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Volumn 115, Issue 21, 2002, Pages 4037-4051

The spatio-temporal organization of DNA relplication sites is identical in primary, immortalized and transformed mammalian cells

Author keywords

DNA replication patterns; Minichromosome maintenance proteins; Nuclear lamin proteins; Primary and transformed mammalian cells; Retinoblastoma protein; Senescence

Indexed keywords

BIOTIN; BROXURIDINE; CYCLINE; DNA; FLUORESCENT DYE; LAMIN; MINICHROMOSOME MAINTENANCE PROTEIN; NUCLEASE; PURINE; REPLICATION PROTEIN A; RETINOBLASTOMA PROTEIN; SINGLE STRANDED DNA; STREPTAVIDIN; DNA BINDING PROTEIN; MCM2 PROTEIN, MAMMALIAN; NUCLEAR PROTEIN; RPA1 PROTEIN, HUMAN;

EID: 0036860727     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: 10.1242/jcs.00087     Document Type: Review
Times cited : (150)

References (113)
  • 1
    • 0032830639 scopus 로고    scopus 로고
    • Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2
    • Amir, R. E., van den Veyver, I. B., Wan, M., Tran, C. Q., Francke, U. and Zoghbi, H. Y. (1999). Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2. Nat. Genet. 23, 185-188.
    • (1999) Nat. Genet. , vol.23 , pp. 185-188
    • Amir, R.E.1    van den Veyver, I.B.2    Wan, M.3    Tran, C.Q.4    Francke, U.5    Zoghbi, H.Y.6
  • 2
    • 0026593194 scopus 로고
    • Cellular localization and T antigen binding of the retinoblastoma protein
    • Bartek, J., Vojtesek, B., Grand, R. J., Gallimore, P. H. and Lane, D. P. (1992). Cellular localization and T antigen binding of the retinoblastoma protein. Oncogene 7, 101-108.
    • (1992) Oncogene , vol.7 , pp. 101-108
    • Bartek, J.1    Vojtesek, B.2    Grand, R.J.3    Gallimore, P.H.4    Lane, D.P.5
  • 4
    • 0036374278 scopus 로고    scopus 로고
    • Regulating the mammalian genome: The role of nuclear architecture
    • Berezney, R. (2002). Regulating the mammalian genome: the role of nuclear architecture. Adv. Enzyme Regul. 42, 39-52.
    • (2002) Adv. Enzyme Regul. , vol.42 , pp. 39-52
    • Berezney, R.1
  • 5
    • 0035796407 scopus 로고    scopus 로고
    • Control of chromosomal DNA replication in the early Xenopus embryo
    • Blow, J. J. (2001). Control of chromosomal DNA replication in the early Xenopus embryo. EMBO J 20, 3293-3297.
    • (2001) EMBO J. , vol.20 , pp. 3293-3297
    • Blow, J.J.1
  • 7
    • 0023579723 scopus 로고
    • Existence of two populations of cyclin/proliferating cell nuclear antigen during the cell cycle: Association with DNA replication sites
    • Bravo, R. and Macdonald-Bravo, H. (1987). Existence of two populations of cyclin/proliferating cell nuclear antigen during the cell cycle: association with DNA replication sites. J. Cell Biol. 105, 1549-1554.
    • (1987) J. Cell Biol. , vol.105 , pp. 1549-1554
    • Bravo, R.1    Macdonald-Bravo, H.2
  • 8
    • 0024439444 scopus 로고
    • The retinoblastoma protein is phosphorylated during specific phases of the cell cycle
    • Buchkovich, K., Duffy, L. A. and Harlow, E. (1989). The retinoblastoma protein is phosphorylated during specific phases of the cell cycle. Cell 58, 1097-1105.
    • (1989) Cell , vol.58 , pp. 1097-1105
    • Buchkovich, K.1    Duffy, L.A.2    Harlow, E.3
  • 9
    • 0029120154 scopus 로고
    • Increased phosphorylation of histone H1 in mouse fibroblasts transformed with oncogenes or constitutively active mitogen-activated protein kinase kinase
    • Chadee, D. N., Taylor, W. R., Hurta, R. A., Allis, C. D., Wright, J. A. and Davie, J. R. (1995). Increased phosphorylation of histone H1 in mouse fibroblasts transformed with oncogenes or constitutively active mitogen-activated protein kinase kinase. J. Biol. Chem. 270, 20098-20105.
    • (1995) J. Biol. Chem. , vol.270 , pp. 20098-20105
    • Chadee, D.N.1    Taylor, W.R.2    Hurta, R.A.3    Allis, C.D.4    Wright, J.A.5    Davie, J.R.6
  • 10
    • 0033609882 scopus 로고    scopus 로고
    • Increased Ser-10 phosphorylation of histone H3 in mitogen-stimulated and oncogene-transformed mouse fibroblasts
    • Chadee, D. N., Hendzel, M. J., Tylipski, C. P., Allis, C. D., Bazett-jones, D. P., Wright, J. A. and Davie, J. R. (1999). Increased Ser-10 phosphorylation of histone H3 in mitogen-stimulated and oncogene-transformed mouse fibroblasts. J. Biol. Chem. 274, 24914-24920.
    • (1999) J. Biol. Chem. , vol.274 , pp. 24914-24920
    • Chadee, D.N.1    Hendzel, M.J.2    Tylipski, C.P.3    Allis, C.D.4    Bazett-jones, D.P.5    Wright, J.A.6    Davie, J.R.7
  • 11
    • 0030770835 scopus 로고    scopus 로고
    • Human DNA-(cytosine-5) methyltransferase-PCNA complex as a target for p21WAF1
    • Chuang, L. S., Ian, H. I., Koh, T. W., Ng, H. H., Xu, G. and Li, B. F. (1997). Human DNA-(cytosine-5) methyltransferase-PCNA complex as a target for p21WAF1. Science 277, 1996-2000.
    • (1997) Science , vol.277 , pp. 1996-2000
    • Chuang, L.S.1    Ian, H.I.2    Koh, T.W.3    Ng, H.H.4    Xu, G.5    Li, B.F.6
  • 13
    • 0034650581 scopus 로고    scopus 로고
    • Genetic alterations disrupting the nuclear localization of the retinoblastoma-related gene RB2/p130 in human tumor cell lines and primary tumors
    • Cinti, C., Claudio, P. P., Howard, C. M., Neri, L. M., Fu, Y., Leoncini, L., Tosi, G. M., Maraldi, N. M. and Giordano, A. (2000). Genetic alterations disrupting the nuclear localization of the retinoblastoma-related gene RB2/p130 in human tumor cell lines and primary tumors. Cancer Res. 60, 83-389.
