An essential function of sphingolipids in yeast cell divisionmmi

Molecular Microbiology

Volumn 84, Issue 6, 2012, Pages 1018-1032

  Epstein, Sharon ^a   Castillon, Guillaume A ^a   Qin, Yongmei ^b   Riezman, Howard ^a  

^a UNIVERSITY OF GENEVA   (Switzerland)

^b PEKING UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ACYL COENZYME A; CERAMIDE; CERAMIDE SYNTHASE; SEPTIN; SYNTHETASE; UNCLASSIFIED DRUG;

ARTICLE; AUR1 GENE; CELL GROWTH; CELL SEPARATION; CONTROLLED STUDY; CYTOKINESIS; ENZYME SPECIFICITY; FUNGAL GENE; FUNGAL STRAIN; FUNGUS GROWTH; GENE DELETION; LIPID ANALYSIS; LIPID STORAGE; LIPOGENESIS; NONHUMAN; NUCLEAR DIVISION; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE; WILD TYPE; YEAST CELL;

CELL DIVISION; CERAMIDES; GENE DELETION; GOSSYPIUM; HEXOSYLTRANSFERASES; METABOLIC ENGINEERING; METABOLIC NETWORKS AND PATHWAYS; MICROBIAL VIABILITY; MODELS, BIOLOGICAL; MOLECULAR SEQUENCE DATA; OXIDOREDUCTASES; RECOMBINANT PROTEINS; SACCHAROMYCES CEREVISIAE; SEQUENCE ANALYSIS, DNA;

EUKARYOTA; GOSSYPIUM HIRSUTUM; SACCHAROMYCES CEREVISIAE; SPHINGOIDEA;

EID: 84865195294     PISSN: 0950382X     EISSN: 13652958     Source Type: Journal    
DOI: 10.1111/j.1365-2958.2012.08087.x     Document Type: Article

References (50)

