-
1
-
-
12144287284
-
LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR-1
-
DOI 10.1038/sj.emboj.7600110
-
Lizcano JM, et al. (2004) LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR-1. EMBO J 23:833-843. (Pubitemid 38418750)
-
(2004)
EMBO Journal
, vol.23
, Issue.4
, pp. 833-843
-
-
Lizcano, J.M.1
Goransson, O.2
Toth, R.3
Deak, M.4
Morrice, N.A.5
Boudeau, J.6
Hawley, S.A.7
Udd, L.8
Makela, T.P.9
Hardie, D.G.10
Alessi, D.R.11
-
2
-
-
11244300732
-
LKB1, the multitasking tumour suppressor kinase
-
DOI 10.1136/jcp.2003.015255
-
Marignani PA (2005) LKB1, the multitasking tumour suppressor kinase. J Clin Pathol 58:15-19. (Pubitemid 40070489)
-
(2005)
Journal of Clinical Pathology
, vol.58
, Issue.1
, pp. 15-19
-
-
Marignani, P.A.1
-
3
-
-
0034090975
-
The C. elegans par-4 gene encodes a putative serine-threonine kinase required for establishing embryonic asymmetry
-
Watts JL, Morton DG, Bestman J, Kemphues KJ (2000) The C. elegans par-4 gene encodes a putative serine-threonine kinase required for establishing embryonic asymmetry. Development 127:1467-1475. (Pubitemid 30232597)
-
(2000)
Development
, vol.127
, Issue.7
, pp. 1467-1475
-
-
Watts, J.L.1
Morton, D.G.2
Bestman, J.3
Kemphuesf, K.J.4
-
4
-
-
0026773728
-
par-4, a gene required for cytoplasmic localization and determination of specific cell types in Caenorhabditis elegans embryogenesis
-
Morton DG, Roos JM, Kemphues KJ (1992) par-4, a gene required for cytoplasmic localization and determination of specific cell types in Caenorhabditis elegans embryogenesis. Genetics 130:771-790.
-
(1992)
Genetics
, vol.130
, pp. 771-790
-
-
Morton, D.G.1
Roos, J.M.2
Kemphues, K.J.3
-
5
-
-
0037461735
-
A role for Drosophila LKB1 in anterior-posterior axis formation and epithelial polarity
-
DOI 10.1038/nature01296
-
Martin SG, St Johnston D (2003) A role for Drosophila LKB1 in anterior-posterior axis formation and epithelial polarity. Nature 421:379-384. (Pubitemid 36157936)
-
(2003)
Nature
, vol.421
, Issue.6921
, pp. 379-384
-
-
Martin, S.G.1
St Johnston, D.2
-
6
-
-
0035903028
-
Vascular abnormalities and deregulation of VEGF in Lkb1-deficient mice
-
DOI 10.1126/science.1062074
-
Ylikorkala A, et al. (2001) Vascular abnormalities and deregulation of VEGF in Lkb1-deficient mice. Science 293:1323-1326. (Pubitemid 32777423)
-
(2001)
Science
, vol.293
, Issue.5533
, pp. 1323-1326
-
-
Ylikorkala, A.1
Rossi, D.J.2
Korsisaari, N.3
Luukko, K.4
Alitalo, K.5
Henkemeyer, M.6
Makela, T.P.7
-
7
-
-
0037173013
-
Role of Lkb1, the causative gene of Peutz-Jegher's syndrome, in embryogenesis and polyposis
-
DOI 10.1073/pnas.122254599
-
Jishage K, et al. (2002) Role of Lkb1, the causative gene of Peutz-Jegher's syndrome, in embryogenesis and polyposis. Proc Natl Acad Sci USA 99:8903-8908. (Pubitemid 34693656)
-
(2002)
Proceedings of the National Academy of Sciences of the United States of America
, vol.99
, Issue.13
, pp. 8903-8908
-
-
Jishage, K.-I.1
Nezu, J.-I.2
Kawase, Y.3
Iwata, T.4
Watanabe, M.5
Miyoshi, A.6
Ose, A.7
Habu, K.8
Kake, T.9
Kamada, N.10
Ueda, O.11
Kinoshita, M.12
Jenne, D.E.13
Shimane, M.14
Suzuki, H.15
-
8
-
-
1542777034
-
Complete polarization of single intestinal epithelial cells upon activation of LKB1 by STRAD
-
DOI 10.1016/S0092-8674(04)00114-X, PII S009286740400114X
-
Baas AF, Kuipers J, van der Wel NN, Batlle E, Koerten HK, Peters PJ, Clevers HC (2004) Complete polarization of single intestinal epithelial cells upon activation of LKB1 by STRAD. Cell 116:457-466. (Pubitemid 38366321)
-
(2004)
Cell
, vol.116
, Issue.3
, pp. 457-466
-
-
Baas, A.F.1
Kuipers, J.2
