-
1
-
-
0033012398
-
Chemokine receptors as HIV-1 coreceptors: Roles in viral entry, tropism, and disease
-
Berger EA, Murphy PM, Farber JM. Chemokine receptors as HIV-1 coreceptors: Roles in viral entry, tropism, and disease. Annu Rev Immunol 1999; 17:657-700.
-
(1999)
Annu Rev Immunol
, vol.17
, pp. 657-700
-
-
Berger, E.A.1
Murphy, P.M.2
Farber, J.M.3
-
2
-
-
33745440781
-
HIV tropism: Diagnostic tools and implications for disease progression and treatment with entry inhibitors
-
Poveda E, Briz V, Quinones-Mateu M, Soriano V. HIV tropism: Diagnostic tools and implications for disease progression and treatment with entry inhibitors. AIDS 2006; 20:1359-1367.
-
(2006)
AIDS
, vol.20
, pp. 1359-1367
-
-
Poveda, E.1
Briz, V.2
Quinones-Mateu, M.3
Soriano, V.4
-
4
-
-
0034523325
-
Envelope V3 amino acid sequence predicts HIV-1 phenotype (co-receptor usage and tropism for macrophages)
-
Briggs DR, Tuttle DL, Sleasman JW, GoodenowMM. Envelope V3 amino acid sequence predicts HIV-1 phenotype (co-receptor usage and tropism for macrophages). AIDS 2000; 14:2937-2939.
-
(2000)
AIDS
, vol.14
, pp. 2937-2939
-
-
Briggs, D.R.1
Tuttle, D.L.2
Sleasman, J.W.3
Goodenow, M.M.4
-
5
-
-
0038637409
-
Predicting HIV-1 coreceptor usage with sequence analysis
-
Jensen MA, van't Wout AB. Predicting HIV-1 coreceptor usage with sequence analysis. AIDS Rev 2003; 5:104-112.
-
(2003)
AIDS Rev
, vol.5
, pp. 104-112
-
-
Jensen, M.A.1
Van't Wout, A.B.2
-
6
-
-
0026606727
-
Phenotype-associated sequence variation in the third variable domain of the human immunodeficiency virus type 1 gp120 molecule
-
Fouchier RA, Groenink M, Kootstra NA, et al. Phenotype-associated sequence variation in the third variable domain of the human immunodeficiency virus type 1 gp120 molecule. J Virol 1992; 66:3183- 3187.
-
(1992)
J Virol
, vol.66
, pp. 3183-3187
-
-
Fouchier, R.A.1
Groenink, M.2
Kootstra, N.A.3
-
7
-
-
0031042433
-
The HIV coreceptors CXCR4 and CCR5 are differentially expressed and regulated on human t lymphocytes
-
Bleul CC, Wu L, Hoxie JA, et al. The HIV coreceptors CXCR4 and CCR5 are differentially expressed and regulated on human T lymphocytes. Proc Natl Acad Sci U S A 1997; 94:1925-1930.
-
(1997)
Proc Natl Acad Sci U S A
, vol.94
, pp. 1925-1930
-
-
Bleul, C.C.1
Wu, L.2
Hoxie, J.A.3
-
8
-
-
0033609149
-
Quantification of CD4, CCR5, and CXCR4 levels on lymphocyte subsets, dendritic cells, and differentially conditioned monocyte-derived macrophages
-
Lee B, Sharron M, Montaner LJ, et al. Quantification of CD4, CCR5, and CXCR4 levels on lymphocyte subsets, dendritic cells, and differentially conditioned monocyte-derived macrophages. Proc Natl Acad Sci U S A 1999; 96:5215-5220.
-
(1999)
Proc Natl Acad Sci U S
, vol.96
, pp. 5215-5220
-
-
Lee, B.1
Sharron, M.2
Montaner, L.J.3
-
9
-
-
63449124466
-
Emerging concepts in the immunopathogenesis of AIDS
-
Douek DC, Roederer M, Koup RA. Emerging concepts in the immunopathogenesis of AIDS. Annu Rev Med 2009; 60:471-484.
-
(2009)
Annu Rev Med
, vol.60
, pp. 471-484
-
-
Douek, D.C.1
Roederer, M.2
Koup, R.A.3
-
10
-
-
4644342929
-
CD4 T cell depletion during all stages of HIV disease occurs predominantly in the gastrointestinal tract
-
Brenchley JM, Schacker TW, Ruff LE, et al. CD4 T cell depletion during all stages of HIV disease occurs predominantly in the gastrointestinal tract. J Exp Med 2004; 200:749-759.
-
(2004)
J Exp Med
, vol.200
, pp. 749-759
-
-
Brenchley, J.M.1
Schacker, T.W.2
Ruff, L.E.3
-
11
-
-
4644289983
-
Primary HIV-1 infection is associated with preferential depletion of CD4 T lymphocytes from effectorsites in the gastrointestinal tract
-
Mehandru S, Poles MA, Tenner-Racz K, et al. Primary HIV-1 infection is associated with preferential depletion of CD4 T lymphocytes from effectorsites in the gastrointestinal tract. J Exp Med 2004; 200:761-770.
-
(2004)
J Exp Med
, vol.200
, pp. 761-770
-
-
Mehandru, S.1
Poles, M.A.2
Tenner-Racz, K.3
-
12
-
-
0033585447
-
Distribution of the human immunodeficiency virus coreceptors CXCR4 and CCR5 in fetal lymphoid organs: Implications for pathogenesis in utero
-
Kitchen SG, Zack JA. Distribution of the human immunodeficiency virus coreceptors CXCR4 and CCR5 in fetal lymphoid organs: Implications for pathogenesis in utero. AIDS Res Hum Retroviruses 1999; 15:143- 148.
-
(1999)
AIDS Res Hum Retroviruses
, vol.15
, pp. 143-148
-
-
Kitchen, S.G.1
Zack, J.A.2
-
13
-
-
0031925974
-
In vivo distribution of the human immunodeficiency virus/simian immunodeficiency virus coreceptors: CXCR4, CCR3, and CCR5
-
Zhang L, He T, Talal A, et al. In vivo distribution of the human immunodeficiency virus/simian immunodeficiency virus coreceptors: CXCR4, CCR3, and CCR5. J Virol 1998; 72:5035-5045.
