메뉴 건너뛰기




Volumn 146, Issue 6, 2011, Pages 955-968

Regulation of the MEX-5 gradient by a spatially segregated kinase/phosphatase cycle

Author keywords

[No Author keywords available]

Indexed keywords

MEX 5 PROTEIN; PHOSPHATASE; PHOSPHATASE PP2A; PROTEINASE ACTIVATED RECEPTOR 1; RNA BINDING PROTEIN; UNCLASSIFIED DRUG;

EID: 80052951973     PISSN: 00928674     EISSN: 10974172     Source Type: Journal    
DOI: 10.1016/j.cell.2011.08.012     Document Type: Article
Times cited : (118)

References (65)
  • 2
    • 10344236460 scopus 로고    scopus 로고
    • PAR-2 is asymmetrically distributed and promotes association of P granules and PAR-1 with the cortex in C. elegans embryos
    • L. Boyd, S. Guo, D. Levitan, D.T. Stinchcomb, and K.J. Kemphues PAR-2 is asymmetrically distributed and promotes association of P granules and PAR-1 with the cortex in C. elegans embryos Development 122 1996 3075 3084 (Pubitemid 26371973)
    • (1996) Development , vol.122 , Issue.10 , pp. 3075-3084
    • Boyd, L.1    Quo, S.2    Levitan, D.3    Stinchcomb, D.T.4    Kemphues, K.J.5
  • 3
    • 0032864252 scopus 로고    scopus 로고
    • Spatial gradients of cellular phospho-proteins
    • DOI 10.1016/S0014-5793(99)01058-3, PII S0014579399010583
    • G.C. Brown, and B.N. Kholodenko Spatial gradients of cellular phospho-proteins FEBS Lett. 457 1999 452 454 (Pubitemid 29414741)
    • (1999) FEBS Letters , vol.457 , Issue.3 , pp. 452-454
    • Brown, G.C.1    Kholodenko, B.N.2
  • 4
    • 43049145823 scopus 로고    scopus 로고
    • PLK-1 asymmetry contributes to asynchronous cell division of C. elegans embryos
    • DOI 10.1242/dev.019075
    • Y. Budirahardja, and P. Gönczy PLK-1 asymmetry contributes to asynchronous cell division of C. elegans embryos Development 135 2008 1303 1313 (Pubitemid 351622474)
    • (2008) Development , vol.135 , Issue.7 , pp. 1303-1313
    • Budirahardja, Y.1    Gonczy, P.2
  • 5
    • 3042598129 scopus 로고    scopus 로고
    • C. elegans PAR proteins function by mobilizing and stabilizing asymmetrically localized protein complexes
    • DOI 10.1016/j.cub.2004.05.022, PII S0960982204003422
    • R.J. Cheeks, J.C. Canman, W.N. Gabriel, N. Meyer, S. Strome, and B. Goldstein C. elegans PAR proteins function by mobilizing and stabilizing asymmetrically localized protein complexes Curr. Biol. 14 2004 851 862 (Pubitemid 38800906)
    • (2004) Current Biology , vol.14 , Issue.10 , pp. 851-862
    • Cheeks, R.J.1    Canman, J.C.2    Gabriel, W.N.3    Meyer, N.4    Strome, S.5    Goldstein, B.6
  • 6
    • 32044471522 scopus 로고    scopus 로고
    • Bruno acts as a dual repressor of oskar translation, promoting mRNA oligomerization and formation of silencing particles
    • DOI 10.1016/j.cell.2006.01.031, PII S0092867406001292
    • M. Chekulaeva, M.W. Hentze, and A. Ephrussi Bruno acts as a dual repressor of oskar translation, promoting mRNA oligomerization and formation of silencing particles Cell 124 2006 521 533 (Pubitemid 43199438)
    • (2006) Cell , vol.124 , Issue.3 , pp. 521-533
    • Chekulaeva, M.1    Hentze, M.W.2    Ephrussi, A.3
  • 8
    • 0037386142 scopus 로고    scopus 로고
    • Polarization of the C. elegans zygote proceeds via distinct establishment and maintenance phases
    • DOI 10.1242/dev.00284
