N-acetyltransferase polymorphism and risk of colorectal adenoma and cancer: A pooled analysis of variations from 59 studies

PLoS ONE

Volumn 7, Issue 8, 2012, Pages

  Liu, Jinxin ^a,b   Ding, Dapeng ^a   Wang, Xiaoxue ^c   Chen, Yizhi ^b   Li, Rong ^a   Zhang, Ying ^d   Luo, Rongcheng ^a  

^a SOUTHERN MEDICAL UNIVERSITY   (China)

^b Affiliated to Guangzhou University of Traditional Chinese Medicine   (China)

^c THE SIXTH AFFILIATED HOSPITAL OF SUN YAT SEN UNIVERSITY   (China)

^d JINAN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ARYLAMINE ACETYLTRANSFERASE;

ARTICLE; CANCER LOCALIZATION; CANCER RISK; CASE CONTROL STUDY; COLORECTAL ADENOMA; CONTROLLED STUDY; DNA POLYMORPHISM; ETHNIC DIFFERENCE; GENE FREQUENCY; GENETIC ASSOCIATION; GENETIC RISK; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; GENOTYPE; HUMAN; N ACETYLTRANSFERASE 1 GENE; N ACETYLTRANSFERASE 2 GENE; ONCOGENE; RISK ASSESSMENT;

ACETYLTRANSFERASES; ADENOMA; ARYLAMINE N-ACETYLTRANSFERASE; CASE-CONTROL STUDIES; COHORT STUDIES; COLORECTAL NEOPLASMS; GENE EXPRESSION REGULATION, NEOPLASTIC; GENETIC PREDISPOSITION TO DISEASE; GENETIC VARIATION; GENOTYPE; HUMANS; ISOENZYMES; POLYMORPHISM, GENETIC; RISK;

EID: 84865061002     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0042797     Document Type: Article

References (54)

