Fibrocytes contribute to the myofibroblast population in wounded skin and originate from the bone marrow

Experimental Cell Research

Volumn 304, Issue 1, 2005, Pages 81-90

  Mori, Luca ^a   Bellini, Alberto ^a   Stacey, Martin A ^a   Schmidt, Matthias ^a   Mattoli, Sabrina ^a,b  

^a Scientific Direction and Project Management Avail Biomedical Research Institute   (Switzerland)

^b Avail GmbH   (Switzerland)

Author keywords

Cell differentiation; Fibrocytes; Fibrosis; Myofibroblasts; Tissue remodeling; Tissue repair; Wound healing

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; CD14 ANTIGEN; CD34 ANTIGEN; CD45 ANTIGEN; COLLAGEN TYPE 1; MICROSOMAL AMINOPEPTIDASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN EXPRESSION; ARTICLE; BONE MARROW; BONE MARROW TRANSPLANTATION; CELL ISOLATION; CELL SUBPOPULATION; CONTROLLED STUDY; FEMALE; FIBROBLAST; FLUORESCENCE ACTIVATED CELL SORTING; GENE EXPRESSION; GRANULATION TISSUE; IN SITU HYBRIDIZATION; MALE; MYOFIBROBLAST; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SKIN INJURY; TIME SERIES ANALYSIS; WHOLE BODY RADIATION; WOUND CLOSURE; Y CHROMOSOME;

ANIMALIA;

EID: 13544263380     PISSN: 00144827     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.yexcr.2004.11.011     Document Type: Article

References (17)

1. G. Gabbiani The myofibroblast in wound healing and fibrocontractive diseases J. Pathol. 200 2003 500 503
2. J. Jester, W. Petroll, and H. Cavanagh Corneal stromal wound healing in refractory surgery: the role of myofibroblasts Prog. Retinal Eye Res. 18 1999 311 356
3. D. Powell, R. Mifflin, J. Valentich, S. Crowe, J. Saada, and A. West Myofibroblasts: I. Paracrine cells important in health and disease Am. J. Physiol. 277 1999 C1 C9
4. D. Lanning, R. Diegelmann, D. Yager, M. Wallace, C. Bagwell, and J. Haynes Myofibroblast induction with transforming factor-1 and -3 in cutaneous fetal excision wounds J. Pediatr. Surg. 35 2000 183 187
5. M. Brittan, T. Hunt, R. Jeffery, R. Poulsom, S.J. Forbes, K. Hodivala-Dilke, J. Goldman, M.R. Alison, and N.A. Wright Bone marrow derivation of pericryptal myofibroblasts in the mouse and human small intestine and colon Gut 50 2002 752 757
6. N.C. Direzke, S.J. Forbes, M. Brittan, T. Hunt, R. Jeffery, S.L. Preston, R. Poulsom, K. Hodivala-Dilke, M.R. Alison, and N.A. Wright Multiple organ engraftment by bone-marrow-derived myofibroblasts and fibroblast in bone-marrow-transplanted mice Stem. Cells 21 2003 514 520
7. M. Schmidt, G. Sun, M.A. Stacey, L. Mori, and S. Mattoli Identification of circulating fibrocytes as precursors of bronchial myofibroblasts in asthma J. Immunol. 171 2003 380 389
8. C.N. Metz Fibrocytes: a unique cell population implicated in wound healing Cell. Mol. Life Sci. 60 2003 1342 1350
9. R. Bucala, L.A. Spiegel, J. Chesney, M. Hogan, and A. Cerami Circulating fibrocytes define a new leukocyte subpopulation that mediates tissue repair Mol. Med. 1 1994 71 81
10. R. Abe, S.C. Donnelly, T. Peng, R. Bucala, and C.N. Metz Peripheral blood fibrocytes: differentiation pathway and migration to wound sites J. Immunol. 166 2001 7556 7562
11. R.J. Phillips, M.D. Burdick, K. Hong, M.A. Lutz, L.A. Murray, Y.Y. Xue, J.A. Belperio, M.P. Keane, and R.M. Strieter Circulating fibrocytes traffic to the lungs in response to CXCL12 and mediate fibrosis J. Clin. Invest. 114 2004 438 446
12. 1 causes airway fibrosis and increase collagen I and III mRNA in mice Thorax 58 2003 772 777
13. B.H. Min, A.R. Strauch, and D.N. Foster Nucleotide sequence of a mouse vascular smooth muscle alpha-actin cDNA Nucleic Acids Res. 16 1988 10374
14. J.E. Coligan, A.M. Kruisbeek, D.H. Margulies, E.M. Shevach, and W. Strober The CD system of leukocyte cell surface molecules Curr. Protocol. Immunol. vol. 2 1992 Wiley New York A.4.1 A.4.28
15. S. Werner, and R. Grose Regulation of wound healing by growth factors and cytokines Physiol. Rev. 83 2003 835 870
16. C. Frathke, L. Wilson, J. Hutter, V. Kapoor, A. Smith, A. Hocking, and F. Isik Contribution of bone-marrow-derived cells to skin: collagen deposition and wound repair Stem. Cells 22 2004 812 822
17. L. Fina, H.V. Molgaard, D. Robertson, N.J. Bradley, P. Monaghan, D. Delia, D.R. Sutherland, M.A. Baker, and M.F. Greaves Expression of the CD34 gene in vascular endothelial cells Blood 75 1990 2417 2426