pathways
    • PMID:11896572
    • Tian H, Faje AT, Lee SL, Jorgensen TJ. Radiation-induced phosphorylation of Chk1 at S345 is associated with p53-dependent cell cycle arrest pathways. Neoplasia 2002; 4:171-80; PMID:11896572; http://dx.doi.org/10.1038/sj.neo. 7900219.
    • (2002) Neoplasia , vol.4 , pp. 171-180
    • Tian, H.1    Faje, A.T.2    Lee, S.L.3    Jorgensen, T.J.4
  • 16
    • 0033406451 scopus 로고    scopus 로고
    • Sensitization of cancer cells to DNA damage-induced cell death by specific cell cycle G2 checkpoint abrogation
    • PMID:10606229
    • Suganuma M, Kawabe T, Hori H, Funabiki T, Okamoto T. Sensitization of cancer cells to DNA damage-induced cell death by specific cell cycle G2 checkpoint abrogation. Cancer Res 1999; 59:5887-91; PMID:10606229.
    • (1999) Cancer Res , vol.59 , pp. 5887-5891
    • Suganuma, M.1    Kawabe, T.2    Hori, H.3    Funabiki, T.4    Okamoto, T.5
  • 17
    • 4444344407 scopus 로고    scopus 로고
    • G2 checkpoint abrogators as anticancer drugs
    • PMID:15078995
    • Kawabe T. G2 checkpoint abrogators as anticancer drugs. Mol Cancer Ther 2004; 3:513-9; PMID:15078995.
    • (2004) Mol Cancer Ther , vol.3 , pp. 513-519
    • Kawabe, T.1
  • 18
    • 16844384054 scopus 로고    scopus 로고
    • RNA silencing of checkpoint regulators sensitizes p53-defective prostate cancer cells to chemotherapy while sparing normal cells
    • PMID:15805289
    • Mukhopadhyay UK, Senderowicz AM, Ferbeyre G. RNA silencing of checkpoint regulators sensitizes p53-defective prostate cancer cells to chemotherapy while sparing normal cells. Cancer Res 2005; 65:2872-81; PMID:15805289; http://dx.doi.org/10.1158/0008-5472.CAN-04-2502.
    • (2005) Cancer Res , vol.65 , pp. 2872-2881
    • Mukhopadhyay, U.K.1    Senderowicz, A.M.2    Ferbeyre, G.3
  • 19
    • 0033403337 scopus 로고    scopus 로고
    • IFNgamma induction of p21(WAF1) is required for cell cycle inhibition and suppression of apoptosis
    • PMID:10638704
    • Hobeika AC, Etienne W, Torres BA, Johnson HM, Subramaniam PS. IFNgamma induction of p21(WAF1) is required for cell cycle inhibition and suppression of apoptosis. J Interferon Cytokine Res 1999; 19:1351-61; PMID:10638704; http://dx.doi.org/10.1089/107999099312812.
    • (1999) J Interferon Cytokine Res , vol.19 , pp. 1351-1361
    • Hobeika, A.C.1    Etienne, W.2    Torres, B.A.3    Johnson, H.M.4    Subramaniam, P.S.5
  • 20
    • 48249092713 scopus 로고    scopus 로고
    • DNA damage detection and repair pathways - Recent advances with inhibitors of checkpoint kinases in cancer therapy
    • PMID:18593978
    • Ashwell S, Zabludoff S. DNA damage detection and repair pathways - recent advances with inhibitors of checkpoint kinases in cancer therapy. Clin Cancer Res 2008; 14:4032-7; PMID:18593978; http://dx.doi.org/10.1158/1078-0432.CCR-07- 5138.
    • (2008) Clin Cancer Res , vol.14 , pp. 4032-4037
    • Ashwell, S.1    Zabludoff, S.2
  • 21
    • 17644432403 scopus 로고    scopus 로고
    • Chk1 is an essential kinase that is regulated by Atr and required for the G(2)/M DNA damage checkpoint
    • PMID:10859164
    • Liu Q, Guntuku S, Cui XS, Matsuoka S, Cortez D, Tamai K, et al. Chk1 is an essential kinase that is regulated by Atr and required for the G(2)/M DNA damage checkpoint. Genes Dev 2000; 14:1448-59; PMID:10859164.
    • (2000) Genes Dev , vol.14 , pp. 1448-1459
    • Liu, Q.1    Guntuku, S.2    Cui, X.S.3    Matsuoka, S.4    Cortez, D.5    Tamai, K.6
  • 22
    • 77954951751 scopus 로고    scopus 로고
    • Compromise in mRNA processing machinery in senescent human fibroblasts: Implications for a novel potential role of Phospho-ATR (ser428)
    • PMID:20084458
    • Chandris P, Giannouli CC, Panayotou G, Kletsas D. Compromise in mRNA processing machinery in senescent human fibroblasts: implications for a novel potential role of Phospho-ATR (ser428). Biogerontology 2010; 11:421-36; PMID:20084458; http://dx.doi.org/10.1007/s10522-010-9261-z.
