A rat model of glaucoma induced by episcleral vein ligation

Experimental Eye Research

Volumn 83, Issue 4, 2006, Pages 758-770

  Yu, Saiyuu ^a   Tanabe, Teruyo ^a   Yoshimura, Nagahisa ^a  

^a KYOTO UNIVERSITY   (Japan)

Author keywords

apoptosis; episcleral vein ligation; glaucoma; M ller cell; rat model; retinal ganglion cell; trophic factor

Indexed keywords

CILIARY NEUROTROPHIC FACTOR; CYCLIN DEPENDENT KINASE INHIBITOR 1B; FIBROBLAST GROWTH FACTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL SURVIVAL; CONTROLLED STUDY; DOWN REGULATION; EYE; FEMALE; GLAUCOMA; INTRAOCULAR PRESSURE; MORPHOLOGY; MUELLER CELL; NEUROPROTECTION; NONHUMAN; OPTIC DISK; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RETINA GANGLION CELL; VEIN LIGATION;

ANIMALS; APOPTOSIS; DISEASE MODELS, ANIMAL; FEMALE; GLAUCOMA; INTRAOCULAR PRESSURE; LIGATION; NERVE GROWTH FACTORS; RATS; RATS, WISTAR; RETINA; RETINAL GANGLION CELLS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SCLERA; VEINS;

EID: 33747877312     PISSN: 00144835     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.exer.2006.03.014     Document Type: Article

References (53)