    • (2000) Cancer Res. , vol.60 , pp. 383-389
    • Cinti, C.1    Claudio, P.P.2    Howard, C.M.3    Neri, L.M.4    Fu, Y.5    Leoncini, L.6    Tosi, G.M.7    Maraldi, N.M.8    Giordano, A.9
  • 14
    • 0034449502 scopus 로고    scopus 로고
    • Nuclear matrix proteins as cancer markers
    • Davido, T. and Getzenberg, R. H. (2000). Nuclear matrix proteins as cancer markers. J. Cell Biochem. 79, 136-141.
    • (2000) J. Cell Biochem. , vol.79 , pp. 136-141
    • Davido, T.1    Getzenberg, R.H.2
  • 15
    • 0032505722 scopus 로고    scopus 로고
    • DNA content and chromatin texture of benzo[α]pyrene-transformed human breast epithelial cells as assessed by image analysis
    • de Campos Vidal, B., Russo, J. and Mello, M. L. (1998). DNA content and chromatin texture of benzo[α]pyrene-transformed human breast epithelial cells as assessed by image analysis. Exp. Cell Res. 244, 77-82.
    • (1998) Exp. Cell Res. , vol.244 , pp. 77-82
    • de Campos Vidal, B.1    Russo, J.2    Mello, M.L.3
  • 16
    • 0031730896 scopus 로고    scopus 로고
    • Regulation of mammalian replication origin usage in Xenopus egg extract
    • Dimitrova, D. S. and Gilbert, D. M. (1998). Regulation of mammalian replication origin usage in Xenopus egg extract. J. Cell Sci. 111, 2989-2998.
    • (1998) J. Cell Sci. , vol.111 , pp. 2989-2998
    • Dimitrova, D.S.1    Gilbert, D.M.2
  • 17
    • 0033369515 scopus 로고    scopus 로고
    • The spatial position and replication timing of chromosomal domains are both established in early G1 phase
    • Dimitrova, D. S. and Gilbert, D. M. (1999). The spatial position and replication timing of chromosomal domains are both established in early G1 phase. Mol. Cell 4, 983-993.
    • (1999) Mol. Cell , vol.4 , pp. 983-993
    • Dimitrova, D.S.1    Gilbert, D.M.2
  • 18
    • 0034141739 scopus 로고    scopus 로고
    • Stability and nuclear distribution of mammalian replication protein A heterotrimeric complex
    • Dimitrova, D. S. and Gilbert, D. M. (2000a). Stability and nuclear distribution of mammalian replication protein A heterotrimeric complex. Exp. Cell Res. 254, 321-327.
    • (2000) Exp. Cell Res. , vol.254 , pp. 321-327
    • Dimitrova, D.S.1    Gilbert, D.M.2
  • 19
    • 0034306184 scopus 로고    scopus 로고
    • Temporally coordinated assembly and disassembly of replication factories in the absence of DNA synthesis
    • Dimitrova, D. S. and Gilbert, D. M. (2000b). Temporally coordinated assembly and disassembly of replication factories in the absence of DNA synthesis. Nat. Cell Biol. 2, 686-694.
    • (2000) Nat. Cell Biol. , vol.2 , pp. 686-694
    • Dimitrova, D.S.1    Gilbert, D.M.2
  • 20
    • 0033598133 scopus 로고    scopus 로고
    • Mcm2, but not RPA, is a component of the mammalian early G1-phase prereplication complex
    • Dimitrova, D. S., Todorov, I. T., Melendy, T. and Gilbert, D. M. (1999). Mcm2, but not RPA, is a component of the mammalian early G1-phase prereplication complex. J. Cell Biol. 146, 709-722.
    • (1999) J. Cell Biol. , vol.146 , pp. 709-722
    • Dimitrova, D.S.1    Todorov, I.T.2    Melendy, T.3    Gilbert, D.M.4
  • 22
    • 0024114727 scopus 로고
    • Use of restriction endonucleases and exonuclease III to expose halogenated pyrimidines for immunochemical staining
    • Dolbeare, F. and Gray, J. W. (1988). Use of restriction endonucleases and exonuclease III to expose halogenated pyrimidines for immunochemical staining. Cytometry 9, 631-635.
    • (1988) Cytometry , vol.9 , pp. 631-635
    • Dolbeare, F.1    Gray, J.W.2
  • 23
    • 0032146274 scopus 로고    scopus 로고
    • The regulation of E2F by pRB-family proteins
    • Dyson, N. (1998). The regulation of E2F by pRB-family proteins. Genes Dev. 12, 2245-2262.
    • (1998) Genes Dev. , vol.12 , pp. 2245-2262
    • Dyson, N.1
  • 24
    • 0026317881 scopus 로고
    • High expression of the DNA methyltransferase gene characterizes human neoplastic cells and progression stages of colon cancer
    • El-Deiry, W. S., Nelkin, B. D., Celano, P., Yen, R. W., Falco, J. P., Hamilton, S. R. and Baylin, S. B. (1991). High expression of the DNA methyltransferase gene characterizes human neoplastic cells and progression stages of colon cancer. Proc. Natl. Acad Sci. USA 88, 3470-3474.
    • (1991) Proc. Natl. Acad Sci. USA , vol.88 , pp. 3470-3474
    • El-Deiry, W.S.1    Nelkin, B.D.2    Celano, P.3    Yen, R.W.4    Falco, J.P.5    Hamilton, S.R.6    Baylin, S.B.7
  • 25
    • 0034948814 scopus 로고    scopus 로고
    • Differential regulation of retinoblastoma tumor suppressor protein by G(1) cyclin-dependent kinase complexes in vivo
    • Ezhevsky, S. A., Ho, A., Becker-Hapak, M., Davis, P. K. and Dowdy, S. F. (2001). Differential regulation of retinoblastoma tumor suppressor protein by G(1) cyclin-dependent kinase complexes in vivo. Mol. Cell Biol. 21, 4773-4784.
    • (2001) Mol. Cell Biol. , vol.21 , pp. 4773-4784
    • Ezhevsky, S.A.1    Ho, A.2    Becker-Hapak, M.3    Davis, P.K.4    Dowdy, S.F.5
  • 26
    • 0030964894 scopus 로고    scopus 로고
    • Genome replication in early mouse embryos follows a defined temporal and spatial order
    • Ferreira, J. and Carmo-Fonseca, M. (1997). Genome replication in early mouse embryos follows a defined temporal and spatial order. J. Cell Sci. 110, 889-897.
    • (1997) J. Cell Sci. , vol.110 , pp. 889-897
    • Ferreira, J.1    Carmo-Fonseca, M.2
  • 27
    • 0031951650 scopus 로고    scopus 로고
    • p53 and RPA are sequestered in viral replication centers in the nuclei of cells infected with human cytomegalovirus
    • Fortunato, E. A. and Spector, D. H. (1998). p53 and RPA are sequestered in viral replication centers in the nuclei of cells infected with human cytomegalovirus. J. Virol. 72, 2033-2039.
