Reprogramming IgH isotype-switched B cells to functional-grade induced pluripotent stem cells

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 34, 2012, Pages 13745-13750

  Wesemann, Duane R ^a,b,c,d   Portuguese, Andrew J ^a,b,c   Magee, Jennifer M ^a,b,c   Gallagher, Michael P ^a,b,c   Zhou, Xiaolong ^a,b,c   Panchakshari, Rohit A ^a,b,c   Alt, Frederick W ^a,b,c  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^d BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; CD40 LIGAND MONOCLONAL ANTIBODY; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN HEAVY CHAIN; IMMUNOGLOBULIN M; INTERLEUKIN 4; METHYLTRANSFERASE INHIBITOR;

ANIMAL CELL; ARTICLE; B LYMPHOCYTE ACTIVATION; CELL CULTURE; CELL MATURATION; CHIMERA; CLASS SWITCH RECOMBINATION; DNA METHYLATION; EXON; GENE CLUSTER; GENE DELETION; GENE EXPRESSION; GENE LOCUS; GENE SWITCHING; GENOME IMPRINTING; MOUSE; NONHUMAN; NUCLEAR REPROGRAMMING; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; SPLEEN;

ANIMALS; B-LYMPHOCYTES; CELL SEPARATION; CYTOLOGICAL TECHNIQUES; DNA-BINDING PROTEINS; FLOW CYTOMETRY; GENETIC TECHNIQUES; GENOME; IMMUNOGLOBULIN CLASS SWITCHING; IMMUNOGLOBULIN HEAVY CHAINS; INDUCED PLURIPOTENT STEM CELLS; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MULTIGENE FAMILY; PLURIPOTENT STEM CELLS;

EID: 84865305089     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1210286109     Document Type: Article

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