메뉴 건너뛰기




Volumn 54, Issue 4, 2000, Pages 927-936

Cerebrospinal fluid HIV RNA originates from both local CNS and systemic sources

Author keywords

AIDS; CSF; HIV; Viral dynamics

Indexed keywords

VIRUS RNA;

EID: 0034701034     PISSN: 00283878     EISSN: None     Source Type: Journal    
DOI: 10.1212/WNL.54.4.927     Document Type: Article
Times cited : (175)

References (44)
  • 1
    • 0027195546 scopus 로고
    • Virologic markers of human immunodeficiency virus type 1 in cerebrospinal fluid. The HIV Neurobehavioral Research Center Group
    • Spector SA, Hsia K, Pratt D, et al. Virologic markers of human immunodeficiency virus type 1 in cerebrospinal fluid. The HIV Neurobehavioral Research Center Group. J Infect Dis 1993;168:68-74.
    • (1993) J Infect Dis , vol.168 , pp. 68-74
    • Spector, S.A.1    Hsia, K.2    Pratt, D.3
  • 2
    • 0032485436 scopus 로고    scopus 로고
    • Cerebrospinal fluid HIV-1 RNA levels: Correlation with HIV encephalitis
    • Cinque P, Vago L, Ceresa D, et al. Cerebrospinal fluid HIV-1 RNA levels: correlation with HIV encephalitis. AIDS 1998;12: 389-394.
    • (1998) AIDS , vol.12 , pp. 389-394
    • Cinque, P.1    Vago, L.2    Ceresa, D.3
  • 3
    • 0028825907 scopus 로고
    • Quantifying HIV-1 RNA using the polymerase chain reaction on cerebrospinal fluid and serum of seropositive individuals with and without neurologic abnormalities
    • Conrad AJ, Schmid P, Syndulko K, et al. Quantifying HIV-1 RNA using the polymerase chain reaction on cerebrospinal fluid and serum of seropositive individuals with and without neurologic abnormalities. J Acquir Immune Defic Syndr Hum Retrovirol 1995;10:425-435.
    • (1995) J Acquir Immune Defic Syndr Hum Retrovirol , vol.10 , pp. 425-435
    • Conrad, A.J.1    Schmid, P.2    Syndulko, K.3
  • 4
    • 15144358328 scopus 로고    scopus 로고
    • Cerebrospinal fluid human immunodeficiency virus type 1 RNA levels are elevated in neurocognitively impaired individuals with acquired immunodeficiency syndrome. HIV Neurobehavioral Research Center Group
    • Ellis RJ, Hsia K, Spector SA, et al. Cerebrospinal fluid human immunodeficiency virus type 1 RNA levels are elevated in neurocognitively impaired individuals with acquired immunodeficiency syndrome. HIV Neurobehavioral Research Center Group. Ann Neurol 1997;42:679-688.
    • (1997) Ann Neurol , vol.42 , pp. 679-688
    • Ellis, R.J.1    Hsia, K.2    Spector, S.A.3
  • 5
    • 0032122490 scopus 로고    scopus 로고
    • Cellular and anatomical reservoirs of HIV-1 in patients receiving potent antiretroviral combination therapy
    • Schrager LK, D'Souza MP. Cellular and anatomical reservoirs of HIV-1 in patients receiving potent antiretroviral combination therapy. JAMA 1998;280:67-71.
    • (1998) JAMA , vol.280 , pp. 67-71
    • Schrager, L.K.1    D'Souza, M.P.2
  • 6
    • 0032578396 scopus 로고    scopus 로고
    • Drug concentration heterogeneity facilitates the evolution of drug resistance
    • Kepler TB, Perelson AS. Drug concentration heterogeneity facilitates the evolution of drug resistance. Proc Natl Acad Sci USA 1998;95:11514-11519.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 11514-11519
    • Kepler, T.B.1    Perelson, A.S.2
  • 7
    • 0030727486 scopus 로고    scopus 로고
    • Relationship between human immunodeficiency virus-associated dementia and viral load in cerebrospinal fluid and brain
    • McArthur JC, McClernon DR, Cronin MF, et al. Relationship between human immunodeficiency virus-associated dementia and viral load in cerebrospinal fluid and brain. Ann Neurol 1997;42:689-698.