-
(1998)
J Virol
, vol.72
, pp. 5035-5045
-
-
Zhang, L.1
He, T.2
Talal, A.3
-
14
-
-
0033831646
-
Lamina propria lymphocytes, not macrophages, express CCR5 and CXCR4 and are the likely target cell for human immunodeficiency virus type 1 in the intestinal mucosa
-
Meng G, Sellers MT, Mosteller-Barnum M, et al. Lamina propria lymphocytes, not macrophages, express CCR5 and CXCR4 and are the likely target cell for human immunodeficiency virus type 1 in the intestinal mucosa. J Infect Dis 2000; 182:785-791.
-
(2000)
J Infect Dis
, vol.182
, pp. 785-791
-
-
Meng, G.1
Sellers, M.T.2
Mosteller-Barnum, M.3
-
15
-
-
0742325043
-
The CCR5 and CXCR4 coreceptors- central to understanding the transmission and pathogenesis of human immunodeficiency virus type 1 infection
-
Moore JP, Kitchen SG, Pugach P, Zack JA. The CCR5 and CXCR4 coreceptors- central to understanding the transmission and pathogenesis of human immunodeficiency virus type 1 infection. AIDS Res Hum Retroviruses 2004; 20:111-126.
-
(2004)
AIDS Res Hum Retroviruses
, vol.20
, pp. 111-126
-
-
Moore, J.P.1
Kitchen, S.G.2
Pugach, P.3
Zack, J.A.4
-
16
-
-
37349009949
-
HIV-1 X4/R5 co-receptor in viral reservoir during suppressive HAART
-
Soulie C, Marcelin AG, Ghosn J, et al. HIV-1 X4/R5 co-receptor in viral reservoir during suppressive HAART. AIDS 2007; 21:2243-2245.
-
(2007)
AIDS
, vol.21
, pp. 2243-2245
-
-
Soulie, C.1
Marcelin, A.G.2
Ghosn, J.3
-
17
-
-
15044339793
-
R5 to X4 switch of the predominant HIV-1 population in cellular reservoirs during effective highly active antiretroviral therapy
-
Delobel P, Sandres-Saune K, Cazabat M, et al. R5 to X4 switch of the predominant HIV-1 population in cellular reservoirs during effective highly active antiretroviral therapy. J Acquir Immune Defic Syndr 2005; 38:382- 392.
-
(2005)
J Acquir Immune Defic Syndr
, vol.38
, pp. 382-392
-
-
Delobel, P.1
Sandres-Saune, K.2
Cazabat, M.3
-
18
-
-
67249147641
-
High frequency of X4/DM-tropic viruses in PBMC samples from patients with primary hiv-1 subtype-b infection in 1996-2007: The french anrs co06 primo cohort study
-
Frange P, Galimand J, Goujard C, et al. High frequency of X4/DM-tropic viruses in PBMC samples from patients with primary HIV-1 subtype-B infection in 1996-2007: The French ANRS CO06 PRIMO Cohort Study. J Antimicrob Chemother 2009; 64:135-141.
-
(2009)
J Antimicrob Chemother
, vol.64
, pp. 135-141
-
-
Frange, P.1
Galimand, J.2
Goujard, C.3
-
19
-
-
77957225590
-
HIV genetic diversity between plasma and cerebrospinal fluid in patients with HIV encephalitis
-
Soulie C, Fourati S, Lambert-Niclot S, et al. HIV genetic diversity between plasma and cerebrospinal fluid in patients with HIV encephalitis. AIDS 2010; 24:2412-2414.
-
(2010)
AIDS
, vol.24
, pp. 2412-2414
-
-
Soulie, C.1
Fourati, S.2
Lambert-Niclot, S.3
-
20
-
-
79951513841
-
Low frequency of HIV-1 tropism evolution in patients successfully treated for at least 2 years
-
Soulie C, Lambert-Niclot S, Wirden M, et al. Low frequency of HIV-1 tropism evolution in patients successfully treated for at least 2 years. AIDS 2011; 25:537-539.
-
(2011)
AIDS
, vol.25
, pp. 537-539
-
-
Soulie, C.1
Lambert-Niclot, S.2
Wirden, M.3
-
22
-
-
77957223314
-
CXCR4-using viruses in plasma and peripheral blood mononuclear cells during primary HIV-1 infection and impact on disease progression
-
Raymond S, Delobel P, Mavigner M, et al. CXCR4-using viruses in plasma and peripheral blood mononuclear cells during primary HIV-1 infection and impact on disease progression. AIDS 2010; 24:2305-2312.
-
(2010)
AIDS
, vol.24
, pp. 2305-2312
-
-
Raymond, S.1
Delobel, P.2
Mavigner, M.3
-
23
-
-
79959836577
-
Genotypic prediction of human immunodeficiency virus type 1 tropism by use of plasma and peripheral blood mononuclear cells in the routine clinical laboratory
-
Paar C, Geit M, Stekel H, Berg J. Genotypic prediction of human immunodeficiency virus type 1 tropism by use of plasma and peripheral blood mononuclear cells in the routine clinical laboratory. J Clin Microbiol 2011; 49:2697-2699.
-
(2011)
J Clin Microbiol
, vol.49
, pp. 2697-2699
-
-
Paar, C.1
Geit, M.2
Stekel, H.3
Berg, J.4
-
25
-
-
80053386322
-
Concordance between HIV-1 genotypic coreceptor tropism predictions based on plasma RNA and proviral DNA
-
This study demonstrated highly concordant troism redictions for roviral DNA and lasma RNA offering a romising aroach for troism rediction in clinical ractice
-
Verhofstede C, Brudney D, Reynaerts J, et al. Concordance between HIV-1 genotypic coreceptor tropism predictions based on plasma RNA and proviral DNA. HIV Med 2011; 12:544-552. This study demonstrated highly concordant tropism predictions for proviral DNA and plasma RNA offering a promising approach for tropism prediction in clinical practice.
-
(2011)
HIV Med
, vol.12
, pp. 544-552
-
-
Verhofstede, C.1
Brudney, D.2
Reynaerts, J.3
-
26
-
-
60749113438
-
CXCR4-using HIV type 1 variants are more commonly found in peripheral blood mononuclear cell DNA than in plasma RNA
-
Verhofstede C, Vandekerckhove L, Eygen VV, et al. CXCR4-using HIV type 1 variants are more commonly found in peripheral blood mononuclear cell DNA than in plasma RNA. J Acquir Immune Defic Syndr 2009; 50:126-136.