    • A.A. Cuenca, A. Schetter, D. Aceto, K. Kemphues, and G. Seydoux Polarization of the C. elegans zygote proceeds via distinct establishment and maintenance phases Development 130 2003 1255 1265 (Pubitemid 36410775)
    • (2003) Development , vol.130 , Issue.7 , pp. 1255-1265
    • Cuenca, A.A.1    Schetter, A.2    Aceto, D.3    Kemphues, K.4    Seydoux, G.5
  • 9
    • 77955736803 scopus 로고    scopus 로고
    • MEX-5 enrichment in the C. elegans early embryo mediated by differential diffusion
    • B.R. Daniels, T.M. Dobrowsky, E.M. Perkins, S.X. Sun, and D. Wirtz MEX-5 enrichment in the C. elegans early embryo mediated by differential diffusion Development 137 2010 2579 2585
    • (2010) Development , vol.137 , pp. 2579-2585
    • Daniels, B.R.1    Dobrowsky, T.M.2    Perkins, E.M.3    Sun, S.X.4    Wirtz, D.5
  • 10
    • 0842303319 scopus 로고    scopus 로고
    • Seeing Is Believing: The Bicoid Morphogen Gradient Matures
    • DOI 10.1016/S0092-8674(04)00037-6
    • A. Ephrussi, and D. St Johnston Seeing is believing: the bicoid morphogen gradient matures Cell 116 2004 143 152 (Pubitemid 38167308)
    • (2004) Cell , vol.116 , Issue.2 , pp. 143-152
    • Ephrussi, A.1    St. Johnston, D.2
  • 12
    • 53649103818 scopus 로고    scopus 로고
    • Processing bodies and germ granules are distinct RNA granules that interact in C. elegans embryos
    • C.M. Gallo, E. Munro, D. Rasoloson, C. Merritt, and G. Seydoux Processing bodies and germ granules are distinct RNA granules that interact in C. elegans embryos Dev. Biol. 323 2008 76 87
    • (2008) Dev. Biol. , vol.323 , pp. 76-87
    • Gallo, C.M.1    Munro, E.2    Rasoloson, D.3    Merritt, C.4    Seydoux, G.5
  • 14
    • 35549001736 scopus 로고    scopus 로고
    • The PAR Proteins: Fundamental Players in Animal Cell Polarization
    • DOI 10.1016/j.devcel.2007.10.007, PII S1534580707003851
    • B. Goldstein, and I.G. Macara The PAR proteins: fundamental players in animal cell polarization Dev. Cell 13 2007 609 622 (Pubitemid 350011991)
    • (2007) Developmental Cell , vol.13 , Issue.5 , pp. 609-622
    • Goldstein, B.1    Macara, I.G.2
  • 15
    • 0029024475 scopus 로고
    • Par-1, a gene required for establishing polarity in C. elegans embryos, encodes a putative Ser/Thr kinase that is asymmetrically distributed
    • S. Guo, and K.J. Kemphues par-1, a gene required for establishing polarity in C. elegans embryos, encodes a putative Ser/Thr kinase that is asymmetrically distributed Cell 81 1995 611 620
    • (1995) Cell , vol.81 , pp. 611-620
    • Guo, S.1    Kemphues, K.J.2
  • 18
    • 0037230118 scopus 로고    scopus 로고
    • PAR-1 is required for morphogenesis of the Caenorhabditis elegans vulva
    • DOI 10.1006/dbio.2002.0866
    • D.D. Hurd, and K.J. Kemphues PAR-1 is required for morphogenesis of the Caenorhabditis elegans vulva Dev. Biol. 253 2003 54 65 (Pubitemid 36068003)
    • (2003) Developmental Biology , vol.253 , Issue.1 , pp. 54-65
    • Hurd, D.D.1    Kemphues, K.J.2
  • 19
    • 1942540791 scopus 로고    scopus 로고
    • Atypical PKC phosphorylates PAR-1 kinases to regulate localization and activity
    • DOI 10.1016/j.cub.2004.04.007, PII S0960982204002581