    • (1997) Ann Neurol , vol.42 , pp. 689-698
    • McArthur, J.C.1    McClernon, D.R.2    Cronin, M.F.3
  • 8
    • 0029807761 scopus 로고    scopus 로고
    • Evaluation of human immunodeficiency virus (HIV) type 1 RNA levels in cerebrospinal fluid and viral resistance to zidovudine in children with HIV encephalopathy
    • Sei S, Stewart SK, Farley M, et al. Evaluation of human immunodeficiency virus (HIV) type 1 RNA levels in cerebrospinal fluid and viral resistance to zidovudine in children with HIV encephalopathy. J Infect Dis 1996;174:1200-1206.
    • (1996) J Infect Dis , vol.174 , pp. 1200-1206
    • Sei, S.1    Stewart, S.K.2    Farley, M.3
  • 9
    • 0030901509 scopus 로고    scopus 로고
    • Levels of human immunodeficiency virus type 1 RNA in cerebrospinal fluid correlate with AIDS dementia stage
    • Brew BJ, Pemberton L, Cunningham P, Law MG. Levels of human immunodeficiency virus type 1 RNA in cerebrospinal fluid correlate with AIDS dementia stage. J Infect Dis 1997; 175:963-966.
    • (1997) J Infect Dis , vol.175 , pp. 963-966
    • Brew, B.J.1    Pemberton, L.2    Cunningham, P.3    Law, M.G.4
  • 10
    • 0029833018 scopus 로고    scopus 로고
    • AIDS dementia is associated with massive, activated HIV-1 infection and concomitant expression of several cytokines
    • Nuovo GJ, Alfieri ML. AIDS dementia is associated with massive, activated HIV-1 infection and concomitant expression of several cytokines. Mol Med 1996;2:358-366.
    • (1996) Mol Med , vol.2 , pp. 358-366
    • Nuovo, G.J.1    Alfieri, M.L.2
  • 11
    • 0028024080 scopus 로고
    • Human immunodeficiency virus encephalitis is the pathological correlate of dementia in acquired immunodeficiency syndrome
    • Wiley CA, Achim C. Human immunodeficiency virus encephalitis is the pathological correlate of dementia in acquired immunodeficiency syndrome. Ann Neurol 1994;36:673-676.
    • (1994) Ann Neurol , vol.36 , pp. 673-676
    • Wiley, C.A.1    Achim, C.2
  • 14
    • 0031908242 scopus 로고    scopus 로고
    • High human immunodeficiency virus type 1 RNA load in the cerebrospinal fluid from patients with lymphocytic meningitis
    • Morris L, Silber E, Sonnenberg P, et al. High human immunodeficiency virus type 1 RNA load in the cerebrospinal fluid from patients with lymphocytic meningitis. J Infect Dis 1998; 177:473-476.
    • (1998) J Infect Dis , vol.177 , pp. 473-476
    • Morris, L.1    Silber, E.2    Sonnenberg, P.3
  • 17
    • 0023636898 scopus 로고
    • Human immunodeficiency virus-associated meningitis. Clinical course and correlations
    • Hollander H, Stringari S. Human immunodeficiency virus-associated meningitis. Clinical course and correlations. Am J Med 1987;83:813-816.
    • (1987) Am J Med , vol.83 , pp. 813-816
    • Hollander, H.1    Stringari, S.2
  • 18
    • 0023791509 scopus 로고
    • Cerebrospinal fluid normalities and abnormalities in individuals infected with human immunodeficiency virus
    • Hollander H. Cerebrospinal fluid normalities and abnormalities in individuals infected with human immunodeficiency virus. J Infect Dis 1988;158:855-858.
    • (1988) J Infect Dis , vol.158 , pp. 855-858
    • Hollander, H.1
  • 19
    • 0028793468 scopus 로고
    • Lymphocyte phenotype and subset distribution in normal cerebrospinal fluid
    • Svenningsson A, Andersen O, Edsbagge M, Stemme S. Lymphocyte phenotype and subset distribution in normal cerebrospinal fluid. J Neuroimmunol 1995;63:39-46.
