Detection of microsatellite instability in colorectal cancer using an alternative multiplex assay of quasi-monomorphic mononucleotide markers

Journal of Molecular Diagnostics

Volumn 10, Issue 2, 2008, Pages 154-159

  Deschoolmeester, Vanessa ^a   Baay, Marc ^a   Wuyts, Wim ^a   Van Marck, Eric ^b   Van Damme, Nancy ^c   Vermeulen, Peter ^a   Lukaszuk, Krzysztof ^d   Lardon, Filip ^a   Vermorken, Jan B ^a  

^a UNIVERSITY OF ANTWERP   (Belgium)

^b ANTWERP UNIVERSITY HOSPITAL   (Belgium)

^c GHENT UNIVERSITY HOSPITAL   (Belgium)

^d UNIVERSITY OF GDA SK   (Poland)

Author keywords

[No Author keywords available]

Indexed keywords

GENOMIC DNA; MICROSATELLITE DNA; MONONUCLEOTIDE; NUCLEOTIDE; PROTEIN MLH1; PROTEIN MSH2; PROTEIN MSH6; UNCLASSIFIED DRUG;

ALLELE; ARTICLE; CANCER DIAGNOSIS; COLORECTAL CANCER; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DIAGNOSTIC PROCEDURE; GENETIC ANALYSIS; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MICROSATELLITE INSTABILITY; MULTIPLEX POLYMERASE CHAIN REACTION; PROGNOSIS;

EID: 41149155274     PISSN: 15251578     EISSN: None     Source Type: Journal    
DOI: 10.2353/jmoldx.2008.070087     Document Type: Article

References (28)