Van Der Wel, N.N.3
Batlle, E.4
Koerten, H.K.5
Peters, P.J.6
Clevers, H.C.7
-
9
-
-
0029903396
-
Armadillo, bazooka, and stardust are critical for early stages in formation of the zonula adherens and maintenance of the polarized blastoderm epithelium in Drosophila
-
DOI 10.1083/jcb.134.1.149
-
Muller HA, Wieschaus E (1996) Armadillo, bazooka, and stardust are critical for early stages in formation of the zonula adherens and maintenance of the polarized blastoderm epithelium in Drosophila. J Cell Biol 134:149-163. (Pubitemid 26231527)
-
(1996)
Journal of Cell Biology
, vol.134
, Issue.1
, pp. 149-163
-
-
Muller, H.-A.J.1
Wieschaus, E.2
-
10
-
-
0035674837
-
Epithelial cell polarity and cell junctions in Drosophila
-
DOI 10.1146/annurev.genet.35.102401.091415
-
Tepass U, Tanentzapf G, Ward R, Fehon R (2001) Epithelial cell polarity and cell junctions in Drosophila. Annu Rev Genet 35:747-784. (Pubitemid 34032991)
-
(2001)
Annual Review of Genetics
, vol.35
, pp. 747-784
-
-
Tepass, U.1
Tanentzapf, G.2
-
11
-
-
0034617129
-
Cooperative regulation of cell polarity and growth by Drosophila tumor suppressors
-
DOI 10.1126/science.289.5476.113
-
Bilder D, Li M, Perrimon N (2000) Cooperative regulation of cell polarity and growth by Drosophila tumor suppressors. Science 289:113-116. (Pubitemid 30463303)
-
(2000)
Science
, vol.289
, Issue.5476
, pp. 113-116
-
-
Bilder, D.1
Li, M.2
Perrimon, N.3
-
12
-
-
34248185949
-
LKB1 and AMPK maintain epithelial cell polarity under energetic stress
-
DOI 10.1083/jcb.200702053
-
Mirouse V, Swick LL, Kazgan N, St Johnston D, Brenman JE (2007) LKB1 and AMPK maintain epithelial cell polarity under energetic stress. J Cell Biol 177:387-392. (Pubitemid 46718268)
-
(2007)
Journal of Cell Biology
, vol.177
, Issue.3
, pp. 387-392
-
-
Mirouse, V.1
Swick, L.L.2
Kazgan, N.3
St Johnston, D.4
Brenman, J.E.5
-
13
-
-
34250827107
-
Energy-dependent regulation of cell structure by AMP-activated protein kinase
-
DOI 10.1038/nature05828, PII NATURE05828
-
Lee JH, et al. (2007) Energy-dependent regulation of cell structure by AMP-activated protein kinase. Nature 447:1017-1020. (Pubitemid 46975745)
-
(2007)
Nature
, vol.447
, Issue.7147
, pp. 1017-1020
-
-
Lee, J.H.1
Koh, H.2
Kim, M.3
Kim, Y.4
Lee, S.Y.5
Karess, R.E.6
Lee, S.-H.7
Shong, M.8
Kim, J.-M.9
Kim, J.10
Chung, J.11
-
15
-
-
33751204464
-
AMP-activated protein kinase regulates the assembly of epithelial tight junctions
-
DOI 10.1073/pnas.0608531103
-
Zhang L, Li J, Young LH, Caplan MJ (2006) AMP-activated protein kinase regulates the assembly of epithelial tight junctions. Proc Natl Acad Sci USA 103:17272-17277. (Pubitemid 44788959)
-
(2006)
Proceedings of the National Academy of Sciences of the United States of America
, vol.103
, Issue.46
, pp. 17272-17277
-
-
Zhang, L.1
Li, J.2
Young, L.H.3
Caplan, M.J.4
-
16
-
-
33846448743
-
Activation of PAR-1 kinase and stimulation of tau phosphorylation by diverse signals require the tumor suppressor protein LKB1
-
DOI 10.1523/JNEUROSCI.5094-06.2007
-
Wang JW, Imai Y, Lu B (2007) Activation of PAR-1 kinase and stimulation of tau phosphorylation by diverse signals require the tumor suppressor protein LKB1. J Neurosci 27:574-581. (Pubitemid 46143761)
-
(2007)
Journal of Neuroscience
, vol.27
, Issue.3
, pp. 574-581
-
-
Wang, J.-W.1
Imai, Y.2
Lu, B.3
-
17
-
-
0028819903
-
Integrins and the development of three-dimensional structure in the Drosophila compound eye
-
Longley RL, Jr, and Ready DF (1995) Integrins and the development of three-dimensional structure in the Drosophila compound eye. Dev Biol 171:415-433.
