메뉴 건너뛰기




Volumn 9, Issue 3, 2012, Pages 148-152

Genesis of the myofibroblast in lung injury and fibrosis

Author keywords

Cell differentiation; Epigenetic regulation; Transcriptional regulation

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; HISTONE DEACETYLASE 4; MICRORNA 192; TRANSFORMING GROWTH FACTOR BETA; TRICHOSTATIN A;

EID: 84865827400     PISSN: 15463222     EISSN: 19435665     Source Type: Journal    
DOI: 10.1513/pats.201201-011AW     Document Type: Conference Paper
Times cited : (103)

References (55)
  • 2
    • 42049109737 scopus 로고    scopus 로고
    • Biology of fibroblasts and myofibroblasts
    • Phan SH. Biology of fibroblasts and myofibroblasts. Proc Am Thorac Soc 2008;5:334-337.
    • (2008) Proc Am Thorac Soc , vol.5 , pp. 334-337
    • Phan, S.H.1
  • 3
    • 0028278029 scopus 로고
    • Myofibroblasts and their role in lung collagen gene expression during pulmonary fibrosis: A combined immunohistochemical and in situ hybridization study
    • Zhang K, Rekhter MD, Gordon D, Phan SH. Myofibroblasts and their role in lung collagen gene expression during pulmonary fibrosis: a combined immunohistochemical and in situ hybridization study. Am J Pathol 1994;145:114-125.
    • (1994) Am J Pathol , vol.145 , pp. 114-125
    • Zhang, K.1    Rekhter, M.D.2    Gordon, D.3    Phan, S.H.4
  • 6
    • 17844384822 scopus 로고    scopus 로고
    • Induction of epithelial-mesenchymal transition in alveolar epithelial cells by transforming growth factor-beta1: Potential role in idiopathic pulmonary fibrosis
    • Willis BC, Liebler JM, Luby-Phelps K, Nicholson AG, Crandall ED, du Bois RM, Borok Z. Induction of epithelial-mesenchymal transition in alveolar epithelial cells by transforming growth factor-beta1: potential role in idiopathic pulmonary fibrosis. Am J Pathol 2005;166:1321-1332.
    • (2005) Am J Pathol , vol.166 , pp. 1321-1332
    • Willis, B.C.1    Liebler, J.M.2    Luby-Phelps, K.3    Nicholson, A.G.4    Crandall, E.D.5    Du Bois, R.M.6    Borok, Z.7
  • 13
    • 79955123951 scopus 로고    scopus 로고
    • Lineage tracing demonstrates no evidence of cholangiocyte epithelial-to-mesenchymal transition in murine models of hepatic fibrosis
    • Chu AS, Diaz R, Hui JJ, Yanger K, Zong Y, Alpini G, Stanger BZ, Wells RG. Lineage tracing demonstrates no evidence of cholangiocyte epithelial-to- mesenchymal transition in murine models of hepatic fibrosis. Hepatology 2011;53:1685-1695.
    • (2011) Hepatology , vol.53 , pp. 1685-1695
    • Chu, A.S.1    Diaz, R.2    Hui, J.J.3    Yanger, K.4    Zong, Y.5    Alpini, G.6    Stanger, B.Z.7    Wells, R.G.8
  • 15
    • 0028535872 scopus 로고
    • Circulating fibrocytes define a new leukocyte subpopulation that mediates tissue repair
    • Bucala R, Spiegel LA, Chesney J, Hogan M, Cerami A. Circulating fibrocytes define a new leukocyte subpopulation that mediates tissue repair. Mol Med 1994;1:71-81.
