The ABCG5 ABCG8 sterol transporter opposes the development of fatty liver disease and loss of glycemic control independently of phytosterol accumulation

Journal of Biological Chemistry

Volumn 287, Issue 34, 2012, Pages 28564-28575

  Su, Kai ^a,b   Sabeva, Nadezhda S ^a,b   Liu, Jingjing ^a,b   Wang, Yuhuan ^a,b   Bhatnagar, Saloni ^b   Van Der Westhuyzen, Deneys R ^a,b   Graf, Gregory A ^a,b  

^a UNIVERSITY OF KENTUCKY   (United States)

^b UNIVERSITY OF KENTUCKY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR; ALANINE AMINOTRANSFERASE; DIET-INDUCED OBESITY; EUKARYOTIC TRANSLATION; FATTY LIVER DISEASE; GLYCEMIC CONTROL; INITIATION FACTORS; INSULIN RECEPTOR SUBSTRATE 1; INSULIN RECEPTORS; INSULIN RESISTANCE; KNOCK OUTS; LIPID ACCUMULATIONS; NON-ALCOHOLIC FATTY LIVER DISEASE; PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR; PLANT STEROLS; PROINFLAMMATORY CYTOKINES; PROTEIN KINASE B; SERINE PHOSPHORYLATION; UNFOLDED PROTEIN RESPONSE; WEIGHT GAIN; WILD TYPES;

ALCOHOLS; AMINO ACIDS; CYTOLOGY; GLUCOSE; INSULIN; LIPIDS; MAMMALS; NUTRITION; PHOSPHORYLATION; TRANSCRIPTION FACTORS;

DISEASE CONTROL;

ABCG5 PROTEIN; ABCG8 PROTEIN; ACTIVATING TRANSCRIPTION FACTOR 4; ALANINE AMINOTRANSFERASE; CD36 ANTIGEN; CYTOKINE; FATTY ACID; GLUCOSE; INITIATION FACTOR 2ALPHA; INSULIN RECEPTOR SUBSTRATE 1; MESSENGER RNA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PHYTOSTEROL; PROTEIN KINASE B; REGULATOR PROTEIN; SERINE; STEROL CARRIER PROTEIN; TRIBBLES 3 PROTEIN; UNCLASSIFIED DRUG;

ACTIVATING TRANSCRIPTION FACTOR 4 GENE; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY COMPOSITION; CELL INFILTRATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE COURSE; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; FATTY ACID TRANSPORT; FEMALE; GENE; GENE EXPRESSION REGULATION; GLUCOSE BLOOD LEVEL; GLUCOSE INTOLERANCE; GLYCEMIC CONTROL; INSULIN RESISTANCE; LIPID DIET; LIPID STORAGE; LIVER WEIGHT; MACROPHAGE; MALE; MOUSE; NONALCOHOLIC FATTY LIVER; NONHUMAN; OBESITY; PHENOTYPIC VARIATION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; TRIBBLES 3 GENE; UNFOLDED PROTEIN RESPONSE; WEIGHT GAIN; WILD TYPE;

ALANINE TRANSAMINASE; ANIMALS; ANTIGENS, CD36; ATP-BINDING CASSETTE TRANSPORTERS; DIETARY FATS; EUKARYOTIC INITIATION FACTOR-2; FATTY LIVER; INSULIN RECEPTOR SUBSTRATE PROTEINS; INSULIN RESISTANCE; LIPOPROTEINS; MICE; MICE, KNOCKOUT; MULTIPROTEIN COMPLEXES; ORGAN SIZE; PHOSPHORYLATION; PHYTOSTEROLS; PPAR GAMMA; PROTO-ONCOGENE PROTEINS C-AKT; UNFOLDED PROTEIN RESPONSE;

EID: 84865210263     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.360081     Document Type: Article

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