    • J.B. Hurov, J.L. Watkins, and H. Piwnica-Worms Atypical PKC phosphorylates PAR-1 kinases to regulate localization and activity Curr. Biol. 14 2004 736 741 (Pubitemid 38503613)
    • (2004) Current Biology , vol.14 , Issue.8 , pp. 736-741
    • Hurov, J.B.1    Watkins, J.L.2    Piwnica-Worms, H.3
  • 20
    • 0037192461 scopus 로고    scopus 로고
    • Visualization of a Ran-GTP gradient in interphase and mitotic Xenopus egg extracts
    • DOI 10.1126/science.1068798
    • P. Kalab, K. Weis, and R. Heald Visualization of a Ran-GTP gradient in interphase and mitotic Xenopus egg extracts Science 295 2002 2452 2456 (Pubitemid 34270259)
    • (2002) Science , vol.295 , Issue.5564 , pp. 2452-2456
    • Kalab, P.1    Weis, K.2    Heald, R.3
  • 21
    • 1342327361 scopus 로고    scopus 로고
    • C. elegans SUR-6/PR55 cooperates with LET-92/protein phosphatase 2A and promotes Raf activity independently of inhibitory Akt phosphorylation sites
    • DOI 10.1242/dev.00987
    • G. Kao, S. Tuck, D. Baillie, and M.V. Sundaram C. elegans SUR-6/PR55 cooperates with LET-92/protein phosphatase 2A and promotes Raf activity independently of inhibitory Akt phosphorylation sites Development 131 2004 755 765 (Pubitemid 38263191)
    • (2004) Development , vol.131 , Issue.4 , pp. 755-765
    • Kao, G.1    Tuck, S.2    Baillie, D.3    Sundaram, M.V.4
  • 22
    • 0034640089 scopus 로고    scopus 로고
    • PARsing embryonic polarity
    • K. Kemphues PARsing embryonic polarity Cell 101 2000 345 348
    • (2000) Cell , vol.101 , pp. 345-348
    • Kemphues, K.1
  • 23
    • 66949112940 scopus 로고    scopus 로고
    • PP2A antagonizes phosphorylation of Bazooka by PAR-1 to control apical-basal polarity in dividing embryonic neuroblasts
    • M.P. Krahn, D. Egger-Adam, and A. Wodarz PP2A antagonizes phosphorylation of Bazooka by PAR-1 to control apical-basal polarity in dividing embryonic neuroblasts Dev. Cell 16 2009 901 908
    • (2009) Dev. Cell , vol.16 , pp. 901-908
    • Krahn, M.P.1    Egger-Adam, D.2    Wodarz, A.3
  • 24
    • 0037088665 scopus 로고    scopus 로고
    • Interactions of CCCH zinc finger proteins with mRNA. Non-binding tristetraprolin mutants exert an inhibitory effect on degradation of AU-rich element-containing mRNAs
    • DOI 10.1074/jbc.M110395200
    • W.S. Lai, E.A. Kennington, and P.J. Blackshear Interactions of CCCH zinc finger proteins with mRNA: non-binding tristetraprolin mutants exert an inhibitory effect on degradation of AU-rich element-containing mRNAs J. Biol. Chem. 277 2002 9606 9613 (Pubitemid 34953050)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.11 , pp. 9606-9613
    • Lai, W.S.1    Kennington, E.A.2    Blackshear, P.J.3
  • 25
    • 70249114140 scopus 로고    scopus 로고
    • The polarity protein Par1b/EMK/MARK2 regulates T cell receptor-induced microtubule-organizing center polarization
    • J. Lin, K.K. Hou, H. Piwnica-Worms, and A.S. Shaw The polarity protein Par1b/EMK/MARK2 regulates T cell receptor-induced microtubule-organizing center polarization J. Immunol. 183 2009 1215 1221
    • (2009) J. Immunol. , vol.183 , pp. 1215-1221
    • Lin, J.1    Hou, K.K.2    Piwnica-Worms, H.3    Shaw, A.S.4
  • 26
    • 61349161193 scopus 로고    scopus 로고
    • Model for protein concentration gradients in the cytoplasm