-
(2009)
J Acquir Immune Defic Syndr
, vol.50
, pp. 126-136
-
-
Verhofstede, C.1
Vandekerckhove, L.2
Eygen, V.V.3
-
27
-
-
79953891689
-
Analysis of co-receptor usage of circulating viral and proviral HIV genome quasispecies by ultra-deep pyrosequencing in patients who are candidates for CCR5 antagonist treatment
-
Abbate I, Rozera G, Tommasi C, et al. Analysis of co-receptor usage of circulating viral and proviral HIV genome quasispecies by ultra-deep pyrosequencing in patients who are candidates for CCR5 antagonist treatment. Clin Microbiol Infect 2011; 17:725-731.
-
(2011)
Clin Microbiol Infect
, vol.17
, pp. 725-731
-
-
Abbate, I.1
Rozera, G.2
Tommasi, C.3
-
29
-
-
34249992110
-
Prevalence of X4 tropic viruses in patients recently infected with HIV-1 and lack of association with transmission of drug resistance
-
de Mendoza C, Rodriguez C, Garcia F, et al. Prevalence of X4 tropic viruses in patients recently infected with HIV-1 and lack of association with transmission of drug resistance. J Antimicrob Chemother 2007; 59:698-704.
-
(2007)
J Antimicrob Chemother
, vol.59
, pp. 698-704
-
-
De Mendoza, C.1
Rodriguez, C.2
Garcia, F.3
-
30
-
-
14844333093
-
Epidemiology and predictive factors for chemokine receptor use in HIV-1 infection
-
Moyle GJ, Wildfire A, Mandalia S, et al. Epidemiology and predictive factors for chemokine receptor use in HIV-1 infection. J Infect Dis 2005; 191:866- 872.
-
(2005)
J Infect Dis
, vol.191
, pp. 866-872
-
-
Moyle, G.J.1
Wildfire, A.2
Mandalia, S.3
-
31
-
-
22544456536
-
Molecular and clinical epidemiology of CXCR4-using HIV-1 in a large population of antiretroviral-naive individuals
-
Brumme ZL, Goodrich J, Mayer HB, et al. Molecular and clinical epidemiology of CXCR4-using HIV-1 in a large population of antiretroviral-naive individuals. J Infect Dis 2005; 192:466-474.
-
(2005)
J Infect Dis
, vol.192
, pp. 466-474
-
-
Brumme, Z.L.1
Goodrich, J.2
Mayer, H.B.3
-
32
-
-
33749039498
-
Prevalence of CXCR4 tropism among antiretroviral-treated HIV-1-infected patients with detectable viremia
-
Hunt PW, Harrigan PR, Huang W, et al. Prevalence of CXCR4 tropism among antiretroviral-treated HIV-1-infected patients with detectable viremia. J Infect Dis 2006; 194:926-930.
-
(2006)
J Infect Dis
, vol.194
, pp. 926-930
-
-
Hunt, P.W.1
Harrigan, P.R.2
Huang, W.3
-
33
-
-
34347361504
-
Prevalence of X4 tropic HIV-1 variants in patients with differences in disease stage and exposure to antiretroviral therapy
-
Poveda E, Briz V, de Mendoza C, et al. Prevalence of X4 tropic HIV-1 variants in patients with differences in disease stage and exposure to antiretroviral therapy. J Med Virol 2007; 79:1040-1046.
-
(2007)
J Med Virol
, vol.79
, pp. 1040-1046
-
-
Poveda, E.1
Briz, V.2
De Mendoza, C.3
-
34
-
-
33846932573
-
HIV type 1 chemokine coreceptor use among antiretroviral-experienced patients screened for a clinical trial of A CCR5 Inhibitor AIDS Clinical Trial Group A5211
-
Wilkin TJ Su Z Kuritzkes DR et al. HIV type 1 chemokine coreceptor use among antiretroviral-experienced patients screened for a clinical trial of A CCR5 Inhibitor AIDS Clinical Trial Group A5211. Clin Infect Dis 2007; 44591-595.
-
(2007)
Clin Infect Dis
, vol.44
, pp. 591-595
-
-
Wilkin, T.J.1
Su, Z.2
Kuritzkes, D.R.3
-
35
-
-
0036440563
-
Evolution of total and integrated HIV-1 DNA and change in DNA sequences in patients with sustained plasma virus suppression
-
Izopet J, Cazabat M, Pasquier C, et al. Evolution of total and integrated HIV-1 DNA and change in DNA sequences in patients with sustained plasma virus suppression. Virology 2002; 302:393-404.
-
(2002)
Virology
, vol.302
, pp. 393-404
-
-
Izopet, J.1
Cazabat, M.2
Pasquier, C.3
-
36
-
-
0030868897
-
Positive effects of combined antiretroviral therapy on CD4 T cell homeostasis and function in advanced HIV disease
-
Autran B, Carcelain G, Li TS, et al. Positive effects of combined antiretroviral therapy on CD4 T cell homeostasis and function in advanced HIV disease. Science 1997; 277:112-116.
-
(1997)
Science
, vol.277
, pp. 112-116
-
-
Autran, B.1
Carcelain, G.2
Li, T.S.3
-
37
-
-
0033961745
-
In vivo HIV-1 infection of CD45RACD4 T cells is established primarily by syncytium-inducing variants and correlates with the rate of CD4() T cell decline
-
Blaak H, van 't Wout AB, Brouwer M, et al. In vivo HIV-1 infection of CD45RACD4 T cells is established primarily by syncytium-inducing variants and correlates with the rate of CD4 T cell decline. Proc Natl Acad Sci U S A 2000; 97:1269-1274.
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 1269-1274
-
-
Blaak, H.1
Van 't Wout, A.B.2
Brouwer, M.3
-
38
-
-
0032775436
-
Both memory and CD45RA/ CD62L naive CD4 T cells are infected in human immunodeficiency virus type 1-infected individuals
-
Ostrowski MA, Chun TW, Justement SJ, et al. Both memory and CD45RA/ CD62L naive CD4 T cells are infected in human immunodeficiency virus type 1-infected individuals. J Virol 1999; 73:6430-6435.