    • (1995) J Neuroimmunol , vol.63 , pp. 39-46
    • Svenningsson, A.1    Andersen, O.2    Edsbagge, M.3    Stemme, S.4
  • 20
    • 0024162362 scopus 로고
    • Flow cytometric quantitation of T cell phenotypes in cerebrospinal fluid and peripheral blood of homosexual men with and without antibodies to human immunodeficiency virus, type I
    • Margolick JB, McArthur JC, Scott ER, et al. Flow cytometric quantitation of T cell phenotypes in cerebrospinal fluid and peripheral blood of homosexual men with and without antibodies to human immunodeficiency virus, type I. J Neuroimmunol 1988;20:73-81.
    • (1988) J Neuroimmunol , vol.20 , pp. 73-81
    • Margolick, J.B.1    McArthur, J.C.2    Scott, E.R.3
  • 21
    • 0032476638 scopus 로고    scopus 로고
    • Cerebral spinal fluid lymphocytes are part of the normal recirculating lymphocyte pool
    • Seabrook TJ, Johnston M, Hay JB. Cerebral spinal fluid lymphocytes are part of the normal recirculating lymphocyte pool. J Neuroimmunol 1998;91:100-107.
    • (1998) J Neuroimmunol , vol.91 , pp. 100-107
    • Seabrook, T.J.1    Johnston, M.2    Hay, J.B.3
  • 22
    • 0032568245 scopus 로고    scopus 로고
    • Longitudinal comparison of HIV-1 RNA burden in plasma and cerebrospinal fluid in two patients starting triple combination antiretroviral therapy
    • Iftimovici E, Rabian C, Burgard M, Peytavin G, Rouzioux C, Viard JP. Longitudinal comparison of HIV-1 RNA burden in plasma and cerebrospinal fluid in two patients starting triple combination antiretroviral therapy. AIDS 1998;12:535-537.
    • (1998) AIDS , vol.12 , pp. 535-537
    • Iftimovici, E.1    Rabian, C.2    Burgard, M.3    Peytavin, G.4    Rouzioux, C.5    Viard, J.P.6
  • 23
    • 0030791962 scopus 로고    scopus 로고
    • Central nervous system as a sanctuary for HP7-1 infection despite treatment with zidovudine, lamivudine and indinavir
    • Pialoux G, Fournier S, Moulignier A, Poveda JD, Clavel F, Dupont B. Central nervous system as a sanctuary for HP7-1 infection despite treatment with zidovudine, lamivudine and indinavir. AIDS 1997;11:1302-1303.
    • (1997) AIDS , vol.11 , pp. 1302-1303
    • Pialoux, G.1    Fournier, S.2    Moulignier, A.3    Poveda, J.D.4    Clavel, F.5    Dupont, B.6
  • 24
    • 0029295139 scopus 로고
    • The HNRC 500 -neuropsychology of HIV infection at different disease stages. HIV Neurobehavioral Research Center
    • Heaton RK, Grant I, Butters N, et al. The HNRC 500 -neuropsychology of HIV infection at different disease stages. HIV Neurobehavioral Research Center. Journal of the International Neuropsychological Society 1995;1:231-251.
    • (1995) Journal of the International Neuropsychological Society , vol.1 , pp. 231-251
    • Heaton, R.K.1    Grant, I.2    Butters, N.3
  • 25
    • 0031002086 scopus 로고    scopus 로고
    • Neurocognitive impairment is an independent risk factor for death in HIV infection
    • Ellis RJ, Deutsch R, Heaton RK, et al. Neurocognitive impairment is an independent risk factor for death in HIV infection. Arch Neurol 1997;54:416-424.
    • (1997) Arch Neurol , vol.54 , pp. 416-424
    • Ellis, R.J.1    Deutsch, R.2    Heaton, R.K.3
  • 26
    • 0025822601 scopus 로고
    • Nomenclature and research case definitions for neurologic manifestations of human immunodeficiency virus-type 1 (HIV-1) infection. Report of a Working Group of the American Academy of Neurology AIDS Task Force
    • AAN. Nomenclature and research case definitions for neurologic manifestations of human immunodeficiency virus-type 1 (HIV-1) infection. Report of a Working Group of the American Academy of Neurology AIDS Task Force. Neurology 1991;41: 778-785.