    • (1998) J. Virol. , vol.72 , pp. 2033-2039
    • Fortunato, E.A.1    Spector, D.H.2
  • 28
    • 0025906795 scopus 로고
    • Spatial and temporal distribution of DNA replication sites localized by immunofluorescence and confocal microscopy in mouse fibroblasts
    • Fox, M. H., Arndt-Jovin, D. J., Jovin, T. M., Baumann, P. H. and Robert-Nicoud, M. (1991). Spatial and temporal distribution of DNA replication sites localized by immunofluorescence and confocal microscopy in mouse fibroblasts. J. Cell Sci. 99, 247-253.
    • (1991) J. Cell Sci. , vol.99 , pp. 247-253
    • Fox, M.H.1    Arndt-Jovin, D.J.2    Jovin, T.M.3    Baumann, P.H.4    Robert-Nicoud, M.5
  • 29
    • 0031954845 scopus 로고    scopus 로고
    • Molecular-cytogenetic characterization of the Vicia faba genome - Heterochromatin differentiation, replication patterns and sequence localization
    • Fuchs, J., Strehl, S., Brandes, A., Schweizer, D. and Schubert, I. (1998). Molecular-cytogenetic characterization of the Vicia faba genome - heterochromatin differentiation, replication patterns and sequence localization. Chromosome Res. 6, 219-230.
    • (1998) Chromosome Res. , vol.6 , pp. 219-230
    • Fuchs, J.1    Strehl, S.2    Brandes, A.3    Schweizer, D.4    Schubert, I.5
  • 30
    • 0032462539 scopus 로고    scopus 로고
    • Sequence of DNA replication in Allium fistulosum chromosomes during S- phase
    • Fujishige, I. and Taniguchi, K. (1998). Sequence of DNA replication in Allium fistulosum chromosomes during S- phase. Chromosome Res. 6, 611-619.
    • (1998) Chromosome Res. , vol.6 , pp. 611-619
    • Fujishige, I.1    Taniguchi, K.2
  • 32
    • 0026058874 scopus 로고
    • The retinoblastoma gene product regulates progression through the G1 phase of the cell cycle
    • Goodrich, D. W., Wang, N. P., Qian, Y. W., Lee, E. Y. and Lee, W. H. (1991). The retinoblastoma gene product regulates progression through the G1 phase of the cell cycle. Cell 67, 293-302.
    • (1991) Cell , vol.67 , pp. 293-302
    • Goodrich, D.W.1    Wang, N.P.2    Qian, Y.W.3    Lee, E.Y.4    Lee, W.H.5
  • 34
    • 0034641878 scopus 로고    scopus 로고
    • Rb and p130 regulate RNA polymerase I transcription: Rb disrupts the interaction between UBF and SL-1
    • Hannan, K. M., Hannan, R. D., Smith, S. D., Jefferson, L. S., Lun, M. and Rothblum, L. I. (2000). Rb and p130 regulate RNA polymerase I transcription: Rb disrupts the interaction between UBF and SL-1. Oncogene 19, 4988-4999.
    • (2000) Oncogene , vol.19 , pp. 4988-4999
    • Hannan, K.M.1    Hannan, R.D.2    Smith, S.D.3    Jefferson, L.S.4    Lun, M.5    Rothblum, L.I.6
  • 36
    • 0344622606 scopus 로고
    • The serial cultivation of human diploid cell strains
    • Hayflick, L. and Moorhead, P. S. (1961). The serial cultivation of human diploid cell strains. Exp. Cell Res. 25, 585-621.
    • (1961) Exp. Cell Res. , vol.25 , pp. 585-621
    • Hayflick, L.1    Moorhead, P.S.2
  • 37
    • 0029909105 scopus 로고    scopus 로고
    • Increased histone H1 phosphorylation and relaxed chromatin structure in Rb-deficient fibroblasts
    • Herrera, R. E., Chen, F. and Weinberg, R. A. (1996). Increased histone H1 phosphorylation and relaxed chromatin structure in Rb-deficient fibroblasts. Proc. Natl. Acad. Sci. USA 93, 11510-11515.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 11510-11515
    • Herrera, R.E.1    Chen, F.2    Weinberg, R.A.3
  • 38
    • 0036467506 scopus 로고    scopus 로고
    • Regulation of G(1) cell-cycle progression by oncogenes and tumor suppressor genes
    • Ho, A. and Dowdy, S. F. (2002). Regulation of G(1) cell-cycle progression by oncogenes and tumor suppressor genes. Curr. Opin. Genet. Dev. 12, 47-52.
    • (2002) Curr. Opin. Genet. Dev. , vol.12 , pp. 47-52
    • Ho, A.1    Dowdy, S.F.2
  • 39
    • 0020980777 scopus 로고
    • Phosphorylation of H1 histones
    • Hohmann, P. (1983). Phosphorylation of H1 histones. Mol. Cell Biochem. 57, 81-92.
    • (1983) Mol. Cell Biochem. , vol.57 , pp. 81-92
    • Hohmann, P.1
  • 40
    • 0028038215 scopus 로고
    • Replication factories and nuclear bodies: The ultrastructural characterization of replication sites during the cell cycle
    • Hozak, P., Jackson, D. A. and Cook, P. R. (1994). Replication factories and nuclear bodies: the ultrastructural characterization of replication sites during the cell cycle. J. Cell Sci. 107, 2191-2202.
    • (1994) J. Cell Sci. , vol.107 , pp. 2191-2202
    • Hozak, P.1    Jackson, D.A.2    Cook, P.R.3
  • 41
    • 0026651916 scopus 로고
    • Eukaryotic DNA replication is a topographically ordered process
    • Humbert, C.. and Usson, Y. (1992). Eukaryotic DNA replication is a topographically ordered process. Cytometry 13, 603-614.
    • (1992) Cytometry , vol.13 , pp. 603-614
    • Humbert, C.1    Usson, Y.2
  • 42
    • 0026786341 scopus 로고
    • Intranuclear co-location of newly replicated DNA and PCNA by simultaneous immunofluorescent labelling and confocal microscopy in MCF-7 cells
    • Humbert, C., Santisteban, M. S., Usson, Y. and Robert-Nicoud, M. (1992). Intranuclear co-location of newly replicated DNA and PCNA by simultaneous immunofluorescent labelling and confocal microscopy in MCF-7 cells. J. Cell Sci. 103, 97-103.
    • (1992) J. Cell Sci. , vol.103 , pp. 97-103
    • Humbert, C.1    Santisteban, M.S.2    Usson, Y.3    Robert-Nicoud, M.4
  • 43
    • 0029095975 scopus 로고
    • S-phase progression in synchronized human cells
    • Jackson, D. A. (1995). S-phase progression in synchronized human cells. Exp. Cell Res. 220, 62-70.