    • K. Lipkow, and D.J. Odde Model for protein concentration gradients in the cytoplasm Cell. Mol. Bioeng. 1 2008 84 92
    • (2008) Cell. Mol. Bioeng. , vol.1 , pp. 84-92
    • Lipkow, K.1    Odde, D.J.2
  • 28
    • 79953674509 scopus 로고    scopus 로고
    • The formation of the Bicoid morphogen gradient requires protein movement from anteriorly localized mRNA
    • S.C. Little, G. Tkačik, T.B. Kneeland, E.F. Wieschaus, and T. Gregor The formation of the Bicoid morphogen gradient requires protein movement from anteriorly localized mRNA PLoS Biol. 9 2011 e1000596
    • (2011) PLoS Biol. , vol.9 , pp. 1000596
    • Little, S.C.1    Tkačik, G.2    Kneeland, T.B.3    Wieschaus, E.F.4    Gregor, T.5
  • 30
    • 35748968807 scopus 로고    scopus 로고
    • Spatial regulation of Fus3 MAP kinase activity through a reaction-diffusion mechanism in yeast pheromone signalling
    • DOI 10.1038/ncb1652, PII NCB1652
    • C.I. Maeder, M.A. Hink, A. Kinkhabwala, R. Mayr, P.I. Bastiaens, and M. Knop Spatial regulation of Fus3 MAP kinase activity through a reaction-diffusion mechanism in yeast pheromone signalling Nat. Cell Biol. 9 2007 1319 1326 (Pubitemid 350042364)
    • (2007) Nature Cell Biology , vol.9 , Issue.11 , pp. 1319-1326
    • Maeder, C.I.1    Hink, M.A.2    Kinkhabwala, A.3    Mayr, R.4    Bastiaens, P.I.H.5    Knop, M.6
  • 31
    • 77953510471 scopus 로고    scopus 로고
    • Structure and function of polarity-inducing kinase family MARK/Par-1 within the branch of AMPK/Snf1-related kinases
    • A. Marx, C. Nugoor, S. Panneerselvam, and E. Mandelkow Structure and function of polarity-inducing kinase family MARK/Par-1 within the branch of AMPK/Snf1-related kinases FASEB J. 24 2010 1637 1648
    • (2010) FASEB J. , vol.24 , pp. 1637-1648
    • Marx, A.1    Nugoor, C.2    Panneerselvam, S.3    Mandelkow, E.4
  • 32
    • 0029815260 scopus 로고    scopus 로고
    • The PIE-1 protein and germline specification in C. elegans embryos
    • DOI 10.1038/382710a0
    • C.C. Mello, C. Schubert, B. Draper, W. Zhang, R. Lobel, and J.R. Priess The PIE-1 protein and germline specification in C. elegans embryos Nature 382 1996 710 712 (Pubitemid 26282175)
    • (1996) Nature , vol.382 , Issue.6593 , pp. 710-712
    • Mello, C.C.1    Schubert, C.2    Draper, B.3    Zhang, W.4    Lobel, R.5    Priess, J.R.6
  • 33
    • 78649915767 scopus 로고    scopus 로고
    • Kinase associated-1 domains drive MARK/PAR1 kinases to membrane targets by binding acidic phospholipids
    • K. Moravcevic, J.M. Mendrola, K.R. Schmitz, Y.H. Wang, D. Slochower, P.A. Janmey, and M.A. Lemmon Kinase associated-1 domains drive MARK/PAR1 kinases to membrane targets by binding acidic phospholipids Cell 143 2010 966 977
    • (2010) Cell , vol.143 , pp. 966-977
    • Moravcevic, K.1    Mendrola, J.M.2    Schmitz, K.R.3    Wang, Y.H.4    Slochower, D.5    Janmey, P.A.6    Lemmon, M.A.7
  • 34
    • 34249890022 scopus 로고    scopus 로고
    • Antagonistic functions of Par-1 kinase and protein phosphatase 2A are required for localization of Bazooka and photoreceptor morphogenesis in Drosophila
    • DOI 10.1016/j.ydbio.2007.03.522, PII S0012160607002485