    • (1991) Neurology , vol.41 , pp. 778-785
  • 28
    • 0029967721 scopus 로고    scopus 로고
    • HIV-1 dynamics in vivo: Virion clearance rate, infected cell life-span, and viral generation time
    • Perelson AS, Neumann AU, Markowitz M, Leonard JM, Ho DD. HIV-1 dynamics in vivo: virion clearance rate, infected cell life-span, and viral generation time. Science 1996;271: 1582-1586.
    • (1996) Science , vol.271 , pp. 1582-1586
    • Perelson, A.S.1    Neumann, A.U.2    Markowitz, M.3    Leonard, J.M.4    Ho, D.D.5
  • 29
    • 0028069547 scopus 로고
    • Rapid and simple PCR assay for quantitation of human immunodeficiency virus type 1 RNA in plasma: Application to acute retroviral infection
    • Mulder J, McKinney N, Christopherson C, Sninsky J, Greenfield L, Kwok S. Rapid and simple PCR assay for quantitation of human immunodeficiency virus type 1 RNA in plasma: application to acute retroviral infection. J Clin Microbiol 1994; 32:292-300.
    • (1994) J Clin Microbiol , vol.32 , pp. 292-300
    • Mulder, J.1    McKinney, N.2    Christopherson, C.3    Sninsky, J.4    Greenfield, L.5    Kwok, S.6
  • 30
    • 15144342918 scopus 로고    scopus 로고
    • Kinetics of response in lymphoid tissues to antiretroviral therapy of HPV-1 infection
    • Cavert W, Notermans DW, Staskus K, et al. Kinetics of response in lymphoid tissues to antiretroviral therapy of HPV-1 infection. Science 1997;276:960-964.
    • (1997) Science , vol.276 , pp. 960-964
    • Cavert, W.1    Notermans, D.W.2    Staskus, K.3
  • 31
    • 0028318761 scopus 로고
    • Cerebrospinal fluid production and dynamics in normal aging: A MRI phase-mapping study
    • Gideon P, Thomsen C, Ståhlberg F, Henriksen O. Cerebrospinal fluid production and dynamics in normal aging: a MRI phase-mapping study. Acta Neurol Scand 1994;89:362-366.
    • (1994) Acta Neurol Scand , vol.89 , pp. 362-366
    • Gideon, P.1    Thomsen, C.2    Ståhlberg, F.3    Henriksen, O.4
  • 32
    • 0030001660 scopus 로고    scopus 로고
    • Quantitation of human immunodeficiency virus in brains of demented and nondemented patients with acquired immunodeficiency syndrome
    • Johnson RT, Glass JD, McArthur JC, Chesebro BW. Quantitation of human immunodeficiency virus in brains of demented and nondemented patients with acquired immunodeficiency syndrome. Ann Neurol 1996;39:392-395.
    • (1996) Ann Neurol , vol.39 , pp. 392-395
    • Johnson, R.T.1    Glass, J.D.2    McArthur, J.C.3    Chesebro, B.W.4
  • 33
    • 0029100832 scopus 로고
    • Traffic of hematogenous cells through the central nervous system
    • Williams KC, Hickey WF. Traffic of hematogenous cells through the central nervous system. Curr Top Microbiol Immunol 1995;202:221-245.
    • (1995) Curr Top Microbiol Immunol , vol.202 , pp. 221-245
    • Williams, K.C.1    Hickey, W.F.2
  • 34
    • 0027732250 scopus 로고
    • Penetration of zidovudine into the cerebrospinal fluid of patients infected with HIV
    • Burger DM, Kraaijeveld CL, Meenhorst PL, et al. Penetration of zidovudine into the cerebrospinal fluid of patients infected with HIV. AIDS 1993;7:1581-1587.
