Comparative expression analysis reveals differences in the regulation of intestinal paraoxonase family members

International Journal of Biochemistry and Cell Biology

Volumn 41, Issue 7, 2009, Pages 1628-1637

  Precourt, Louis Philippe ^a   Seidman, Ernest ^b   Delvin, Edgard ^a   Amre, Devendra ^a   Deslandres, Colette ^a   Dominguez, Michel ^a   Sinnett, Daniel ^a   Levy, Emile ^a  

^a UNIVERSITÉ DE MONTRÉAL   (Canada)

^b MCGILL UNIVERSITY   (Canada)

Author keywords

Caco 2 cells; Inflammation; Peroxidation; PON; Regulation

Indexed keywords

ANTIOXIDANT; ARYLDIALKYLPHOSPHATASE; ARYLDIALKYLPHOSPHATASE 1; ARYLDIALKYLPHOSPHATASE 2; ARYLDIALKYLPHOSPHATASE 3; ASCORBIC ACID; CAFFEIC ACID PHENETHYL ESTER; GAMMA INTERFERON; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; IRON; LIPOPOLYSACCHARIDE; POLYCARBONATE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; ENZYME REGULATION; GENE CLUSTER; GENE EXPRESSION; HUMAN; HUMAN CELL; LIPID PEROXIDATION; OXIDATIVE STRESS; PROTEIN EXPRESSION; WESTERN BLOTTING;

ARYLDIALKYLPHOSPHATASE; ASCORBIC ACID; CACO-2 CELLS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; I-KAPPA B PROTEINS; INTERFERON-GAMMA; INTESTINES; IRON; LIPID PEROXIDATION; LIPOPOLYSACCHARIDES; NF-KAPPA B; THIAZOLIDINEDIONES; TIME FACTORS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 63249089804     PISSN: 13572725     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biocel.2009.02.013     Document Type: Article

References (39)

