Dried plum polyphenols inhibit osteoclastogenesis by downregulating NFATc1 and inflammatory mediators

Calcified Tissue International

Volumn 82, Issue 6, 2008, Pages 475-488

  Bu, So Young ^a   Lerner, Megan ^b,c   Stoecker, Barbara J ^a   Boldrin, Emily ^a   Brackett, Daniel J ^b,c   Lucas, Edralin A ^a   Smith, Brenda J ^a,b  

^a OKLAHOMA STATE UNIVERSITY   (United States)

^b UNIVERSITY OF OKLAHOMA COLLEGE OF MEDICINE   (United States)

^c VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Antioxidant; Bone; Macrophage; Osteoclast; Osteoporosis

Indexed keywords

ACID PHOSPHATASE; INDUCIBLE NITRIC OXIDE SYNTHASE; LIPOPOLYSACCHARIDE; NITRIC OXIDE; OSTEOCLAST DIFFERENTIATION FACTOR; POLYPHENOL DERIVATIVE; PROSTAGLANDIN SYNTHASE; TARTARIC ACID; TRANSCRIPTION FACTOR NFAT; TUMOR NECROSIS FACTOR ALPHA; ACID PHOSPHATASE TARTRATE RESISTANT ISOENZYME; ANTIOXIDANT; AUTACOID; ENZYME INHIBITOR; FLAVONOID; HYDROGEN PEROXIDE; ISOENZYME; NFATC1 PROTEIN, MOUSE; NITRIC OXIDE SYNTHASE; PHENOL DERIVATIVE; PLANT EXTRACT; POLYPHENOLS; TARTRATE-RESISTANT ACID PHOSPHATASE;

ANIMAL CELL; ARTICLE; BONE MARROW CULTURE; CELL ACTIVITY; CELL DIFFERENTIATION; CELL MATURATION; DOWN REGULATION; DRUG MECHANISM; ENZYME INHIBITION; IMMUNITY; IMMUNOREGULATION; INFLAMMATION; MACROPHAGE; MEDIATOR; MOUSE; NONHUMAN; OSTEOCLAST; OSTEOLYSIS; OXIDATIVE STRESS; PLUM; PRIORITY JOURNAL; PROTEIN EXPRESSION; STEM CELL; TRANSCRIPTION REGULATION; ANIMAL; CELL LINE; CHEMISTRY; CYTOLOGY; DOSE RESPONSE; DRUG ANTAGONISM; DRUG EFFECT; GENETICS; METABOLISM; PRUNUS;

ACID PHOSPHATASE; ANIMALS; ANTIOXIDANTS; CELL DIFFERENTIATION; CELL LINE; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; ENZYME INHIBITORS; FLAVONOIDS; HYDROGEN PEROXIDE; INFLAMMATION MEDIATORS; ISOENZYMES; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; NFATC TRANSCRIPTION FACTORS; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; OSTEOCLASTS; PHENOLS; PLANT EXTRACTS; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; PRUNUS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 55249121151     PISSN: 0171967X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00223-008-9139-0     Document Type: Article

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