Cytotoxic triterpenoid saponins from the rhizomes of anemone taipaiensis

Planta Medica

Volumn 77, Issue 13, 2011, Pages 1550-1554

  Wang, Xiao Yang ^a   Chen, Xiao Li ^a   Tang, Hai Feng ^a   Gao, Hui ^b   Tian, Xiang Rong ^c   Zhang, Ping Hu ^d  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^b 309TH HOSPITAL OF PLA   (China)

^c SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

^d CHINA PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

Anemone taipaiensis; cytotoxicity; Ranunculaceae; saponin; triterpenoid

Indexed keywords

3BETA O [ALPHA LEVO RHAMNOPYRANOSYL(1-2)[BETA DEXTRO GLUCOPYRANOSYL(1-4)]ALPHA LEVO ARABINOPYRANOSYL]OLEANOLIC ACID; 3BETA O [BETA DEXTRO XYLOPYRANOSYL(1-3)ALPHA LEVO RHAMNOPYRANOSYL(1-2)[BETA DEXTRO GLUCOPYRANOSYL (1-4)GLUCOPYRANOSYL(1-4)]ALPHA LEVO ARABINOPYRANOSYL]OLEANOLIC ACID; 3BETA O [BETA DEXTRO XYLOPYRANOSYL(1-3)ALPHA LEVO RHAMNOPYRANOSYL(1-2)[BETA DEXTRO GLUCOPYRANOSYL(1-4)]ALPHA LEVO ARABINOPYRANOSYL]HEDERAGENIN; 3BETA O [BETA DEXTRO XYLOPYRANOSYL(1-3)ALPHA LEVO RHAMNOPYRANOSYL(1-2)ALPHA LEVO ARABINOPYRANOSYL]OLEANOLIC ACID; 3BETA O [BETA DEXTRO XYLOPYRANOSYL(1-3)ALPHA LEVO RHAMNOPYRANOSYL(1-2)ALPHA LEVO ARABINOPYRANOSYL]OLEANOLIC ACID 28 O BETA DEXTRO GLUCOPYRANOSIDE; ANTINEOPLASTIC AGENT; CERNUOSIDE C; PLANT EXTRACT; PULSATILLA SAPONIN D; SAPINDOSIDE B; SAPONIN; SAPONIN DERIVATIVE; TRITERPENOID; UNCLASSIFIED DRUG;

ANEMONE; ANEMONE TAIPAIENSIS; ARTICLE; CELL STRAIN HEPG2; CELL STRAIN HL 60; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG ISOLATION; HUMAN; HUMAN CELL; LEUKEMIA CELL; LIVER CELL CARCINOMA; NONHUMAN; RHIZOME; SPECTROSCOPY;

ANEMONE; ANTINEOPLASTIC AGENTS, PHYTOGENIC; CELL LINE, TUMOR; CELL SURVIVAL; HUMANS; MOLECULAR STRUCTURE; OLEANOLIC ACID; PLANT EXTRACTS; RHIZOME; SAPONINS;

ANEMONE; RANUNCULACEAE;

EID: 80052398215     PISSN: 00320943     EISSN: 14390221     Source Type: Journal    
DOI: 10.1055/s-0030-1270821     Document Type: Article

References (23)