1. Auboeuf D., Rieusset J., Fajas L., Vallier P., Frering V., Riou J.P., Staels B., Auwerx J., Laville M., and Vidal H. Tissue distribution and quantification of the expression of mRNAs of peroxisome proliferator-activated receptors and liver X receptor-alpha in humans: no alteration in adipose tissue of obese and NIDDM patients. Diabetes 46 (1997) 1319-1327
2. Aviram M., and Rosenblat M. Paraoxonases 1.2 and 3, oxidative stress, and macrophage foam cell formation during atherosclerosis development. Free Radic Biol Med 37 (2004) 1304-1316
3. Aviram M., and Rosenblat M. Paraoxonases and cardiovascular diseases: pharmacological and nutritional influences. Curr Opin Lipidol 16 (2005) 393-399
4. Bernotti S., Seidman E., Sinnett D., Brunet S., Dionne S., Delvin E., and Levy E. Inflammatory reaction without endogenous antioxidant response in Caco-2 cells exposed to iron/ascorbate-mediated lipid peroxidation. Am J Physiol Gastrointest Liver Physiol 285 (2003) G898-G906
5. Cario E., Rosenberg I.M., Brandwein S.L., Beck P.L., Reinecker H.C., and Podolsky D.K. Lipopolysaccharide activates distinct signaling pathways in intestinal epithelial cell lines expressing Toll-like receptors. J Immunol 164 (2000) 966-972
6. Chakravortty D., and Kumar K.S. Modulation of barrier function of small intestinal epithelial cells by lamina propria fibroblasts in response to lipopolysaccharide: possible role in TNFalpha in inducing barrier dysfunction. Microbiol Immunol 43 (1999) 527-533
7. Delerive P., Fruchart J.C., and Staels B. Peroxisome proliferator-activated receptors in inflammation control. J Endocrinol 169 (2001) 453-459
8. Draganov D.I., Teiber J.F., Speelman A., Osawa Y., Sunahara R., and La Du B.N. Human paraoxonases (PON1, PON2, and PON3) are lactonases with overlapping and distinct substrate specificities. J Lipid Res 46 (2005) 1239-1247
9. Fiocchi C. Inflammatory bowel disease: etiology and pathogenesis. Gastroenterology 115 (1998) 182-205
10. Fukushima K., Sasaki I., Takahashi K., Naito H., and Matsuno S. Lipopolysaccharide- and proinflammatory cytokine-induced energy production in intestinal and colonic epithelial cell lines. Scand J Gastroenterol 34 (1999) 291-296
11. Gouedard C., Koum-Besson N., Barouki R., and Morel Y. Opposite regulation of the human paraoxonase-1 gene PON-1 by fenofibrate and statins. Mol Pharmacol 63 (2003) 945-956
12. Grenier E., Maupas F.S., Beaulieu J.F., Seidman E., Delvin E., Sane A., Tremblay E., Garofalo C., and Levy E. Effect of retinoic acid on cell proliferation and differentiation as well as on lipid synthesis, lipoprotein secretion, and apolipoprotein biogenesis. Am J Physiol Gastrointest Liver Physiol 293 (2007) G1178-G1189
13. Khersonsky O., and Tawfik D.S. Structure-reactivity studies of serum paraoxonase PON1 suggest that its native activity is lactonase. Biochemistry 44 (2005) 6371-6382
14. Leblond J., Hubert-Buron A., Bole-Feysot C., Ducrotte P., Dechelotte P., and Coeffier M. Regulation of proteolysis by cytokines in the human intestinal epithelial cell line HCT-8: role of IFNgamma. Biochimie 88 (2006) 759-765
15. Lehmann G.L., Carreras F.I., Soria L.R., Gradilone S.A., and Marinelli R.A. LPS induces the TNF-alpha-mediated downregulation of rat liver aquaporin-8: role in sepsis-associated cholestasis. Am J Physiol Gastrointest Liver Physiol 294 (2008) G567-G575
16. Levy E., Menard D., Delvin E., Stan S., Mitchell G., Lambert M., Ziv E., Feoli-Fonseca J.C., and Seidman E. The polymorphism at codon 54 of the FABP2 gene increases fat absorption in human intestinal explants. J Biol Chem 276 (2001) 39679-39684
17. Levy E., Menard D., Suc I., Delvin E., Marcil V., Brissette L., Thibault L., and Bendayan M. Ontogeny, immunolocalisation, distribution and function of SR-BI in the human intestine. J Cell Sci 117 (2004) 327-337
18. Levy E., Trudel K., Bendayan M., Seidman E., Delvin E., Elchebly M., Lavoie J.C., Precourt L.P., Amre D., and Sinnett D. Biological role, protein expression, subcellular localization, and oxidative stress response of paraoxonase 2 in the intestine of humans and rats. Am J Physiol Gastrointest Liver Physiol 293 (2007) G1252-G1261
19. Lytle C., Tod T.J., Vo K.T., Lee J.W., Atkinson R.D., and Straus D.S. The peroxisome proliferator-activated receptor gamma ligand rosiglitazone delays the onset of inflammatory bowel disease in mice with interleukin 10 deficiency. Inflamm Bowel Dis 11 (2005) 231-243
