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Volumn 41, Issue 3, 2009, Pages 201-207

AMP kinase/cyclooxygenase-2 pathway regulates proliferation and apoptosis of cancer cells treated with quercetin

Author keywords

AMP activated protein kinases; Apoptosis; Cyclooxygenase 2; Growth inhibitors; HT 29 cells; Quercetin

Indexed keywords

ADENYLATE KINASE; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITOR; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; QUERCETIN;

EID: 65949121609     PISSN: 12263613     EISSN: 20926413     Source Type: Journal    
DOI: 10.3858/emm.2009.41.3.023     Document Type: Article
Times cited : (91)

References (26)
  • 1
    • 48949115243 scopus 로고    scopus 로고
    • The anti-obesity effect of quercetin is mediated by the AMPK and MAPK signaling pathways
    • Ahn J, Lee H, Kim S, Park J, Ha T. The anti-obesity effect of quercetin is mediated by the AMPK and MAPK signaling pathways. Biochem Biophys Res Commun 2008;373:545-549
    • (2008) Biochem Biophys Res Commun , vol.373 , pp. 545-549
    • Ahn, J.1    Lee, H.2    Kim, S.3    Park, J.4    Ha, T.5
  • 2
    • 33748468361 scopus 로고    scopus 로고
    • Differential modulation of cyclooxygenase-mediated prostaglandin production by the putative cancer chemopreventive flavonoids tricin, apigenin and quercetin
    • DOI 10.1007/s00280-006-0228-3
    • AI-Fayez M, Cai H, Tunstall R, Steward WP, Gescher AJ. Differential modulation of cyclooxygenase-mediated prostaglandin production by the putative cancer chemopreventive flavonoids tricin, apigenin and quercetin. Cancer Chemother Pharmacol 2006;58:816-825 (Pubitemid 44351263)
    • (2006) Cancer Chemotherapy and Pharmacology , vol.58 , Issue.6 , pp. 816-825
    • Al-Fayez, M.1    Cai, H.2    Tunstall, R.3    Steward, W.P.4    Gescher, A.J.5
  • 3
    • 22244486007 scopus 로고    scopus 로고
    • Curcumin inhibits the expression of COX-2 in UVB-irradiated human keratinocytes (HaCaT) by inhibiting activation of AP-1: P38 MAP kinase and JNK as potential upstream targets
    • Cho JW, Park K, Kweon R, Jang BC, Baek WK, Suh MH, Kim CW, Lee KS, Suh SI. Curcumin inhibits the expression of COX-2 in UVB-irradiated human keratinocytes (HaCaT) by inhibiting activation of AP-1: p38 MAP kinase and JNK as potential upstream targets. Exp Mol Med 2005;37:186-192 (Pubitemid 40992733)
    • (2005) Experimental and Molecular Medicine , vol.37 , Issue.3 , pp. 186-192
    • Cho, J.-W.1    Park, K.2    Kweon, G.R.3    Jang, B.-C.4    Baek, W.-K.5    Suh, M.-H.6    Kim, C.-W.7    Lee, K.-S.8    Suh, S.-I.9
  • 4
    • 4143124753 scopus 로고    scopus 로고
    • Signal transduction pathways regulating cyclooxygenase-2 expression: Potential molecular targets for chemoprevention
    • DOI 10.1016/j.bcp.2004.05.031, PII S000629520400365X
    • Chun KS, Surh YJ. Signal transduction pathways regulating cyclooxygenase-2 expression: potential molecular targets for chemoprevention. Biochem Pharmacol 2004;68:1089-1100 (Pubitemid 39099277)
    • (2004) Biochemical Pharmacology , vol.68 , Issue.6 , pp. 1089-1100
    • Chun, K.-S.1    Surh, Y.-J.2
  • 5
    • 35349016919 scopus 로고    scopus 로고
    • Chemoprevention of colorectal cancer
    • DOI 10.1159/000108394
    • Das D, Arber N, Jankowski JA. Chemoprevention of colorectal cancer. Digestion 2007;76:51-67 (Pubitemid 47608860)
    • (2007) Digestion , vol.76 , Issue.1 , pp. 51-67