-
(1995)
Dev Biol
, vol.171
, pp. 415-433
-
-
Longley Jr., R.L.1
Ready, D.F.2
-
18
-
-
33749397178
-
Neuroserpin binds Aβ and is a neuroprotective component of amyloid plaques in Alzheimer disease
-
DOI 10.1074/jbc.M600690200
-
Kinghorn KJ, et al. (2006) Neuroserpin binds Abeta and is a neuroprotective component of amyloid plaques in Alzheimer disease. J Biol Chem 281:29268-29277. (Pubitemid 44507070)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.39
, pp. 29268-29277
-
-
Kinghorn, K.J.1
Crowther, D.C.2
Sharp, L.K.3
Nerelius, C.4
Davis, R.L.5
Chang, H.T.6
Green, C.7
Gubb, D.C.8
Johansson, J.9
Lomas, D.A.10
-
19
-
-
0242300112
-
Distinct roles of Bazooka and Stardust in the specification of Drosophila photoreceptor membrane architecture
-
DOI 10.1073/pnas.2135347100
-
Hong Y, Ackerman L, Jan LY, Jan YN (2003) Distinct roles of Bazooka and Stardust in the specification of Drosophila photoreceptor membrane architecture. Proc Natl Acad Sci USA 100:12712-12717. (Pubitemid 37339964)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.22
, pp. 12712-12717
-
-
Hong, Y.1
Ackerman, L.2
Jan, L.Y.3
Jan, Y.-N.4
-
20
-
-
0037075580
-
Crumbs, the Drosophila homologue of human CRB1/RP12, is essential for photoreceptor morphogenesis
-
DOI 10.1038/nature721
-
Pellikka M, et al. (2002) Crumbs, the Drosophila homologue of human CRB1/RP12, is essential for photoreceptor morphogenesis. Nature 416:143-149. (Pubitemid 34246466)
-
(2002)
Nature
, vol.416
, Issue.6877
, pp. 143-149
-
-
Pellikka, M.1
Tanentzapf, G.2
Pinto, M.3
Smith, C.4
McGlade, C.J.5
Ready, D.F.6
Tepass, U.7
-
21
-
-
0035974861
-
Two-step process for photoreceptor formation in drosophila [1]
-
DOI 10.1038/35091076
-
Mollereau B, et al. (2001) Two-step process for photoreceptor formation in Drosophila. Nature 412:911-913. (Pubitemid 32821735)
-
(2001)
Nature
, vol.412
, Issue.6850
, pp. 911-913
-
-
Mollereau, B.1
Dominguez, M.2
Webel, R.3
Colley, N.J.4
Keung, B.5
De Celis, J.F.6
Desplan, C.7
-
22
-
-
0025916146
-
Interaction of bride of sevenless membrane-bound ligand and the sevenless tyrosine-kinase receptor
-
Kramer H, Cagan RL, Zipursky SL (1991) Interaction of bride of sevenless membrane-bound ligand and the sevenless tyrosine-kinase receptor. Nature 352:207-212. (Pubitemid 21912312)
-
(1991)
Nature
, vol.352
, Issue.6332
, pp. 207-212
-
-
Kramer, H.1
Cagan, R.L.2
Zipursky, S.L.3
-
23
-
-
0029838174
-
Ras1 signaling and transcriptional competence in the R7 cell of Drosophila
-
Kauffmann RC, Li S, Gallagher PA, Zhang J, Carthew RW (1996) Ras1 signaling and transcriptional competence in the R7 cell of Drosophila. Genes Dev 10:2167-2178. (Pubitemid 26303872)
-
(1996)
Genes and Development
, vol.10
, Issue.17
, pp. 2167-2178
-
-
Kauffmann, R.C.1
Li, S.2
Gallagher, P.A.3
Zhang, J.4
Carthew, R.W.5
-
24
-
-
0026650597
-
Subtype determination of Drosophila embryonic external sensory organs by redundant homeo box genes BarH1 and BarH2
-
Higashijima S, Michiue T, Emori Y, Saigo K (1992) Subtype determination of Drosophila embryonic external sensory organs by redundant homeo box genes BarH1 and BarH2. Genes Dev 6:1005-1018.
