Loss of a single allele for Ku80 leads to progenitor dysfunction and accelerated aging in skeletal muscle

EMBO Molecular Medicine

Volumn 4, Issue 9, 2012, Pages 910-923

  Didier, Nathalie ^a   Hourdé, Christophe ^b   Amthor, Helge ^b   Marazzi, Giovanna ^a   Sassoon, David ^a  

^a INSERM   (France)

^b SORBONNE UNIVERSITÉ   (France)

Author keywords

Aging; Ku80; Skeletal muscle; Stem cells; Telomere

Indexed keywords

DNA; KU80 PROTEIN; PROTEIN; PROTEIN KINASE B; PROTEIN P53; SOMATOMEDIN C; UNCLASSIFIED DRUG;

AGING; ALLELE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL RENEWAL; CELLULAR STRESS RESPONSE; CONTROLLED STUDY; DNA DAMAGE; GENE FUNCTION; MOUSE; MUSCLE ATROPHY; MUSCLE DEVELOPMENT; MUSCLE REGENERATION; MYOBLAST; NONHUMAN; POSTNATAL DEVELOPMENT; PRIORITY JOURNAL; SKELETAL MUSCLE ATROPHY; STEM CELL; TELOMERE SHORTENING;

AGING; ALLELES; ANIMALS; ANTIGENS, NUCLEAR; DNA-BINDING PROTEINS; MICE; MICE, KNOCKOUT; MUSCLE, SKELETAL; MUSCULAR ATROPHY;

EID: 84865737521     PISSN: 17574676     EISSN: 17574684     Source Type: Journal    
DOI: 10.1002/emmm.201101075     Document Type: Article

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