20. Mackness M.I., Hallam S.D., Peard T., Warner S., and Walker C.H. The separation of sheep and human serum "A"-esterase activity into the lipoprotein fraction by ultracentrifugation. Comp Biochem Physiol B 82 (1985) 675-677
21. Marcil V., Delvin E., Seidman E., Poitras L., Zoltowska M., Garofalo C., and Levy E. Modulation of lipid synthesis, apolipoprotein biogenesis, and lipoprotein assembly by butyrate. Am J Physiol Gastrointest Liver Physiol 283 (2002) G340-G346
22. Meriin A.B., Gabai V.L., Yaglom J., Shifrin V.I., and Sherman M.Y. Proteasome inhibitors activate stress kinases and induce Hsp72. Diverse effects on apoptosis. J Biol Chem 273 (1998) 6373-6379
23. Mochizuki H., Scherer S.W., Xi T., Nickle D.C., Majer M., Huizenga J.J., Tsui L.C., and Prochazka M. Human PON2 gene at 7q21.3: cloning, multiple mRNA forms, and missense polymorphisms in the coding sequence. Gene 213 (1998) 149-157
24. Montoudis A., Seidman E., Boudreau F., Beaulieu J.F., Menard D., Elchebly M., Mailhot G., Sane A.T., Lambert M., Delvin E., and Levy E. Intestinal fatty acid binding protein regulates mitochondrion beta-oxidation and cholesterol uptake. J Lipid Res 49 (2008) 961-972
25. Ogle C.K., Guo X., Hasselgren P.O., Ogle J.D., and Alexander J.W. The gut as a source of inflammatory cytokines after stimulation with endotoxin. Eur J Surg 163 (1997) 45-51
26. Primo-Parmo S.L., Sorenson R.C., Teiber J., and La Du B.N. The human serum paraoxonase/arylesterase gene (PON1) is one member of a multigene family. Genomics 33 (1996) 498-507
27. Reddy S.T., Wadleigh D.J., Grijalva V., Ng C., Hama S., Gangopadhyay A., Shih D.M., Lusis A.J., Navab M., and Fogelman A.M. Human paraoxonase-3 is an HDL-associated enzyme with biological activity similar to paraoxonase-1 protein but is not regulated by oxidized lipids. Arterioscler Thromb Vasc Biol 21 (2001) 542-547
28. Ross R. Atherosclerosis-an inflammatory disease. N Engl J Med 340 (1999) 115-126
29. Sane A.T., Sinnett D., Delvin E., Bendayan M., Marcil V., Menard D., Beaulieu J.F., and Levy E. Localization and role of NPC1L1 in cholesterol absorption in human intestine. J Lipid Res 47 (2006) 2112-2120
30. Shah Y.M., Morimura K., and Gonzalez F.J. Expression of peroxisome proliferator-activated receptor-gamma in macrophage suppresses experimentally induced colitis. Am J Physiol Gastrointest Liver Physiol 292 (2007) G657-G666
31. Shamir R., Hartman C., Karry R., Pavlotzky E., Eliakim R., Lachter J., Suissa A., and Aviram M. Paraoxonases (PONs) 1, 2 and 3 are expressed in human and mouse gastrointestinal tract and in Caco-2 cell line: selective secretion of PON1 and PON2. Free Radic Biol Med 39 (2005) 336-344
32. Shiner M., Fuhrman B., and Aviram M. Macrophage paraoxonase 2 (PON2) expression is upregulated by unesterified cholesterol through activation of the phosphatidylinositol 3-kinase (PI3K) pathway. Biol Chem 388 (2007) 1353-1358
33. Siebenlist U., Franzoso G., and Brown K. Structure, regulation and function of NF-kappa B. Annu Rev Cell Biol 10 (1994) 405-455
34. Stadnyk A.W. Intestinal epithelial cells as a source of inflammatory cytokines and chemokines. Can J Gastroenterol 16 (2002) 241-246
35. Su C.G., Wen X., Bailey S.T., Jiang W., Rangwala S.M., Keilbaugh S.A., Flanigan A., Murthy S., Lazar M.A., and Wu G.D. A novel therapy for colitis utilizing PPAR-gamma ligands to inhibit the epithelial inflammatory response. J Clin Invest 104 (1999) 383-389
36. Trudel K., Sinnett D., James R.W., Delvin E., Amre D., Seidman E., and Levy E. Iron-ascorbic acid-induced oxidant stress and its quenching by paraoxonase 1 in HDL and the liver: comparison between humans and rats. J Cell Biochem 96 (2005) 404-411
37. Ulevitch R.J., and Tobias P.S. Recognition of Gram-negative bacteria and endotoxin by the innate immune system. Curr Opin Immunol 11 (1999) 19-22
38. Wang Q., Herrera-Ruiz D., Mathis A.S., Cook T.J., Bhardwaj R.K., and Knipp G.T. Expression of PPAR, RXR isoforms and fatty acid transporting proteins in the rat and human gastrointestinal tracts. J Pharm Sci 94 (2005) 363-372
39. Yin L., Laevsky G., and Giardina C. Butyrate suppression of colonocyte NF-kappa B activation and cellular proteasome activity. J Biol Chem 276 (2001) 44641-44646