    • S.C. Nam, B. Mukhopadhyay, and K.W. Choi Antagonistic functions of Par-1 kinase and protein phosphatase 2A are required for localization of Bazooka and photoreceptor morphogenesis in Drosophila Dev. Biol. 306 2007 624 635 (Pubitemid 46873540)
    • (2007) Developmental Biology , vol.306 , Issue.2 , pp. 624-635
    • Nam, S.-C.1    Mukhopadhyay, B.2    Choi, K.-W.3
  • 35
    • 34247856078 scopus 로고    scopus 로고
    • Molecular basis of RNA recognition by the embryonic polarity determinant MEX-5
    • DOI 10.1074/jbc.M700079200
    • J.M. Pagano, B.M. Farley, L.M. McCoig, and S.P. Ryder Molecular basis of RNA recognition by the embryonic polarity determinant MEX-5 J. Biol. Chem. 282 2007 8883 8894 (Pubitemid 47093472)
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.12 , pp. 8883-8894
    • Pagano, J.M.1    Farley, B.M.2    McCoig, L.M.3    Ryder, S.P.4
  • 36
    • 40849136110 scopus 로고    scopus 로고
    • PAR proteins direct asymmetry of the cell cycle regulators Polo-like kinase and Cdc25
    • DOI 10.1083/jcb.200710018
    • D.M. Rivers, S. Moreno, M. Abraham, and J. Ahringer PAR proteins direct asymmetry of the cell cycle regulators Polo-like kinase and Cdc25 J. Cell Biol. 180 2008 877 885 (Pubitemid 351398415)
    • (2008) Journal of Cell Biology , vol.180 , Issue.5 , pp. 877-885
    • Rivers, D.M.1    Moreno, S.2    Abraham, M.3    Ahringer, J.4
  • 38
    • 0033634970 scopus 로고    scopus 로고
    • MEX-5 and MEX-6 function to establish soma/germline asymmetry in early C. elegans embryos
    • C.M. Schubert, R. Lin, C.J. de Vries, R.H. Plasterk, and J.R. Priess MEX-5 and MEX-6 function to establish soma/germline asymmetry in early C. elegans embryos Mol. Cell 5 2000 671 682
    • (2000) Mol. Cell , vol.5 , pp. 671-682
    • Schubert, C.M.1    Lin, R.2    De Vries, C.J.3    Plasterk, R.H.4    Priess, J.R.5
  • 39
    • 0037437172 scopus 로고    scopus 로고
    • Myosin and the PAR proteins polarize microfilament-dependent forces that shape and position mitotic spindles in Caenorhabditis elegans
    • DOI 10.1083/jcb.200210171
    • A.F. Severson, and B. Bowerman Myosin and the PAR proteins polarize microfilament-dependent forces that shape and position mitotic spindles in Caenorhabditis elegans J. Cell Biol. 161 2003 21 26 (Pubitemid 36459075)
    • (2003) Journal of Cell Biology , vol.161 , Issue.1 , pp. 21-26
    • Severson, A.F.1    Bowerman, B.2
  • 41
    • 77953283628 scopus 로고    scopus 로고
    • Cell polarity in eggs and epithelia: Parallels and diversity
    • D. St Johnston, and J. Ahringer Cell polarity in eggs and epithelia: parallels and diversity Cell 141 2010 757 774
    • (2010) Cell , vol.141 , pp. 757-774
    • St Johnston, D.1    Ahringer, J.2
  • 42
    • 0032524019 scopus 로고    scopus 로고
    • Exit from mitosis in Drosophila syncytial embryos requires proteolysis and cychn degradation, and is associated with localized dephosphorylation
    • T.T. Su, F. Sprenger, P.J. DiGregorio, S.D. Campbell, and P.H. O'Farrell Exit from mitosis in Drosophila syncytial embryos requires proteolysis and cyclin degradation, and is associated with localized dephosphorylation Genes Dev. 12 1998 1495 1503 (Pubitemid 28243634)
    • (1998) Genes and Development , vol.12 , Issue.10 , pp. 1495-1503
    • Su, T.T.1    Sprenger, F.2    DiGregorio, P.J.3    Campbell, S.D.4    O'Farrell, P.H.5
  • 43