1. Bartke, N., and Hannun, Y.A. (2009) Bioactive sphingolipids: metabolism and function. J Lipid Res 50 (Suppl.): S91-S96.
2. Bose, R., Verheij, M., Haimovitz-Friedman, A., Scotto, K., Fuks, Z., and Kolesnick, R. (1995) Ceramide synthase mediates daunorubicin-induced apoptosis: an alternative mechanism for generating death signals. Cell 82: 405-414.
3. Brandwagt, B.F., Mesbah, L.A., Takken, F.L., Laurent, P.L., Kneppers, T.J., Hille, J., and Nijkamp, H.J. (2000) A longevity assurance gene homolog of tomato mediates resistance to Alternaria alternata f. sp. lycopersici toxins and fumonisin B1. Proc Natl Acad Sci USA 97: 4961-4966.
4. Castillon, G.A.,Watanabe, R., Taylor, M., Schwabe, T.M., and Riezman, H. (2009) Concentration of GPI-anchored proteins upon ER exit in yeast. Traffic 10: 186-200.
5. Cerantola, V., Vionnet, C., Aebischer, O.F., Jenny, T., Knudsen, J., and Conzelmann, A. (2007) Yeast sphingolipids do not need to contain very long chain fatty acids. Biochem J 401: 205-216.
6. Cerantola, V., Guillas, I., Roubaty, C., Vionnet, C., Uldry, D., Knudsen, J., and Conzelmann, A. (2009) Aureobasidin A arrests growth of yeast cells through both ceramide intoxication and deprivation of essential inositolphosphorylceramides. Mol Microbiol 71: 1523-1537.
7. Cid, V.J., Adamikova, L., Sanchez, M., Molina, M., and Nombela, C. (2001) Cell cycle control of septin ring dynamics in the budding yeast. Microbiology 147: 1437-1450.
8. Epstein, S., Kirkpatrick, C.L., Castillon, G.A., Muniz, M., Riezman, I., David, F.P., et al. (2011) Activation of the unfolded protein response pathway causes ceramide accumulation in yeast and INS-1E insulinoma cells. J Lipid Res 53: 412-420.
9. Fath, S., Bauer, A.P., Liss, M., Spriestersbach, A., Maertens, B., Hahn, P., et al. (2011) Multiparameter RNA and codon optimization: a standardized tool to assess and enhance autologous mammalian gene expression. PLoS ONE 6: e17596.
10. Feraru, E., Feraru, M.I., Kleine-Vehn, J., Martiniere, A., Mouille, G., Vanneste, S., et al. (2011) PIN polarity maintenance by the cell wall in Arabidopsis. Curr Biol 21: 338-343.
11. Futerman, A.H., and Riezman, H. (2005) The ins and outs of sphingolipid synthesis. Trends Cell Biol 15: 312-318.
12. Garzotto, M., Haimovitz-Friedman, A., Liao, W.C., White-Jones, M., Huryk, R., Heston, W.D., et al. (1999) Reversal of radiation resistance in LNCaP cells by targeting apoptosis through ceramide synthase. Cancer Res 59: 5194-5201.
13. Guan, X.L., Riezman, I.,Wenk, M.R., and Riezman, H. (2010) Yeast lipid analysis and quantification by mass spectrometry. Methods Enzymol 470: 369-391.
14. Gubern, A., Barcelo-Torns, M., Casas, J., Barneda, D., Masgrau, R., Picatoste, F., et al. (2009) Lipid droplet biogenesis induced by stress involves triacylglycerol synthesis that depends on group VIA phospholipase A2. J Biol Chem 284: 5697-5708.
15. Guillas, I., Kirchman, P.A., Chuard, R., Pfefferli, M., Jiang, J.C., Jazwinski, S.M., and Conzelmann, A. (2001) C26-CoA-dependent ceramide synthesis of Saccharomyces cerevisiae is operated by Lag1p and Lac1p. EMBO J 20: 2655-2665.
16. Guillas, I., Jiang, J.C., Vionnet, C., Roubaty, C., Uldry, D., Chuard, R., et al. (2003) Human homologues of LAG1 reconstitute Acyl-CoA-dependent ceramide synthesis in yeast. J Biol Chem 278: 37083-37091.
17. Hashida-Okado, T., Ogawa, A., Endo, M., Yasumoto, R., Takesako, K., and Kato, I. (1996) AUR1, a novel gene conferring aureobasidin resistance on Saccharomyces cerevisiae: a study of defective morphologies in Aur1pdepleted cells. Mol Gen Genet 251: 236-244.
18. Horvath, A., Sutterlin, C., Manning-Krieg, U., Movva, N.R., and Riezman, H. (1994) Ceramide synthesis enhances transport of GPI-anchored proteins to the Golgi apparatus in yeast. EMBO J 13: 3687-3695.
19. Jennemann, R., Rabionet, M., Gorgas, K., Epstein, S., Dalpke, A., Rothermel, U., et al. (2012) Loss of ceramide synthase 3 causes lethal skin barrier disruption. Hum Mol Genet 21: 586-608.
20. Kanazawa, T., Nakamura, S., Momoi, M., Yamaji, T., Takematsu, H., Yano, H., et al. (2000) Inhibition of cytokinesis by a lipid metabolite, psychosine. J Cell Biol 149: 943-950.
21. Kitatani, K., Idkowiak-Baldys, J., and Hannun, Y.A. (2008) The sphingolipid salvage pathway in ceramide metabolism and signaling. Cell Signal 20: 1010-1018.
22. Koyanagi, S., Kuga, M., Soeda, S., Hosoda, Y., Yokomatsu, T., Takechi, H., et al. (2003) Elevation of de novo ceramide synthesis in tumor masses and the role of microsomal dihydroceramide synthase. Int J Cancer 105: 1-6.
23. Koybasi, S., Senkal, C.E., Sundararaj, K., Spassieva, S., Bielawski, J., Osta, W., et al. (2004) Defects in cell growth regulation by C18:0-ceramide and longevity assurance gene 1 in human head and neck squamous cell carcinomas. J Biol Chem 279: 44311-44319.
24. Kozutsumi, Y., Kanazawa, T., Sun, Y., Yamaji, T., Yamamoto, H., and Takematsu, H. (2002) Sphingolipids involved in the induction of multinuclear cell formation. Biochim Biophys Acta 1582: 138-143.
25. Kraft, C., Deplazes, A., Sohrmann, M., and Peter, M. (2008) Mature ribosomes are selectively degraded upon starvation by an autophagy pathway requiring the Ubp3p/Bre5p ubiquitin protease. Nat Cell Biol 10: 602-610.