    • (1994) Mol Med , vol.1 , pp. 71-81
    • Bucala, R.1    Spiegel, L.A.2    Chesney, J.3    Hogan, M.4    Cerami, A.5
  • 16
    • 0031000283 scopus 로고    scopus 로고
    • The peripheral blood fibrocyte is a potent antigen-presenting cell capable of priming naive T cells in situ
    • Chesney J, Bacher M, Bender A, Bucala R. The peripheral blood fibrocyte is a potent antigen-presenting cell capable of priming naive T cells in situ. Proc Natl Acad Sci USA 1997;94:6307-6312.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 6307-6312
    • Chesney, J.1    Bacher, M.2    Bender, A.3    Bucala, R.4
  • 17
    • 0035877019 scopus 로고    scopus 로고
    • Peripheral blood fibrocytes: Differentiation pathway and migration to wound sites
    • Abe R, Donnelly SC, Peng T, Bucala R, Metz CN. Peripheral blood fibrocytes: differentiation pathway and migration to wound sites. J Immunol 2001;166:7556-7562.
    • (2001) J Immunol , vol.166 , pp. 7556-7562
    • Abe, R.1    Donnelly, S.C.2    Peng, T.3    Bucala, R.4    Metz, C.N.5
  • 19
    • 4444332042 scopus 로고    scopus 로고
    • Contribution of bone marrow-derived cells to skin: Collagen deposition and wound repair
    • Fathke C, Wilson L, Hutter J, Kapoor V, Smith A, Hocking A, Isik F. Contribution of bone marrow-derived cells to skin: collagen deposition and wound repair. Stem Cells 2004;22:812-822.
    • (2004) Stem Cells , vol.22 , pp. 812-822
    • Fathke, C.1    Wilson, L.2    Hutter, J.3    Kapoor, V.4    Smith, A.5    Hocking, A.6    Isik, F.7
  • 20
    • 77953544771 scopus 로고    scopus 로고
    • Fibrocytes in health and disease
    • Herzog EL, Bucala R. Fibrocytes in health and disease. Exp Hematol 2010;38:548-556.
    • (2010) Exp Hematol , vol.38 , pp. 548-556
    • Herzog, E.L.1    Bucala, R.2
  • 22
    • 13544263380 scopus 로고    scopus 로고
    • Fibrocytes contribute to the myofibroblast population in wounded skin and originate from the bone marrow
    • Mori L, Bellini A, Stacey MA, Schmidt M, Mattoli S. Fibrocytes contribute to the myofibroblast population in wounded skin and originate from the bone marrow. Exp Cell Res 2005;304:81-90.
    • (2005) Exp Cell Res , vol.304 , pp. 81-90
    • Mori, L.1    Bellini, A.2    Stacey, M.A.3    Schmidt, M.4    Mattoli, S.5
  • 24
    • 33645523825 scopus 로고    scopus 로고
    • Bone marrow lacks a transplantable progenitor for smooth muscle type alpha-actin-expressing cells
    • Yokota T, Kawakami Y, Nagai Y, Ma JX, Tsai JY, Kincade PW, Sato S. Bone marrow lacks a transplantable progenitor for smooth muscle type alpha-actin-expressing cells. Stem Cells 2006;24:13-22.
    • (2006) Stem Cells , vol.24 , pp. 13-22
    • Yokota, T.1    Kawakami, Y.2    Nagai, Y.3    Ma, J.X.4    Tsai, J.Y.5    Kincade, P.W.6    Sato, S.7
  • 26
    • 59649107771 scopus 로고    scopus 로고
    • Role of stem cell factor and bone marrow-derived fibroblasts in airway remodeling
    • Dolgachev VA, Ullenbruch MR, Lukacs NW, Phan SH. Role of stem cell factor and bone marrow-derived fibroblasts in airway remodeling. Am J Pathol 2009;174:390-400.
    • (2009) Am J Pathol , vol.174 , pp. 390-400
    • Dolgachev, V.A.1    Ullenbruch, M.R.2    Lukacs, N.W.3    Phan, S.H.4
  • 27
    • 0142104985 scopus 로고    scopus 로고
    • Smad-dependent and Smad-independent pathways in TGF-beta family signalling
    • Derynck R, Zhang YE. Smad-dependent and Smad-independent pathways in TGF-beta family signalling. Nature 2003;425:577-584.
    • (2003) Nature , vol.425 , pp. 577-584
    • Derynck, R.1    Zhang, Y.E.2
  • 28
    • 0034778401 scopus 로고    scopus 로고
    • Focal adhesion features during myofibroblastic differentiation are controlled by intracellular and extracellular factors
    • Dugina V, Fontao L, Chaponnier C, Vasiliev J, Gabbiani G. Focal adhesion features during myofibroblastic differentiation are controlled by intracellular and extracellular factors. J Cell Sci 2001;114:3285-3296.