    • 59149101705 scopus 로고    scopus 로고
    • MEX-5 asymmetry in one-cell C. elegans embryos requires PAR-4- and PAR-1-dependent phosphorylation
    • J.R. Tenlen, J.N. Molk, N. London, B.D. Page, and J.R. Priess MEX-5 asymmetry in one-cell C. elegans embryos requires PAR-4- and PAR-1-dependent phosphorylation Development 135 2008 3665 3675
    • (2008) Development , vol.135 , pp. 3665-3675
    • Tenlen, J.R.1    Molk, J.N.2    London, N.3    Page, B.D.4    Priess, J.R.5
  • 46
    • 0842328578 scopus 로고    scopus 로고
    • Modulation of KSR activity in Caenorhabditis elegans by Zn ions, PAR-1 kinase and PP2A phosphatase
    • DOI 10.1038/sj.emboj.7600025
    • J.H. Yoder, H. Chong, K.L. Guan, and M. Han Modulation of KSR activity in Caenorhabditis elegans by Zn ions, PAR-1 kinase and PP2A phosphatase EMBO J. 23 2004 111 119 (Pubitemid 38165752)
    • (2004) EMBO Journal , vol.23 , Issue.1 , pp. 111-119
    • Yoder, J.H.1    Chong, H.2    Guan, K.-I.3    Han, M.4
  • 47
    • 3242886603 scopus 로고    scopus 로고
    • PAR-3 is required for epithelial cell polarity in the distal spermatheca of C. elegans
    • DOI 10.1242/dev.01146
    • Aono, S., Legouis, R., Hoose, W.A., and Kemphues, K.J. (2004). PAR-3 is required for epithelial cell polarity in the distal spermatheca of C. elegans. Development 131, 2865-2874. (Pubitemid 38997275)
    • (2004) Development , vol.131 , Issue.12 , pp. 2865-2874
    • Aono, S.1    Legouis, R.2    Hoose, W.A.3    Kemphues, K.J.4
  • 48
    • 0004232671 scopus 로고
    • Expanded Edition edn (Princeton, New Jersey: Princeton University Press)
    • Berg, H.C. (1993). Random Walks in Biology, Expanded Edition edn (Princeton, New Jersey: Princeton University Press).
    • (1993) Random Walks in Biology
    • Berg, H.C.1
  • 49
    • 4444241998 scopus 로고    scopus 로고
    • A conserved protein network controls assembly of the outer kinetochore and its ability to sustain tension
    • DOI 10.1101/gad.1234104
    • Cheeseman, I.M., Niessen, S., Anderson, S., Hyndman, F., Yates, J.R., 3rd, Oegema, K., and Desai, A. (2004). A conserved protein network controls assembly of the outer kinetochore and its ability to sustain tension. Genes Dev. 18, 2255-2268. (Pubitemid 39209574)
    • (2004) Genes and Development , vol.18 , Issue.18 , pp. 2255-2268
    • Cheeseman, I.M.1    Niessen, S.2    Anderson, S.3    Hyndman, F.4    Yates III, J.R.5    Oegema, K.6    Desai, A.7
  • 50
    • 77955736803 scopus 로고    scopus 로고
    • MEX-5 enrichment in the C. elegans early embryo mediated by differential diffusion
    • Daniels, B.R., Dobrowsky, T.M., Perkins, E.M., Sun, S.X., and Wirtz, D. (2010). MEX-5 enrichment in the C. elegans early embryo mediated by differential diffusion. Development 137, 2579-2585.
    • (2010) Development , vol.137 , pp. 2579-2585
    • Daniels, B.R.1    Dobrowsky, T.M.2    Perkins, E.M.3    Sun, S.X.4    Wirtz, D.5
  • 52
    • 78650308096 scopus 로고    scopus 로고
    • Cytoplasmic partitioning of P granule components is not required to specify the germline in C. elegans
    • Gallo, C.M., Wang, J.T., Motegi, F., and Seydoux, G. (2010). Cytoplasmic partitioning of P granule components is not required to specify the germline in C. elegans. Science 330, 1685-1689.