1. Wang M K., Wu F E., Chen Y Z. Triterpenoid saponins from Anemone hupehensis. Phytochemistry 1997 44 333-335
2. Ye W C., Zhang Q W., Pan G S., Zhao S X., Che C T. Two unusual oleanane saponins from Anemone anhuiensis. Planta Med 2001 67 590-592
3. Mimaki Y, Watanabe K, Matsuo Y, Sakagami H. Triterpene glycosides from the tubers of Anemone coronaria. Chem Pharm Bull 2009 57 724-729
4. Chen X, Lu J C., He W F., Chi H D., Yamashita K, Manabe M, Kodama H. Antiperoxidation activity of triterpenoids from rhizome of Anemone raddeana. Fitoterapia 2009 80 105-111
5. Flora of China. Vol. 28 Beijing Science Press 1980 53-54
6. Tang H F., Yi Y H., Li L, Sun P, Zhang S Q., Zhao Y P. Three new asterosaponins from the starfish Culcita novaeguineae and their bioactivity. Planta Med 2005 71 458-463 (Pubitemid 40839781)
7. Lin H, Zhang X, Cheng G, Tang H F., Zhang W, Zhen H N., Cheng J X., Liu B L., Cao W D., Dong W P., Wang P. Apoptosis induced by ardipusilloside III through BAD dephosphorylation and cleavage in human glioblastoma U251MG cells. Apoptosis 2008 13 247-257
8. Tian Y, Tang H F., Qiu F, Wang X J., Chen X L., Wen A D. Triterpenoid saponins from Ardisia pusilla and their cytotoxic activity. Planta Med 2009 75 70-75
9. Tang H F., Yun J, Lin H W., Chen X L., Wang X J., Cheng G. Two new triterpenoid saponins cytotoxic to human glioblastoma U251MG cells from Ardisia pusilla. Chem Biodivers 2009 6 1443-1452
10. Ma N, Tang H F., Qiu F, Lin H W., Tian X R., Yao M N. Polyhydroxysteroidal glycosides from the Starfish Anthenea chinensis. J Nat Prod 2010 73 590-597
11. Joshi B S., Moore K M., Pelletier S W., Puar M S., Pramanik B N. Saponins from Collinsonia canadensis. J Nat Prod 1992 55 1468-1476
12. Ekabo O A., Farnsworth N R., Henderson T O., Mao G H., Mukherjee R. Antifungal and molluscicidal saponins from Serjania salzmanniana. J Nat Prod 1996 59 431-435 (Pubitemid 26139724)
13. De Marino S, Borbone N, Iorizzi M, Esposito G, McClintock J B., Zollo F. Bioactive asterosaponins from the starfish Luidia quinaria and Psilaster cassiope, isolation and structure characterization by two-dimensional NMR spectroscopy. J Nat Prod 2003 66 515-519 (Pubitemid 36531900)
14. Zheng Q, Koike K, Han L K., Okuda H, Nikaido T. New biologically active triterpenoid saponins from Scabiosa tschiliensis. J Nat Prod 2004 67 604-613 (Pubitemid 38533932)
15. Mimaki Y, Kuroda M, Asano T, Sashida Y. Triterpene saponins and lignans from the roots of Pulsatilla chinensis and their cytotoxic activity against HL-60 cells. J Nat Prod 1999 62 1279-1283 (Pubitemid 29463328)
16. Xu T H., Xu Y J., Li H X., Han D, Zhao H F., Xie S X., Li Y, Niu J Z., Si Y S., Xu D M. Two new triterpenoid saponins from Pulsatilla cernua (Thunb.) Bercht. et Opiz. J Asian Nat Prod Res 2007 9 705-711 (Pubitemid 350125724)
17. Nakayama K, Fujino H, Kasai R, Tanaka O, Zhou J. Saponins of pericarps of Chinese Sapindus delavayi (Pyi-shiau-tzu), a source of natural surfactants. Chem Pharm Bull 1986 34 2209-2213 (Pubitemid 16087551)
18. Lavaud C, Crublet M L., Pouny I, Litaudon M, Svenet T. Triterpeniod saponins from the stem bark of Elattostachys apetala. Phytochmistry 2001 57 469-478 (Pubitemid 32448461)
19. Zhang Q W., Ye W C., Che C T., Zhao S X. Triterpene saponins from Pulsatilla cernua. Acta Pharm Sin 2000 35 756-759
20. Shen L, Ye Y H., Wang X T., Zhu H L., Xu C, Song Y C., Li H, Tan R X. Structure and total synthesis of aspernigerin: a novel cytotoxic endophyte metabolite. Chem Eur J 2006 12 4393-4396 (Pubitemid 43829110)
21. Mosmann T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Methods 1983 65 53-63
22. Yokosuka A, Sano T, Hashimoto K, Sakagami H, Mimaki Y. Triterpene glycosides from the whole plant of Anemone hupehensis var. japonica and their cytotoxic activity. Chem Pharm Bull 2009 57 1425-1430
23. Bang S C., Lee J H., Song G Y., Kim D H., Yoon M Y., Ahn B Z. Antitumor activity of Pulsatilla koreana saponins and their structure-activity relationship. Chem Pharm Bull 2005 53 1451-1454