    • Das, D.1    Arber, N.2    Jankowski, J.A.3
  • 7
    • 33751082422 scopus 로고    scopus 로고
    • Quercetin induces apoptosis via caspase activation, regulation of Bcl-2, and inhibition of PI-3-kinase/Akt and ERK pathways in a human hepatoma cell line (HepG2)
    • Granado-Serrano AB, Martin MA, Bravo L, Goya L, Ramos S. Quercetin induces apoptosis via caspase activation, regulation of Bcl-2, and inhibition of PI-3-kinase/Akt and ERK pathways in a human hepatoma cell line (HepG2). J Nutr 2006;136:2715-2721
    • (2006) J Nutr , vol.136 , pp. 2715-2721
    • Granado-Serrano, A.B.1    Martin, M.A.2    Bravo, L.3    Goya, L.4    Ramos, S.5
  • 8
    • 44649104448 scopus 로고    scopus 로고
    • Targeting AMPK: A new therapeutic opportunity in breast cancer
    • Hadad SM, Fleming S, Thompson AM. Targeting AMPK: A new therapeutic opportunity in breast cancer. Crit Rev Oncol Hematol 2008;67:1-7
    • (2008) Crit Rev Oncol Hematol , vol.67 , pp. 1-7
    • Hadad, S.M.1    Fleming, S.2    Thompson, A.M.3
  • 10
    • 19544385812 scopus 로고    scopus 로고
    • Combination of 5-fluorouracil and genistein induces apoptosis synergistically in chemo-resistant cancer cells through the modulation of AMPK and COX-2 signaling pathways
    • DOI 10.1016/j.bbrc.2005.04.143, PII S0006291X05009113
    • Hwang JT, Ha J, Park OJ. Combination of 5-fluorouracil and genistein induces apoptosis synergistically in chemoresistant cancer cells through the modulation of AMPK and COX-2 signaling pathways. Biochem Biophys Res Commun 2005;332:433-440 (Pubitemid 40731495)
    • (2005) Biochemical and Biophysical Research Communications , vol.332 , Issue.2 , pp. 433-440
    • Hwang, J.-T.1    Ha, J.2    Ock, J.P.3
  • 11
    • 33845789994 scopus 로고    scopus 로고
    • Apoptotic effect of EGCG in HT-29 colon cancer cells via AMPK signal pathway
    • DOI 10.1016/j.canlet.2006.03.030, PII S0304383506001960
    • Hwang JT, Ha J, Park IJ, Lee SK, Baik HW, Kim YM, Park OJ. Apoptotic effect of EGCG in HT-29 colon cancer cells via AMPK signal pathway. Cancer Lett 2007;247:115-121 (Pubitemid 46001507)
    • (2007) Cancer Letters , vol.247 , Issue.1-2 , pp. 115-121
    • Hwang, J.-T.1    Ha, J.2    Park, I.-J.3    Lee, S.-K.4    Baik, H.W.5    Kim, Y.M.6    Park, O.J.7
  • 12
    • 37549005069 scopus 로고    scopus 로고
    • Implication of AMP-activated protein kinase and Akt-regulated survivin in lung cancer chemopreventive activities of deguelin
    • Jin Q, Feng L, Behrens C, Bekele BN, Wistuba II, Hong WK, Lee HY. Implication of AMP-activated protein kinase and Akt-regulated survivin in lung cancer chemopreventive activities of deguelin. Cancer Res 2007;67:11630-11639
    • (2007) Cancer Res , vol.67 , pp. 11630-11639
    • Jin, Q.1    Feng, L.2    Behrens, C.3    Bekele, B.N.4    Wistuba, I.I.5    Hong, W.K.6    Lee, H.Y.7
  • 14
    • 34548553073 scopus 로고    scopus 로고
    • AMPK links energy status to cell structure and mitosis
    • DOI 10.1016/j.bbrc.2007.08.016, PII S0006291X07017214
    • Koh H, Chung J. AMPK links energy status to cell structure and mitosis. Biochem Biophys Res Commun 2007;362:789-792 (Pubitemid 47390643)
    • (2007) Biochemical and Biophysical Research Communications , vol.362 , Issue.4 , pp. 789-792
    • Koh, H.1    Chung, J.2
  • 18
    • 32544442362 scopus 로고    scopus 로고
    • COX inhibitors and breast cancer
    • DOI 10.1038/sj.bjc.6602942, PII 6602942