    • (2001) J Cell Sci , vol.114 , pp. 3285-3296
    • Dugina, V.1    Fontao, L.2    Chaponnier, C.3    Vasiliev, J.4    Gabbiani, G.5
  • 29
    • 0035149573 scopus 로고    scopus 로고
    • Transforming growth factor-beta1 induces phenotypic modulation of human lung fibroblasts to myofibroblast through a c-Jun-NH2-terminal kinase-dependent pathway
    • Hashimoto S, Gon Y, Takeshita I, Matsumoto K, Maruoka S, Horie T. Transforming growth factor-beta1 induces phenotypic modulation of human lung fibroblasts to myofibroblast through a c-Jun-NH2-terminal kinase-dependent pathway. Am J Respir Crit Care Med 2001;163:152-157.
    • (2001) Am J Respir Crit Care Med , vol.163 , pp. 152-157
    • Hashimoto, S.1    Gon, Y.2    Takeshita, I.3    Matsumoto, K.4    Maruoka, S.5    Horie, T.6
  • 32
    • 24344500807 scopus 로고    scopus 로고
    • Smad2 and Smad3 play different roles in rat hepatic stellate cell function and alpha-smooth muscle actin organization
    • Uemura M, Swenson ES, Gaca MD, Giordano FJ, Reiss M, Wells RG. Smad2 and Smad3 play different roles in rat hepatic stellate cell function and alpha-smooth muscle actin organization. Mol Biol Cell 2005;16:4214-4224.
    • (2005) Mol Biol Cell , vol.16 , pp. 4214-4224
    • Uemura, M.1    Swenson, E.S.2    Gaca, M.D.3    Giordano, F.J.4    Reiss, M.5    Wells, R.G.6
  • 33
    • 0037183986 scopus 로고    scopus 로고
    • Vascular smooth muscle alpha-actin gene transcription during myofibroblast differentiation requires Sp1/3 protein binding proximal to the MCAT enhancer
    • Cogan JG, Subramanian SV, Polikandriotis JA, Kelm RJ Jr, Strauch AR. Vascular smooth muscle alpha-actin gene transcription during myofibroblast differentiation requires Sp1/3 protein binding proximal to the MCAT enhancer. J Biol Chem 2002;277:36433-36442.
    • (2002) J Biol Chem , vol.277 , pp. 36433-36442
    • Cogan, J.G.1    Subramanian, S.V.2    Polikandriotis, J.A.3    Kelm Jr., R.J.4    Strauch, A.R.5
  • 34
    • 0042831330 scopus 로고    scopus 로고
    • Smad3 mediates transforming growth factor-beta-induced alpha-smooth muscle actin expression
    • Hu B, Wu Z, Phan SH. Smad3 mediates transforming growth factor-beta-induced alpha-smooth muscle actin expression. Am J Respir Cell Mol Biol 2003;29:397-404.
    • (2003) Am J Respir Cell Mol Biol , vol.29 , pp. 397-404
    • Hu, B.1    Wu, Z.2    Phan, S.H.3
  • 35
    • 43049148411 scopus 로고    scopus 로고
    • Cancer-derived lysophosphatidic acid stimulates differentiation of human mesenchymal stem cells to myofibroblast- like cells
    • Jeon ES, Moon HJ, Lee MJ, Song HY, Kim YM, Cho M, Suh DS, Yoon MS, Chang CL, Jung JS, et al. Cancer-derived lysophosphatidic acid stimulates differentiation of human mesenchymal stem cells to myofibroblast- like cells. Stem Cells 2008;26:789-797.