    • (1995) Exp. Cell Res. , vol.220 , pp. 62-70
    • Jackson, D.A.1
  • 44
    • 0028308290 scopus 로고
    • Sites in human nuclei where DNA damaged by ultraviolet light is repaired: Visualization and localization relative to the nucleoskeleton
    • Jackson, D. A., Balajee, A. S., Mullenders, L. and Cook, P. R. (1994). Sites in human nuclei where DNA damaged by ultraviolet light is repaired: visualization and localization relative to the nucleoskeleton. J. Cell Sci. 107, 1745-1752.
    • (1994) J. Cell Sci. , vol.107 , pp. 1745-1752
    • Jackson, D.A.1    Balajee, A.S.2    Mullenders, L.3    Cook, P.R.4
  • 45
    • 0022971594 scopus 로고
    • DNA methyltransferase levels in tumorigenic and nontumorigenic cells in culture
    • Kautiainen, T. L. and Jones, P. A. (1986). DNA methyltransferase levels in tumorigenic and nontumorigenic cells in culture. J. Biol. Chem. 261, 1594-1598.
    • (1986) J. Biol. Chem. , vol.261 , pp. 1594-1598
    • Kautiainen, T.L.1    Jones, P.A.2
  • 46
    • 0034669029 scopus 로고    scopus 로고
    • Nuclear organization of DNA replication in primary mammalian cells
    • Kennedy, B. K., Barbie, D. A., Classon, M., Dyson, N. and Harlow, E. (2000). Nuclear organization of DNA replication in primary mammalian cells. Genes Dev. 14, 2855-2868.
    • (2000) Genes Dev. , vol.14 , pp. 2855-2868
    • Kennedy, B.K.1    Barbie, D.A.2    Classon, M.3    Dyson, N.4    Harlow, E.5
  • 47
    • 0026329722 scopus 로고
    • The timing of the formation and usage of replicase clusters in S-phase nuclei of human diploid fibroblasts
    • Kill, I. R., Bridger, J. M., Campbell, K. H., Maldonado, C. G. and Hutchison, C. J. (1991). The timing of the formation and usage of replicase clusters in S-phase nuclei of human diploid fibroblasts. J. Cell Sci. 100, 869-876.
    • (1991) J. Cell Sci. , vol.100 , pp. 869-876
    • Kill, I.R.1    Bridger, J.M.2    Campbell, K.H.3    Maldonado, C.G.4    Hutchison, C.J.5
  • 49
    • 0029161152 scopus 로고
    • Chromatin assembly factor 1 (CAF-1) colocalizes with replication foci in HeLa cell nuclei
    • Krude, T. (1995). Chromatin assembly factor 1 (CAF-1) colocalizes with replication foci in HeLa cell nuclei. Exp. Cell Res. 220, 304-311.
    • (1995) Exp. Cell Res. , vol.220 , pp. 304-311
    • Krude, T.1
  • 50
    • 0030043371 scopus 로고    scopus 로고
    • Human replication proteins hCdc21, hCdc46 and P1Mcm3 bind chromatin uniformly before S-phase and are displaced locally during DNA replication
    • Krude, T., Musahl, C., Laskey, R. A. and Knippers, R. (1996). Human replication proteins hCdc21, hCdc46 and P1Mcm3 bind chromatin uniformly before S-phase and are displaced locally during DNA replication. J. Cell Sci. 109, 309-318.
    • (1996) J. Cell Sci. , vol.109 , pp. 309-318
    • Krude, T.1    Musahl, C.2    Laskey, R.A.3    Knippers, R.4
  • 51
    • 0015955751 scopus 로고
    • An ultrastructural and radioautographic study of the evolution of the interphase nucleus in plant meristematic cells (Allium porrum)
    • Lafontaine, J. G. and Lord, A. (1974). An ultrastructural and radioautographic study of the evolution of the interphase nucleus in plant meristematic cells (Allium porrum). J. Cell Sci. 14, 263-287.
    • (1974) J. Cell Sci. , vol.14 , pp. 263-287
    • Lafontaine, J.G.1    Lord, A.2
  • 52
    • 0032562608 scopus 로고    scopus 로고
    • Structure and function in the nucleus
    • Lamond, A. I. and Earnshaw, W. C. (1998). Structure and function in the nucleus. Science 280, 547-553.
    • (1998) Science , vol.280 , pp. 547-553
    • Lamond, A.I.1    Earnshaw, W.C.2
  • 53
    • 0026643471 scopus 로고
    • Nuclear distribution of PCNA during embryonic development in Xenopus laevis: A reinvestigation of early cell cycles
    • Leibovici, M., Monod, G., Geraudie, J., Bravo, R. and Mechali, M. (1992). Nuclear distribution of PCNA during embryonic development in Xenopus laevis: a reinvestigation of early cell cycles. J. Cell Sci. 102, 63-69.
    • (1992) J. Cell Sci. , vol.102 , pp. 63-69
    • Leibovici, M.1    Monod, G.2    Geraudie, J.3    Bravo, R.4    Mechali, M.5
  • 54
    • 0026439115 scopus 로고
    • A targeting sequence directs DNA methyltransferase to sites of DNA replication in mammalian nuclei
    • Leonhardt, H., Page, A. W., Weier, H. U. and Bestor, T. H. (1992). A targeting sequence directs DNA methyltransferase to sites of DNA replication in mammalian nuclei. Cell 71, 865-873.
    • (1992) Cell , vol.71 , pp. 865-873
    • Leonhardt, H.1    Page, A.W.2    Weier, H.U.3    Bestor, T.H.4
  • 56
    • 0034106643 scopus 로고    scopus 로고
    • Selective activation of pre-replication complexes in vitro at specific sites in mammalian nuclei
    • Li, C. J., Bogan, J. A., Natale, D. A. and DePamphilis, M. L. (2000). Selective activation of pre-replication complexes in vitro at specific sites in mammalian nuclei. J. Cell Sci. 113, 887-898.
    • (2000) J. Cell Sci. , vol.113 , pp. 887-898
    • Li, C.J.1    Bogan, J.A.2    Natale, D.A.3    DePamphilis, M.L.4
  • 58
    • 0028348459 scopus 로고
    • Generation and characterization of novel antibodies highly selective for phosphorylated linker histone H1 in Tetrahymena and HeLa cells
    • Lu, M. J., Dadd, C. A., Mizzen, C. A., Perry, C. A., McLachlan, D. R., Annunziato, A. T. and Allis, C. D. (1994). Generation and characterization of novel antibodies highly selective for phosphorylated linker histone H1 in Tetrahymena and HeLa cells. Chromosoma 103, 111-121.
