-
1
-
-
77953776656
-
Future perspectives in hepatocellular carcinoma
-
Wörns MA and Galle PR: Future perspectives in hepatocellular carcinoma. Dig Liver Dis 3: S302-S309, 2010.
-
(2010)
Dig Liver Dis
, vol.3
-
-
Wörns, M.A.1
Galle, P.R.2
-
2
-
-
67651151325
-
Current management strategy of hepatocellular carcinoma
-
Rampone B, Schiavone B, Martino A, Viviano C and ConfuortoG: Current management strategy of hepatocellular carcinoma. World J Gastroenterol 15: 3210-3216, 2009.
-
(2009)
World J Gastroenterol
, vol.15
, pp. 3210-3216
-
-
Rampone, B.1
Schiavone, B.2
Martino, A.3
Viviano, C.4
Confuorto, G.5
-
3
-
-
34250020201
-
Hepatocellular carcinoma: Epidemiology and molecular carcinogenesis
-
El-Serag HB and Rudolph KL: Hepatocellular carcinoma: epidemiology and molecular carcinogenesis. Gastroenterology 132: 2557-2576, 2007.
-
(2007)
Gastroenterology
, vol.132
, pp. 2557-2576
-
-
El-Serag, H.B.1
Rudolph, K.L.2
-
4
-
-
79951683605
-
Hepatocellular carcinoma: Current management and perspectives for the future
-
Rahbari NN, Mehrabi A, Mollberg NM, Müller SA, KochM, Büchler MW and Weitz J: Hepatocellular carcinoma: current management and perspectives for the future. Ann Surg 253: 453-469, 2011.
-
(2011)
Ann Surg
, vol.253
, pp. 453-469
-
-
Rahbari, N.N.1
Mehrabi, A.2
Mollberg, N.M.3
Müller, S.A.4
Koch, M.5
Büchler, M.W.6
Weitz, J.7
-
5
-
-
14944385553
-
Global cancer statistics, 2002
-
Parkin DM, Bray F, Ferlay J and Pisani P: Global cancer statistics, 2002. CA Cancer J Clin 55: 74-108, 2005.
-
(2005)
CA Cancer J Clin
, vol.55
, pp. 74-108
-
-
Parkin, D.M.1
Bray, F.2
Ferlay, J.3
Pisani, P.4
-
7
-
-
33845883544
-
Embelin, an inhibitor of X chromosome-linked inhibitor-of-apoptosis protein, blocks nuclear factor-kappaB (NF-kappaB) signaling pathway leading to suppression of NF-kappaB-regulated antiapoptotic and metastatic gene products
-
Ahn KS, Sethi G and Aggarwal BB: Embelin, an inhibitor of X chromosome-linked inhibitor-of-apoptosis protein, blocks nuclear factor-kappaB (NF-kappaB) signaling pathway leading to suppression of NF-kappaB-regulated antiapoptotic and metastatic gene products. Mol Pharmacol 71: 209-219, 2007.
-
(2007)
Mol Pharmacol
, vol.71
, pp. 209-219
-
-
Ahn, K.S.1
Sethi, G.2
Aggarwal, B.B.3
-
8
-
-
2342448582
-
Discovery of embelin as a cell-permeable, small-molecular weight inhibitor of XIAP through structure-based computational screening of a traditional herbal medicine three-dimensional structure database
-
Nikolovska-Coleska Z, Xu L, Hu Z, Tomita Y, Li P, Roller PP, Wang R, Fang X, Guo R, Zhang M, Lippman ME, Yang D and Wang S: Discovery of embelin as a cell-permeable, small-molecular weight inhibitor of XIAP through structure-based computational screening of a traditional herbal medicine three-dimensional structure database. J Med Chem 47: 2430-2440, 2004.
-
(2004)
J Med Chem
, vol.47
, pp. 2430-2440
-
-
Nikolovska-Coleska, Z.1
Xu, L.2
Hu, Z.3
Tomita, Y.4
Li, P.5
Roller, P.P.6
Wang, R.7
Fang, X.8
Guo, R.9
Zhang, M.10
Lippman, M.E.11
Yang, D.12
Wang, S.13
-
9
-
-
33947651075
-
Free radical scavenging reactions and antioxidant activity of embelin: Biochemical and pulse radiolytic studies
-
Joshi R, Kamat JP and Mukherjee T: Free radical scavenging reactions and antioxidant activity of embelin: biochemical and pulse radiolytic studies. Chem Biol Interact 167: 125-134, 2007.