26. Krause, S.A., and Gray, J.V. (2002) The protein kinase C pathway is required for viability in quiescence in Saccharomyces cerevisiae. Curr Biol 12: 588-593.
27. Lahiri, S., and Futerman, A.H. (2005) LASS5 is a bona fide dihydroceramide synthase that selectively utilizes palmitoyl-CoA as acyl donor. J Biol Chem 280: 33735-33738.
28. Lahiri, S., Lee, H., Mesicek, J., Fuks, Z., Haimovitz-Friedman, A., Kolesnick, R.N., and Futerman, A.H. (2007) Kinetic characterization of mammalian ceramide synthases: determination of K(m) values towards sphinganine. FEBS Lett 581: 5289-5294.
29. Laviad, E.L., Albee, L., Pankova-Kholmyansky, I., Epstein, S., Park, H., Merrill, A.H., Jr, and Futerman, A.H. (2008) Characterization of ceramide synthase 2: tissue distribution, substrate specificity, and inhibition by sphingosine 1-phosphate. J Biol Chem 283: 5677-5684.
30. Levy, M., and Futerman, A.H. (2010) Mammalian ceramide synthases. IUBMB Life 62: 347-356.
31. Li, H., Junk, P., Huwiler, A., Burkhardt, C., Wallerath, T., Pfeilschifter, J., and Forstermann, U. (2002) Dual effect of ceramide on human endothelial cells: induction of oxidative stress and transcriptional upregulation of endothelial nitric oxide synthase. Circulation 106: 2250-2256.
32. Lopez-Montero, I., Monroy, F., Velez, M., and Devaux, P.F. (2010) Ceramide: from lateral segregation to mechanical stress. Biochim Biophys Acta 1798: 1348-1356.
33. Markham, J.E., Molino, D., Gissot, L., Bellec, Y., Hematy, K., Marion, J., et al. (2011) Sphingolipids containing very-longchain fatty acids define a secretory pathway for specific polar plasma membrane protein targeting in Arabidopsis. Plant Cell 23: 2362-2378.
34. Menuz, V., Howell, K.S., Gentina, S., Epstein, S., Riezman, I., Fornallaz-Mulhauser, M., et al. (2009) Protection of C. elegans from anoxia by HYL-2 ceramide synthase. Science 324: 381-384.
35. Min, J., Mesika, A., Sivaguru, M., Van Veldhoven, P.P., Alexander, H., Futerman, A.H., and Alexander, S. (2007) Dihydro) ceramide synthase 1 regulated sensitivity to cisplatin is associated with the activation of p38 mitogen-activated protein kinase and is abrogated by sphingosine kinase 1. Mol Cancer Res 5: 801-812.
36. Nagiec, M.M., Nagiec, E.E., Baltisberger, J.A., Wells, G.B., Lester, R.L., and Dickson, R.C. (1997) Sphingolipid synthesis as a target for antifungal drugs. Complementation of the inositol phosphorylceramide synthase defect in a mutant strain of Saccharomyces cerevisiae by the AUR1 gene. J Biol Chem 272: 9809-9817.
37. de Nobel, H., and Lipke, P.N. (1994) Is there a role for GPIs in yeast cell-wall assembly? Trends Cell Biol 4: 42-45.
38. Riebeling, C., Allegood, J.C., Wang, E., Merrill, A.H., Jr, and Futerman, A.H. (2003) Two mammalian longevity assurance gene (LAG1) family members, trh1 and trh4, regulate dihydroceramide synthesis using different fatty acyl-CoA donors. J Biol Chem 278: 43452-43459.
39. Riezman, H. (1985) Endocytosis in yeast: several of the yeast secretory mutants are defective in endocytosis. Cell 40: 1001-1009.
40. Roncero, C., and Duran, A. (1985) Effect of Calcofluor white and Congo red on fungal cell wall morphogenesis: in vivo activation of chitin polymerization. J Bacteriol 163: 1180-1185.
41. Schorling, S., Vallee, B., Barz, W.P., Riezman, H., and Oesterhelt, D. (2001) Lag1p and Lac1p are essential for the Acyl-CoA-dependent ceramide synthase reaction in Saccharomyces cerevisiae. Mol Biol Cell 12: 3417-3427.
42. Spassieva, S.D., Markham, J.E., and Hille, J. (2002) The plant disease resistance gene Asc-1 prevents disruption of sphingolipid metabolism during AAL-toxin-induced programmed cell death. Plant J 32: 561-572.
43. Sutterlin, C., Horvath, A., Gerold, P., Schwarz, R.T.,Wang, Y., Dreyfuss, M., and Riezman, H. (1997a) Identification of a species-specific inhibitor of glycosylphosphatidylinositol synthesis. EMBO J 16: 6374-6383.
44. Sutterlin, C., Doering, T.L., Schimmoller, F., Schroder, S., and Riezman, H. (1997b) Specific requirements for the ER to Golgi transport of GPI-anchored proteins in yeast. J Cell Sci 110: 2703-2714.
45. Vallee, B., and Riezman, H. (2005) Lip1p: a novel subunit of acyl-CoA ceramide synthase. EMBO J 24: 730-741.
46. Venkataraman, K., Riebeling, C., Bodennec, J., Riezman, H., Allegood, J.C., Sullards, M.C., et al. (2002) Upstream of growth and differentiation factor 1 (uog1), a mammalian homolog of the yeast longevity assurance gene 1 (LAG1), regulates N-stearoyl-sphinganine (C18-(dihydro)ceramide) synthesis in a fumonisin B1-independent manner in mammalian cells. J Biol Chem 277: 35642-35649.
47. Vida, T.A., and Emr, S.D. (1995) A new vital stain for visual-izing vacuolar membrane dynamics and endocytosis in yeast. J Cell Biol 128: 779-792.
48. White-Gilbertson, S., Mullen, T., Senkal, C., Lu, P., Ogretmen, B., Obeid, L., and Voelkel-Johnson, C. (2009) Ceramide synthase 6 modulates TRAIL sensitivity and nuclear translocation of active caspase-3 in colon cancer cells. Oncogene 28: 1132-1141.
49. Zanolari, B., Sütterlin, C., Stevenson, B.J., and Riezman, H. (2000) Sphingoid base synthesis requirement for endocytosis in Saccharomyces cerevisiae. EMBO J 19: 2824-2833.
50. Zinser, E., and Daum, G. (1995) Isolation and biochemical characterization of organelles from the yeast, Saccharomyces cerevisiae. Yeast 11: 493-536.