Manipulation of very few receptor discriminator residues greatly enhances receptor specificity of non-visual arrestins

Journal of Biological Chemistry

Volumn 287, Issue 35, 2012, Pages 29495-29505

  Gimenez, Luis E ^a   Vishnivetskiy, Sergey A ^a   Baameur, Faiza ^a   Gurevich, Vsevolod V ^a  

^a VANDERBILT UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADRENERGIC RECEPTORS; ARRESTINS; HIGH SELECTIVITY; KEY RESIDUES; RECEPTOR BINDING; RESONANCE ENERGIES;

BIOCHEMISTRY; BIOLOGY;

DISCRIMINATORS;

ARRESTIN 1; ARRESTIN 2; ARRESTIN 3; BETA 2 ADRENERGIC RECEPTOR; DOPAMINE 1 RECEPTOR; DOPAMINE 2 RECEPTOR; MUSCARINIC M2 RECEPTOR; RETINA S ANTIGEN; RHODOPSIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BIOLUMINESCENCE RESONANCE ENERGY TRANSFER; CONTROLLED STUDY; ENZYME SPECIFICITY; GENE MUTATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; RABBIT; SEQUENCE HOMOLOGY; SIGNAL TRANSDUCTION;

AMINO ACID SUBSTITUTION; ANIMALS; ARRESTINS; CELL LINE; HUMANS; MUTATION, MISSENSE; PROTEIN BINDING; RABBITS; RECEPTORS, G-PROTEIN-COUPLED; RHODOPSIN; SIGNAL TRANSDUCTION;

EID: 84865527500     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.366674     Document Type: Article

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