    • (2010) Science , vol.330 , pp. 1685-1689
    • Gallo, C.M.1    Wang, J.T.2    Motegi, F.3    Seydoux, G.4
  • 53
    • 0029024475 scopus 로고
    • Par-1, a gene required for establishing polarity in C. elegans embryos, encodes a putative Ser/Thr kinase that is asymmetrically distributed
    • Guo, S., and Kemphues, K.J. (1995). par-1, a gene required for establishing polarity in C. elegans embryos, encodes a putative Ser/Thr kinase that is asymmetrically distributed. Cell 81, 611-620.
    • (1995) Cell , vol.81 , pp. 611-620
    • Guo, S.1    Kemphues, K.J.2
  • 54
    • 0035462443 scopus 로고    scopus 로고
    • Zyg-8, a Gene Required for Spindle Positioning in C. elegans, Encodes a Doublecortin-Related Kinase that Promotes Microtubule Assembly
    • DOI 10.1016/S1534-5807(01)00046-6, PII S1534580701000466
    • Gönczy, P., Bellanger, J.M., Kirkham, M., Pozniakowski, A., Baumer, K., Phillips, J.B., and Hyman, A.A. (2001). zyg-8, a gene required for spindle positioning in C. elegans, encodes a doublecortin-related kinase that promotes microtubule assembly. Dev. Cell 1, 363-375. (Pubitemid 33586086)
    • (2001) Developmental Cell , vol.1 , Issue.3 , pp. 363-375
    • Gonczy, P.1    Bellanger, J.-M.2    Kirkham, M.3    Pozniakowski, A.4    Baumer, K.5    Phillips, J.B.6    Hyman, A.A.7
  • 55
    • 52949140596 scopus 로고    scopus 로고
    • C. elegans and H. sapiens mRNAs with edited 3′ UTRs are present on polysomes
    • Hundley, H.A., Krauchuk, A.A., and Bass, B.L. (2008). C. elegans and H. sapiens mRNAs with edited 3′ UTRs are present on polysomes. RNA 14, 2050-2060.
    • (2008) RNA , vol.14 , pp. 2050-2060
    • Hundley, H.A.1    Krauchuk, A.A.2    Bass, B.L.3
  • 56
    • 0037088665 scopus 로고    scopus 로고
    • Interactions of CCCH zinc finger proteins with mRNA. Non-binding tristetraprolin mutants exert an inhibitory effect on degradation of AU-rich element-containing mRNAs
    • DOI 10.1074/jbc.M110395200
    • Lai, W.S., Kennington, E.A., and Blackshear, P.J. (2002). Interactions of CCCH zinc finger proteins with mRNA: non-binding tristetraprolin mutants exert an inhibitory effect on degradation of AU-rich element-containing mRNAs. J. Biol. Chem. 277, 9606-9613. (Pubitemid 34953050)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.11 , pp. 9606-9613
    • Lai, W.S.1    Kennington, E.A.2    Blackshear, P.J.3
  • 57
    • 53249143880 scopus 로고    scopus 로고
    • 3′ UTRs are the primary regulators of gene expression in the C. elegans germline
    • Merritt, C., Rasoloson, D., Ko, D., and Seydoux, G. (2008). 3′ UTRs are the primary regulators of gene expression in the C. elegans germline. Curr. Biol. 18, 1476-1482.