-
(1999)
J Virol
, vol.73
, pp. 6430-6435
-
-
Ostrowski, M.A.1
Chun, T.W.2
Justement, S.J.3
-
39
-
-
0035114185
-
Preferential suppression of CXCR4- specific strains of HIV-1 by antiviral therapy
-
Philpott S, Weiser B, Anastos K, et al. Preferential suppression of CXCR4- specific strains of HIV-1 by antiviral therapy. J Clin Invest 2001; 107:431- 438.
-
(2001)
J Clin Invest
, vol.107
, pp. 431-438
-
-
Philpott, S.1
Weiser, B.2
Anastos, K.3
-
40
-
-
0033827618
-
Recovery of replication-competent virus from CD4 T cell reservoirs and change in coreceptor use in human immunodeficiency virus type 1-infected children responding to highly active antiretroviral therapy
-
Equils O, Garratty E, Wei LS, et al. Recovery of replication-competent virus from CD4 T cell reservoirs and change in coreceptor use in human immunodeficiency virus type 1-infected children responding to highly active antiretroviral therapy. J Infect Dis 2000; 182:751-757.
-
(2000)
J Infect Dis
, vol.182
, pp. 751-757
-
-
Equils, O.1
Garratty, E.2
Wei, L.S.3
-
41
-
-
0037964387
-
Impact of antiretroviral treatment on the tropism of HIV-1 plasma virus populations
-
Skrabal K, Trouplin V, Labrosse B, et al. Impact of antiretroviral treatment on the tropism of HIV-1 plasma virus populations. AIDS 2003; 17:809- 814.
-
(2003)
AIDS
, vol.17
, pp. 809-814
-
-
Skrabal, K.1
Trouplin, V.2
Labrosse, B.3
-
42
-
-
70449411747
-
HIV-1 residual viremia correlates with persistent T-cell activation in poor immunological responders to combination antiretroviral therapy
-
Mavigner M, Delobel P, Cazabat M, et al. HIV-1 residual viremia correlates with persistent T-cell activation in poor immunological responders to combination antiretroviral therapy. PLoS One 2009; 4:e7658.
-
(2009)
Plos One
, vol.4
-
-
Mavigner, M.1
Delobel, P.2
Cazabat, M.3
-
43
-
-
0038805436
-
High frequency of syncytiuminducing and CXCR4-tropic viruses among human immunodeficiency virus type 1 subtype C-infected patients receiving antiretroviral treatment
-
Johnston ER, Zijenah LS, Mutetwa S, et al. High frequency of syncytiuminducing and CXCR4-tropic viruses among human immunodeficiency virus type 1 subtype C-infected patients receiving antiretroviral treatment. J Virol2003; 77:7682-7688.
-
(2003)
J Virol
, vol.77
, pp. 7682-7688
-
-
Johnston, E.R.1
Zijenah, L.S.2
Mutetwa, S.3
-
44
-
-
10744219648
-
Virological phenotype switches under salvage therapy with lopinavir-ritonavir in heavily pretreated HIV-1 vertically infected children
-
Galan I, Jimenez JL, Gonzalez-Rivera M, et al. Virological phenotype switches under salvage therapy with lopinavir-ritonavir in heavily pretreated HIV-1 vertically infected children. AIDS 2004; 18:247-255.
-
(2004)
AIDS
, vol.18
, pp. 247-255
-
-
Galan, I.1
Jimenez, J.L.2
Gonzalez-Rivera, M.3
-
45
-
-
33749491636
-
Naive T-cell depletion related to infection by X4 human immunodeficiency virus type 1 in poor immunological responders to highly active antiretroviral therapy
-
Delobel P, Nugeyre MT, Cazabat M, et al. Naive T-cell depletion related to infection by X4 human immunodeficiency virus type 1 in poor immunological responders to highly active antiretroviral therapy. J Virol 2006; 80:10229- 10236.
-
(2006)
J Virol
, vol.80
, pp. 10229-10236
-
-
Delobel, P.1
Nugeyre, M.T.2
Cazabat, M.3
-
46
-
-
0038579210
-
Long-term follow-up studies confirm the stability of the latent reservoir for HIV-1 in resting CD4 T cells
-
Siliciano JD, Kajdas J, Finzi D, et al. Long-term follow-up studies confirm the stability of the latent reservoir for HIV-1 in resting CD4 T cells. Nat Med 2003; 9:727-728.
-
(2003)
Nat Med
, vol.9
, pp. 727-728
-
-
Siliciano, J.D.1
Kajdas, J.2
Finzi, D.3
-
47
-
-
0033613342
-
Re-emergence of HIV after stopping therapy
-
Chun TW, Davey RT Jr, Engel D, et al. Re-emergence of HIV after stopping therapy. Nature 1999; 401:874-875.
-
(1999)
Nature
, vol.401
, pp. 874-875
-
-
Chun, T.W.1
Davey Jr., R.T.2
Engel, D.3
-
48
-
-
9144261631
-
T-cell subsets that harbor human immunodeficiency virus (HIV) in vivo: Implications for HIV pathogenesis
-
Brenchley JM, Hill BJ, Ambrozak DR, et al. T-cell subsets that harbor human immunodeficiency virus (HIV) in vivo: Implications for HIV pathogenesis. J Virol 2004; 78:1160-1168.
-
(2004)
J Virol
, vol.78
, pp. 1160-1168
-
-
Brenchley, J.M.1
Hill, B.J.2
Ambrozak, D.R.3
-
49
-
-
0032555117
-
Early establishment of a pool of latently infected, resting CD4 T cells during primary HIV-1 infection
-
Chun TW, Engel D, Berrey MM, et al. Early establishment of a pool of latently infected, resting CD4 T cells during primary HIV-1 infection. Proc Natl Acad Sci U S A 1998; 95:8869-8873.
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 8869-8873
-
-
Chun, T.W.1
Engel, D.2
Berrey, M.M.3
-
50
-
-
0030659177
-
Presence of an inducible HIV-1 latent reservoir during highly active antiretroviral therapy
-
Chun TW, Stuyver L, Mizell SB, et al. Presence of an inducible HIV-1 latent reservoir during highly active antiretroviral therapy. Proc Natl Acad Sci U S A 1997; 94:13193-13197.
