Opticin exerts its anti-angiogenic activity by regulating extracellular matrix adhesiveness

Journal of Biological Chemistry

Volumn 287, Issue 33, 2012, Pages 28027-28036

  Le Goff, Magali M ^a   Sutton, Matthew J ^a   Slevins, Mark ^d,e   Latif, Ayse ^a,c   Humphries, Martin J ^b   Bishop, Paul N ^a,c  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b UNIVERSITY OF MANCHESTER   (United Kingdom)

^c MANCHESTER ROYAL EYE HOSPITAL   (United Kingdom)

^d MANCHESTER METROPOLITAN UNIVERSITY   (United Kingdom)

^e HOSPITAL DE LA SANTA CREU I SANT PAU   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOGENESIS; ANTI-ANGIOGENIC ACTIVITY; CAPILLARY MORPHOGENESIS; CAPILLARY NETWORK; CELL INTERACTION; CHICK CHORIOALLANTOIC MEMBRANE; EX-VIVO; EXTRACELLULAR MATRICES; GROWTH FACTOR; INTEGRINS; UNDERLYING MECHANISM; VITREOUS HUMOR;

ENDOTHELIAL CELLS; GLYCOPROTEINS;

COLLAGEN;

COLLAGEN; COLLAGEN TYPE 1; COLLAGEN TYPE 2; COLLAGEN TYPE 4; LAMININ; MATRIGEL; OPTICIN; SCLEROPROTEIN; UNCLASSIFIED DRUG; VERY LATE ACTIVATION ANTIGEN 1; VERY LATE ACTIVATION ANTIGEN 2; VITRONECTIN;

ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIANGIOGENIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; BIOTINYLATION; CELL ADHESION; CELL INVASION; CELL PROLIFERATION; CHORIOALLANTOIS; CONTROLLED STUDY; DRUG PROTEIN BINDING; EXTRACELLULAR MATRIX; MORPHOGENESIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; RETINOPATHY; SIGNAL TRANSDUCTION;

ANGIOGENESIS INHIBITORS; ANIMALS; CATTLE; CELL ADHESION; CELL LINE, TUMOR; COLLAGEN; DISEASE MODELS, ANIMAL; EXTRACELLULAR MATRIX PROTEINS; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; INTEGRIN ALPHA1BETA1; INTEGRIN ALPHA2BETA1; MICE; NEOVASCULARIZATION, PATHOLOGIC; OXYGEN; PROTEIN BINDING; PROTEOGLYCANS; RETINAL DISEASES; SIGNAL TRANSDUCTION;

EID: 84865020080     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.331157     Document Type: Article

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