In vitro release of aldosterone and cortisol in human adrenal adenomas correlates to mrna expression of steroidogenic enzymes for genes CYP11B2 and CYP17

World Journal of Surgery

Volumn 25, Issue 7, 2001, Pages 957-966

  Enberg, Ulla ^a   Farnebo, Lars Ove ^a   Wedell, Anna ^a   Gröndal, Staffan ^a   Thorén, Marja ^a   Grimelius, Lars ^a   Kjellman, Magnus ^a   Bäckdahl, Martin ^a   Hamberger, Bertil ^a  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

ALDOSTERONE; ALDOSTERONE SYNTHASE; CATECHOLAMINE; GENE PRODUCT; HYDROCORTISONE; MESSENGER RNA; STEROID; STEROID 11BETA MONOOXYGENASE; STEROID 17ALPHA MONOOXYGENASE; STEROID 18 HYDROXYLASE; STEROID 21 MONOOXYGENASE; UNCLASSIFIED DRUG;

ADRENAL CORTEX ADENOMA; ADRENAL TUMOR; ALDOSTERONE BLOOD LEVEL; ALDOSTERONE RELEASE; ARTICLE; CATECHOLAMINE URINE LEVEL; COMPUTER ASSISTED TOMOGRAPHY; CUSHING DISEASE; GENE EXPRESSION; GENE PROBE; GENE SEQUENCE; GENETIC CODE; HUMAN; HYDROCORTISONE RELEASE; IN VITRO STUDY; PATHOPHYSIOLOGY; PRIMARY HYPERALDOSTERONISM; SEQUENCE ANALYSIS; STEROID RELEASE; STEROIDOGENESIS;

ADRENAL CORTEX NEOPLASMS; ADRENOCORTICAL ADENOMA; ADULT; AGED; ALDOSTERONE; ALDOSTERONE SYNTHASE; CUSHING SYNDROME; FEMALE; HUMANS; HYDROCORTISONE; HYPERALDOSTERONISM; IN SITU HYBRIDIZATION; MALE; MIDDLE AGED; MOLECULAR PROBE TECHNIQUES; RNA, MESSENGER; STEROID 11-BETA-HYDROXYLASE; STEROID 17-ALPHA-HYDROXYLASE;

EID: 0034911606     PISSN: 03642313     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00268-001-0035-2     Document Type: Article

References (14)

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5. Stromal fibroblasts adjacent to invasive thyroid tumors: Expression of gelatinase A but not stromelysin 3 mRNA
6. Tumor-specific decreased expression of calcium sensing receptor messenger ribonucleic acid in sporadic primary hyperparathyroidism
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8. Complete nucleotide sequence of two steroid 21-hydroxylase genes tandemly arranged in human chromosome: A pseudogene and a genuine gene
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11. Cytochrome P450c17 (steroid 17 alpha-hydroxylase/17,20 lyase): Cloning of human adrenal and testis cDNAs indicates the same gene is expressed in both tissues
12. Characterization of complementary deoxyribonucleic acid for human adrenocortical 17 alpha-hydroxylase: A probe for analysis of 17 alpha-hydroxylase deficiency
13. Cloning and sequence of the human gene for P450c17 (steroid 17 alpha-hydroxylase/17,20 lyase): Similarity with the gene for P450c21
14. Cloning of cDNA encoding steroid 11 beta-hydroxylase (P450c11)