Erythropoietin promotes axonal regeneration after optic nerve crush in vivo by inhibition of RhoA/ROCK signaling pathway

Neuropharmacology

Volumn 63, Issue 6, 2012, Pages 1182-1190

  Tan, Haibo ^a   Zhong, Yisheng ^a   Shen, Xi ^a   Cheng, Yu ^a   Jiao, Qin ^a   Deng, Lianfu ^b  

^a SHANGHAI JIAO TONG UNIVERSITY   (China)

^b Shanghai Institute of Traumatology and Orthopedics   (China)

Author keywords

Axon regeneration; Erythropoietin; Optic nerve crush; Retinal ganglion cells; RhoA ROCK pathway

Indexed keywords

4 (1 AMINOETHYL) N (4 PYRIDYL)CYCLOHEXANECARBOXAMIDE; ERYTHROPOIETIN; NEUROMODULIN; RHO KINASE; RHO KINASE 1; RHO KINASE 2; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL SURVIVAL; CONTROLLED STUDY; DOWN REGULATION; ENZYME INACTIVATION; ENZYME INHIBITION; IMMUNOHISTOCHEMISTRY; IN VIVO STUDY; MALE; NERVE FIBER REGENERATION; NONHUMAN; OPTIC NERVE INJURY; PRECIPITATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RETINA GANGLION CELL; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

AMIDES; ANIMALS; AXONS; BLOTTING, WESTERN; CELL SURVIVAL; ENZYME INHIBITORS; ERYTHROPOIETIN; GAP-43 PROTEIN; IMMUNOHISTOCHEMISTRY; MALE; NERVE CRUSH; NERVE REGENERATION; OPTIC NERVE; OPTIC NERVE INJURIES; PYRIDINES; RATS; RATS, SPRAGUE-DAWLEY; RHO-ASSOCIATED KINASES; RHOA GTP-BINDING PROTEIN; SIGNAL TRANSDUCTION; SUPERIOR COLLICULI;

EID: 84865227741     PISSN: 00283908     EISSN: 18737064     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2012.06.037     Document Type: Article

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