Deletion of beta-2-microglobulin ameliorates spinal cord lesion load and promotes recovery of brainstem NAA levels in a murine model of multiple sclerosis

Brain Pathology

Volumn 22, Issue 5, 2012, Pages 698-708

  Denic, Aleksandar ^a   Pirko, Istvan ^a   Wootla, Bharath ^a   Bieber, Allan ^a   MacUra, Slobodan ^a   Rodriguez, Moses ^a  

^a MAYO CLINIC   (United States)

Author keywords

axonal loss; beta 2 microglobulin; demyelination; N acetyl aspartate (NAA); Theiler's murine encephalomyelitis virus (TMEV)

Indexed keywords

BETA 2 MICROGLOBULIN; N ACETYLASPARTIC ACID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN LEVEL; BRAIN STEM; CARDIOVIRUS INFECTION; CD8+ T LYMPHOCYTE; CONTROLLED STUDY; CONVALESCENCE; DEMYELINATION; DISEASE COURSE; GENE DELETION; IMMUNOHISTOCHEMISTRY; IMMUNOPATHOLOGY; MORPHOMETRICS; MOUSE; MULTIPLE SCLEROSIS; MURINE ENCEPHALOMYELITIS VIRUS; MYELINATED NERVE; NERVE FIBER DEGENERATION; NEUROPATHOLOGY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; REMYELINIZATION; SPINAL CORD LESION; SPINAL CORD NERVE CELL;

ANIMALS; ANTIGENS, CD8; ASPARTIC ACID; AXONS; BETA 2-MICROGLOBULIN; BRAIN; BRAIN STEM; DISEASE MODELS, ANIMAL; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MICE; MICE, TRANSGENIC; MULTIPLE SCLEROSIS; RECOVERY OF FUNCTION; SPINAL CORD; THEILOVIRUS; TIME FACTORS;

EID: 84865451385     PISSN: 10156305     EISSN: 17503639     Source Type: Journal    
DOI: 10.1111/j.1750-3639.2012.00576.x     Document Type: Article

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