-
(1992)
Genes Dev
, vol.6
, pp. 1005-1018
-
-
Higashijima, S.1
Michiue, T.2
Emori, Y.3
Saigo, K.4
-
25
-
-
0025276935
-
The homeo domain protein rough is expressed in a subset of cells in the developing Drosophila eye where it can specify photoreceptor cell subtype
-
Kimmel BE, Heberlein U, Rubin GM (1990) The homeo domain protein rough is expressed in a subset of cells in the developing Drosophila eye where it can specify photoreceptor cell subtype. Genes Dev 4:712-727. (Pubitemid 20175516)
-
(1990)
Genes and Development
, vol.4
, Issue.5
, pp. 712-727
-
-
Kimmel, B.E.1
Heberlein, U.2
Rubin, G.M.3
-
26
-
-
19344363080
-
The apical determinants aPKC and dPatj regulate frizzled-dependent planar cell polarity in the Drosophila eye
-
DOI 10.1016/j.cell.2005.03.014, PII S0092867405002862
-
Djiane A, Yogev S, Mlodzik M (2005) The apical determinants aPKC and dPatj regulate Frizzled-dependent planar cell polarity in the Drosophila eye. Cell 121:621-631. (Pubitemid 40720014)
-
(2005)
Cell
, vol.121
, Issue.4
, pp. 621-631
-
-
Djiane, A.1
Yogev, S.2
Mlodzik, M.3
-
27
-
-
0141502071
-
Interaction of Par-6 and Crumbs complexes is essential for photoreceptor morphogenesis in Drosophila
-
DOI 10.1242/dev.00648
-
Nam SC, Choi KW (2003) Interaction of Par-6 and Crumbs complexes is essential for photoreceptor morphogenesis in Drosophila. Development 130:4363-4372. (Pubitemid 37185324)
-
(2003)
Development
, vol.130
, Issue.18
, pp. 4363-4372
-
-
Nam, S.-C.1
Choi, K.-W.2
-
28
-
-
33645472726
-
DPATJ plays a role in retinal morphogenesis and protects against light-dependent degeneration of photoreceptor cells in the Drosophila eye
-
Richard M, Grawe F, Knust E (2006) DPATJ plays a role in retinal morphogenesis and protects against light-dependent degeneration of photoreceptor cells in the Drosophila eye. Dev Dyn 235:895-907.
-
(2006)
Dev Dyn
, vol.235
, pp. 895-907
-
-
Richard, M.1
Grawe, F.2
Knust, E.3
-
29
-
-
0037075546
-
Drosophila Crumbs is a positional cue in photoreceptor adherens junctions and rhabdomeres
-
DOI 10.1038/nature720
-
Izaddoost S, Nam SC, Bhat MA, Bellen HJ, Choi KW (2002) Drosophila Crumbs is a positional cue in photoreceptor adherens junctions and rhabdomeres. Nature 416:178-183. (Pubitemid 34246475)
-
(2002)
Nature
, vol.416
, Issue.6877
, pp. 178-182
-
-
Izaddoost, S.1
Nam, S.-C.2
Bhat, M.A.3
Bellen, H.J.4
Choi, K.-W.5
-
30
-
-
0031865770
-
+-ATPase subunits
-
Sun B, Wang W, Salvaterra PM (1998) Functional analysis and tissue-specific expression of Drosophila Na+,K+-ATPase subunits. J Neurochem 71:142-151. (Pubitemid 28292544)
-
(1998)
Journal of Neurochemistry
, vol.71
, Issue.1
, pp. 142-151
-
-
Sun, B.1
Wang, W.2
Salvaterra, P.M.3
-
31
-
-
0024465457
-
+)-ATPase alpha-subunit in Drosophila melanogaster
-
Lebovitz RM, Takeyasu K, Fambrough DM (1989) Molecular characterization and expression of the (Na+ + K+)-ATPase alpha-subunit in Drosophila melanogaster. EMBO J 8:193-202. (Pubitemid 19273962)
-
(1989)
EMBO Journal
, vol.8
, Issue.1
, pp. 193-202
-
-
Lebovitz, R.M.1
Takeyasu, K.2
Fambrough, D.M.3
-
32
-
-
0029024475
-
par-1, a gene required for establishing polarity in C. elegans embryos, encodes a putative Ser/Thr kinase that is asymmetrically distributed
-
Guo S, Kemphues KJ (1995) par-1, a gene required for establishing polarity in C. elegans embryos, encodes a putative Ser/Thr kinase that is asymmetrically distributed. Cell 81:611-620.
