Invalidation of TASK1 potassium channels disrupts adrenal gland zonation and mineralocorticoid homeostasis

EMBO Journal

Volumn 27, Issue 1, 2008, Pages 179-187

  Heitzmann, Dirk ^a   Derand, Renaud ^b   Jungbauer, Stefan ^a   Bandulik, Sascha ^a   Sterner, Christina ^a   Schweda, Frank ^a   El Wakil, Abeer ^b   Lalli, Enzo ^b   Guy, Nicolas ^b   Mengual, Raymond ^c   Reichold, Markus ^a   Tegtmeier, Ines ^a   Bendahhou, Saïd ^b   Gomez Sanchez, Celso E ^d   Isabel Aller, M ^e   Wisden, William ^f   Weber, Achim ^g   Lesage, Florian ^b   Warth, Richard ^a   Barhanin, Jacques ^b  

^a UNIVERSITY OF REGENSBURG   (Germany)

^b INSTITUT DE PHARMACOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

^c UNIVERSITY HOSPITAL OF NICE   (France)

^d VETERANS AFFAIRS MEDICAL CENTER   (United States)

^e INSTITUTO DE NEUROCIENCIAS   (Spain)

^f UNIVERSITY OF ABERDEEN   (United Kingdom)

^g UNIVERSITY HOSPITAL ZURICH   (Switzerland)

Author keywords

Aldosterone; Arterial hypertension; KCNK3; KCNK9; TASK 1

Indexed keywords

ALDOSTERONE; ALDOSTERONE SYNTHASE; ENDOCRINE DISRUPTOR; GLUCOCORTICOID; MINERALOCORTICOID; POTASSIUM CHANNEL; POTASSIUM CHANNEL KCNK3; POTASSIUM CHANNEL TASK1; RENIN; UNCLASSIFIED DRUG;

ADRENAL CELL; ADRENAL CORTEX; ADRENAL GLAND; ADULTHOOD; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENDOCRINE FUNCTION; FEMALE; HOMEOSTASIS; HYPERALDOSTERONISM; HYPERTENSION; HYPOKALEMIA; MOLECULAR DYNAMICS; MOUSE; NONHUMAN; PATCH CLAMP; PHENOTYPE; PRIORITY JOURNAL; SALT INTAKE; ZONA GLOMERULOSA; ZONATION;

ADRENAL GLANDS; ALDOSTERONE; ANIMALS; FEMALE; HOMEOSTASIS; HYPERALDOSTERONISM; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MINERALOCORTICOIDS; NERVE TISSUE PROTEINS; POTASSIUM; POTASSIUM CHANNELS, TANDEM PORE DOMAIN; RENIN;

MUS;

EID: 38049015880     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/sj.emboj.7601934     Document Type: Article

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