    • Mazhar D, Ang R, Wazman J. COX inhibitors and breast cancer. Br J Cancer 2006;94:346-350 (Pubitemid 43237558)
    • (2006) British Journal of Cancer , vol.94 , Issue.3 , pp. 346-350
    • Mazhar, D.1    Ang, R.2    Waxman, J.3
  • 19
    • 33745213627 scopus 로고    scopus 로고
    • AMPK and cell proliferation - AMPK as a therapeutic target for atherosclerosis and cancer
    • DOI 10.1113/jphysiol.2006.108324
    • Motochima H, Goldstein BJ, Igata M, Araki E. AMPK and cell proliferation-AMPK as a therapeutic target for atherosclerosis and cancer. J Physiol 2006;574:63-71 (Pubitemid 43905797)
    • (2006) Journal of Physiology , vol.574 , Issue.1 , pp. 63-71
    • Motoshima, H.1    Goldstein, B.J.2    Igata, M.3    Araki, E.4
  • 21
    • 48649095089 scopus 로고    scopus 로고
    • Cancer chemoprevention and chemotherapy: Dietary polyphenols and signaling pathways
    • Ramos S. Cancer chemoprevention and chemotherapy: dietary polyphenols and signaling pathways. Mol Nutr Food Res 2008;52:507-526
    • (2008) Mol Nutr Food Res , vol.52 , pp. 507-526
    • Ramos, S.1
  • 22
    • 34447283477 scopus 로고    scopus 로고
    • Ins and outs of dietary phytochemicals in cancer chemoprevention
    • DOI 10.1016/j.bcp.2007.02.014, PII S000629520700127X
    • Russo GL. Ins and outs of dietary phytochemicals in cancer chemoprevention. Biochem Pharmacol 2007;74:533-544 (Pubitemid 47042006)
    • (2007) Biochemical Pharmacology , vol.74 , Issue.4 , pp. 533-544
    • Russo, G.L.1
  • 24
    • 34250694982 scopus 로고    scopus 로고
    • 5-Aminoimidazole-4-carboxamide riboside sensitizes TRAIL- And TNFα-induced cytotoxicity in colon cancer cells through AMP-activated protein kinase signaling
    • DOI 10.1158/1535-7163.MCT-06-0800
    • Su RY, Chao Y, Chen TY, Huang DY, Lin WW. 5-Aminoimidazole-4-carboxamide riboside sensitizes TRAIL- and TNFα-induced cytotoxicity in colon cancer cells through AMP-activated protein kinase signaling. Mol Cancer Ther 2007;6:1562-1571 (Pubitemid 46954023)
    • (2007) Molecular Cancer Therapeutics , vol.6 , Issue.5 , pp. 1562-1571
    • Su, R.-Y.1    Chao, Y.2    Chen, T.-Y.3    Huang, D.-Y.4    Lin, W.-W.5
  • 25
    • 33845705480 scopus 로고    scopus 로고
    • Dietary polyphenolic phytochemicals-promising cancer chemopreventive agents in humans? A review of their clinical properties
    • Thomasset SC, Berry DP, Garcea G, Marczylo T, Steward WP, Gescher AJ. Dietary polyphenolic phytochemicals-promising cancer chemopreventive agents in humans? A review of their clinical properties. Int J Cancer 2007;120:451-458
    • (2007) Int J Cancer , vol.120 , pp. 451-458
    • Thomasset, S.C.1    Berry, D.P.2    Garcea, G.3    Marczylo, T.4    Steward, W.P.5    Gescher, A.J.6
  • 26
    • 0141863169 scopus 로고    scopus 로고
    • Biphasic modulation of cell proliferation by quercetin at concentrations physiologically relevant in humans
    • DOI 10.1016/S0304-3835(03)00412-9
    • Van der Woude H, Gliszczynska-Swinlo A, Struijs K, Smmets A, Alink GM, Rietjens IM. Biphasic modulation of cell proliferation by quercetin at concentrations physiologically relevant in humans. Cancer Let 2003;200:41-47 (Pubitemid 37222357)
    • (2003) Cancer Letters , vol.200 , Issue.1 , pp. 41-47
    • Van Der Woude, H.1    Gliszczynska-Swigl2    o, A.3    Struijs, K.4    Smeets, A.5    Alink, G.M.6    Rietjens, I.M.C.M.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.