-
(2007)
Chem Biol Interact
, vol.167
, pp. 125-134
-
-
Joshi, R.1
Kamat, J.P.2
Mukherjee, T.3
-
10
-
-
33745907263
-
Effects of administration of embelin and curcumin on lipid peroxidation, hepatic glutathione antioxidant defense and hematopoietic system during N-nitrosodiethylamine/phenobarbital-induced hepatocarcinogenesis in Wistar rats
-
Sreepriya M and Bali G: Effects of administration of embelin and curcumin on lipid peroxidation, hepatic glutathione antioxidant defense and hematopoietic system during N-nitrosodiethylamine/phenobarbital-induced hepatocarcinogenesis in Wistar rats. Mol Cell Biochem 284: 49-55, 2006.
-
(2006)
Mol Cell Biochem
, vol.284
, pp. 49-55
-
-
Sreepriya, M.1
Bali, G.2
-
11
-
-
70349120250
-
Effects of embelin on lipid peroxidation and free radical scavenging activity against liver damage in rats
-
May 26, (Epub ahead of print)
-
Singh D, Singh R, Singh P and Gupta RS: Effects of embelin on lipid peroxidation and free radical scavenging activity against liver damage in rats. Basic Clin Pharmacol Toxicol: May 26, 2009 (Epub ahead of print).
-
(2009)
Basic Clin Pharmacol Toxicol
-
-
Singh, D.1
Singh, R.2
Singh, P.3
Gupta, R.S.4
-
12
-
-
38349155799
-
Trastuzumab signaling in ErbB2-overexpressing inflammatory breast cancer correlates with X-linked inhibitor of apoptosis protein expression
-
Aird KM, Ding X, Baras A, Wei J, Morse MA, Clay T, Lyerly HK and Devi GR: Trastuzumab signaling in ErbB2-overexpressing inflammatory breast cancer correlates with X-linked inhibitor of apoptosis protein expression. Mol Cancer Ther 7: 38-47, 2008.
-
(2008)
Mol Cancer Ther
, vol.7
, pp. 38-47
-
-
Aird, K.M.1
Ding, X.2
Baras, A.3
Wei, J.4
Morse, M.A.5
Clay, T.6
Lyerly, H.K.7
Devi, G.R.8
-
13
-
-
66349089835
-
Peroxisome proliferator-activated receptor-gamma contributes to the inhibitory effects of Embelin on colon carcinogenesis
-
Dai Y, Qiao L, Chan KW, Yang M, Ye J, Ma J, Zou B, Gu Q, Wang J, Pang R, Lan HY and Wong BC: Peroxisome proliferator-activated receptor-gamma contributes to the inhibitory effects of Embelin on colon carcinogenesis. Cancer Res 69: 4776-4783, 2009.
-
(2009)
Cancer Res
, vol.69
, pp. 4776-4783
-
-
Dai, Y.1
Qiao, L.2
Chan, K.W.3
Yang, M.4
Ye, J.5
Ma, J.6
Zou, B.7
Gu, Q.8
Wang, J.9
Pang, R.10
Lan, H.Y.11
Wong, B.C.12
-
14
-
-
68149132860
-
Micellar delivery of bicalutamide and embelin for treating prostate cancer
-
Danquah M, Li F, Duke CB III, Miller DD and Mahato RI: Micellar delivery of bicalutamide and embelin for treating prostate cancer. Pharm Res 26: 2081-2092, 2009.
-
(2009)
Pharm Res
, vol.26
, pp. 2081-2092
-
-
Danquah, M.1
Li, F.2
Duke I.I.I, C.B.3
Miller, D.D.4
Mahato, R.I.5
-
15
-
-
34548662911
-
Effect of the XIAP inhibitor Embelin on TRAIL-induced apoptosis of pancreatic cancer cells
-
Mori T, Doi R, Kida A, Nagai K, Kami K, Ito D, Toyoda E, Kawaguchi Y and Uemoto S: Effect of the XIAP inhibitor Embelin on TRAIL-induced apoptosis of pancreatic cancer cells. J Surg Res 142: 281-286, 2007.
-
(2007)
J Surg Res
, vol.142
, pp. 281-286
-
-
Mori, T.1
Doi, R.2
Kida, A.3
Nagai, K.4
Kami, K.5
Ito, D.6
Toyoda, E.7
Kawaguchi, Y.8
Uemoto, S.9
-
16
-
-
80054095560
-
Small molecular anticancer agent SKLB703 induces apoptosis in human hepatocellular carcinoma cells via the mitochondrial apoptotic pathway invitro and inhibits tumor growth invivo
-
Xu YZ, Zheng RL, Zhou Y, Peng F, Lin HJ, Bu Q, Mao YQ, YuLT, Yang L, Yang SY and Zhao YL: Small molecular anticancer agent SKLB703 induces apoptosis in human hepatocellular carcinoma cells via the mitochondrial apoptotic pathway invitro and inhibits tumor growth invivo. Cancer Lett 313: 44-53, 2011.
