Novel antiosteoclastogenic activity of phloretin antagonizing RANKL-induced osteoclast differentiation of murine macrophages

Molecular Nutrition and Food Research

Volumn 56, Issue 8, 2012, Pages 1223-1233

  Kim, Jung Lye ^a   Kang, Min Kyung ^a   Gong, Ju Hyun ^a   Park, Sin Hye ^a   Han, Seon Young ^a   Kang, Young Hee ^a  

^a Hallym University   (South Korea)

Author keywords

Bone resorption; Nuclear factor B; Osteoclastogenesis; Phloretin; Receptor activator of nuclear factor B ligand

Indexed keywords

ACID PHOSPHATASE; ACID PHOSPHATASE TARTRATE RESISTANT ISOENZYME; CARBONATE DEHYDRATASE; CATHEPSIN K; CTSK PROTEIN, MOUSE; GELATINASE B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; ISOENZYME; NFATC1 PROTEIN, MOUSE; OSTEOCLAST DIFFERENTIATION FACTOR; PHLORETIN; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE; SILIBININ; SILYMARIN; TARTRATE-RESISTANT ACID PHOSPHATASE; TNFSF11 PROTEIN, MOUSE; TRANSCRIPTION FACTOR NFAT; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 6;

ANIMAL; ARTICLE; CELL CULTURE; CELL DIFFERENTIATION; CYTOLOGY; DOSE RESPONSE; DRUG ANTAGONISM; DRUG EFFECT; GENETICS; MACROPHAGE; METABOLISM; MOUSE; OSTEOCLAST; OSTEOLYSIS; SECRETION (PROCESS);

ACID PHOSPHATASE; ANIMALS; BONE RESORPTION; CARBONIC ANHYDRASES; CATHEPSIN K; CELL DIFFERENTIATION; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; ISOENZYMES; MACROPHAGES; MATRIX METALLOPROTEINASE 9; MICE; NF-KAPPA B; NFATC TRANSCRIPTION FACTORS; OSTEOCLASTS; PHLORETIN; RANK LIGAND; SILYMARIN; TNF RECEPTOR-ASSOCIATED FACTOR 6; VACUOLAR PROTON-TRANSLOCATING ATPASES;

EID: 84865145501     PISSN: 16134125     EISSN: 16134133     Source Type: Journal    
DOI: 10.1002/mnfr.201100831     Document Type: Article

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