-
(1997)
Proc Natl Acad Sci U S
, vol.94
, pp. 13193-13197
-
-
Chun, T.W.1
Stuyver, L.2
Mizell, S.B.3
-
51
-
-
0032953920
-
Latent infection of CD4 T cells provides a mechanism for lifelong persistence of HIV-1, even in patients on effective combination therapy
-
Finzi D, Blankson J, Siliciano JD, et al. Latent infection of CD4 T cells provides a mechanism for lifelong persistence of HIV-1, even in patients on effective combination therapy. Nat Med 1999; 5:512-517.
-
(1999)
Nat Med
, vol.5
, pp. 512-517
-
-
Finzi, D.1
Blankson, J.2
Siliciano, J.D.3
-
52
-
-
14444273439
-
Identification of a reservoir for HIV-1 in patients on highly active antiretroviral therapy
-
Finzi D, Hermankova M, Pierson T, et al. Identification of a reservoir for HIV-1 in patients on highly active antiretroviral therapy. Science 1997; 278:1295- 1300.
-
(1997)
Science
, vol.278
, pp. 1295-1300
-
-
Finzi, D.1
Hermankova, M.2
Pierson, T.3
-
53
-
-
0030712305
-
Recovery of replication-competent HIV despite prolonged suppression of plasma viremia
-
Wong JK, Hezareh M, Gunthard HF, et al. Recovery of replication-competent HIV despite prolonged suppression of plasma viremia. Science 1997; 278:1291-1295.
-
(1997)
Science
, vol.278
, pp. 1291-1295
-
-
Wong, J.K.1
Hezareh, M.2
Gunthard, H.F.3
-
54
-
-
15244359120
-
Differential evolution of cell-associated virus in blood and genital tract of HIV-infected females undergoing HAART
-
Tirado G, Jove G, Reyes E, et al. Differential evolution of cell-associated virus in blood and genital tract of HIV-infected females undergoing HAART. Virology 2005; 334:299-305.
-
(2005)
Virology
, vol.334
, pp. 299-305
-
-
Tirado, G.1
Jove, G.2
Reyes, E.3
-
55
-
-
10644234595
-
Human immunodeficiency virus type 1 genomic RNA sequences in the female genital tract and blood: Compartmentalization and intrapatient recombination
-
Philpott S, Burger H, Tsoukas C, et al. Human immunodeficiency virus type 1 genomic RNA sequences in the female genital tract and blood: Compartmentalization and intrapatient recombination. J Virol 2005; 79:353- 363.
-
(2005)
J Virol
, vol.79
, pp. 353-363
-
-
Philpott, S.1
Burger, H.2
Tsoukas, C.3
-
56
-
-
0034796289
-
Macrophage tropism of human immunodeficiency virus type 1 isolates from brain and lymphoid tissues predicts neurotropism independent of coreceptor specificity
-
Gorry PR, Bristol G, Zack JA, et al. Macrophage tropism of human immunodeficiency virus type 1 isolates from brain and lymphoid tissues predicts neurotropism independent of coreceptor specificity. J Virol 2001; 75:10073-10089.
-
(2001)
J Virol
, vol.75
, pp. 10073-10089
-
-
Gorry, P.R.1
Bristol, G.2
Zack, J.A.3
-
57
-
-
0036114281
-
Increased CCR5 affinity and reduced CCR5/CD4 dependence of a neurovirulent primary human immunodeficiency virus type 1 isolate
-
Gorry PR, Taylor J, Holm GH, et al. Increased CCR5 affinity and reduced CCR5/CD4 dependence of a neurovirulent primary human immunodeficiency virus type 1 isolate. J Virol 2002; 76:6277-6292.
-
(2002)
J Virol
, vol.76
, pp. 6277-6292
-
-
Gorry, P.R.1
Taylor, J.2
Holm, G.H.3
-
58
-
-
2942687021
-
Biological analysis of human immunodeficiency virus type 1 R5 envelopes amplified from brain and lymph node tissues of AIDS patients with neuropathology reveals two distinct tropism phenotypes and identifies envelopes in the brain that confer an enhanced tropism and fusogenicity for macrophages
-
Peters PJ, Bhattacharya J, Hibbitts S, et al. Biological analysis of human immunodeficiency virus type 1 R5 envelopes amplified from brain and lymph node tissues of AIDS patients with neuropathology reveals two distinct tropism phenotypes and identifies envelopes in the brain that confer an enhanced tropism and fusogenicity for macrophages. J Virol 2004; 78:6915-6926.
-
(2004)
J Virol
, vol.78
, pp. 6915-6926
-
-
Peters, P.J.1
Bhattacharya, J.2
Hibbitts, S.3
-
60
-
-
0032889037
-
Microglia express CCR5, CXCR4, and CCR3, but of these, CCR5 is the principal coreceptor for human immunodeficiency virus type 1 dementia isolates
-
Albright AV, Shieh JT, Itoh T, et al. Microglia express CCR5, CXCR4, and CCR3, but of these, CCR5 is the principal coreceptor for human immunodeficiency virus type 1 dementia isolates. J Virol 1999; 73:205-213.
-
(1999)
J Virol
, vol.73
, pp. 205-213
-
-
Albright, A.V.1
Shieh, J.T.2
Itoh, T.3
-
61
-
-
19244380883
-
CCR3 and CCR5 are co-receptors for HIV-1 infection of microglia
-
He J, Chen Y, Farzan M, et al. CCR3 and CCR5 are co-receptors for HIV-1 infection of microglia. Nature 1997; 385:645-649.
-
(1997)
Nature
, vol.385
, pp. 645-649
-
-
He, J.1
Chen, Y.2
Farzan, M.3
-
62
-
-
0032731642
-
Persistent CCR5 utilization and enhanced macrophage tropism by primary blood human immunodeficiency virus type 1 isolates from advanced stages of disease and comparison to tissue- derived isolates
-
Li S, Juarez J, Alali M, et al. Persistent CCR5 utilization and enhanced macrophage tropism by primary blood human immunodeficiency virus type 1 isolates from advanced stages of disease and comparison to tissue- derived isolates. J Virol 1999; 73:9741-9755.