    • (2010) Biogerontology , vol.11 , pp. 421-436
    • Chandris, P.1    Giannouli, C.C.2    Panayotou, G.3    Kletsas, D.4
  • 23
    • 65549090186 scopus 로고    scopus 로고
    • DDB1 targets Chk1 to the Cul4 E3 ligase complex in normal cycling cells and in cells experiencing replication stress
    • PMID:19276361
    • Leung-Pineda V, Huh J, Piwnica-Worms H. DDB1 targets Chk1 to the Cul4 E3 ligase complex in normal cycling cells and in cells experiencing replication stress. Cancer Res 2009; 69:2630-7; PMID:19276361; http://dx.doi.org/10.1158/ 0008-5472.CAN-08-3382.
    • (2009) Cancer Res , vol.69 , pp. 2630-2637
    • Leung-Pineda, V.1    Huh, J.2    Piwnica-Worms, H.3
  • 24
    • 70249108452 scopus 로고    scopus 로고
    • Identification of XAF1 as a novel cell cycle regulator through modulating G(2)/M checkpoint and interaction with checkpoint kinase 1 in gastrointestinal cancer
    • PMID:19628579
    • Wang J, Gu Q, Li M, Zhang W, Yang M, Zou B, et al. Identification of XAF1 as a novel cell cycle regulator through modulating G(2)/M checkpoint and interaction with checkpoint kinase 1 in gastrointestinal cancer. Carcinogenesis 2009; 30:1507-16; PMID:19628579; http://dx.doi.org/10.1093/carcin/bgp155.
    • (2009) Carcinogenesis , vol.30 , pp. 1507-1516
    • Wang, J.1    Gu, Q.2    Li, M.3    Zhang, W.4    Yang, M.5    Zou, B.6
  • 25
    • 60149110314 scopus 로고    scopus 로고
    • c-Jun N-terminal kinase (JNK1) upregulates XIAP-associated factor 1 (XAF1) through interferon regulatory factor 1 (IRF-1) in gastrointestinal cancer
    • PMID:19056926
    • Wang J, Zhang W, Zhang Y, Chen Y, Zou B, Jiang B, et al. c-Jun N-terminal kinase (JNK1) upregulates XIAP-associated factor 1 (XAF1) through interferon regulatory factor 1 (IRF-1) in gastrointestinal cancer. Carcinogenesis 2009; 30:222-9; PMID:19056926; http://dx.doi.org/10.1093/carcin/bgn271.
    • (2009) Carcinogenesis , vol.30 , pp. 222-229
    • Wang, J.1    Zhang, W.2    Zhang, Y.3    Chen, Y.4    Zou, B.5    Jiang, B.6
  • 26
    • 34249937178 scopus 로고    scopus 로고
    • The ATR pathway: Fine-tuning the fork
    • Amst PMID:17531546
    • Paulsen RD, Cimprich KA. The ATR pathway: fine-tuning the fork. DNA Repair (Amst) 2007; 6:953-66; PMID:17531546; http://dx.doi.org/10.1016/j.dnarep. 2007.02.015.
    • (2007) DNA Repair , vol.6 , pp. 953-966
    • Paulsen, R.D.1    Cimprich, K.A.2
  • 27
    • 0037484271 scopus 로고    scopus 로고
    • Chk1 mediates S and G2 arrests through Cdc25A degradation in response to DNA-damaging agents
    • PMID:12676925
    • Xiao Z, Chen Z, Gunasekera AH, Sowin TJ, Rosenberg SH, Fesik S, et al. Chk1 mediates S and G2 arrests through Cdc25A degradation in response to DNA-damaging agents. J Biol Chem 2003; 278:21767-73; PMID:12676925; http://dx.doi.org/10.1074/jbc.M300229200.
    • (2003) J Biol Chem , vol.278 , pp. 21767-21773
    • Xiao, Z.1    Chen, Z.2    Gunasekera, A.H.3    Sowin, T.J.4    Rosenberg, S.H.5    Fesik, S.6
  • 28
    • 0012966157 scopus 로고    scopus 로고
    • Chk1 regulates the S phase checkpoint by coupling the physiological turnover and ionizing radiation-induced accelerated proteolysis of Cdc25A
    • PMID:12676583
    • Sørensen CS, Syljuåsen RG, Falck J, Schroeder T, Rönnstrand L, Khanna KK, et al. Chk1 regulates the S phase checkpoint by coupling the physiological turnover and ionizing radiation-induced accelerated proteolysis of Cdc25A. Cancer Cell 2003; 3:247-58; PMID:12676583; http://dx.doi.org/10.1016/S1535-6108(03)00048-5.