1. Tsong WH, Koh WP, Yuan JM, Wang R, Sun CL, et al. ((2007)) Cigarettes and alcohol in relation to colorectal cancer: the Singapore Chinese Health Study. Br J Cancer 96:: 821--827.
2. DeMarini DM, ((2004)) Genotoxicity of tobacco smoke and tobacco smoke condensate: a review. Mutat Res 567:: 447--474.
3. Hirvonen A, ((1999)) Polymorphic NATs and cancer predisposition. IARC Sci Publ pp. 251--270.
4. Brockton N, Little J, Sharp L, Cotton SC, ((2000)) N-acetyltransferase polymorphisms and colorectal cancer: a HuGE review. Am J Epidemiol 151:: 846--861.
5. Bell DA, Stephens EA, Castranio T, Umbach DM, Watson M, et al. ((1995)) Polyadenylation polymorphism in the acetyltransferase 1 gene (NAT1) increases risk of colorectal cancer. Cancer Res 55:: 3537--3542.
6. Probst-Hensch NM, Haile RW, Li DS, Sakamoto GT, Louie AD, et al. ((1996)) Lack of association between the polyadenylation polymorphism in the NAT1 (acetyltransferase 1) gene and colorectal adenomas. Carcinogenesis 17:: 2125--2129.
7. Welfare MR, Cooper J, Bassendine MF, Daly AK, ((1997)) Relationship between acetylator status, smoking, and diet and colorectal cancer risk in the north-east of England. Carcinogenesis 18:: 1351--1354.
8. Chen J, Stampfer MJ, Hough HL, Garcia-Closas M, Willett WC, et al. ((1998)) A prospective study of N-acetyltransferase genotype, red meat intake, and risk of colorectal cancer. Cancer Res 58:: 3307--3311.
9. Hubbard AL, Moyes C, Wyllie AH, Smith CA, Harrison DJ, ((1998)) N-acetyl transferase 1: two polymorphisms in coding sequence identified in colorectal cancer patients. Br J Cancer 77:: 913--916.
10. Gil JP, Lechner MC, ((1998)) Increased frequency of wild-type arylamine-N-acetyltransferase allele NAT2*4 homozygotes in Portuguese patients with colorectal cancer. Carcinogenesis 19:: 37--41.
11. Lee EJ, Zhao B, Seow-Choen F, ((1998)) Relationship between polymorphism of N-acetyltransferase gene and susceptibility to colorectal carcinoma in a Chinese population. Pharmacogenetics 8:: 513--517.
12. Kampman E, Slattery ML, Bigler J, Leppert M, Samowitz W, et al. ((1999)) Meat consumption, genetic susceptibility, and colon cancer risk: a United States multicenter case-control study. Cancer Epidemiol Biomarkers Prev 8:: 15--24.
13. Potter JD, Bigler J, Fosdick L, Bostick RM, Kampman E, et al. ((1999)) Colorectal adenomatous and hyperplastic polyps: smoking and N-acetyltransferase 2 polymorphisms. Cancer Epidemiol Biomarkers Prev 8:: 69--75.
14. Katoh T, Boissy R, Nagata N, Kitagawa K, Kuroda Y, et al. ((2000)) Inherited polymorphism in the N-acetyltransferase 1 (NAT1) and 2 (NAT2) genes and susceptibility to gastric and colorectal adenocarcinoma. Int J Cancer 85:: 46--49.
15. Agundez J, Lozano L, Ladero JM, Sastre J, Cerdan FJ, et al. ((2000)) N-acetyltransferase 2 (NAT2) genotype and colorectal carcinoma: risk variability according to tumour site? Scand J Gastroenterol 35:: 1087--1091.
16. Ishibe N, Sinha R, Hein DW, Kulldorff M, Strickland P, et al. ((2002)) Genetic polymorphisms in heterocyclic amine metabolism and risk of colorectal adenomas. Pharmacogenetics 12:: 145--150.
17. Tiemersma EW, Kampman E, Bueno DMH, Bunschoten A, van Schothorst EM, et al. ((2002)) Meat consumption, cigarette smoking, and genetic susceptibility in the etiology of colorectal cancer: results from a Dutch prospective study. Cancer Causes Control 13:: 383--393.
18. Barrett JH, Smith G, Waxman R, Gooderham N, Lightfoot T, et al. ((2003)) Investigation of interaction between N-acetyltransferase 2 and heterocyclic amines as potential risk factors for colorectal cancer. Carcinogenesis 24:: 275--282.
19. van der Hel OL, Bueno DMH, Sandkuijl L, van Noord PA, Pearson PL, et al. ((2003)) Rapid N-acetyltransferase 2 imputed phenotype and smoking may increase risk of colorectal cancer in women (Netherlands). Cancer Causes Control 14:: 293--298.