-
(1999)
J Virol
, vol.73
, pp. 9741-9755
-
-
Li, S.1
Juarez, J.2
Alali, M.3
-
63
-
-
67651181012
-
Presence of HIV-1 R5 viruses in cerebrospinal fluid even in patients harboring R5X4/X4 viruses in plasma
-
Soulie C, Tubiana R, Simon A, et al. Presence of HIV-1 R5 viruses in cerebrospinal fluid even in patients harboring R5X4/X4 viruses in plasma. J Acquir Immune Defic Syndr 2009; 51:60-64.
-
(2009)
J Acquir Immune Defic Syndr
, vol.51
, pp. 60-64
-
-
Soulie, C.1
Tubiana, R.2
Simon, A.3
-
64
-
-
15844419153
-
Identification of a major co-receptor for primary isolates of HIV-1
-
Deng H, Liu R, Ellmeier W, et al. Identification of a major co-receptor for primary isolates of HIV-1. Nature 1996; 381:661-666.
-
(1996)
Nature
, vol.381
, pp. 661-666
-
-
Deng, H.1
Liu, R.2
Ellmeier, W.3
-
65
-
-
15844389650
-
HIV-1 entry into CD4 cells is mediated by the chemokine receptor CC-CKR-5
-
Dragic T, Litwin V, Allaway GP, et al. HIV-1 entry into CD4 cells is mediated by the chemokine receptor CC-CKR-5. Nature 1996; 381:667-673.
-
(1996)
Nature
, vol.381
, pp. 667-673
-
-
Dragic, T.1
Litwin, V.2
Allaway, G.P.3
-
66
-
-
0032933836
-
Apoptosis induced by infection of primary brain cultures with diverse human immunodeficiency virus type 1 isolates: Evidence for a role of the envelope
-
Ohagen A, Ghosh S, He J, et al. Apoptosis induced by infection of primary brain cultures with diverse human immunodeficiency virus type 1 isolates: Evidence for a role of the envelope. J Virol 1999; 73:897-906.
-
(1999)
J Virol
, vol.73
, pp. 897-906
-
-
Ohagen, A.1
Ghosh, S.2
He, J.3
-
67
-
-
0034701034
-
Cerebrospinal fluid HIV RNA originates from both local CNS and systemic sources
-
Ellis RJ, Gamst AC, Capparelli E, et al. Cerebrospinal fluid HIV RNA originates from both local CNS and systemic sources. Neurology 2000; 54:927- 936.
-
(2000)
Neurology
, vol.54
, pp. 927-936
-
-
Ellis, R.J.1
Gamst, A.C.2
Capparelli, E.3
-
68
-
-
0034633729
-
Evidence of a source of HIV type 1 within the central nervous system by ultraintensive sampling of cerebrospinal fluid and plasma
-
Haas DW, Clough LA, Johnson BW, et al. Evidence of a source of HIV type 1 within the central nervous system by ultraintensive sampling of cerebrospinal fluid and plasma. AIDS Res Hum Retroviruses 2000;16:1491-1502.
-
(2000)
AIDS Res Hum Retroviruses
, vol.16
, pp. 1491-1502
-
-
Haas, D.W.1
Clough, L.A.2
Johnson, B.W.3
-
69
-
-
79953865871
-
HIV coreceptor tropism in paired plasma, peripheral blood mononuclear cell, and cerebrospinal fluid isolates from antiretroviral-naive subjects
-
The HIV tropism in cerebrospinal fluid was mainly R5 for antiretroviral-naíve patients
-
Parisi SG, Andreoni C, Sarmati L, et al. HIV coreceptor tropism in paired plasma, peripheral blood mononuclear cell, and cerebrospinal fluid isolates from antiretroviral-naive subjects. J Clin Microbiol 2011; 49:1441- 1445.The HIV tropism in cerebrospinal fluid was mainly R5 for antiretroviral-naíve patients.
-
(2011)
J Clin Microbiol
, vol.49
, pp. 1441-1445
-
-
Parisi, S.G.1
Andreoni, C.2
Sarmati, L.3
-
70
-
-
0029976629
-
Cloning functional characterization of novel dopamine receptor from drosophila melanogaster
-
Feng G Hannan F Reale V et al. Cloning functional characterization of a Novel Dopamine Receptor From Drosophila Melanogaster. J Neurosci 1996; 163925-3933.
-
(1996)
J Neurosci
, vol.16
, pp. 3925-3933
-
-
Feng, G.1
Hannan, F.2
Reale, V.3
-
71
-
-
0242331608
-
HIV-1 in genital tract and plasma of women: Compartmentalization of viral sequences, coreceptor usage, and glycosylation
-
Kemal KS, Foley B, Burger H, et al. HIV-1 in genital tract and plasma of women: Compartmentalization of viral sequences, coreceptor usage, and glycosylation. Proc Natl Acad Sci U S A 2003; 100:12972-12977.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 12972-12977
-
-
Kemal, K.S.1
Foley, B.2
Burger, H.3
-
72
-
-
0035400159
-
Cellular replication of human immunodeficiency virus type 1 occurs in vaginal secretions
-
Ellerbrock TV, Lennox JL, Clancy KA, et al. Cellular replication of human immunodeficiency virus type 1 occurs in vaginal secretions. J Infect Dis 2001; 184:28-36.
-
(2001)
J Infect Dis
, vol.184
, pp. 28-36
-
-
Ellerbrock, T.V.1
Lennox, J.L.2
Clancy, K.A.3
-
73
-
-
22544479140
-
Diversity, divergence, and evolution of cell-free human immunodeficiency virus type 1 in vaginal secretions and blood of chronically infected women: Associations with immune status
-
Sullivan ST, Mandava U, Evans-Strickfaden T, et al. Diversity, divergence, and evolution of cell-free human immunodeficiency virus type 1 in vaginal secretions and blood of chronically infected women: Associations with immune status. J Virol 2005; 79:9799-9809.
-
(2005)
J Virol
, vol.79
, pp. 9799-9809
-
-
Sullivan, S.T.1
Mandava, U.2
Evans-Strickfaden, T.3
-
74
-
-
34250658868
-
Genetic and phenotypic features of blood and genital viral populations of clinically asymptomatic and antiretroviral- treatment-naive clade a human immunodeficiency virus type 1-infected women
-
Andreoletti L, Skrabal K, Perrin V, et al. Genetic and phenotypic features of blood and genital viral populations of clinically asymptomatic and antiretroviral- treatment-naive clade a human immunodeficiency virus type 1-infected women. J Clin Microbiol 2007; 45:1838-1842.
