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Volumn 223, Issue 1, 2010, Pages 27-35

Ex vivo expansion of human mesenchymal stem cells: A more effective cell proliferation kinetics and metabolism under hypoxia

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CELL COUNT; CELL CULTURE; CELL DIFFERENTIATION; CELL DIVISION; CELL GROWTH; CELL KINETICS; CELL LABELING; CELL METABOLISM; CELL PROLIFERATION; CONTROLLED STUDY; EX VIVO STUDY; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; HYPOXIA; IMMUNOPHENOTYPING; MESENCHYMAL STEM CELL; OXYGEN TENSION; PRIORITY JOURNAL; STEM CELL EXPANSION;

EID: 75749145078     PISSN: 00219541     EISSN: 10974652     Source Type: Journal    
DOI: 10.1002/jcp.21987     Document Type: Article
Times cited : (257)

References (36)
  • 1
    • 34548312133 scopus 로고    scopus 로고
    • Analysis of kinetic, stoichiometry and regulation of glucose and glutamine metabolism in hybridoma batch cultures using logistic equations
    • Acosta ML, Sanchez A, Garcia F, Contreras A, Molina E. 2007. Analysis of kinetic, stoichiometry and regulation of glucose and glutamine metabolism in hybridoma batch cultures using logistic equations. Cytotechnology 54:189-200.
    • (2007) Cytotechnology , vol.54 , pp. 189-200
    • Acosta, M.L.1    Sanchez, A.2    Garcia, F.3    Contreras, A.4    Molina, E.5
  • 2
    • 1542358860 scopus 로고    scopus 로고
    • Direct cell contact influences bone marrow mesenchymal stem cell fate
    • Ball SG, Shuttleworth AC, Kielty CM. 2004. Direct cell contact influences bone marrow mesenchymal stem cell fate. Int J Biochem Cell Biol 36:714-727.
    • (2004) Int J Biochem Cell Biol , vol.36 , pp. 714-727
    • Ball, S.G.1    Shuttleworth, A.C.2    Kielty, C.M.3
  • 3
    • 4444273090 scopus 로고    scopus 로고
    • Study of telomere length reveals rapid aging of human marrow stromal cells following in vitro expansion
    • Baxter MA, Wynn RF, Jowitt SN, Wraith JE, Fairbairn LJ, Bellantuono I. 2004. Study of telomere length reveals rapid aging of human marrow stromal cells following in vitro expansion. Stem Cells 22:675-682.
    • (2004) Stem Cells , vol.22 , pp. 675-682
    • Baxter, M.A.1    Wynn, R.F.2    Jowitt, S.N.3    Wraith, J.E.4    Fairbairn, L.J.5    Bellantuono, I.6
  • 5
    • 34848863384 scopus 로고    scopus 로고
    • Adult mesenchymal stem cells for tissue engineering versus regenerative medicine
    • Caplan AI. 2007. Adult mesenchymal stem cells for tissue engineering versus regenerative medicine. J Cell Physiol 213:341-347.
    • (2007) J Cell Physiol , vol.213 , pp. 341-347
    • Caplan, A.I.1
  • 6
    • 51849111566 scopus 로고    scopus 로고
    • Fibroblast growth factor-2 and -4 promote the proliferation of bone marrowmesenchymal stem cells by the activation of the PI3K-Akt and ERK1/2 signaling pathways
    • Choi SC, Kim SJ, Choi JH, Park CY, Shim WJ, Lim DS. 2008. Fibroblast growth factor-2 and -4 promote the proliferation of bone marrowmesenchymal stem cells by the activation of the PI3K-Akt and ERK1/2 signaling pathways. Stem Cells Dev 17:725-736.
    • (2008) Stem Cells Dev , vol.17 , pp. 725-736
    • Choi, S.C.1    Kim, S.J.2    Choi, J.H.3    Park, C.Y.4    Shim, W.J.5    Lim, D.S.6
  • 7
    • 0034907875 scopus 로고    scopus 로고
