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Volumn 60, Issue 3, 2012, Pages 580-588

Integrating genetics and genomics in primary aldosteronism

Author keywords

[No Author keywords available]

Indexed keywords

ALDOSTERONE; ALDOSTERONE SYNTHASE; BETA CATENIN; CHOLESTEROL MONOOXYGENASE (SIDE CHAIN CLEAVING); CYTOCHROME P450 17; NUCLEAR RECEPTOR DAX 1; POTASSIUM CHANNEL; PREGNENOLONE; PROGESTERONE; SEROTONIN 4 RECEPTOR; TRANSCRIPTION FACTOR GATA 4; TRANSCRIPTION FACTOR GATA 6;

EID: 84865456726     PISSN: 0194911X     EISSN: 15244563     Source Type: Journal    
DOI: 10.1161/HYPERTENSIONAHA.111.188250     Document Type: Article
Times cited : (25)

References (81)
  • 1
    • 84858003270 scopus 로고    scopus 로고
    • Prevalence of primary aldosteronism in patient's cohorts and in population-based studies: A review of the current literature
    • Hannemann A, Wallaschofski H. Prevalence of primary aldosteronism in patient's cohorts and in population-based studies: a review of the current literature. Horm Metab Res. 2012;44:157-162.
    • (2012) Horm Metab Res , vol.44 , pp. 157-162
    • Hannemann, A.1    Wallaschofski, H.2
  • 2
    • 11144355719 scopus 로고    scopus 로고
    • Trends in the prevalence of primary aldosteronism, aldosterone-producing adenomas, and surgically correctable aldosterone-dependent hypertension
    • Plouin PF, Amar L, Chatellier G. Trends in the prevalence of primary aldosteronism, aldosterone-producing adenomas, and surgically correctable aldosterone-dependent hypertension. Nephrol Dial Transplant. 2004;19:774-777.
    • (2004) Nephrol Dial Transplant , vol.19 , pp. 774-777
    • Plouin, P.F.1    Amar, L.2    Chatellier, G.3
  • 5
    • 17144421237 scopus 로고    scopus 로고
    • Evidence for an increased rate of cardiovascular events in patients with primary aldosteronism
    • Milliez P, Girerd X, Plouin PF, Blacher J, Safar ME, Mourad JJ. Evidence for an increased rate of cardiovascular events in patients with primary aldosteronism. J Am Coll Cardiol. 2005;45:1243-1248.
    • (2005) J Am Coll Cardiol , vol.45 , pp. 1243-1248
    • Milliez, P.1    Girerd, X.2    Plouin, P.F.3    Blacher, J.4    Safar, M.E.5    Mourad, J.J.6
  • 8
    • 58149250491 scopus 로고    scopus 로고
    • Blood pressure outcome of adrenalectomy in patients with primary hyperaldosteronism with or without unilateral adenoma
    • Letavernier E, Peyrard S, Amar L, Zinzindohoue F, Fiquet B, Plouin PF. Blood pressure outcome of adrenalectomy in patients with primary hyperaldosteronism with or without unilateral adenoma. J Hypertens. 2008;26: 1816-1823.
    • (2008) J Hypertens , vol.26 , pp. 1816-1823
    • Letavernier, E.1    Peyrard, S.2    Amar, L.3    Zinzindohoue, F.4    Fiquet, B.5    Plouin, P.F.6
  • 11
    • 72149099639 scopus 로고    scopus 로고
    • Mineralocorticoid receptors in the metabolic syndrome
    • Zennaro MC, Caprio M, Feve B. Mineralocorticoid receptors in the metabolic syndrome. Trends Endocrinol Metab. 2009;20:444-451.
    • (2009) Trends Endocrinol Metab , vol.20 , pp. 444-451
    • Zennaro, M.C.1    Caprio, M.2    Feve, B.3
  • 14
    • 0014029230 scopus 로고
    • Hypertension, increased aldosterone secretion and low plasma renin activity relieved by dexamethasone
    • Sutherland DJ, Ruse JL, Laidlaw JC. Hypertension, increased aldosterone secretion and low plasma renin activity relieved by dexamethasone. Can Med Assoc J. 1966;95:1109-1119.