    • (2003) Cancer Cell , vol.3 , pp. 247-258
    • Sørensen, C.S.1    Syljuåsen, R.G.2    Falck, J.3    Schroeder, T.4    Rönnstrand, L.5    Khanna, K.K.6
  • 29
    • 0018098799 scopus 로고
    • Interferon affects both G1 and S + G2 in cells stimulated from quiescence to growth
    • PMID:683317
    • Balkwill F, Taylor-Papadimitriou J. Interferon affects both G1 and S + G2 in cells stimulated from quiescence to growth. Nature 1978; 274:798-800; PMID:683317; http://dx.doi.org/10.1038/274798a0.
    • (1978) Nature , vol.274 , pp. 798-800
    • Balkwill, F.1    Taylor-Papadimitriou, J.2
  • 30
    • 0019435294 scopus 로고
    • Block of glioma cell line in S by interferon
    • PMID:6169666
    • Lundblad D, Lundgren E. Block of glioma cell line in S by interferon. Int J Cancer 1981; 27:749-54; PMID:6169666; http://dx.doi.org/10.1002/ijc. 2910270604.
    • (1981) Int J Cancer , vol.27 , pp. 749-754
    • Lundblad, D.1    Lundgren, E.2
  • 31
    • 33745363911 scopus 로고    scopus 로고
    • DNA damage signaling and p53-dependent senescence after prolonged beta-interferon stimulation
    • PMID:16436515
    • Moiseeva O, Mallette FA, Mukhopadhyay UK, Moores A, Ferbeyre G. DNA damage signaling and p53-dependent senescence after prolonged beta-interferon stimulation. Mol Biol Cell 2006; 17:1583-92; PMID:16436515; http://dx.doi.org/ 10.1091/mbc.E05-09-0858.
    • (2006) Mol Biol Cell , vol.17 , pp. 1583-1592
    • Moiseeva, O.1    Mallette, F.A.2    Mukhopadhyay, U.K.3    Moores, A.4    Ferbeyre, G.5
  • 32
    • 29244484430 scopus 로고    scopus 로고
    • Radiation and new molecular agents part I: Targeting ATM-ATR checkpoints, DNA repair and the proteasome
    • PMID:16378907
    • Choudhury A, Cuddihy A, Bristow RG. Radiation and new molecular agents part I: targeting ATM-ATR checkpoints, DNA repair and the proteasome. Semin Radiat Oncol 2006; 16:51-8; PMID:16378907; http://dx.doi.org/10.1016/j. semradonc.2005.08.007.
    • (2006) Semin Radiat Oncol , vol.16 , pp. 51-58
    • Choudhury, A.1    Cuddihy, A.2    Bristow, R.G.3
  • 33
    • 68949221708 scopus 로고    scopus 로고
    • The F box protein Fbx6 regulates Chk1 stability and cellular sensitivity to replication stress
    • PMID:19716789
    • Zhang YW, Brognard J, Coughlin C, You Z, Dolled-Filhart M, Aslanian A, et al. The F box protein Fbx6 regulates Chk1 stability and cellular sensitivity to replication stress. Mol Cell 2009; 35:442-53; PMID:19716789; http://dx.doi.org/10.1016/j.molcel.2009.06.030.
    • (2009) Mol Cell , vol.35 , pp. 442-453
    • Zhang, Y.W.1    Brognard, J.2    Coughlin, C.3    You, Z.4    Dolled-Filhart, M.5    Aslanian, A.6
  • 34
    • 34548817572 scopus 로고    scopus 로고
    • Degradation of survivin by the X-linked inhibitor of apoptosis (XIAP)-XAF1 complex
    • PMID:17613533
    • Arora V, Cheung HH, Plenchette S, Micali OC, Liston P, Korneluk RG. Degradation of survivin by the X-linked inhibitor of apoptosis (XIAP)-XAF1 complex. J Biol Chem 2007; 282:26202-9; PMID:17613533; http://dx.doi.org/10. 1074/jbc.M700776200.
    • (2007) J Biol Chem , vol.282 , pp. 26202-26209
    • Arora, V.1    Cheung, H.H.2    Plenchette, S.3    Micali, O.C.4    Liston, P.5    Korneluk, R.G.6
  • 35
    • 0842303214 scopus 로고    scopus 로고
    • Interaction of checkpoint kinase 1 and the X-linked inhibitor of apoptosis during mitosis
    • PMID:14759516
    • Galvan V, Kurakin AV, Bredesen DE. Interaction of checkpoint kinase 1 and the X-linked inhibitor of apoptosis during mitosis. FEBS Lett 2004; 558:57-62; PMID:14759516; http://dx.doi.org/10.1016/S0014-5793(03)01488-1.
    • (2004) FEBS Lett , vol.558 , pp. 57-62
    • Galvan, V.1    Kurakin, A.V.2    Bredesen, D.E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.