-
(1995)
Cell
, vol.81
, pp. 611-620
-
-
Guo, S.1
Kemphues, K.J.2
-
33
-
-
0024284814
-
Identification of genes required for cytoplasmic localization in early C. elegans embryos
-
Kemphues KJ, Priess JR, Morton DG, Cheng NS (1988) Identification of genes required for cytoplasmic localization in early C. elegans embryos. Cell 52:311-320.
-
(1988)
Cell
, vol.52
, pp. 311-320
-
-
Kemphues, K.J.1
Priess, J.R.2
Morton, D.G.3
Cheng, N.S.4
-
34
-
-
34249890022
-
Antagonistic functions of Par-1 kinase and protein phosphatase 2A are required for localization of Bazooka and photoreceptor morphogenesis in Drosophila
-
DOI 10.1016/j.ydbio.2007.03.522, PII S0012160607002485
-
Nam SC, Mukhopadhyay B, Choi KW (2007) Antagonistic functions of Par-1 kinase and protein phosphatase 2A are required for localization of Bazooka and photoreceptor morphogenesis in Drosophila. Dev Biol 306:624-635. (Pubitemid 46873540)
-
(2007)
Developmental Biology
, vol.306
, Issue.2
, pp. 624-635
-
-
Nam, S.-C.1
Mukhopadhyay, B.2
Choi, K.-W.3
-
35
-
-
33645066885
-
Par-1 kinase establishes cell polarity and functions in Notch signaling in the Drosophila embryo
-
Bayraktar J, Zygmunt D, Carthew RW (2006) Par-1 kinase establishes cell polarity and functions in Notch signaling in the Drosophila embryo. J Cell Sci 119:711-721.
-
(2006)
J Cell Sci
, vol.119
, pp. 711-721
-
-
Bayraktar, J.1
Zygmunt, D.2
Carthew, R.W.3
-
36
-
-
28844433635
-
Medicine: The kinase LKB1 mediates glucose homeostasis in liver and therapeutic effects of metformin
-
DOI 10.1126/science.1120781
-
Shaw RJ, et al. (2005) The kinase LKB1 mediates glucose homeostasis in liver and therapeutic effects of metformin. Science 310:1642-1646. (Pubitemid 41780780)
-
(2005)
Science
, vol.310
, Issue.5754
, pp. 1642-1646
-
-
Shaw, R.J.1
Lamia, K.A.2
Vasquez, D.3
Koo, S.-H.4
Bardeesy, N.5
Depinho, R.A.6
Montminy, M.7
Cantley, L.C.8
-
37
-
-
34247511497
-
LKB1 and SAD Kinases Define a Pathway Required for the Polarization of Cortical Neurons
-
DOI 10.1016/j.cell.2007.03.025, PII S0092867407003911
-
Barnes AP, et al. (2007) LKB1 and SAD kinases define a pathway required for the polarization of cortical neurons. Cell 129:549-563. (Pubitemid 46660970)
-
(2007)
Cell
, vol.129
, Issue.3
, pp. 549-563
-
-
Barnes, A.P.1
Lilley, B.N.2
Pan, Y.A.3
Plummer, L.J.4
Powell, A.W.5
Raines, A.N.6
Sanes, J.R.7
Polleux, F.8
-
38
-
-
0034645049
-
Apical, lateral, and basal polarization cues contribute to the development of the follicular epithelium during Drosophila oogenesis
-
Tanentzapf G, Smith C, McGlade J, Tepass U (2000) Apical, lateral, and basal polarization cues contribute to the development of the follicular epithelium during Drosophila oogenesis. J Cell Biol 151:891-904.
-
(2000)
J Cell Biol
, vol.151
, pp. 891-904
-
-
Tanentzapf, G.1
Smith, C.2
McGlade, J.3
Tepass, U.4
-
39
-
-
0031214565
-
Epithelial differentiation in Drosophila
-
Tepass U (1997) Epithelial differentiation in Drosophila. BioEssays 19:673-682. (Pubitemid 27354087)
-
(1997)
BioEssays
, vol.19
, Issue.8
, pp. 673-682
-
-
Tepass, U.1
-
40
-
-
0024377179
-
The emergence of order in the Drosophila pupal retina
-
DOI 10.1016/0012-1606(89)90261-3
-
Cagan RL, Ready DF (1989) The emergence of order in the Drosophila pupal retina. Dev Biol 136:346-362. (Pubitemid 20006649)
-
(1989)
Developmental Biology
, vol.136
, Issue.2
, pp. 346-362
-
-
Cagan, R.L.1
Ready, D.F.2
|