    • (1966) Can Med Assoc J , vol.95 , pp. 1109-1119
    • Sutherland, D.J.1    Ruse, J.L.2    Laidlaw, J.C.3
  • 17
    • 0026580019 scopus 로고
    • A chimaeric 11β-hydroxylase aldosterone synthase gene causes glucocorticoid-remediable aldosteronism and human hypertension
    • Lifton RP, Dluhy RG, Powers M, Rich GM, Cook S, Ulick S, Lalouel JM. A chimaeric 11β-hydroxylase aldosterone synthase gene causes glucocorticoid-remediable aldosteronism and human hypertension. Nature. 1992;355:262-265.
    • (1992) Nature , vol.355 , pp. 262-265
    • Lifton, R.P.1    Dluhy, R.G.2    Powers, M.3    Rich, G.M.4    Cook, S.5    Ulick, S.6    Lalouel, J.M.7
  • 18
    • 0026701168 scopus 로고
    • Glucocorticoid-suppressible hyperaldosteronism results from hybrid genes created by unequal crossovers between CYP11B1 and CYP11B2
    • Pascoe L, Curnow KM, Slutsker L, Connell JM, Speiser PW, New MI, White PC. Glucocorticoid-suppressible hyperaldosteronism results from hybrid genes created by unequal crossovers between CYP11B1 and CYP11B2. Proc Natl Acad Sci USA. 1992;89:8327-8331.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 8327-8331
    • Pascoe, L.1    Curnow, K.M.2    Slutsker, L.3    Connell, J.M.4    Speiser, P.W.5    New, M.I.6    White, P.C.7
  • 20
    • 18944364034 scopus 로고    scopus 로고
    • Familial aspect of primary hyperaldosteronism: Analysis of families compatible with primary hyperaldosteronism type 2 [in French]
    • Medeau V, Assie G, Zennaro MC, Clauser E, Plouin PF, Jeunemaitre X. Familial aspect of primary hyperaldosteronism: analysis of families compatible with primary hyperaldosteronism type 2 [in French]. Ann Endocrinol (Paris). 2005;66:240-246.
    • (2005) Ann Endocrinol (Paris) , vol.66 , pp. 240-246
    • Medeau, V.1    Assie, G.2    Zennaro, M.C.3    Clauser, E.4    Plouin, P.F.5    Jeunemaitre, X.6
  • 28
    • 0042335982 scopus 로고    scopus 로고
    • Primary aldosteronism: From genesis to genetics
    • Stowasser M, Gordon RD. Primary aldosteronism: from genesis to genetics. Trends Endocrinol Metab. 2003;14:310-317.
    • (2003) Trends Endocrinol Metab , vol.14 , pp. 310-317
    • Stowasser, M.1    Gordon, R.D.2
  • 31
    • 0034911606 scopus 로고    scopus 로고
    • Vitro release of aldosterone and cortisol in human adrenal adenomas correlates to mRNA expression of steroidogenic enzymes for genes CYP11B2 and CYP17
    • Enberg U, Farnebo LO, Wedell A, Grondal S, Thoren M, Grimelius L, Kjellman M, Backdahl M, Hamberger B. In vitro release of aldosterone and cortisol in human adrenal adenomas correlates to mRNA expression of steroidogenic enzymes for genes CYP11B2 and CYP17. World J Surg. 2001;25:957-966.
    • (2001) World J Surg , vol.25 , pp. 957-966
    • Enberg, U.1    Farnebo, L.O.2    Wedell, A.3    Grondal, S.4    Thoren, M.5    Grimelius, L.6    Kjellman, M.7    Backdahl, M.8    Hamberger, B.9
  • 34
    • 4344634801 scopus 로고    scopus 로고
    • Postoperative differentiation between unilateral adrenal adenoma and bilateral adrenal hyperplasia in primary aldosteronism by mRNA expression of the gene CYP11B2
    • Enberg U, Volpe C, Hoog A, Wedell A, Farnebo LO, Thoren M, Hamberger B. Postoperative differentiation between unilateral adrenal adenoma and bilateral adrenal hyperplasia in primary aldosteronism by mRNA expression of the gene CYP11B2. Eur J Endocrinol. 2004;151: 73-85.