    • (2008) Stem Cells , vol.26 , pp. 789-797
    • Jeon, E.S.1    Moon, H.J.2    Lee, M.J.3    Song, H.Y.4    Kim, Y.M.5    Cho, M.6    Suh, D.S.7    Yoon, M.S.8    Chang, C.L.9    Jung, J.S.10
  • 37
    • 1842524153 scopus 로고    scopus 로고
    • Integration of TGF-beta/ Smad and Jagged1/Notch signalling in epithelial-to-mesenchymal transition
    • Zavadil J, Cermak L, Soto-Nieves N, Bottinger EP. Integration of TGF-beta/ Smad and Jagged1/Notch signalling in epithelial-to-mesenchymal transition. EMBO J 2004;23:1155-1165.
    • (2004) EMBO J , vol.23 , pp. 1155-1165
    • Zavadil, J.1    Cermak, L.2    Soto-Nieves, N.3    Bottinger, E.P.4
  • 40
    • 63349111610 scopus 로고    scopus 로고
    • Transcriptional regulation of SM22α by Wnt3a: Convergence with TGFβ1/Smad signaling at a novel regulatory element
    • Shafer SL, Towler DA. Transcriptional regulation of SM22α by Wnt3a: convergence with TGFβ1/Smad signaling at a novel regulatory element. J Mol Cell Cardiol 2009;46:621-635.
    • (2009) J Mol Cell Cardiol , vol.46 , pp. 621-635
    • Shafer, S.L.1    Towler, D.A.2
  • 41
    • 79959482541 scopus 로고    scopus 로고
    • Hedgehog signaling and pancreatic tumor development
    • Lauth M, Toftgård R. Hedgehog signaling and pancreatic tumor development. Adv Cancer Res 2011;110:1-17.
    • (2011) Adv Cancer Res , vol.110 , pp. 1-17
    • Lauth, M.1    Toftgård, R.2
  • 42
    • 41549108935 scopus 로고    scopus 로고
    • Idiopathic pulmonary fibrosis: Aberrant recapitulation of developmental programs?
    • Selman M, Pardo A, Kaminski N. Idiopathic pulmonary fibrosis: aberrant recapitulation of developmental programs? PLoS Med 2008; 5:e62.
    • (2008) PLoS Med , vol.5
    • Selman, M.1    Pardo, A.2    Kaminski, N.3
  • 43
    • 27644456575 scopus 로고    scopus 로고
    • NAD(P)H oxidase 4 mediates transforming growth factor-beta1-induced differentiation of cardiac fibroblasts into myofibroblasts
    • Cucoranu I, Clempus R, Dikalova A, Phelan PJ, Ariyan S, Dikalov S, Sorescu D. NAD(P)H oxidase 4 mediates transforming growth factor-beta1-induced differentiation of cardiac fibroblasts into myofibroblasts. Circ Res 2005;97:900-907.
    • (2005) Circ Res , vol.97 , pp. 900-907
    • Cucoranu, I.1    Clempus, R.2    Dikalova, A.3    Phelan, P.J.4    Ariyan, S.5    Dikalov, S.6    Sorescu, D.7
  • 45
    • 80053612684 scopus 로고    scopus 로고
    • C/EBPβ-Thr217 phosphorylation signaling contributes to the development of lung injury and fibrosis in mice
    • Buck M, Chojkier M. C/EBPβ-Thr217 phosphorylation signaling contributes to the development of lung injury and fibrosis in mice. PLoS ONE 2011;6:e25497.
    • (2011) PLoS ONE , vol.6
    • Buck, M.1    Chojkier, M.2
  • 46
    • 80855143589 scopus 로고    scopus 로고
    • Myocardin-related transcription factors A and B are key regulators of TGF-beta1-induced fibroblast to myofibroblast differentiation
    • Crider BJ, Risinger GM Jr, Haaksma CJ, Howard EW, Tomasek JJ. Myocardin-related transcription factors A and B are key regulators of TGF-beta1-induced fibroblast to myofibroblast differentiation. J Invest Dermatol 2011;131:2378-2385.
    • (2011) J Invest Dermatol , vol.131 , pp. 2378-2385
    • Crider, B.J.1    Risinger Jr., G.M.2    Haaksma, C.J.3    Howard, E.W.4    Tomasek, J.J.5
  • 47
  • 48
    • 0033055983 scopus 로고    scopus 로고
    • A histone deacetylase inhibitor, trichostatin A, suppresses myofibroblastic differentiation of rat hepatic stellate cells in primary culture
    • Niki T, Rombouts K, De Bleser P, De Smet K, Rogiers V, Schuppan D, Yoshida M, Gabbiani G, Geerts A. A histone deacetylase inhibitor, trichostatin A, suppresses myofibroblastic differentiation of rat hepatic stellate cells in primary culture. Hepatology 1999;29:858-867.