    • (1994) Chromosoma , vol.103 , pp. 111-121
    • Lu, M.J.1    Dadd, C.A.2    Mizzen, C.A.3    Perry, C.A.4    McLachlan, D.R.5    Annunziato, A.T.6    Allis, C.D.7
  • 59
    • 0031951182 scopus 로고    scopus 로고
    • Functional inactivation of the retinoblastoma protein requires sequential modification by at least two distinct cyclin-cdk complexes
    • Lundberg, A. S. and Weinberg, R. A. (1998). Functional inactivation of the retinoblastoma protein requires sequential modification by at least two distinct cyclin-cdk complexes. Mol. Cell. Biol. 18, 753-761.
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 753-761
    • Lundberg, A.S.1    Weinberg, R.A.2
  • 62
    • 0027976913 scopus 로고
    • The retinoblastoma gene product is a cell cycle-dependent, nuclear matrix-associated protein
    • Mancini, M. A., Shan, B., Nickerson, J. A., Penman, S. and Lee, W. H. (1994). The retinoblastoma gene product is a cell cycle-dependent, nuclear matrix-associated protein. Proc. Natl. Acad. Sci. USA 91, 418-422.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 418-422
    • Mancini, M.A.1    Shan, B.2    Nickerson, J.A.3    Penman, S.4    Lee, W.H.5
  • 63
    • 0027104001 scopus 로고
    • Dynamics of three-dimensional replication patterns during the S-phase, analysed by double labelling of DNA and confocal microscopy
    • Manders, E. M., Stap, J., Brakenhoff, G. J., van Driel, R. and Aten, J. A. (1992). Dynamics of three-dimensional replication patterns during the S-phase, analysed by double labelling of DNA and confocal microscopy. J. Cell Sci. 103, 857-862.
    • (1992) J. Cell Sci. , vol.103 , pp. 857-862
    • Manders, E.M.1    Stap, J.2    Brakenhoff, G.J.3    van Driel, R.4    Aten, J.A.5
  • 64
    • 0033535323 scopus 로고    scopus 로고
    • Direct imaging of DNA in living cells reveals the dynamics of chromosome formation
    • Manders, E. M., Kimura, H. and Cook, P. R. (1999). Direct imaging of DNA in living cells reveals the dynamics of chromosome formation. J. Cell Biol. 144, 813-821.
    • (1999) J. Cell Biol. , vol.144 , pp. 813-821
    • Manders, E.M.1    Kimura, H.2    Cook, P.R.3
  • 65
    • 0021265953 scopus 로고
    • Active nucleolus organizers are precisely positioned in adult central nervous system cells but not in neuroectodermal tumor cells
    • Manuelidis, L. (1984). Active nucleolus organizers are precisely positioned in adult central nervous system cells but not in neuroectodermal tumor cells. J. Neuropathol. Exp. Neurol. 43, 225-241.
    • (1984) J. Neuropathol. Exp. Neurol. , vol.43 , pp. 225-241
    • Manuelidis, L.1
  • 66
    • 0032511093 scopus 로고    scopus 로고
    • Nucleosome assembly activity and intracellular localization of human CAF-1 changes during the cell division cycle
    • Marheineke, K. and Krude, T. (1998). Nucleosome assembly activity and intracellular localization of human CAF-1 changes during the cell division cycle. J. Biol. Chem. 273, 15279-15286.
    • (1998) J. Biol. Chem. , vol.273 , pp. 15279-15286
    • Marheineke, K.1    Krude, T.2
  • 67
    • 0032143446 scopus 로고    scopus 로고
    • Nuclear domain 10, the site of DNA virus transcription and replication
    • Maul, G. G. (1998). Nuclear domain 10, the site of DNA virus transcription and replication. Bioessays 20, 660-667.
    • (1998) Bioessays , vol.20 , pp. 660-667
    • Maul, G.G.1
  • 68
    • 0027607455 scopus 로고
    • Improved techniques for immortalizing animal cells
    • McLean, J. S. (1993). Improved techniques for immortalizing animal cells. Trends Biotechnol. 11, 232-238.
    • (1993) Trends Biotechnol. , vol.11 , pp. 232-238
    • McLean, J.S.1
  • 69
    • 0020045372 scopus 로고
    • An electron microscope study of chromosomal DNA replication in different eukaryotic systems
    • Micheli, G., Baldari, C. T., Carri, M. T., di Cello, G. and Buongiorno-Nardelli, M. (1982). An electron microscope study of chromosomal DNA replication in different eukaryotic systems. Exp. Cell Res. 137, 127-140.
    • (1982) Exp. Cell Res. , vol.137 , pp. 127-140
    • Micheli, G.1    Baldari, C.T.2    Carri, M.T.3    di Cello, G.4    Buongiorno-Nardelli, M.5
  • 70
    • 0024851254 scopus 로고
    • Cell cycle-dependent regulation of phosphorylation of the human retinoblastoma gene product
    • Mihara, K., Cao, X. R., Yen, A., Chandler, S., Driscoll, B., Murphree, A. L., T'Ang, A. and Fung, Y. K. (1989). Cell cycle-dependent regulation of phosphorylation of the human retinoblastoma gene product. Science 246, 1300-1303.
    • (1989) Science , vol.246 , pp. 1300-1303
    • Mihara, K.1    Cao, X.R.2    Yen, A.3    Chandler, S.4    Driscoll, B.5    Murphree, A.L.6    T'Ang, A.7    Fung, Y.K.8
  • 71
    • 0019792365 scopus 로고
    • Methotrexate-resistant Chinese hamster ovary cells have amplified a 135-kilobase-pair region that includes the dihydrofolate reductase gene
    • Milbrandt, J. D., Heintz, N. H., White, W. C., Rothman, S. M. and Hamlin, J. L. (1981). Methotrexate-resistant Chinese hamster ovary cells have amplified a 135-kilobase-pair region that includes the dihydrofolate reductase gene. Proc. Natl. Acad. Sci. USA 78, 6043-6047.
    • (1981) Proc. Natl. Acad. Sci. USA , vol.78 , pp. 6043-6047
    • Milbrandt, J.D.1    Heintz, N.H.2    White, W.C.3    Rothman, S.M.4    Hamlin, J.L.5
  • 72
    • 0033791228 scopus 로고    scopus 로고
    • Detection of S-phase cells in tissue sections by in situ DNA replication
    • Mills, A. D., Coleman, N., Morris, L. S. and Laskey, R. A. (2000). Detection of S-phase cells in tissue sections by in situ DNA replication. Nat. Cell Biol. 2, 244-245.
    • (2000) Nat. Cell Biol. , vol.2 , pp. 244-245
    • Mills, A.D.1    Coleman, N.2    Morris, L.S.3    Laskey, R.A.4
  • 73
    • 0025810049 scopus 로고
    • G1/S phosphorylation of the retinoblastoma protein is associated with an altered affinity for the nuclear compartment
    • Mittnacht, S. and Weinberg, R. A. (1991). G1/S phosphorylation of the retinoblastoma protein is associated with an altered affinity for the nuclear compartment. Cell 65, 381-393.