    • (2004) Eur J Endocrinol , vol.151 , pp. 73-85
    • Enberg, U.1    Volpe, C.2    Hoog, A.3    Wedell, A.4    Farnebo, L.O.5    Thoren, M.6    Hamberger, B.7
  • 39
    • 84860776956 scopus 로고    scopus 로고
    • Microarray, qPCR, and KCNJ5 sequencing of aldosterone-producing adenomas reveal differences in genotype and phenotype between zona glomerulosa-and zona fasciculata-like tumors
    • Azizan EA, Lam BY, Newhouse SJ, Zhou J, Kuc RE, Clarke J, Happerfield L, Marker A, Hoffman GJ, Brown MJ. Microarray, qPCR, and KCNJ5 sequencing of aldosterone-producing adenomas reveal differences in genotype and phenotype between zona glomerulosa-and zona fasciculata-like tumors. J Clin Endocrinol Metab. 2012;97:E819-E829.
    • (2012) J Clin Endocrinol Metab , vol.97
    • Azizan, E.A.1    Lam, B.Y.2    Newhouse, S.J.3    Zhou, J.4    Kuc, R.E.5    Clarke, J.6    Happerfield, L.7    Marker, A.8    Hoffman, G.J.9    Brown, M.J.10
  • 43
    • 18844464024 scopus 로고    scopus 로고
    • Control of aldosterone secretion: A model for convergence in cellular signaling pathways
    • Spat A, Hunyady L. Control of aldosterone secretion: a model for convergence in cellular signaling pathways. Physiol Rev. 2004;84:489-539.
    • (2004) Physiol Rev , vol.84 , pp. 489-539
    • Spat, A.1    Hunyady, L.2
  • 45
    • 0035118956 scopus 로고    scopus 로고
    • Ectopic and abnormal hormone receptors in adrenal Cushing's syndrome
    • Lacroix A, Ndiaye N, Tremblay J, Hamet P. Ectopic and abnormal hormone receptors in adrenal Cushing's syndrome. Endocr Rev. 2001; 22:75-110.
    • (2001) Endocr Rev , vol.22 , pp. 75-110
    • Lacroix, A.1    Ndiaye, N.2    Tremblay, J.3    Hamet, P.4
  • 47
    • 35848946407 scopus 로고    scopus 로고
    • G-proteincoupled receptors in aldosterone-producing adenomas: A potential cause of hyperaldosteronism
    • Ye P, Mariniello B, Mantero F, Shibata H, Rainey WE. G-proteincoupled receptors in aldosterone-producing adenomas: a potential cause of hyperaldosteronism. J Endocrinol. 2007;195:39-48.
    • (2007) J Endocrinol , vol.195 , pp. 39-48
    • Ye, P.1    Mariniello, B.2    Mantero, F.3    Shibata, H.4    Rainey, W.E.5
  • 48
    • 0035062143 scopus 로고    scopus 로고
    • ACTHreceptor expression, regulation and role in adrenocortial tumor formation
    • Beuschlein F, Fassnacht M, Klink A, Allolio B, Reincke M. ACTHreceptor expression, regulation and role in adrenocortial tumor formation. Eur J Endocrinol. 2001;144:199-206.
    • (2001) Eur J Endocrinol , vol.144 , pp. 199-206
    • Beuschlein, F.1    Fassnacht, M.2    Klink, A.3    Allolio, B.4    Reincke, M.5
  • 51
    • 0034751555 scopus 로고    scopus 로고
    • Production and metabolism of serotonin (5-HT) by the human adrenal cortex: Paracrine stimulation of aldosterone secretion by 5-HT
    • Lefebvre H, Compagnon P, Contesse V, Delarue C, Thuillez C, Vaudry H, Kuhn JM. Production and metabolism of serotonin (5-HT) by the human adrenal cortex: paracrine stimulation of aldosterone secretion by 5-HT. J Clin Endocrinol Metab. 2001;86:5001-5007.
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 5001-5007
    • Lefebvre, H.1    Compagnon, P.2    Contesse, V.3    Delarue, C.4    Thuillez, C.5    Vaudry, H.6    Kuhn, J.M.7
  • 52
    • 0027633578 scopus 로고
    • Angiotensin II receptor subtypes on adrenal adenoma in primary hyperaldosteronism
    • Cook MD, Phillips MI, Cook VI, Kimura B, Wilcox CS. Angiotensin II receptor subtypes on adrenal adenoma in primary hyperaldosteronism. J Am Soc Nephrol. 1993;4:111-116.
