SB365, Pulsatilla saponin D suppresses the proliferation of human colon cancer cells and induces apoptosis by modulating the AKT/mTOR signalling pathway

Food Chemistry

Volumn 136, Issue 1, 2013, Pages 26-33

  Son, Mi Kwon ^a   Jung, Kyung Hee ^a   Hong, Sang Won ^a   Lee, Hee Seung ^a   Zheng, Hong Mei ^a   Choi, Myung Joo ^a   Seo, Ju Hyeon ^a   Suh, Jun Kyu ^a   Hong, Soon Sun ^a  

^a Inha University School of Medicine   (South Korea)

Author keywords

Angiogenesis; Apoptosis; Colon cancer; Pulsatilla saponin D; SB365

Indexed keywords

ANGIOGENESIS; ANTI-ANGIOGENIC ACTIVITY; ANTI-CANCER MECHANISM; ANTICANCER ACTIVITIES; COLON CANCER; COLON CANCER CELLS; HUMAN COLON CANCER CELLS; IN-VITRO; IN-VIVO; NATURAL PRODUCTS; SB365; SIGNALLING PATHWAYS; TUMOR GROWTH;

DISEASES; METABOLITES; TUMORS;

CELL DEATH;

FLUOROURACIL; HYPOXIA INDUCIBLE FACTOR 1ALPHA; MAMMALIAN TARGET OF RAPAMYCIN; PROTEIN KINASE B; PULSATILLA KOREANA EXTRACT; SAPONIN DERIVATIVE; SB 365; UNCLASSIFIED DRUG; VASCULOTROPIN;

ANGIOGENESIS; ANIMAL TISSUE; ANTIANGIOGENIC ACTIVITY; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL; CANCER GROWTH; CANCER INHIBITION; CELL PROLIFERATION; COLON CANCER; CONTROLLED STUDY; DRUG EFFICACY; DRUG ISOLATION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; PLANT ROOT; PROTEIN EXPRESSION; PULSATILLA; PULSATILLA KOREANA; SIGNAL TRANSDUCTION; TUMOR GROWTH;

APOPTOSIS; CELL PROLIFERATION; COLONIC NEOPLASMS; DOWN-REGULATION; HUMANS; PLANT EXTRACTS; PROTO-ONCOGENE PROTEINS C-AKT; PULSATILLA; SAPONINS; SIGNAL TRANSDUCTION; TOR SERINE-THREONINE KINASES;

PULSATILLA; PULSATILLA KOREANA;

EID: 84865310512     PISSN: 03088146     EISSN: 18737072     Source Type: Journal    
DOI: 10.1016/j.foodchem.2012.07.096     Document Type: Article

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