Identification of a species-specific inhibitor of glycosylphosphatidylinositol synthesis

EMBO Journal

Volumn 16, Issue 21, 1997, Pages 6374-6383

  Sütterlin, Christine ^a   Horvath, Anton ^a,d   Gerold, Peter ^c   Schwarz, Ralph T ^c   Wang, Ying ^b   Dreyfuss, Michael ^b   Riezman, Howard ^a  

^a UNIVERSITY OF BASEL   (Switzerland)

^b NOVARTIS PHARMA AG   (Switzerland)

^c PHILIPPS UNIVERSITY MARBURG   (Germany)

^d Physics and Informatics   (Slovakia)

Author keywords

GPI; Mannosyltransferase; Protozoa; Yeast

Indexed keywords

ANTIPROTOZOAL AGENT; GLYCOSYLPHOSPHATIDYLINOSITOL; LACTONE; LACTONE DERIVATIVE; MANNOSE; MANNOSYLTRANSFERASE; NATURAL PRODUCT; TERPENOID;

ANIMAL CELL; ARTICLE; CANDIDA ALBICANS; CONTROLLED STUDY; DRUG SCREENING; ENZYME INHIBITION; GOLGI COMPLEX; MAMMAL CELL; MOUSE; NONHUMAN; PHOSPHOLIPID SYNTHESIS; PRIORITY JOURNAL; PROTEIN TRANSPORT; PROTOZOON; SACCHAROMYCES CEREVISIAE; SPECIES DIFFERENCE;

ANIMALS; ANTIPROTOZOAL AGENTS; BIOLOGICAL TRANSPORT; CANDIDA ALBICANS; CARBOHYDRATE SEQUENCE; CELL MEMBRANE; FUNGAL PROTEINS; GLYCOSYLATION; GLYCOSYLPHOSPHATIDYLINOSITOLS; GOLGI APPARATUS; INOSITOL; LACTONES; LYMPHOMA, T-CELL; MANNOSE; MANNOSE-6-PHOSPHATE ISOMERASE; MANNOSYLTRANSFERASES; MEMBRANE GLYCOPROTEINS; MEMBRANE LIPIDS; MEMBRANE PROTEINS; MICE; MOLECULAR SEQUENCE DATA; MOLECULAR STRUCTURE; NEOPLASM PROTEINS; PARAMECIUM; PLASMODIUM FALCIPARUM; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SPECIES SPECIFICITY; SUBSTRATE SPECIFICITY; TERPENES; TOXOPLASMA; TRYPANOSOMA BRUCEI BRUCEI; TUMOR CELLS, CULTURED; YEASTS;

ANIMALIA; CANDIDA ALBICANS; EUKARYOTA; MAMMALIA; PROTOZOA; SACCHAROMYCES CEREVISIAE;

EID: 1642583948     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/16.21.6374     Document Type: Article

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