    • (1993) J Am Soc Nephrol , vol.4 , pp. 111-116
    • Cook, M.D.1    Phillips, M.I.2    Cook, V.I.3    Kimura, B.4    Wilcox, C.S.5
  • 54
    • 34249844952 scopus 로고    scopus 로고
    • Down-regulation of D2 dopamine receptor and increased protein kinase Cmu phosphorylation in aldosterone-producing adenoma play roles in aldosterone overproduction
    • Chang HW, Chu TS, Huang HY, Chueh SC, Wu VC, Chen YM, Hsieh BS, Wu KD. Down-regulation of D2 dopamine receptor and increased protein kinase Cmu phosphorylation in aldosterone-producing adenoma play roles in aldosterone overproduction. J Clin Endocrinol Metab. 2007; 92:1863-1870.
    • (2007) J Clin Endocrinol Metab , vol.92 , pp. 1863-1870
    • Chang, H.W.1    Chu, T.S.2    Huang, H.Y.3    Chueh, S.C.4    Wu, V.C.5    Chen, Y.M.6    Hsieh, B.S.7    Wu, K.D.8
  • 55
    • 0842334477 scopus 로고    scopus 로고
    • The orphan nuclear receptors NURR1 and NGFIB regulate adrenal aldosterone production
    • Bassett MH, Suzuki T, Sasano H, White PC, Rainey WE. The orphan nuclear receptors NURR1 and NGFIB regulate adrenal aldosterone production. Mol Endocrinol. 2004;18:279-290.
    • (2004) Mol Endocrinol , vol.18 , pp. 279-290
    • Bassett, M.H.1    Suzuki, T.2    Sasano, H.3    White, P.C.4    Rainey, W.E.5
  • 56
    • 77952948397 scopus 로고    scopus 로고
    • TASK1 and TASK3 potassium channels: Determinants of aldosterone secretion and adrenocortical zonation
    • Bandulik S, Penton D, Barhanin J, Warth R. TASK1 and TASK3 potassium channels: determinants of aldosterone secretion and adrenocortical zonation. Horm Metab Res. 2010;42:450-457.
    • (2010) Horm Metab Res , vol.42 , pp. 450-457
    • Bandulik, S.1    Penton, D.2    Barhanin, J.3    Warth, R.4
  • 62
    • 84863393293 scopus 로고    scopus 로고
    • Somatic mutations affecting the selectivity filter of KCNJ5 are frequent in 2 large unselected collections of adrenal aldosteronomas
    • Azizan EA, Murthy M, Stowasser M, Gordon R, Kowalski B, Xu S, Brown MJ, O'Shaughnessy KM. Somatic mutations affecting the selectivity filter of KCNJ5 are frequent in 2 large unselected collections of adrenal aldosteronomas. Hypertension. 2012;59:587-591.
    • (2012) Hypertension , vol.59 , pp. 587-591
    • Azizan, E.A.1    Murthy, M.2    Stowasser, M.3    Gordon, R.4    Kowalski, B.5    Xu, S.6    Brown, M.J.7    O'Shaughnessy, K.M.8
  • 64
    • 84859410866 scopus 로고    scopus 로고
    • Potassium channel mutant KCNJ5 T158A expression in HAC-15 cells increases aldosterone synthesis
    • Oki K, Plonczynski MW, Luis Lam M, Gomez-Sanchez EP, Gomez-Sanchez CE. Potassium channel mutant KCNJ5 T158A expression in HAC-15 cells increases aldosterone synthesis. Endocrinology. 2012;153: 1774-1782.
    • (2012) Endocrinology , vol.153 , pp. 1774-1782
    • Oki, K.1    Plonczynski, M.W.2    Luis Lam, M.3    Gomez-Sanchez, E.P.4    Gomez-Sanchez, C.E.5
  • 66
    • 77952956810 scopus 로고    scopus 로고
    • Teratocarcinoma-derived growth factor-1 is upregulated in aldosterone-producing adenomas and increases aldosterone secretion and inhibits apoptosis in vitro
    • Williams TA, Monticone S, Morello F, Liew CC, Mengozzi G, Pilon C, Asioli S, Sapino A, Veglio F, Mulatero P. Teratocarcinoma-derived growth factor-1 is upregulated in aldosterone-producing adenomas and increases aldosterone secretion and inhibits apoptosis in vitro. Hypertension. 2010;55:1468-1475.