    • (1991) Cell , vol.65 , pp. 381-393
    • Mittnacht, S.1    Weinberg, R.A.2
  • 74
    • 0029978325 scopus 로고    scopus 로고
    • E21F-4 switches from p 130 to p107 and pRB in response to cell cycle reentry
    • Moberg, K., Starz, M. A. and Lees, J. A. (1996). E21F-4 switches from p 130 to p107 and pRB in response to cell cycle reentry. Mol. Cell. Biol. 16, 1436-1449.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 1436-1449
    • Moberg, K.1    Starz, M.A.2    Lees, J.A.3
  • 76
    • 0039227088 scopus 로고    scopus 로고
    • Induction of S-phase entry by E2F transcription factors depends on their nuclear localization
    • Muller, H., Moroni, M. C., Vigo, E., Petersen, B. O., Bartek, J. and Helin, K. (1997). Induction of S-phase entry by E2F transcription factors depends on their nuclear localization. Mol. Cell. Biol. 17, 5508-5520.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 5508-5520
    • Muller, H.1    Moroni, M.C.2    Vigo, E.3    Petersen, B.O.4    Bartek, J.5    Helin, K.6
  • 77
    • 0033212963 scopus 로고    scopus 로고
    • Heterochromatin dynamics in mouse cells: Interaction between chromatin assembly factor 1 and HP1 proteins
    • Murzina, N., Verreault, A., Lane, E. and Stillman, B. (1999). Heterochromatin dynamics in mouse cells: interaction between chromatin assembly factor 1 and HP1 proteins. Mol. Cell 4, 529-540.
    • (1999) Mol. Cell , vol.4 , pp. 529-540
    • Murzina, N.1    Verreault, A.2    Lane, E.3    Stillman, B.4
  • 78
    • 0022504648 scopus 로고
    • Structural organization of replicon domains during DNA synthetic phase in the mammalian nucleus
    • Nakamura, H., Morita, T. and Sato, C. (1986). Structural organization of replicon domains during DNA synthetic phase in the mammalian nucleus. Exp. Cell Res. 165, 291-297.
    • (1986) Exp. Cell Res. , vol.165 , pp. 291-297
    • Nakamura, H.1    Morita, T.2    Sato, C.3
  • 79
    • 0024526184 scopus 로고
    • Mapping replicational sites in the eucaryotic cell nucleus
    • Nakayasu, H. and Berezney, R. (1989). Mapping replicational sites in the eucaryotic cell nucleus. J. Cell Biol. 108, 1-11.
    • (1989) J. Cell Biol. , vol.108 , pp. 1-11
    • Nakayasu, H.1    Berezney, R.2
  • 80
    • 0035063183 scopus 로고    scopus 로고
    • The Rb/E2F pathway and cancer
    • Nevins, J. R. (2001). The Rb/E2F pathway and cancer. Hum. Mol. Genet. 10, 699-703.
    • (2001) Hum. Mol. Genet. , vol.10 , pp. 699-703
    • Nevins, J.R.1
  • 81
    • 0031961995 scopus 로고    scopus 로고
    • Effects of p21(Cip1/Waf1) at both the G1/S and the G2/M cell cycle transitions: PRb is a critical determinant in blocking DNA replication and in preventing endoreduplication
    • Niculescu, A. B., 3rd, Chen, X., Smeets, M., Hengst, L., Prives, C. and Reed, S. I. (1998). Effects of p21(Cip1/Waf1) at both the G1/S and the G2/M cell cycle transitions: pRb is a critical determinant in blocking DNA replication and in preventing endoreduplication. Mol. Cell. Biol. 18, 629-643.
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 629-643
    • Niculescu A.B. III1    Chen, X.2    Smeets, M.3    Hengst, L.4    Prives, C.5    Reed, S.I.6
  • 82
    • 0026596327 scopus 로고
    • Dynamic organization of DNA replication in mammalian cell nuclei: Spatially and temporally defined replication of chromosome-specific alpha-satellite DNA sequences
    • O'Keefe, R. T., Henderson, S. C. and Spector, D. L. (1992). Dynamic organization of DNA replication in mammalian cell nuclei: spatially and temporally defined replication of chromosome-specific alpha-satellite DNA sequences. J. Cell Biol. 116, 1095-1110.
    • (1992) J. Cell Biol. , vol.116 , pp. 1095-1110
    • O'Keefe, R.T.1    Henderson, S.C.2    Spector, D.L.3
  • 83
    • 0028673957 scopus 로고
    • Direct visualization of DNA replication sites in living cells by microinjection of fluorescein-conjugated dUTPs
    • Pepperkok, R. and Ansorge, W. (1995). Direct visualization of DNA replication sites in living cells by microinjection of fluorescein-conjugated dUTPs. Methods Mol. Cell. Biol. 5, 112-117.
    • (1995) Methods Mol. Cell. Biol. , vol.5 , pp. 112-117
    • Pepperkok, R.1    Ansorge, W.2
  • 84
    • 0024384664 scopus 로고
    • Cancer as a disease of DNA organization and dynamic cell structure
    • Pienta, K. J., Partin, A. W. and Coffey, D. S. (1989). Cancer as a disease of DNA organization and dynamic cell structure. Cancer Res. 49, 2525-2532.
    • (1989) Cancer Res. , vol.49 , pp. 2525-2532
    • Pienta, K.J.1    Partin, A.W.2    Coffey, D.S.3
  • 85
    • 0037083752 scopus 로고    scopus 로고
    • The retinoblastoma gene product interacts with maintenance human DNA (cytosine-5) methyltransferase and modulates its activity
    • Pradhan, S. and Kim, G. D. (2002). The retinoblastoma gene product interacts with maintenance human DNA (cytosine-5) methyltransferase and modulates its activity. EMBO J. 21, 779-788.
    • (2002) EMBO J. , vol.21 , pp. 779-788
    • Pradhan, S.1    Kim, G.D.2
  • 86
    • 0033919595 scopus 로고    scopus 로고
    • DNMT1 forms a complex with Rb, E2F1 and HDAC1 and represses transcription from E2F-responsive promoters
    • Robertson, K. D., Ait-Si-Ali, S., Yokochi, T., Wade, P, A., Jones, P. L. and Wolffe, A. P. (2000). DNMT1 forms a complex with Rb, E2F1 and HDAC1 and represses transcription from E2F-responsive promoters. Nat. Genet. 25, 338-342.
