ER stress and autophagy: New discoveries in the mechanism of action and drug resistance of the cyclin-dependent kinase inhibitor flavopiridol

Blood

Volumn 120, Issue 6, 2012, Pages 1262-1273

  Mahoney, Emilia ^a   Lucas, David M ^a   Gupta, Sneha V ^a,b   Wagner, Amy J ^a   Herman, Sarah E M ^a   Smith, Lisa L ^a   Yeh, Yuh Ying ^a   Andritsos, Leslie ^a   Jones, Jeffrey A ^a   Flynn, Joseph M ^a   Blum, Kristie A ^a   Zhang, Xiaoli ^b   Lehman, Amy ^b   Kong, Hui ^b   Gurcan, Metin ^b   Grever, Michael R ^a   Johnson, Amy J ^a,b   Byrd, John C ^a,b,c  

^a THE OHIO STATE UNIVERSITY WEXNER MEDICAL CENTER   (United States)

^b OHIO STATE UNIVERSITY   (United States)

^c B302 Starling Loving Hall   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

5 FLUORO 3 PHENYL 2 [1 (9H PURIN 6 YLAMINO)PROPYL] 3H QUINAZOLIN 4 ONE; APOPTOSIS SIGNAL REGULATING KINASE 1; CHLOROQUINE; FLAVOPIRIDOL; FLUDARABINE; PROTEIN IRE1; SMALL INTERFERING RNA; THAPSIGARGIN;

ARTICLE; AUTOPHAGY; CANCER RESISTANCE; CELL DEATH; CHRONIC LYMPHATIC LEUKEMIA; CONTROLLED STUDY; CYTOTOXICITY; DRUG MECHANISM; ENDOPLASMIC RETICULUM STRESS; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; PRIORITY JOURNAL;

EID: 84865183563     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2011-12-400184     Document Type: Article

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