1. Bayer A.U., Danias J., Brodie S., Maag K.P., Chen B., Shen F., Podos S.M., and Mittag T.W. Electroretinographic abnormalities in a rat glaucoma model with chronic elevated intraocular pressure. Exp. Eye Res. 72 (2001) 667-677
2. Bringmann A., and Reichenbach A. Role of Muller cells in retinal degenerations. Front. Biosci. 6 (2001) E72-E92
3. Casson R.J., Chidlow G., Wood J.P., Vidal-Sanz M., and Osborne N.N. The effect of retinal ganglion cell injury on light-induced photoreceptor degeneration. Invest. Ophthalmol. Vis. Sci. 45 (2004) 685-693
4. Chun M.H., Ju W.K., Kim K.Y., Lee M.Y., Hofmann H.D., Kirsch M., and Oh S.J. Upregulation of ciliary neurotrophic factor in reactive Muller cells in the rat retina following optic nerve transection. Brain Res. 868 (2000) 358-362
5. Connolly S.E., Hjelmeland L.M., and LaVail M.M. Immunohistochemical localization of basic fibroblast growth factor in mature and developing retinas of normal and RCS rats. Curr. Eye Res. 11 (1992) 1005-1017
6. Danias J., Shen F., Kavalarakis M., Chen B., Glodblum D., Lee K., Zamora M.-F., Su Y., Podos M., and Mittag T. Characterization of retinal damage in the episcleral vein cauterization rat glaucoma model. Exp. Eye Res. 82 (2006) 219-228
7. Dyer M.A., and Cepko C.L. p27Kip1 and p57Kip2 regulate proliferation in distinct retinal progenitor cell populations. J. Neurosci. 21 (2001) 4259-4271
8. Fortune B., Bui B.V., Morrison J.C., Johnson E.C., Dong J., Cepurna W.O., Jia L., Barber S., and Cioffi G.A. Selective ganglion cell functional loss in rats with experimental glaucoma. Invest. Ophthalmol. Vis. Sci. 45 (2004) 1854-1862
9. Garcia-Valenzuela E., Shareef S., Walsh J., and Sharma S.C. Programmed cell death of retinal ganglion cells during experimental glaucoma. Exp. Eye Res. 61 (1995) 33-44
10. Glovinsky Y., Quigley H.A., and Dunkelberger G.R. Retinal ganglion cell loss is size dependent in experimental glaucoma. Invest. Ophthalmol. Vis. Sci. 32 (1991) 484-491
11. Grozdanic S.D., Betts D.M., Sakaguchi D.S., Allbaugh R.A., Kwon Y.H., and Kardon R.H. Laser-induced mouse model of chronic ocular hypertension. Invest. Ophthalmol. Vis. Sci. 44 (2003) 4337-4346
12. Grozdanic S.D., Betts D.M., Sakaguchi D.S., Kwon Y.H., Kardon R.H., and Sonea I.M. Temporary elevation of the intraocular pressure by cauterization of vortex and episcleral veins in rats causes functional deficits in the retina and optic nerve. Exp. Eye Res. 77 (2003) 27-33
13. Honjo M., Tanihara H., Kido N., Inatani M., Okazaki K., and Honda Y. Expression of ciliary neurotrophic factor activated by retinal Muller cells in eyes with NMDA- and kainic acid-induced neuronal death. Invest. Ophthalmol. Vis. Sci. 41 (2000) 552-560
14. Ishii Y., Kwong J.M., and Caprioli J. Retinal ganglion cell protection with geranylgeranylacetone, a heat shock protein inducer, in a rat glaucoma model. Invest. Ophthalmol. Vis. Sci. 44 (2003) 1982-1992
15. Ji J.Z., Elyaman W., Yip H.K., Lee V.W., Yick L.W., Hugon J., and So K.F. CNTF promotes survival of retinal ganglion cells after induction of ocular hypertension in rats: the possible involvement of STAT3 pathway. Eur. J. Neurosci. 19 (2004) 265-272
16. Jia L., Cepurna W.O., Johnson E.C., and Morrison J.C. Effect of general anesthetics on IOP in rats with experimental aqueous outflow obstruction. Invest. Ophthalmol. Vis. Sci. 41 (2000) 3415-3419
17. John S.W., Smith R.S., Savinova O.V., Hawes N.L., Chang B., Turnbull D., Davisson M., Roderick T.H., and Heckenlively J.R. Essential iris atrophy, pigment dispersion, and glaucoma in DBA/2J mice. Invest. Ophthalmol. Vis. Sci. 39 (1998) 951-962
18. Johnson J.E., Barde Y.A., Schwab M., and Thoenen H. Brain-derived neurotrophic factor supports the survival of cultured rat retinal ganglion cells. J. Neurosci. 6 (1986) 3031-3038
19. Kanamori A., Nakamura M., Nakanishi Y., Nagai A., Mukuno H., Yamada Y., and Negi A. Akt is activated via insulin/IGF-1 receptor in rat retina with episcleral vein cauterization. Brain Res. 1022 (2004) 195-204
20. Kim I.B., Kim K.Y., Joo C.K., Lee M.Y., Oh S.J., Chung J.W., and Chun M.H. Reaction of Muller cells after increased intraocular pressure in the rat retina. Exp. Brain Res. 121 (1998) 419-424
21. Ko M.L., Hu D.N., Ritch R., and Sharma S.C. The combined effect of brain-derived neurotrophic factor and a free radical scavenger in experimental glaucoma. Invest. Ophthalmol. Vis. Sci. 41 (2000) 2967-2971
22. Krupin T., Feitl M., Roshe R., Lee S., and Becker B. Halothane anesthesia and aqueous humor dynamics in laboratory animals. Invest. Ophthalmol. Vis. Sci. 19 (1980) 518-521
23. Laquis S., Chaudhary P., and Sharma S.C. The patterns of retinal ganglion cell death in hypertensive eyes. Brain Res. 784 (1998) 100-104
24. Levkovitch-Verbin H., Quigley H.A., Martin K.R., Valenta D., Baumrind L.A., and Pease M.E. Translimbal laser photocoagulation to the trabecular meshwork as a model of glaucoma in rats. Invest. Ophthalmol. Vis. Sci. 43 (2002) 402-410
25. Mabuchi F., Lindsey J.D., Aihara M., Mackey M.R., and Weinreb R.N. Optic nerve damage in mice with a targeted type I collagen mutation. Invest. Ophthalmol. Vis. Sci. 45 (2004) 1841-1845
26. Martin K.R., Quigley H.A., Zack D.J., Levkovitch-Verbin H., Kielczewski J., Valenta D., Baumrind L., Pease M.E., Klein R.L., and Hauswirth W.W. Gene therapy with brain-derived neurotrophic factor as a protection: retinal ganglion cells in a rat glaucoma model. Invest. Ophthalmol. Vis. Sci. 44 (2003) 4357-4365