    • (2000) Nat. Genet. , vol.25 , pp. 338-342
    • Robertson, K.D.1    Ait-Si-Ali, S.2    Yokochi, T.3    Wade, PA.4    Jones, P.L.5    Wolffe, A.P.6
  • 87
    • 0033569961 scopus 로고    scopus 로고
    • The replication factory targeting sequence/PCNA-binding site is required in G(1) to control the phosphorylation status of DNA ligase I
    • Rossi, R., Villa, A., Negri, C., Scovassi, I., Ciarrocchi, G., Biamonti, G. and Montecucco, A. (1999). The replication factory targeting sequence/PCNA-binding site is required in G(1) to control the phosphorylation status of DNA ligase I. EMBO J. 18, 5745-5754.
    • (1999) EMBO J. , vol.18 , pp. 5745-5754
    • Rossi, R.1    Villa, A.2    Negri, C.3    Scovassi, I.4    Ciarrocchi, G.5    Biamonti, G.6    Montecucco, A.7
  • 88
    • 0033945861 scopus 로고    scopus 로고
    • DNMT1 binds HDAC2 and a new co-repressor, DMAP1, to form a complex at replication foci
    • Rountree, M. R., Bachman, K. E. and Baylin, S. B. (2000). DNMT1 binds HDAC2 and a new co-repressor, DMAP1, to form a complex at replication foci. Nat. Genet. 25, 269-277.
    • (2000) Nat. Genet. , vol.25 , pp. 269-277
    • Rountree, M.R.1    Bachman, K.E.2    Baylin, S.B.3
  • 89
    • 0034996508 scopus 로고    scopus 로고
    • Retinoblastoma tumor suppressor protein signals through inhibition of cyclin-dependent kinase 2 activity to disrupt PCNA function in S phase
    • Sever-Chroneos, Z., Angus, S. P., Fribourg, A. F., Wan, H., Todorov, I., Knudsen, K. E. and Knudsen, E. S. (2001). Retinoblastoma tumor suppressor protein signals through inhibition of cyclin-dependent kinase 2 activity to disrupt PCNA function in S phase. Mol. Cell. Biol. 21, 4032-4045.
    • (2001) Mol. Cell. Biol. , vol.21 , pp. 4032-4045
    • Sever-Chroneos, Z.1    Angus, S.P.2    Fribourg, A.F.3    Wan, H.4    Todorov, I.5    Knudsen, K.E.6    Knudsen, E.S.7
  • 90
    • 0033582544 scopus 로고    scopus 로고
    • Replication-dependent marking of DNA by PCNA facilitates CAF-1-coupled inheritance of chromatin
    • Shibahara, K. and Stillman, B. (1999). Replication-dependent marking of DNA by PCNA facilitates CAF-1-coupled inheritance of chromatin. Cell 96, 575-585.
    • (1999) Cell , vol.96 , pp. 575-585
    • Shibahara, K.1    Stillman, B.2
  • 91
    • 0035089657 scopus 로고    scopus 로고
    • Targeting of PCNA to sites of DNA replication in the mammalian cell nucleus
    • Somanathan, S., Suchyna, T. M., Siegel, A. J. and Berezney, R. (2001). Targeting of PCNA to sites of DNA replication in the mammalian cell nucleus. J. Cell Biochem. 81, 56-67.
    • (2001) J. Cell Biochem. , vol.81 , pp. 56-67
    • Somanathan, S.1    Suchyna, T.M.2    Siegel, A.J.3    Berezney, R.4
  • 92
    • 0017236923 scopus 로고
    • Localization of DNA replicator sites near the nuclear membrane in plant cells
    • Sparvoli, E., Galli, M. G., Mosca, A. and Paris, G. (1976). Localization of DNA replicator sites near the nuclear membrane in plant cells. Exp. Cell Res. 97, 74-82.
    • (1976) Exp. Cell Res. , vol.97 , pp. 74-82
    • Sparvoli, E.1    Galli, M.G.2    Mosca, A.3    Paris, G.4
  • 93
    • 0030589482 scopus 로고    scopus 로고
    • Nuclear organization and gene expression
    • Spector, D. L. (1996). Nuclear organization and gene expression. Exp. Cell Res. 229, 189-197.
    • (1996) Exp. Cell Res. , vol.229 , pp. 189-197
    • Spector, D.L.1
  • 94
    • 0027056909 scopus 로고
    • Differences in snRNP localization between transformed and nontransformed cells
    • Spector, D. L., Lark, G. and Huang, S. (1992). Differences in snRNP localization between transformed and nontransformed cells. Mol. Biol. Cell 3, 555-569.
    • (1992) Mol. Biol. Cell , vol.3 , pp. 555-569
    • Spector, D.L.1    Lark, G.2    Huang, S.3
  • 95
    • 0031945518 scopus 로고    scopus 로고
    • Negative regulation of DNA replication by the retinoblastoma protein is mediated by its association with MCM7
    • Sterner, J. M., Dew-Knight, S., Musahl, C., Kornbluth, S. and Horowitz, J. M. (1998). Negative regulation of DNA replication by the retinoblastoma protein is mediated by its association with MCM7. Mol. Cell. Biol. 18, 2748-2757.
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 2748-2757
    • Sterner, J.M.1    Dew-Knight, S.2    Musahl, C.3    Kornbluth, S.4    Horowitz, J.M.5
  • 98
    • 0036468915 scopus 로고    scopus 로고
    • High mobility group protein I(Y): A candidate architectural protein for chromosomal rearrangements in prostate cancer cells
    • Takaha, N., Hawkins, A. L., Griffin, C. A., Isaacs, W. B. and Coffey, D. S. (2002). High mobility group protein I(Y): a candidate architectural protein for chromosomal rearrangements in prostate cancer cells. Cancer Res. 62, 647-651.
    • (2002) Cancer Res. , vol.62 , pp. 647-651
    • Takaha, N.1    Hawkins, A.L.2    Griffin, C.A.3    Isaacs, W.B.4    Coffey, D.S.5
  • 99
    • 0017656858 scopus 로고
    • Increase in DNA replication sites in cells held at the beginning of S phase
    • Taylor, J. H. (1977). Increase in DNA replication sites in cells held at the beginning of S phase. Chromosoma 62, 291-300.
    • (1977) Chromosoma , vol.62 , pp. 291-300
    • Taylor, J.H.1
  • 100
    • 0029615477 scopus 로고
    • Fibroblasts transformed by combinations of ras, myc and mutant p53 exhibit increased phosphorylation of histone H1 that is independent of metastatic potential
    • Taylor, W. R., Chadee, D. N., Allis, C. D., Wright, J. A. and Davie, J. R. (1995). Fibroblasts transformed by combinations of ras, myc and mutant p53 exhibit increased phosphorylation of histone H1 that is independent of metastatic potential. FEBS Lett. 377, 51-53.