    • (2008) Curr. Biol. , vol.18 , pp. 1476-1482
    • Merritt, C.1    Rasoloson, D.2    Ko, D.3    Seydoux, G.4
  • 58
    • 33750619877 scopus 로고    scopus 로고
    • Potential for Control of Signaling Pathways via Cell Size and Shape
    • DOI 10.1016/j.cub.2006.07.056, PII S0960982206019610
    • Meyers, J., Craig, J., and Odde, D.J. (2006). Potential for control of signaling pathways via cell size and shape. Curr. Biol. 16, 1685-1693. (Pubitemid 44691787)
    • (2006) Current Biology , vol.16 , Issue.17 , pp. 1685-1693
    • Meyers, J.1    Craig, J.2    Odde, DavidJ.3
  • 59
    • 0035099902 scopus 로고    scopus 로고
    • Creation of low-copy integrated transgenic lines in Caenorhabditis elegans
    • Praitis, V., Casey, E., Collar, D., and Austin, J. (2001). Creation of low-copy integrated transgenic lines in Caenorhabditis elegans. Genetics 157, 1217-1226. (Pubitemid 32225014)
    • (2001) Genetics , vol.157 , Issue.3 , pp. 1217-1226
    • Praitis, V.1    Casey, E.2    Collar, D.3    Austin, J.4
  • 60
    • 77957930053 scopus 로고    scopus 로고
    • Membrane invaginations reveal cortical sites that pull on mitotic spindles in one-cell C. elegans embryos
    • Redemann, S., Pecreaux, J., Goehring, N.W., Khairy, K., Stelzer, E.H., Hyman, A.A., and Howard, J. (2010). Membrane invaginations reveal cortical sites that pull on mitotic spindles in one-cell C. elegans embryos. PLoS ONE 5, e12301.
    • (2010) PLoS ONE , vol.5
    • Redemann, S.1    Pecreaux, J.2    Goehring, N.W.3    Khairy, K.4    Stelzer, E.H.5    Hyman, A.A.6    Howard, J.7
  • 61
    • 0033634970 scopus 로고    scopus 로고
    • MEX-5 and MEX-6 function to establish soma/germline asymmetry in early C. elegans embryos
    • Schubert, C.M., Lin, R., de Vries, C.J., Plasterk, R.H., and Priess, J.R. (2000). MEX-5 and MEX-6 function to establish soma/germline asymmetry in early C. elegans embryos. Mol. Cell 5, 671-682.
    • (2000) Mol. Cell , vol.5 , pp. 671-682
    • Schubert, C.M.1    Lin, R.2    De Vries, C.J.3    Plasterk, R.H.4    Priess, J.R.5
  • 62
    • 0037437172 scopus 로고    scopus 로고
    • Myosin and the PAR proteins polarize microfilament-dependent forces that shape and position mitotic spindles in Caenorhabditis elegans
    • DOI 10.1083/jcb.200210171
    • Severson, A.F., and Bowerman, B. (2003). Myosin and the PAR proteins polarize microfilament-dependent forces that shape and position mitotic spindles in Caenorhabditis elegans. J. Cell Biol. 161, 21-26. (Pubitemid 36459075)
    • (2003) Journal of Cell Biology , vol.161 , Issue.1 , pp. 21-26
    • Severson, A.F.1    Bowerman, B.2
  • 63
    • 30044443400 scopus 로고    scopus 로고
    • The C. elegans DYRK kinase MBK-2 marks oocyte proteins for degradation in response to meiotic maturation
    • DOI 10.1016/j.cub.2005.11.063, PII S0960982205014739
    • Stitzel, M.L., Pellettieri, J., and Seydoux, G. (2006). The C. elegans DYRK kinase MBK-2 marks oocyte proteins for degradation in response to meiotic maturation. Curr. Biol. 16, 56-62. (Pubitemid 43049886)
    • (2006) Current Biology , vol.16 , Issue.1 , pp. 56-62
    • Stitzel, M.L.1    Pellettieri, J.2    Seydoux, G.3
  • 64
    • 59149101705 scopus 로고    scopus 로고
    • MEX-5 asymmetry in one-cell C. elegans embryos requires PAR-4- and PAR-1-dependent phosphorylation
    • Tenlen, J.R., Molk, J.N., London, N., Page, B.D., and Priess, J.R. (2008). MEX-5 asymmetry in one-cell C. elegans embryos requires PAR-4- and PAR-1-dependent phosphorylation. Development 135, 3665-3675.
    • (2008) Development , vol.135 , pp. 3665-3675
    • Tenlen, J.R.1    Molk, J.N.2    London, N.3    Page, B.D.4    Priess, J.R.5
  • 65
    • 0032578911 scopus 로고    scopus 로고
    • Specific interference by ingested dsRNA
    • Timmons, L., and Fire, A. (1998). Specific interference by ingested dsRNA. Nature 395, 854.
    • (1998) Nature , vol.395 , pp. 854
    • Timmons, L.1    Fire, A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.