-
(2007)
J Clin Microbiol
, vol.45
, pp. 1838-1842
-
-
Andreoletti, L.1
Skrabal, K.2
Perrin, V.3
-
75
-
-
0031694637
-
Evolution of envelope sequences from the genital tract and peripheral blood of women infected with clade A human immunodeficiency virus type 1
-
Poss M, Rodrigo AG, Gosink JJ, et al. Evolution of envelope sequences from the genital tract and peripheral blood of women infected with clade A human immunodeficiency virus type 1. J Virol 1998; 72:8240-8251.
-
(1998)
J Virol
, vol.72
, pp. 8240-8251
-
-
Poss, M.1
Rodrigo, A.G.2
Gosink, J.J.3
-
76
-
-
0029998895
-
Genetic characterization of human immunodeficiency virus type 1 in blood and genital secretions: Evidence for viral compartmentalization and selection during sexual transmission
-
Zhu T, Wang N, Carr A, et al. Genetic characterization of human immunodeficiency virus type 1 in blood and genital secretions: Evidence for viral compartmentalization and selection during sexual transmission. J Virol 1996; 70:3098-3107.
-
(1996)
J Virol
, vol.70
, pp. 3098-3107
-
-
Zhu, T.1
Wang, N.2
Carr, A.3
-
77
-
-
0030773745
-
Identification of homing receptors that mediate the recruitment of CD4 T cells to the genital tract following intravaginal infection with Chlamydia trachomatis
-
Kelly KA, Rank RG. Identification of homing receptors that mediate the recruitment of CD4 T cells to the genital tract following intravaginal infection with Chlamydia trachomatis. Infect Immun 1997; 65:5198-5208.
-
(1997)
Infect Immun
, vol.65
, pp. 5198-5208
-
-
Kelly, K.A.1
Rank, R.G.2
-
78
-
-
79951920271
-
CXCR3 and CCR5 are both required for T cell-mediated protection against C. trachomatis infection in the murine genital mucosa
-
Olive AJ, Gondek DC, Starnbach MN. CXCR3 and CCR5 are both required for T cell-mediated protection against C. trachomatis infection in the murine genital mucosa. Mucosal Immunol 2011; 4:208-216.
-
(2011)
Mucosal Immunol
, vol.4
, pp. 208-216
-
-
Olive, A.J.1
Gondek, D.C.2
Starnbach, M.N.3
-
79
-
-
0026695382
-
HIV-1 genomic RNA diversification following sexual and parenteral virus transmission
-
Wolfs TF, Zwart G, Bakker M, Goudsmit J. HIV-1 genomic RNA diversification following sexual and parenteral virus transmission. Virology 1992; 189:103- 110.
-
(1992)
Virology
, vol.189
, pp. 103-110
-
-
Wolfs, T.F.1
Zwart, G.2
Bakker, M.3
Goudsmit, J.4
-
80
-
-
0027422278
-
Genotypic and phenotypic characterization of HIV-1 patients with primary infection
-
Zhu T, Mo H, Wang N, et al. Genotypic and phenotypic characterization of HIV-1 patients with primary infection. Science 1993; 261:1179-1181.
-
(1993)
Science
, vol.261
, pp. 1179-1181
-
-
Zhu, T.1
Mo, H.2
Wang, N.3
-
81
-
-
0028091755
-
Macrophage-tropic variants initiate human immunodeficiency virus type 1 infection after sexual, parenteral, and vertical transmission
-
van 't Wout AB, Kootstra NA, Mulder-Kampinga GA, et al. Macrophage-tropic variants initiate human immunodeficiency virus type 1 infection after sexual, parenteral, and vertical transmission. J Clin Invest 1994; 94:2060-2067.
-
(1994)
J Clin Invest
, vol.94
, pp. 2060-2067
-
-
Van 't Wout, A.B.1
Kootstra, N.A.2
Mulder-Kampinga, G.A.3
-
82
-
-
0033567102
-
Coexpression of CCR5 and IL-2 in human genital but not blood T cells: Implications for the ontogeny of the CCR5 Th1 phenotype
-
Hladik F, Lentz G, Delpit E, et al. Coexpression of CCR5 and IL-2 in human genital but not blood T cells: Implications for the ontogeny of the CCR5 Th1 phenotype. J Immunol 1999; 163:2306-2313.
-
(1999)
J Immunol
, vol.163
, pp. 2306-2313
-
-
Hladik, F.1
Lentz, G.2
Delpit, E.3
-
83
-
-
0032540418
-
Gastrointestinal tract as a major site of CD4 T cell depletion and viral replication in SIV infection
-
Veazey RS, DeMaria M, Chalifoux LV, et al. Gastrointestinal tract as a major site of CD4 T cell depletion and viral replication in SIV infection. Science1998; 280:427-431.
-
(1998)
Science
, vol.280
, pp. 427-431
-
-
Veazey, R.S.1
DeMaria, M.2
Chalifoux, L.V.3
-
84
-
-
0142092389
-
Severe CD4 T-cell depletion in gut lymphoid tissue during primary human immunodeficiency virus type 1 infection and substantial delay in restoration following highly active antiretroviral therapy
-
Guadalupe M, Reay E, Sankaran S, et al. Severe CD4 T-cell depletion in gut lymphoid tissue during primary human immunodeficiency virus type 1 infection and substantial delay in restoration following highly active antiretroviral therapy. J Virol 2003; 77:11708-11717.
-
(2003)
J Virol
, vol.77
, pp. 11708-11717
-
-
Guadalupe, M.1
Reay, E.2
Sankaran, S.3
-
85
-
-
0033827042
-
Enhanced levels of functional HIV-1 coreceptors on human mucosal T cells demonstrated using intestinal biopsy tissue
-
Anton PA, Elliott J, Poles MA, et al. Enhanced levels of functional HIV-1 coreceptors on human mucosal T cells demonstrated using intestinal biopsy tissue. AIDS 2000; 14:1761-1765.