20. van der Hel OL, Bueno DMH, Roest M, Slothouber B, van Gils C, et al. ((2003)) No modifying effect of NAT1, GSTM1, and GSTT1 on the relation between smoking and colorectal cancer risk. Cancer Epidemiol Biomarkers Prev 12:: 681--682.
21. Kiss I, Nemeth A, Bogner B, Pajkos G, Orsos Z, et al. ((2004)) Polymorphisms of glutathione-S-transferase and arylamine N-acetyltransferase enzymes and susceptibility to colorectal cancer. Anticancer Res 24:: 3965--3970.
22. Tiemersma EW, Voskuil DW, Bunschoten A, Hogendoorn EA, Witteman BJ, et al. ((2004)) Risk of colorectal adenomas in relation to meat consumption, meat preparation, and genetic susceptibility in a Dutch population. Cancer Causes Control 15:: 225--236.
23. He LJ, Yu YM, Qiao F, Liu JS, Sun XF, et al. ((2005)) Genetic polymorphisms of N-acetyltransferase 2 and colorectal cancer risk. World J Gastroenterol 11:: 4268--4271.
24. Landi S, Gemignani F, Moreno V, Gioia-Patricola L, Chabrier A, et al. ((2005)) A comprehensive analysis of phase I and phase II metabolism gene polymorphisms and risk of colorectal cancer. Pharmacogenet Genomics 15:: 535--546.
25. Chen K, Jin MJ, Fan CH, Song L, Jiang QT, et al. ((2005)) [A case-control study on the association between genetic polymorphisms of metabolic enzymes and the risk of colorectal cancer]. Zhonghua Liu Xing Bing Xue Za Zhi 26:: 659--664.
26. Chan AT, Tranah GJ, Giovannucci EL, Willett WC, Hunter DJ, et al. ((2005)) Prospective study of N-acetyltransferase-2 genotypes, meat intake, smoking and risk of colorectal cancer. Int J Cancer 115:: 648--652.
27. Moslehi R, Chatterjee N, Church TR, Chen J, Yeager M, et al. ((2006)) Cigarette smoking, N-acetyltransferase genes and the risk of advanced colorectal adenoma. Pharmacogenomics 7:: 819--829.
28. Lilla C, Verla-Tebit E, Risch A, Jager B, Hoffmeister M, et al. ((2006)) Effect of NAT1 and NAT2 genetic polymorphisms on colorectal cancer risk associated with exposure to tobacco smoke and meat consumption. Cancer Epidemiol Biomarkers Prev 15:: 99--107.
29. Borlak J, Reamon-Buettner SM, ((2006)) N-acetyltransferase 2 (NAT2) gene polymorphisms in colon and lung cancer patients. BMC Med Genet 7:: 58.
30. Pistorius S, Goergens H, Engel C, Plaschke J, Krueger S, et al. ((2007)) N-Acetyltransferase (NAT) 2 acetylator status and age of tumour onset in patients with sporadic and familial, microsatellite stable (MSS) colorectal cancer. Int J Colorectal Dis 22:: 137--143.
31. Huang CC, Chien WP, Wong RH, Cheng YW, Chen MC, et al. ((2007)) NAT2 fast acetylator genotype is associated with an increased risk of colorectal cancer in Taiwan. Dis Colon Rectum 50:: 981--989.
32. Mahid SS, Colliver DW, Crawford NP, Martini BD, Doll MA, et al. ((2007)) Characterization of N-acetyltransferase 1 and 2 polymorphisms and haplotype analysis for inflammatory bowel disease and sporadic colorectal carcinoma. BMC Med Genet 8:: 28.
33. Yoshida K, Osawa K, Kasahara M, Miyaishi A, Nakanishi K, et al. ((2007)) Association of CYP1A1, CYP1A2, GSTM1 and NAT2 gene polymorphisms with colorectal cancer and smoking. Asian Pac J Cancer Prev 8:: 438--444.
34. Butler LM, Millikan RC, Sinha R, Keku TO, Winkel S, et al. ((2008)) Modification by N-acetyltransferase 1 genotype on the association between dietary heterocyclic amines and colon cancer in a multiethnic study. Mutat Res 638:: 162--174.
35. Shin A, Shrubsole MJ, Rice JM, Cai Q, Doll MA, et al. ((2008)) Meat intake, heterocyclic amine exposure, and metabolizing enzyme polymorphisms in relation to colorectal polyp risk. Cancer Epidemiol Biomarkers Prev 17:: 320--329.
36. Sorensen M, Autrup H, Olsen A, Tjonneland A, Overvad K, et al. ((2008)) Prospective study of NAT1 and NAT2 polymorphisms, tobacco smoking and meat consumption and risk of colorectal cancer. Cancer Lett 266:: 186--193.