-
(2011)
Cancer Lett
, vol.313
, pp. 44-53
-
-
Xu, Y.Z.1
Zheng, R.L.2
Zhou, Y.3
Peng, F.4
Lin, H.J.5
Bu, Q.6
Mao, Y.Q.7
Yu, L.T.8
Yang, L.9
Yang, S.Y.10
Zhao, Y.L.11
-
17
-
-
79959213858
-
ZL11n is a novel nitric oxide-releasing derivative of farnesylthiosalicylic acid that induces apoptosis in human hepatoma HepG2 cells via MAPK/mitochondrial pathways
-
Yang L, Ling Y, Zhang Z, Zhao Q, Tang J, Ji H and Zhang Y: ZL11n is a novel nitric oxide-releasing derivative of farnesylthiosalicylic acid that induces apoptosis in human hepatoma HepG2 cells via MAPK/mitochondrial pathways. Biochem Biophys Res Commun 409: 752-757, 2011.
-
(2011)
Biochem Biophys Res Commun
, vol.409
, pp. 752-757
-
-
Yang, L.1
Ling, Y.2
Zhang, Z.3
Zhao, Q.4
Tang, J.5
Ji, H.6
Zhang, Y.7
-
18
-
-
79956339335
-
Curcumin enhanced adriamycin-induced human liver-derived hepatoma G2 cell death through activation of mitochondria-mediated apoptosis and autophagy
-
Qian H, Yang Y and Wang X: Curcumin enhanced adriamycin-induced human liver-derived hepatoma G2 cell death through activation of mitochondria-mediated apoptosis and autophagy. Eur J Pharm Sci 43: 125-131, 2011.
-
(2011)
Eur J Pharm Sci
, vol.43
, pp. 125-131
-
-
Qian, H.1
Yang, Y.2
Wang, X.3
-
19
-
-
79960248825
-
Induction of apoptosis by chelerythrine chloride through mitochondrial pathway and Bcl-2 family proteins in human hepatoma SMMC-7721 cell
-
Zhang ZF, Guo Y, Zhang JB and Wei XH: Induction of apoptosis by chelerythrine chloride through mitochondrial pathway and Bcl-2 family proteins in human hepatoma SMMC-7721 cell. Arch Pharm Res 34: 791-800, 2011.
-
(2011)
Arch Pharm Res
, vol.34
, pp. 791-800
-
-
Zhang, Z.F.1
Guo, Y.2
Zhang, J.B.3
Wei, X.H.4
-
20
-
-
34247155896
-
Regulation of p53-, Bcl-2-and caspase-dependent signaling pathway in xanthorrhizol-induced apoptosis of HepG2 hepatoma cells
-
Handayani T, Sakinah S, Nallappan M and Pihie AH: Regulation of p53-, Bcl-2-and caspase-dependent signaling pathway in xanthorrhizol-induced apoptosis of HepG2 hepatoma cells. Anticancer Res 27: 965-971, 2007.
-
(2007)
Anticancer Res
, vol.27
, pp. 965-971
-
-
Handayani, T.1
Sakinah, S.2
Nallappan, M.3
Pihie, A.H.4
-
21
-
-
0015383455
-
Apoptosis: A basic biological phenomenon with wide-ranging implications in tissue kinetics
-
Kerr JF, Wyllie AH and Currie AR: Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics. Br J Cancer 26: 239-257, 1972.
-
(1972)
Br J Cancer
, vol.26
, pp. 239-257
-
-
Kerr, J.F.1
Wyllie, A.H.2
Currie, A.R.3
-
22
-
-
55949128465
-
Anoikis: A necessary death program for anchorage-dependent cells
-
Chiarugi P and Giannoni E: Anoikis: a necessary death program for anchorage-dependent cells. Biochem Pharmacol 76: 1352-1364, 2008.
-
(2008)
Biochem Pharmacol
, vol.76
, pp. 1352-1364
-
-
Chiarugi, P.1
Giannoni, E.2
-
23
-
-
33947501664
-
Activation of peroxisome proliferator-activated receptor gamma contributes to the survival of T lymphoma cells by affecting cellular metabolism
-
Yang C, Jo SH, Csernus B, Hyjek E, Liu Y, Chadburn A and Wang YL: Activation of peroxisome proliferator-activated receptor gamma contributes to the survival of T lymphoma cells by affecting cellular metabolism. Am J Pathol 170: 722-732, 2007.