-
(2000)
AIDS
, vol.14
, pp. 1761-1765
-
-
Anton, P.A.1
Elliott, J.2
Poles, M.A.3
-
86
-
-
0034888099
-
A preponderance of CCR5() CXCR4() mononuclear cells enhances gastrointestinal mucosal susceptibility to human immunodeficiency virus type 1 infection
-
Poles MA, Elliott J, Taing P, et al. A preponderance of CCR5() CXCR4() mononuclear cells enhances gastrointestinal mucosal susceptibility to human immunodeficiency virus type 1 infection. J Virol 2001; 75:8390-8399.
-
(2001)
J Virol
, vol.75
, pp. 8390-8399
-
-
Poles, M.A.1
Elliott, J.2
Taing, P.3
-
87
-
-
0033715824
-
Human immunodeficiency virus type 1 infection is associated with significant mucosal inflammation characterized by increased expression of CCR5, CXCR4, and beta-chemokines
-
Olsson J, Poles M, Spetz AL, et al. Human immunodeficiency virus type 1 infection is associated with significant mucosal inflammation characterized by increased expression of CCR5, CXCR4, and beta-chemokines. J Infect Dis 2000; 182:1625-1635.
-
(2000)
J Infect Dis
, vol.182
, pp. 1625-1635
-
-
Olsson, J.1
Poles, M.2
Spetz, A.L.3
-
88
-
-
38849095682
-
Compartmentalization of the gut viral reservoir in HIV-1 infected patients
-
van Marle G, Gill MJ, Kolodka D, et al. Compartmentalization of the gut viral reservoir in HIV-1 infected patients. Retrovirology 2007; 4:87.
-
(2007)
Retrovirology
, vol.4
, pp. 87
-
-
Van Marle, G.1
Gill, M.J.2
Kolodka, D.3
-
89
-
-
40549092339
-
Persistence of HIV in gut-associated lymphoid tissue despite long-term antiretroviral therapy
-
Chun TW, Nickle DC, Justement JS, et al. Persistence of HIV in gut-associated lymphoid tissue despite long-term antiretroviral therapy. J Infect Dis 2008; 197:714-720.
-
(2008)
J Infect Dis
, vol.197
, pp. 714-720
-
-
Chun, T.W.1
Nickle, D.C.2
Justement, J.S.3
-
90
-
-
79958717142
-
Lack of compartmentalization of HIV-1 quasispecies between the gut and peripheral blood compartments
-
Imamichi H, Degray G, Dewar RL, et al. Lack of compartmentalization of HIV-1 quasispecies between the gut and peripheral blood compartments. J Infect Dis 2011; 204:309-314.
-
(2011)
J Infect Dis
, vol.204
, pp. 309-314
-
-
Imamichi, H.1
Degray, G.2
Dewar, R.L.3
-
91
-
-
0022668345
-
-
This study provided evidence of ongoing virus production in the gut and equilibrium of HIV between the gut and peripheral blood compartments.88. Fels AO, Cohn ZA. The alveolar macrophage
-
This study provided evidence of ongoing virus production in the gut and equilibrium of HIV between the gut and peripheral blood compartments. 88. Fels AO, Cohn ZA. The alveolar macrophage. J Appl Physiol 1986; 60:353- 369.
-
(1986)
J Appl Physiol
, vol.60
, pp. 353-369
-
-
-
92
-
-
0028028403
-
Human immunodeficiency virus type 1 strains in the lungs of infected individuals evolve independently from those in peripheral blood and are highly conserved in the C-terminal region of the envelope V3 loop
-
Itescu S, Simonelli PF, Winchester RJ, Ginsberg HS. Human immunodeficiency virus type 1 strains in the lungs of infected individuals evolve independently from those in peripheral blood and are highly conserved in the C-terminal region of the envelope V3 loop. Proc Natl Acad Sci U S A 1994; 91:11378-11382.
-
(1994)
Proc Natl Acad Sci U S A
, vol.91
, pp. 11378-11382
-
-
Itescu, S.1
Simonelli, P.F.2
Winchester, R.J.3
Ginsberg, H.S.4
-
93
-
-
0026600926
-
Biological phenotype of human immunodeficiency virus type 1 clones at different stages of infection: progression of disease is associated with a shift from monocytotropic to T-celltropic virus population
-
Schuitemaker H, Koot M, Kootstra NA, et al. Biological phenotype of human immunodeficiency virus type 1 clones at different stages of infection: progression of disease is associated with a shift from monocytotropic to T-celltropic virus population. J Virol 1992; 66:1354-1360.
-
(1992)
J Virol
, vol.66
, pp. 1354-1360
-
-
Schuitemaker, H.1
Koot, M.2
Kootstra, N.A.3
-
94
-
-
0032789090
-
Patterns of chemokine receptor fusion cofactor utilization by human immunodeficiency virus type 1 variants from the lungs and blood
-
Singh A, Besson G, Mobasher A, Collman RG. Patterns of chemokine receptor fusion cofactor utilization by human immunodeficiency virus type 1 variants from the lungs and blood. J Virol 1999; 73:6680- 6690.
-
(1999)
J Virol
, vol.73
, pp. 6680-6690
-
-
Singh, A.1
Besson, G.2
Mobasher, A.3
Collman, R.G.4
-
95
-
-
0029411561
-
Low copy number and limited variability of proviral DNA in alveolar macrophages from HIV-1-infected patients: Evidence for genetic differences in HIV-1 between lung and blood macrophage populations
-
Nakata K, Weiden M, Harkin T, et al. Low copy number and limited variability of proviral DNA in alveolar macrophages from HIV-1-infected patients: Evidence for genetic differences in HIV-1 between lung and blood macrophage populations. Mol Med 1995; 1:744-757.
-
(1995)
Mol Med
, vol.1
, pp. 744-757
-
-
Nakata, K.1
Weiden, M.2
Harkin, T.3
-
96
-
-
70349204366
-
Evidence for limited genetic compartmentalization of HIV-1 between lung and blood
-
Heath L, Fox A, McClure J, et al. Evidence for limited genetic compartmentalization of HIV-1 between lung and blood. PLoS One 2009; 4:e6949.
-
(2009)
Plos One
, vol.4
-
-
Heath, L.1
Fox, A.2
McClure, J.3
|