Overexpression of human Cripto-1 in transgenic mice delays mammary gland development and differentiation and induces mammary tumorigenesis

American Journal of Pathology

Volumn 167, Issue 2, 2005, Pages 585-597

  Sun, Youping ^a   Strizzi, Luigi ^a   Raafat, Ahmed ^a   Hirota, Morihisa ^a   Bianco, Caterina ^a   Feigenbaum, Lionel ^b   Kenney, Nicholas ^a   Wechselberger, Christian ^c   Callahan, Robert ^a   Salomon, David S ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b SAIC FREDERICK INC   (United States)

^c Upper Austrian Research GmbH   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA TUBULIN; BETA CATENIN; CCAAT ENHANCER BINDING PROTEIN DELTA; GLYCOPROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN CRIPTO 1; PROTEIN KINASE B; STAT3 PROTEIN; UNCLASSIFIED DRUG; WNT PROTEIN; AKT1 PROTEIN, HUMAN; EPIDERMAL GROWTH FACTOR; MEMBRANE PROTEIN; MILK PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE KINASE; ONCOPROTEIN; PROTEIN SERINE THREONINE KINASE; TDGF1 PROTEIN, HUMAN; TUMOR PROTEIN; WHEY ACIDIC PROTEINS;

ADENOSQUAMOUS CARCINOMA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BREAST CARCINOGENESIS; BREAST DEVELOPMENT; BREAST HYPERPLASIA; BREAST TUMOR; CELL DIFFERENTIATION; CELL PROLIFERATION; CONTROLLED STUDY; CRIPTO 1 GENE; ENZYME PHOSPHORYLATION; FEMALE; GENE; GENE OVEREXPRESSION; HISTOPATHOLOGY; HUMAN; IMMUNOHISTOCHEMISTRY; INVOLUTION; LACTATION; MOUSE; MULTIPARA; NONHUMAN; POLYMERASE CHAIN REACTION; PREGNANCY; PRIORITY JOURNAL; TISSUE SPECIFICITY; TRANSGENIC MOUSE; WESTERN BLOTTING; ANIMAL; EXPERIMENTAL NEOPLASM; GENETICS; METABOLISM; PARITY; PATHOLOGY; PHOSPHORYLATION; PROMOTER REGION; SURVIVAL RATE; UDDER;

ANIMALS; APOPTOSIS; CELL DIFFERENTIATION; CELL PROLIFERATION; EPIDERMAL GROWTH FACTOR; FEMALE; HUMANS; LACTATION; MAMMARY GLANDS, ANIMAL; MAMMARY NEOPLASMS, EXPERIMENTAL; MEMBRANE GLYCOPROTEINS; MICE; MICE, TRANSGENIC; MILK PROTEINS; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; NEOPLASM PROTEINS; PARITY; PHOSPHORYLATION; PREGNANCY; PROMOTER REGIONS (GENETICS); PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; SURVIVAL RATE;

EID: 25144441897     PISSN: 00029440     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-9440(10)63000-3     Document Type: Article

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