27. Mermoud A., Baerveldt G., Minckler D.S., Lee M.B., and Rao N.A. Intraocular pressure in Lewis rats. Invest. Ophthalmol. Vis. Sci. 35 (1994) 2455-2460
28. Mey J., and Thanos S. Intravitreal injections of neurotrophic factors support the survival of axotomized retinal ganglion cells in adult rats in vivo. Brain Res. 602 (1993) 304-317
29. Mittag T.W., Danias J., Pohorenec G., Yuan H.M., Burakgazi E., Chalmers-Redman R., Podos S.M., and Tatton W.G. Retinal damage after 3 to 4 months of elevated intraocular pressure in a rat glaucoma model. Invest. Ophthalmol. Vis. Sci. 41 (2000) 3451-3459
30. Miyashiro M., Ogata N., Takahashi K., Matsushima M., Yamamoto C., Yamada H., and Uyama M. Expression of basic fibroblast growth factor and its receptor mRNA in retinal tissue following ischemic injury in the rat. Graefes Arch. Clin. Exp. Ophthalmol. 236 (1998) 295-300
31. Miyawaki T., Uemura A., Dezawa M., Yu R.T., Ide C., Nishikawa S., Honda Y., Tanabe Y., and Tanabe T. Tlx, an orphan nuclear receptor, regulates cell numbers and astrocyte development in the developing retina. J. Neurosci. 24 (2004) 8124-8134
32. Morrison J.C., Moore C.G., Deppmeier L.M., Gold B.G., Meshul C.K., and Johnson E.C. A rat model of chronic pressure-induced optic nerve damage. Exp. Eye Res. 64 (1997) 85-96
33. Naskar R., Vorwerk C.K., and Dreyer E.B. Concurrent downregulation of a glutamate transporter and receptor in glaucoma. Invest. Ophthalmol. Vis. Sci. 41 (2000) 1940-1944
34. Naskar R., Wissing M., and Thanos S. Detection of early neuron degeneration and accompanying microglial responses in the retina of a rat model of glaucoma. Invest. Ophthalmol. Vis. Sci. 43 (2002) 2962-2968
35. Pease M.E., McKinnon S.J., Quigley H.A., Kerrigan-Baumrind L.A., and Zack D.J. Obstructed axonal transport of BDNF and its receptor TrkB in experimental glaucoma. Invest. Ophthalmol. Vis. Sci. 41 (2000) 764-774
36. Pederson J.E., and Gaasterland D.E. Laser-induced primate glaucoma. I. Progression of cupping. Arch. Ophthalmol. 102 (1984) 1689-1692
37. Quigley H.A., and Green W.R. The histology of human glaucoma cupping and optic nerve damage: clinicopathologic correlation in 21 eyes. Ophthalmology 86 (1979) 1803-1830
38. Quigley H.A., Dunkelberger G.R., and Green W.R. Chronic human glaucoma causing selectively greater loss of large optic nerve fibers. Ophthalmology 95 (1988) 357-363
39. Quigley H.A., Nickells R.W., Kerrigan L.A., Pease M.E., Thibault D.J., and Zack D.J. Retinal ganglion cell death in experimental glaucoma and after axotomy occurs by apoptosis. Invest. Ophthalmol. Vis. Sci. 36 (1995) 774-786
40. Rudzinski M., Wong T.P., and Saragovi H.U. Changes in retinal expression of neurotrophins and neurotrophin receptors induced by ocular hypertension. J. Neurobiol. 58 (2004) 341-354
41. Sapieha P.S., Peltier M., Rendahl K.G., Manning W.C., and Di Polo A. Fibroblast growth factor-2 gene delivery stimulates axon growth by adult retinal ganglion cells after acute optic nerve injury. Mol. Cell. Neurosci. 24 (2003) 656-672
42. Sarup V., Patil K., and Sharma S.C. Ciliary neurotrophic factor and its receptors are differentially expressed in the optic nerve transected adult rat retina. Brain Res. 1013 (2004) 152-158
43. Sawada A., and Neufeld A.H. Confirmation of the rat model of chronic, moderately elevated intraocular pressure. Exp. Eye Res. 69 (1999) 525-531
44. Shareef S.R., Garcia-Valenzuela E., Salierno A., Walsh J., and Sharma S.C. Chronic ocular hypertension following episcleral venous occlusion in rats. Exp. Eye Res. 61 (1995) 379-382
45. Thanos S., and Naskar R. Correlation between retinal ganglion cell death and chronically developing inherited glaucoma in a new rat mutant. Exp. Eye Res. 79 (2004) 119-129
46. Ueda J., Sawaguchi S., Hanyu T., Yaoeda K., Fukuchi T., Abe H., and Ozawa H. Experimental glaucoma model in the rat induced by laser trabecular photocoagulation after an intracameral injection of India ink. Jpn. J. Ophthalmol. 42 (1998) 337-344
47. Vecino E., Garcia-Grespo D., Garcia M., Martinez-Millan L., Sharma S.C., and Carrascal E. Rat retinal ganglion cells co-express brain derived neurotrophic factor (BDNF) and its receptor TrkB. Vision Res. 42 (2002) 151-157
48. Vidal-Sanz M., Villegas-Perez M.P., Bray G.M., and Aguayo A.J. Persistent retrograde labeling of adult rat retinal ganglion cells with the carbocyanine dye diI. Exp Neurol. 102 (1988) 92-101
49. Von Bartheld C.S. Neurotrophins in the developing and regenerating visual system. Histol. Histopathol. 13 (1998) 437-459
50. Walsh N., Valter K., and Stone J. Cellular and subcellular patterns of expression of bFGF and CNTF in the normal and light stressed adult rat retina. Exp. Eye Res. 72 (2001) 495-501
51. Wang X., Tay S.S., and Ng Y.K. An immunohistochemical study of neuronal and glial cell reactions in retinae of rats with experimental glaucoma. Exp Brain Res. 132 (2000) 476-484
52. Woldemussie E., Wijono M., and Ruiz G. Muller cell response to laser-induced increase in intraocular pressure in rats. Glia 47 (2004) 109-119
53. Wu W.C., Lai C.C., Chen S.L., Sun M.H., Xiao X., Chen T.L., Tsai R.J., Kuo S.W., and Tsao Y.P. GDNF gene therapy attenuates retinal ischemic injuries in rats. Mol. Vis. 10 (2004) 93-102