Brainstem 1H Nuclear Magnetic Resonance (NMR) spectroscopy: Marker of demyelination and repair in spinal cord

Annals of Neurology

Volumn 66, Issue 4, 2009, Pages 559-564

  Denic, Aleksandar ^a   Bieber, Allan ^a   Warrington, Arthur ^a   Mishra, Prasanna K ^a   Macura, Slobodan ^a   Rodriguez, Moses ^a  

^a Mayo Clinic   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

N ACETYLASPARTIC ACID; ASPARTIC ACID; BIOLOGICAL MARKER; DIAGNOSTIC AGENT; DRUG DERIVATIVE; N-ACETYLASPARTATE; PROTON;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN STEM; CONTROLLED STUDY; CONVALESCENCE; DEMYELINATION; DISEASE MARKER; FRIEND LEUKEMIA VIRUS; IN VIVO STUDY; MOUSE; MOUSE STRAIN; NERVE FIBER; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; REMYELINIZATION; SPINAL CORD INJURY; ANIMAL; CEREBROSPINAL FLUID; COMPARATIVE STUDY; DEMYELINATING DISEASE; GROWTH, DEVELOPMENT AND AGING; ISOLATION AND PURIFICATION; METABOLISM; METHODOLOGY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PATHOLOGY; PHYSIOLOGY; VIROLOGY;

ANIMALS; ASPARTIC ACID; BIOLOGICAL MARKERS; BRAIN STEM; DEMYELINATING DISEASES; FRIEND MURINE LEUKEMIA VIRUS; MAGNETIC RESONANCE SPECTROSCOPY; MICE; PROTONS; SPINAL CORD INJURIES;

EID: 70449370458     PISSN: 03645134     EISSN: 15318249     Source Type: Journal    
DOI: 10.1002/ana.21758     Document Type: Article

References (14)

1. Ure D, Rodriguez M. Extensive injury of descending neurons demonstrated by retrograde labeling in a virus-induced murine model of chronic inflammatory demyelination. J Neuropathol Exp Neurol 2000;59:664-678. (Pubitemid 30626737)
2. Pirko I, Johnson A, Gamez J, et al. Disappearing "T1 black holes" in an animal model of multiple sclerosis. Front Biosci 2004;9:1222-1227.
3. Bieber AJ, Ure DR, Rodriguez M. Genetically dominant spinal cord repair in a murine model of chronic progressive multiple sclerosis. J Neuropathol Exp Neurol 2005;64:46-57. (Pubitemid 40189478)
4. Govindaraju V, Young K, Maudsley AA. Proton NMR chemical shifts and coupling constants for brain metabolites. NMR Biomed 2000;13:129-153. (Pubitemid 30414704)
5. Manganas LN, Zhang X, Li Y, et al. Magnetic resonance spectroscopy identifies neural progenitor cells in the live human brain. Science 2007;318:980-985. (Pubitemid 350098995)
6. Drost DJ, Riddle WR, Clarke GD. Proton magnetic resonance spectroscopy in the brain: report of AAPM MR task group #9. Med Phys 2002;29:2177-2197. (Pubitemid 35051968)
7. Filippi M, Tortorella C, Bozzali M. Normal-appearing white matter changes in multiple sclerosis: the contribution of magnetic resonance techniques. Mult Scler 1999;5:273-282. (Pubitemid 29405625)
8. Rooney WD, Goodkin DE, Schuff N et al. 1H MRSI of normal appearing white matter in multiple sclerosis. Mult Scler 1997;3:231-237. (Pubitemid 27478587)
9. Roser W, Hagberg G, Mader I, et al. Proton MRS of gadolinium-enhancing MS plaques and metabolic changes in normal-appearing white matter. Magn Reson Med 1995;33:811-817.
10. Tourbah A, Stievenart JL, Iba-Zizen MT, et al. In vivo localized NMR proton spectroscopy of normal appearing white matter in patients with multiple sclerosis. J Neuroradiol 1996;23:49-55.
11. De Stefano N, Matthews PM, Fu L, et al. Axonal damage correlates with disability in patients with relapsing-remitting multiple sclerosis. Results of a longitudinal magnetic resonance spectroscopy study. Brain 1998;121(Pt 8):1469-1477.
12. McGavern DB, Murray PD, Rivera-Quinones C, et al. Axonal loss results in spinal cord atrophy, electrophysiological abnormalities and neurological deficits following demyelination in a chronic inflammatory model of multiple sclerosis. Brain 2000; 123(Pt 3):519-531. (Pubitemid 30099537)
13. Howe CL, Adelson JD, Rodriguez M. Absence of perforin expression confers axonal protection despite demyelination. Neurobiol Dis 2007;25:354-359. (Pubitemid 46124015)
14. Beck JA, Lloyd S, Hafezparast M, et al. Genealogies of mouse inbred strains. Nat Genet 2000;24:23-25.