-
(2007)
Am J Pathol
, vol.170
, pp. 722-732
-
-
Yang, C.1
Jo, S.H.2
Csernus, B.3
Hyjek, E.4
Liu, Y.5
Chadburn, A.6
Wang, Y.L.7
-
24
-
-
84863790379
-
XIAP inhibition and generation of reactive oxygen species enhances TRAIL sensitivity in inflammatory breast cancer cells
-
June 6, (Epub ahead of print)
-
Allensworth JL, Aird KM, Aldrich AJ, Batinic-Haberle I and Devi GR: XIAP inhibition and generation of reactive oxygen species enhances TRAIL sensitivity in inflammatory breast cancer cells. Mol Cancer Ther: June 6, 2012 (Epub ahead of print).
-
(2012)
Mol Cancer Ther
-
-
Allensworth, J.L.1
Aird, K.M.2
Aldrich, A.J.3
Batinic-Haberle, I.4
Devi, G.R.5
-
25
-
-
84863011324
-
Curcumin induces small cell lung cancer NCI-H446 cell apoptosis via the reactive oxygen species-mediated mitochondrial pathway and not the cell death receptor pathway
-
Yang CL, Ma YG, Xue YX, Liu YY, Xie H and Qiu GR: Curcumin induces small cell lung cancer NCI-H446 cell apoptosis via the reactive oxygen species-mediated mitochondrial pathway and not the cell death receptor pathway. DNA Cell Biol 31: 139-150, 2012.
-
(2012)
DNA Cell Biol
, vol.31
, pp. 139-150
-
-
Yang, C.L.1
Ma, Y.G.2
Xue, Y.X.3
Liu, Y.Y.4
Xie, H.5
Qiu, G.R.6
-
26
-
-
0013198976
-
Mitochondria in cell death: Novel targets for neuroprotection and cardioprotection
-
Mattson MP and Kroemer G: Mitochondria in cell death: novel targets for neuroprotection and cardioprotection. Trends Mol Med 9: 196-205, 2003.
-
(2003)
Trends Mol Med
, vol.9
, pp. 196-205
-
-
Mattson, M.P.1
Kroemer, G.2
-
27
-
-
0242522206
-
Regulation of apoptosis by Bcl-2 family proteins
-
Burlacu A: Regulation of apoptosis by Bcl-2 family proteins. J Cell Mol Med 7: 249-257, 2003.
-
(2003)
J Cell Mol Med
, vol.7
, pp. 249-257
-
-
Burlacu, A.1
-
28
-
-
0034253592
-
BAX-dependent transport of cytochrome c reconstituted in pure liposomes
-
Saito M, Korsmeyer SJ and Schlesinger PH; BAX-dependent transport of cytochrome c reconstituted in pure liposomes. Nat Cell Biol 2: 553-555, 2000.
-
(2000)
Nat Cell Biol
, vol.2
, pp. 553-555
-
-
Saito, M.1
Korsmeyer, S.J.2
Schlesinger, P.H.3
-
29
-
-
1542318100
-
Mitochondrial function in apoptotic neuronal cell death
-
Haeberlein SL: Mitochondrial function in apoptotic neuronal cell death. Neurochem Res 29: 521-530, 2004.
-
(2004)
Neurochem Res
, vol.29
, pp. 521-530
-
-
Haeberlein, S.L.1
-
30
-
-
0029068871
-
Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis
-
Nicholson DW, Ali A, Thornberry NA, Vaillancourt JP, DingCK, Gallant M, Gareau Y, Griffin PR, Labelle M and LazebnikYA: Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis. Nature 376: 37-43, 1995.
-
(1995)
Nature
, vol.376
, pp. 37-43
-
-
Nicholson, D.W.1
Ali, A.2
Thornberry, N.A.3
Vaillancourt, J.P.4
Ding, C.K.5
Gallant, M.6
Gareau, Y.7
Griffin, P.R.8
Labelle, M.9
Lazebnik, Y.A.10
-
31
-
-
8444220527
-
Molecular mechanisms of caspase regulation during apoptosis
-
Riedl SJ and Shi Y: Molecular mechanisms of caspase regulation during apoptosis. Nat Rev Mol Cell Biol 5: 897-907, 2004.
-
(2004)
Nat Rev Mol Cell Biol
, vol.5
, pp. 897-907
-
-
Riedl, S.J.1
Shi, Y.2
|