1. Lawes DA, SenGupta S, Boulos PB: The clinical importance and prognostic implications of microsatellite instability in sporadic cancer. Eur J Surg Oncol 2003, 29:201-212
2. Ribic CM, Sargent DJ, Moore MJ, Thibodeau SN, French AJ, Goldberg RM, Hamilton SR, Laurent Puig P, Gryfe R, Shepherd LE, Tu D, Redston M, Gallinger S: Tumor microsatellite-instability status as a predictor of benefit from fluorouracil-based adjuvant chemotherapy for colon cancer. N Engl J Med 2003, 349:247-257
3. Ewald J, Rodrigue CM, Mourra N, Lefevre JH, Flejou JF, Tiret E, Gespach C, Parc YR: Immunohistochemical staining for mismatch repair proteins, and its relevance in the diagnosis of hereditary nonpolyposis colorectal cancer. Br J Surg 2007, 94:1020-1027
4. Chapusot C, Martin L, Puig P, Ponnelle T, Cheynel N, Bouvier A, Rageot D, Roignot P, Rat P, Faivre J, Piard F: What is the best way to assess microsatellite instability status in colorectal cancer? Study on a population base of 462 colorectal cancers. Am J Surg Pathol 2004, 28:1553-1559
5. Locker G, Hamilton S, Harris J, Jessup J, Kemeny N, Macdonald J, Somerfield M, Hayes D, Bast R: ASCO 2006 update of recommendations for the use of tumor markers in gastrointestinal cancer. J Clin Oncol 2006, 24:5313-5327
6. Murphy K, Zhang S, Geiger T, Hafez M, Bacher J, Berg K, Eshleman J: Comparison of the microsatellite instability analysis system and the Bethesda panel for the determination of microsatellite instability in colorectal cancers. J Mol Diagn 2006, 8:305-311
7. Boland CR, Thibodeau SN, Hamilton SR, Sidransky D, Eshleman JR, Burt RW, Meltzer SJ, Rodriguez Bigas MA, Fodde R, Ranzani GN, Srivastava S: A National Cancer Institute workshop on microsatellite instability for cancer detection and familial predisposition: development of international criteria for the determination of microsatellite instability in colorectal cancer. Cancer Res 1998, 58:5248-5257
8. Umar A, Boland CR, Terdiman JP, Syngal S, de la Chapelle A, Ruschoff J, Fishel R, Lindor NM, Burgart LJ, Hamelin R, Hamilton SR, Hiatt RA, Jass J, Lindblom A, Lynch HT, Peltomaki P, Ramsey SD, Rodriguez Bigas MA, Vasen HFA, Hawk ET, Barrett JC, Freedman AN, Srivastava S: Revised Bethesda guidelines for hereditary nonpolyposis colorectal cancer (Lynch syndrome) and microsatellite instability. J Natl Cancer Inst 2004, 96:261-268
9. Suraweera N, Duval A, Reperant M, Vaury C, Furlan D, Leroy K, Seruca R, Iacopetta B, Hamelin R: Evaluation of tumor microsatellite instability using five quasi monomorphic mononucleotide repeats and pentaplex PCR. Gastroenterology 2002, 123:1804-1811
10. Bacher J, Flanagan L, Smalley R, Nassif N, Burgart L, Halberg R, Megid W, Thibodeau S: Development of a fluorescent multiplex assay for detection of MSI-high tumors. Dis Markers 2004, 20:237-250
11. Buhard O, Cattaneo F, Wong Y, Yim S, Friedman E, Flejou J, Duval A, Hamelin R: Multipopulation analysis of polymorphisms in five mononucleotide repeats used to determine the microsatellite instability status of human tumors. J Clin Oncol 2006, 24:241-251
12. Xicola RM, Llor X, Pons E, Castells A, Alenda C, Pinol V, Andreu M, Castellvi-Bel S, Paya A, Jover R, Bessa X, Giros A, Duque JM, Nicolas-Perez D, Garcia AM, Rigau J, Gassull MA: Performance of different microsatellite marker panels for detection of mismatch repair-deficient colorectal tumors. J Natl Cancer Inst 2007, 99:244-252
13. Zhou X, Hoang J, Li Y, Seruca R, Carneiro F, Sobrinho Simoes M, Lothe R, Gleeson C, Russell S, Muzeau F, Flejou J, Hoang Xuan K, Lidereau R, Thomas G, Hamelin R: Determination of the replication error phenotype in human tumors without the requirement for matching normal DNA by analysis of mononucleotide repeat microsatellites. Genes Chromosomes Cancer 1998, 21:101-107
14. Morifuji M, Hiyama E, Murakami Y, Imamura Y, Sueda T, Yokoyama T: Fluorescent-based BAT-26 analysis for distinct screening of microsatellite instability in colorectal cancers. Int J Oncol 2003, 22:807-813
15. Woerner SM, Gebert J, Yuan YP, Sutter C, Ridder R, Bork P, Doeberitz MV: Systematic identification of genes with coding microsatellites mutated in DNA mismatch repair-deficient cancer cells. Int J Cancer 2001, 93:12-19
16. Findeisen P, Kloor M, Merx S, Sutter C, Woerner S, Dostmann N, Benner A, Dondog B, Pawlita M, Dippold W, Wagner R, Gebert J, von Knebel Doeberitz M: T25 repeat in the 3′ untranslated region of the CASP2 gene: a sensitive and specific marker for microsatellite instability in colorectal cancer. Cancer Res 2005, 65:8072-8078
17. Henegariu O, Heerema N, Dlouhy S, Vance G, Vogt P: Multiplex PCR: critical parameters and step-by-step protocol. Biotechniques 1997, 23:504-511
18. Deschoolmeester V, Baay M, Wuyts W, Van Marck E, V, Pelckmans P, Lardon F, Vermorken J: Comparison of three commonly used PCR-based techniques to analyze MSI status in sporadic colorectal cancer. J Clin Lab Anal 2006, 20:52-61
19. Hoang J, Cottu P, Thuille B, Salmon R, Thomas G, Hamelin R: BAT-26, an indicator of the replication error phenotype in colorectal cancers and cell lines. Cancer Res 1997, 57:300-303
20. Brennetot C, Buhard O, Jourdan F, Flejou J, Duval A, Hamelin R: Mononucleotide repeats BAT-26 and BAT-25 accurately detect MSI-H tumors and predict tumor content: implications for population screening. Int J Cancer 2005, 113:446-450
21. Pyatt R, Chadwick RB, Johnson CK, Adebamowo C, de la Chapelle A, Prior TW: Polymorphic variation at the BAT-25 and BAT-26 loci in individuals of African origin. Implications for microsatellite instability testing. Am J Pathol 1999, 155:349-353
22. Bacher J, Abdel Megid W, Kent First M, Halberg R: Use of mononucleotide repeat markers for detection of microsatellite instability in mouse tumors. Mol Carcinog 2005, 44:285-292
23. Zhou X, Hoang J, Cottu P, Thomas G, Hamelin R: Allelic profiles of mononucleotide repeat microsatellites in control individuals and in colorectal tumors with and without replication errors. Oncogene 1997, 15:1713-1718
24. Blake C, Tsao J, Wu A, Shibata D: Stepwise deletions of polyA sequences in mismatch repair-deficient colorectal cancers. Am J Pathol 2001, 158:1867-1870
25. Loukola A, Eklin K, Laiho P, Salovaara R, Kristo P, Jarvinen H, Mecklin JP, Launonen V, Aaltonen LA: Microsatellite marker analysis in screening for hereditary nonpolyposis colorectal cancer (HNPCC). Cancer Res 2001, 61:4545-4549
26. Whitehall V, Walsh M, Young J, Leggett B, Jass J: Methylation of O-6-methylguanine DNA methyltransferase characterizes a subset of colorectal cancer with low-level DNA microsatellite instability. Cancer Res 2001, 61:827-830
27. Parc YR, Hailing KC, Wang L, Christensen ER, Cunningham JM, French AJ, Burgart LJ, Price-Troska TL, Roche PC, Thibodeau SN: HMSH6 alterations in patients with microsatellite instability-low colorectal cancer. Cancer Res 2000, 60:2225-2231
28. Laiho P, Launonen V, Lahermo P, Esteller M, Guo MZ, Herman JG, Mecklin JP, Jarvinen H, Sistonen P, Kim KM, Shibata D, Houlston RS, Aaltonen LA: Low-level microsatellite instability in most colorectal carcinomas. Cancer Res 2002, 62:1166-1170