    • (1993) AIDS , vol.7 , pp. 1581-1587
    • Burger, D.M.1    Kraaijeveld, C.L.2    Meenhorst, P.L.3
  • 37
    • 0031737417 scopus 로고    scopus 로고
    • Beta-chemokines MCP-1, RANTES are selectively increased in cerebrospinal fluid of patients with human immunodeficiency virus-associated dementia
    • Kelder W, McArthur JC, Nance-Sproson T, McClernon D, Griffin DE. Beta-chemokines MCP-1, RANTES are selectively increased in cerebrospinal fluid of patients with human immunodeficiency virus-associated dementia. Ann Neurol 1998; 44:831-835.
    • (1998) Ann Neurol , vol.44 , pp. 831-835
    • Kelder, W.1    McArthur, J.C.2    Nance-Sproson, T.3    McClernon, D.4    Griffin, D.E.5
  • 38
    • 0030692061 scopus 로고    scopus 로고
    • Chemotactic activity on mononuclear cells in the cerebrospinal fluid of patients with viral meningitis is mediated by interferon-gamma inducible protein-10 and monocyte chemotactic protein-1
    • Lahrtz F, Piali L, Nadal D, et al. Chemotactic activity on mononuclear cells in the cerebrospinal fluid of patients with viral meningitis is mediated by interferon-gamma inducible protein-10 and monocyte chemotactic protein-1. Eur J Immunol 1997;27:2484-2489.
    • (1997) Eur J Immunol , vol.27 , pp. 2484-2489
    • Lahrtz, F.1    Piali, L.2    Nadal, D.3
  • 40
    • 33751300511 scopus 로고    scopus 로고
    • Role of leukocytes in cerebral autoregulation and hyperemia in bacterial meningitis in rabbits
    • Slater AJ, Berkowitz ID, Wilson DA, Traystman RJ. Role of leukocytes in cerebral autoregulation and hyperemia in bacterial meningitis in rabbits. Am J Physiol 1997;273:380-386.
    • (1997) Am J Physiol , vol.273 , pp. 380-386
    • Slater, A.J.1    Berkowitz, I.D.2    Wilson, D.A.3    Traystman, R.J.4
  • 41
    • 0029716222 scopus 로고    scopus 로고
    • Leukocyte trafficking in free-flowing cerebrospinal fluid of normal rhesus macaques (Macaca mulatta)
    • Hou FY, Coe CL, Erickson C. Leukocyte trafficking in free-flowing cerebrospinal fluid of normal rhesus macaques (Macaca mulatta). J Med Primatol 1996;25:8-13.
    • (1996) J Med Primatol , vol.25 , pp. 8-13
    • Hou, F.Y.1    Coe, C.L.2    Erickson, C.3
  • 42
    • 0030247077 scopus 로고    scopus 로고
    • Fluoxetine treatment alters leukocyte trafficking in the intrathecal compartment of the young primate
    • Coe CL, Hou FY, Clarke AS. Fluoxetine treatment alters leukocyte trafficking in the intrathecal compartment of the young primate. Biol Psychiatry 1996;40:361-367.
    • (1996) Biol Psychiatry , vol.40 , pp. 361-367
    • Coe, C.L.1    Hou, F.Y.2    Clarke, A.S.3
  • 43
    • 0031656727 scopus 로고    scopus 로고
    • Ultrasensitive reverse transcription-PCR assay for quantitation of human immunodeficiency virus type 1 RNA in plasma
    • Sun R, Ku J, Jayakar H, et al. Ultrasensitive reverse transcription-PCR assay for quantitation of human immunodeficiency virus type 1 RNA in plasma. J Clin Microbiol 1998; 36:2964-2969.
    • (1998) J Clin Microbiol , vol.36 , pp. 2964-2969
    • Sun, R.1    Ku, J.2    Jayakar, H.3
  • 44
    • 0032814302 scopus 로고    scopus 로고
    • Time course of cerebrospinal fluid responses to antiretroviral therapy: Evidence for variable compartmentalization of infection
    • Staprans S, Marlowe N, Glidden D, et al. Time course of cerebrospinal fluid responses to antiretroviral therapy: evidence for variable compartmentalization of infection. AIDS 1999;13:1051-1061.
    • (1999) AIDS , vol.13 , pp. 1051-1061
    • Staprans, S.1    Marlowe, N.2    Glidden, D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.