    • (2010) Hypertension , vol.55 , pp. 1468-1475
    • Williams, T.A.1    Monticone, S.2    Morello, F.3    Liew, C.C.4    Mengozzi, G.5    Pilon, C.6    Asioli, S.7    Sapino, A.8    Veglio, F.9    Mulatero, P.10
  • 69
    • 84858705991 scopus 로고    scopus 로고
    • Visinin-like 1 is upregulated in aldosterone-producing adenomas with KCNJ5 mutations and protects from calcium-induced apoptosis
    • Williams TA, Monticone S, Crudo V, Warth R, Veglio F, Mulatero P. Visinin-like 1 is upregulated in aldosterone-producing adenomas with KCNJ5 mutations and protects from calcium-induced apoptosis. Hypertension. 2012;59:833-839.
    • (2012) Hypertension , vol.59 , pp. 833-839
    • Williams, T.A.1    Monticone, S.2    Crudo, V.3    Warth, R.4    Veglio, F.5    Mulatero, P.6
  • 70
    • 58849101212 scopus 로고    scopus 로고
    • Visinin-like proteins (VSNLs): Interaction partners and emerging functions in signal transduction of a subfamily of neuronal Ca2+-sensor proteins
    • Braunewell KH, Klein-Szanto AJ. Visinin-like proteins (VSNLs): interaction partners and emerging functions in signal transduction of a subfamily of neuronal Ca2+-sensor proteins. Cell Tissue Res. 2009;335: 301-316.
    • (2009) Cell Tissue Res , vol.335 , pp. 301-316
    • Braunewell, K.H.1    Klein-Szanto, A.J.2
  • 73
    • 78650520052 scopus 로고    scopus 로고
    • The Wnt/β-catenin pathway in adrenocortical development and cancer
    • El Wakil A, Lalli E. The Wnt/β-catenin pathway in adrenocortical development and cancer. Mol Cell Endocrinol. 2011;332:32-37.
    • (2011) Mol Cell Endocrinol , vol.332 , pp. 32-37
    • El Wakil, A.1    Lalli, E.2
  • 74
    • 84857118216 scopus 로고    scopus 로고
    • Wnt/β-catenin signalling in adrenal physiology and tumour development
    • Berthon A, Martinez A, Bertherat J, Val P. Wnt/β-catenin signalling in adrenal physiology and tumour development. Mol Cell Endocrinol. 2012; 351:87-95.
    • (2012) Mol Cell Endocrinol , vol.351 , pp. 87-95
    • Berthon, A.1    Martinez, A.2    Bertherat, J.3    Val, P.4
  • 77
    • 38049130282 scopus 로고    scopus 로고
    • Frequent mutations of β-catenin gene in sporadic secreting adrenocortical adenomas
    • Tadjine M, Lampron A, Ouadi L, Bourdeau I. Frequent mutations of β-catenin gene in sporadic secreting adrenocortical adenomas. Clin Endocrinol (Oxf). 2008;68:264-270.
    • (2008) Clin Endocrinol (Oxf) , vol.68 , pp. 264-270
    • Tadjine, M.1    Lampron, A.2    Ouadi, L.3    Bourdeau, I.4
  • 79
    • 70350578581 scopus 로고    scopus 로고
    • Targeted disruption of Sonic Hedgehog in the mouse adrenal leads to adrenocortical hypoplasia
    • Ching S, Vilain E. Targeted disruption of Sonic Hedgehog in the mouse adrenal leads to adrenocortical hypoplasia. Genesis. 2009;47: 628-637.
    • (2009) Genesis , vol.47 , pp. 628-637
    • Ching, S.1    Vilain, E.2
  • 80
    • 77149175960 scopus 로고    scopus 로고
    • Progenitor cell expansion and organ size of mouse adrenal is regulated by sonic hedgehog
    • Huang CC, Miyagawa S, Matsumaru D, Parker KL, Yao HH. Progenitor cell expansion and organ size of mouse adrenal is regulated by sonic hedgehog. Endocrinology. 2010;151:1119-1128.
    • (2010) Endocrinology , vol.151 , pp. 1119-1128
    • Huang, C.C.1    Miyagawa, S.2    Matsumaru, D.3    Parker, K.L.4    Yao, H.H.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.