    • (1995) FEBS Lett. , vol.377 , pp. 51-53
    • Taylor, W.R.1    Chadee, D.N.2    Allis, C.D.3    Wright, J.A.4    Davie, J.R.5
  • 101
    • 0029074364 scopus 로고
    • BM28, a human member of the MCM2-3-5 family, is displaced from chromatin during DNA replication
    • Todorov, I. T., Attaran, A. and Kearsey, S. E. (1995). BM28, a human member of the MCM2-3-5 family, is displaced from chromatin during DNA replication. J. Cell Biol. 129, 1433-1445.
    • (1995) J. Cell Biol. , vol.129 , pp. 1433-1445
    • Todorov, I.T.1    Attaran, A.2    Kearsey, S.E.3
  • 102
    • 0024518254 scopus 로고
    • Subdivision of S-phase by analysis of nuclear 5-bromodeoxyuridine staining patterns
    • van Dierendonck, J. H., Keyzer, R., van de Velde, C. J. and Cornelisse, C. J. (1989). Subdivision of S-phase by analysis of nuclear 5-bromodeoxyuridine staining patterns. Cytometry 10, 143-150.
    • (1989) Cytometry , vol.10 , pp. 143-150
    • van Dierendonck, J.H.1    Keyzer, R.2    van de Velde, C.J.3    Cornelisse, C.J.4
  • 103
    • 0028948230 scopus 로고
    • The levels of ubiquitinated histone H2A are highly upregulated in transformed human cells: Partial colocalization of uH2A clusters and PCNA/cyclin foci in a fraction of cells in S-phase
    • Vassilev, A. P., Rasmussen, H. H., Christensen, E. I., Nielsen, S. and Celis, J. E. (1995). The levels of ubiquitinated histone H2A are highly upregulated in transformed human cells: partial colocalization of uH2A clusters and PCNA/cyclin foci in a fraction of cells in S-phase. J. Cell Sci. 108, 1205-1215.
    • (1995) J. Cell Sci. , vol.108 , pp. 1205-1215
    • Vassilev, A.P.1    Rasmussen, H.H.2    Christensen, E.I.3    Nielsen, S.4    Celis, J.E.5
  • 104
    • 0033538831 scopus 로고    scopus 로고
    • Three-dimensional visualization of transcription sites and their association with splicing factor-rich nuclear speckles
    • Wei, X., Somanathan, S., Samarabandu, J. and Berezney, R. (1999). Three-dimensional visualization of transcription sites and their association with splicing factor-rich nuclear speckles. J. Cell Biol. 146, 543-558.
    • (1999) J. Cell Biol. , vol.146 , pp. 543-558
    • Wei, X.1    Somanathan, S.2    Samarabandu, J.3    Berezney, R.4
  • 105
    • 0033857983 scopus 로고    scopus 로고
    • Target gene specificity of E2F and pocket protein family members in living cells
    • Wells, J., Boyd, K. E., Fry, C. J., Bartley, S. M. and Farnham, P. J. (2000). Target gene specificity of E2F and pocket protein family members in living cells. Mol. Cell. Biol. 20, 5797-5807.
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 5797-5807
    • Wells, J.1    Boyd, K.E.2    Fry, C.J.3    Bartley, S.M.4    Farnham, P.J.5
  • 106
    • 0026062090 scopus 로고
    • Localization of p53, retinoblastoma and host replication proteins at sites of viral replication in herpes-infected cells
    • Wilcock, D. and Lane, D. P. (1991). Localization of p53, retinoblastoma and host replication proteins at sites of viral replication in herpes-infected cells. Nature 349, 429-431.
    • (1991) Nature , vol.349 , pp. 429-431
    • Wilcock, D.1    Lane, D.P.2
  • 107
    • 0014896995 scopus 로고
    • Distribution of DNA replicator sites in mammalian nuclei after different methods of cell synchronization
    • Williams, C. A. and Ockey, C. H. (1970). Distribution of DNA replicator sites in mammalian nuclei after different methods of cell synchronization. Exp. Cell Res. 63, 365-372.
    • (1970) Exp. Cell Res. , vol.63 , pp. 365-372
    • Williams, C.A.1    Ockey, C.H.2
  • 108
    • 0035831041 scopus 로고    scopus 로고
    • Lamins and disease: Insights into nuclear infrastructure
    • Wilson, K. L., Zastrow, M. S. and Lee, K. K. (2001). Lamins and disease: insights into nuclear infrastructure. Cell 104, 647-650.
    • (2001) Cell , vol.104 , pp. 647-650
    • Wilson, K.L.1    Zastrow, M.S.2    Lee, K.K.3
  • 109
    • 0032536775 scopus 로고    scopus 로고
    • Transformation abrogates an early G1-phase arrest point required for specification of the Chinese hamster DHFR replication origin
    • Wu, J. R., Keezer, S. M. and Gilbert, D. M. (1998). Transformation abrogates an early G1-phase arrest point required for specification of the Chinese hamster DHFR replication origin. EMBO J. 17, 1810-1818.
    • (1998) EMBO J. , vol.17 , pp. 1810-1818
    • Wu, J.R.1    Keezer, S.M.2    Gilbert, D.M.3
  • 110
    • 0031586028 scopus 로고    scopus 로고
    • Reassembly of functional nucleoli following in situ unraveling by low-ionic-strength treatment of cultured mammalian cells
    • Zatsepina, O. V., Dudnic, O. A., Chentsov, Y. S., Thiry, M., Spring, H. and Trendelenburg, M. F. (1997). Reassembly of functional nucleoli following in situ unraveling by low-ionic-strength treatment of cultured mammalian cells. Exp. Cell Res. 233, 155-168.
    • (1997) Exp. Cell Res. , vol.233 , pp. 155-168
    • Zatsepina, O.V.1    Dudnic, O.A.2    Chentsov, Y.S.3    Thiry, M.4    Spring, H.5    Trendelenburg, M.F.6
  • 111
    • 0030909002 scopus 로고    scopus 로고
    • Dynamic relocation of transcription and splicing factors dependent upon transcriptional activity
    • Zeng, C., Kim, E., Warren, S. L. and Berget, S. M. (1997). Dynamic relocation of transcription and splicing factors dependent upon transcriptional activity. EMBO J. 16, 1401-1412.
    • (1997) EMBO J. , vol.16 , pp. 1401-1412
    • Zeng, C.1    Kim, E.2    Warren, S.L.3    Berget, S.M.4
  • 112
    • 0035835815 scopus 로고    scopus 로고
    • The retinoblastoma gene: A prototypic and multifunctional tumor suppressor
    • Zheng, L. and Lee, W. H. (2001). The retinoblastoma gene: a prototypic and multifunctional tumor suppressor. Exp. Cell Res. 264, 2-18.
    • (2001) Exp. Cell Res. , vol.264 , pp. 2-18
    • Zheng, L.1    Lee, W.H.2


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