    • (1999) Hepatology , vol.29 , pp. 858-867
    • Niki, T.1    Rombouts, K.2    De Bleser, P.3    De Smet, K.4    Rogiers, V.5    Schuppan, D.6    Yoshida, M.7    Gabbiani, G.8    Geerts, A.9
  • 49
    • 34848863333 scopus 로고    scopus 로고
    • Histone deacetylase 4 is required for TGFbeta1-induced myofibroblastic differentiation
    • Glenisson W, Castronovo V, Waltregny D. Histone deacetylase 4 is required for TGFbeta1-induced myofibroblastic differentiation. Biochim Biophys Acta 2007;1773:1572-1582.
    • (2007) Biochim Biophys Acta , vol.1773 , pp. 1572-1582
    • Glenisson, W.1    Castronovo, V.2    Waltregny, D.3
  • 50
    • 72449139586 scopus 로고    scopus 로고
    • Abrogation of TGF-beta1- induced fibroblast-myofibroblast differentiation by histone deacetylase inhibition
    • Guo W, Shan B, Klingsberg RC, Qin X, Lasky JA. Abrogation of TGF-beta1- induced fibroblast-myofibroblast differentiation by histone deacetylase inhibition. Am J Physiol Lung Cell Mol Physiol 2009;297: L864-L870.
    • (2009) Am J Physiol Lung Cell Mol Physiol , vol.297
    • Guo, W.1    Shan, B.2    Klingsberg, R.C.3    Qin, X.4    Lasky, J.A.5
  • 52
    • 75149141045 scopus 로고    scopus 로고
    • MeCP2 controls an epigenetic pathway that promotes myofibroblast transdifferentiation and fibrosis
    • Mann J, Chu DC, Maxwell A, Oakley F, Zhu NL, Tsukamoto H, Mann DA. MeCP2 controls an epigenetic pathway that promotes myofibroblast transdifferentiation and fibrosis. Gastroenterology 2010;138:705-714.
    • (2010) Gastroenterology , vol.138 , pp. 705-714
    • Mann, J.1    Chu, D.C.2    Maxwell, A.3    Oakley, F.4    Zhu, N.L.5    Tsukamoto, H.6    Mann, D.A.7
  • 53
    • 77954614145 scopus 로고    scopus 로고
    • Epigenetic regulation of myofibroblast differentiation by DNA methylation
    • Hu B, Gharaee-Kermani M, Wu Z, Phan SH. Epigenetic regulation of myofibroblast differentiation by DNA methylation. Am J Pathol 2010;177:21-28.
    • (2010) Am J Pathol , vol.177 , pp. 21-28
    • Hu, B.1    Gharaee-Kermani, M.2    Wu, Z.3    Phan, S.H.4
  • 54
    • 79953665837 scopus 로고    scopus 로고
    • Essential role of MeCP2 in the regulation of myofibroblast differentiation during pulmonary fibrosis
    • Hu B, Gharaee-Kermani M, Wu Z, Phan SH. Essential role of MeCP2 in the regulation of myofibroblast differentiation during pulmonary fibrosis. Am J Pathol 2011;178:1500-1508.
    • (2011) Am J Pathol , vol.178 , pp. 1500-1508
    • Hu, B.1    Gharaee-Kermani, M.2    Wu, Z.3    Phan, S.H.4
  • 55
    • 79952790398 scopus 로고    scopus 로고
    • MicroRNAs in idiopathic pulmonary fibrosis
    • Pandit KV, Milosevic J, Kaminski N. MicroRNAs in idiopathic pulmonary fibrosis. Transl Res 2011;157:191-199.
    • (2011) Transl Res , vol.157 , pp. 191-199
    • Pandit, K.V.1    Milosevic, J.2    Kaminski, N.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.