37. Cotterchio M, Boucher BA, Manno M, Gallinger S, Okey AB, et al. ((2008)) Red meat intake, doneness, polymorphisms in genes that encode carcinogen-metabolizing enzymes, and colorectal cancer risk. Cancer Epidemiol Biomarkers Prev 17:: 3098--3107.
38. Yeh CC, Sung FC, Tang R, Chang-Chieh CR, Hsieh LL, ((2009)) Polymorphisms of cytochrome P450 1A2 and N-acetyltransferase genes, meat consumption, and risk of colorectal cancer. Dis Colon Rectum 52:: 104--111.
39. Nothlings U, Yamamoto JF, Wilkens LR, Murphy SP, Park SY, et al. ((2009)) Meat and heterocyclic amine intake, smoking, NAT1 and NAT2 polymorphisms, and colorectal cancer risk in the multiethnic cohort study. Cancer Epidemiol Biomarkers Prev 18:: 2098--2106.
40. Zupa A, Sgambato A, Bianchino G, Improta G, Grieco V, et al. ((2009)) GSTM1 and NAT2 polymorphisms and colon, lung and bladder cancer risk: a case-control study. Anticancer Res 29:: 1709--1714.
41. Wang H, Yamamoto JF, Caberto C, Saltzman B, Decker R, et al. ((2011)) Genetic variation in the bioactivation pathway for polycyclic hydrocarbons and heterocyclic amines in relation to risk of colorectal neoplasia. Carcinogenesis 32:: 203--209.
42. Da ST, Felipe AV, de Lima JM, Oshima CT, Forones NM, ((2011)) N-Acetyltransferase 2 genetic polymorphisms and risk of colorectal cancer. World J Gastroenterol 17:: 760--765.
43. Cleary SP, Cotterchio M, Shi E, Gallinger S, Harper P, ((2010)) Cigarette smoking, genetic variants in carcinogen-metabolizing enzymes, and colorectal cancer risk. Am J Epidemiol 172:: 1000--1014.
44. Whiting P, Weswood ME, Rutjes AW, Reitsma JB, Bossuyt PM, et al. ((2006)) Evaluation of QUADAS, a tool for the quality assessment of diagnostic accuracy studies. BMC Med Res Methodol 6:: 9.
45. Lamberti C, Jungck M, Laarmann M, Knapp M, Caspari R, et al. ((2002)) Arylamine N-acetyltransferase type 2 and glutathione S-transferases M1 and T1 polymorphisms in familial adenomatous polyposis. Pharmacogenetics 12:: 49--54.
46. Voskuil DW, Kampman E, Grubben MJ, Goldbohm RA, Brants HA, et al. ((1997)) Meat consumption and preparation, and genetic susceptibility in relation to colorectal adenomas. Cancer Lett 114:: 309--311.
47. Osian G, Procopciuc L, Vlad L, ((2006)) NAT2 gene polymorphism and sporadic colorectal cancer. Prevalence, tumor stage and prognosis. A preliminary study in 70 patients. J Gastrointestin Liver Dis 15:: 347--353.
48. Roemer HC, Weistenhofer W, Lohlein D, Geller F, Blomeke B, et al. ((2008)) N-acetyltransferase 1 in colon and rectal cancer cases from an industrialized area. J Toxicol Environ Health A 71:: 902--905.
49. Le Marchand L, Sivaraman L, Franke AA, Custer LJ, Wilkens LR, et al. ((1996)) Predictors of N-acetyltransferase activity: should caffeine phenotyping and NAT2 genotyping be used interchangeably in epidemiological studies? Cancer Epidemiol Biomarkers Prev 5:: 449--455.
50. Probst-Hensch NM, Haile RW, Ingles SA, Longnecker MP, Han CY, et al. ((1995)) Acetylation polymorphism and prevalence of colorectal adenomas. Cancer Res 55:: 2017--2020.
51. Bamshad M, Wooding S, Salisbury BA, Stephens JC, ((2004)) Deconstructing the relationship between genetics and race. Nat Rev Genet 5:: 598--609.
52. Lichtenstein P, Holm NV, Verkasalo PK, Iliadou A, Kaprio J, et al. ((2000)) Environmental and heritable factors in the causation of cancer analyses of cohorts of twins from Sweden, Denmark, and Finland. N Engl J Med 343:: 78--85.
53. World Cancer Research Fund AIfCR. (2007) Food, nutrition, physical activity, and the prevention of cancer: a global perspective. Washington DC: AICR.
54. Ye Z, Parry JM, ((2002)) Meta-analysis of 20 case-control studies on the N-acetyltransferase 2 acetylation status and colorectal cancer risk. Med Sci Monit 8:: 558--565.