    • Modeling pO(2) distributions in the bone marrow hematopoietic compartment. II. Modified Kroghian models
    • Chow DC, Wenning LA, Miller WM, Papoutsakis ET. 2001. Modeling pO(2) distributions in the bone marrow hematopoietic compartment. II. Modified Kroghian models. Biophys J 81:685-696.
    • (2001) Biophys J , vol.81 , pp. 685-696
    • Chow, D.C.1    Wenning, L.A.2    Miller, W.M.3    Papoutsakis, E.T.4
  • 8
    • 0034934262 scopus 로고    scopus 로고
    • Identification of a subpopulation of rapidly self-renewing and multipotential adult stem cells in colonies of human marrow stromal cells
    • Colter DC, Sekiya I, Prockop DJ. 2001. Identification of a subpopulation of rapidly self-renewing and multipotential adult stem cells in colonies of human marrow stromal cells. Proc Natl Acad Sci USA 98:7841-7845.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 7841-7845
    • Colter, D.C.1    Sekiya, I.2    Prockop, D.J.3
  • 11
    • 33845952788 scopus 로고    scopus 로고
    • Effects of glutamine, glucose, and oxygen concentration on the metabolism and proliferation of rabbit adipose-derived stem cells
    • Follmar KE, Decroos FC, Prichard HL, Wang HT, Erdmann D, Olbrich KC. 2006. Effects of glutamine, glucose, and oxygen concentration on the metabolism and proliferation of rabbit adipose-derived stem cells. Tissue Eng 12:3525-3533.
    • (2006) Tissue Eng , vol.12 , pp. 3525-3533
    • Follmar, K.E.1    Decroos, F.C.2    Prichard, H.L.3    Wang, H.T.4    Erdmann, D.5    Olbrich, K.C.6
  • 13
    • 31744442047 scopus 로고    scopus 로고
    • Effects of hypoxia on human mesenchymal stem cell expansion and plasticity in 3D constructs
    • Grayson WL, Zhao F, Izadpanah R, Bunnell B, Ma T. 2006. Effects of hypoxia on human mesenchymal stem cell expansion and plasticity in 3D constructs. J Cell Physiol 207:331-339.
    • (2006) J Cell Physiol , vol.207 , pp. 331-339
    • Grayson, W.L.1    Zhao, F.2    Izadpanah, R.3    Bunnell, B.4    Ma, T.5
  • 14
    • 34249113091 scopus 로고    scopus 로고
    • Hypoxia enhances proliferation and tissue formation of human mesenchymal stem cells
    • Grayson WL, Zhao F, Bunnell B, Ma T. 2007. Hypoxia enhances proliferation and tissue formation of human mesenchymal stem cells. Biochem Biophys Res Commun 358:948-953.
    • (2007) Biochem Biophys Res Commun , vol.358 , pp. 948-953
    • Grayson, W.L.1    Zhao, F.2    Bunnell, B.3    Ma, T.4
  • 15
    • 0042346318 scopus 로고    scopus 로고
    • The Wnt signaling inhibitor dickkopf-1 is required for reentry into the cell cycle of human adult stem cells from bone marrow
    • Gregory CA, Singh H, Perry AS, Prockop DJ. 2003. The Wnt signaling inhibitor dickkopf-1 is required for reentry into the cell cycle of human adult stem cells from bone marrow. J Biol Chem 278:28067-28078.
    • (2003) J Biol Chem , vol.278 , pp. 28067-28078
    • Gregory, C.A.1    Singh, H.2    Perry, A.S.3    Prockop, D.J.4
  • 17
    • 43049176324 scopus 로고    scopus 로고
    • Immunosuppression by mesenchymal stromal cells: From culture to clinic
    • Jones BJ, McTaggart SJ. 2008. Immunosuppression by mesenchymal stromal cells: From culture to clinic. Exp Hematol 36:733-741.
    • (2008) Exp Hematol , vol.36 , pp. 733-741
    • Jones, B.J.1    McTaggart, S.J.2
  • 20
    • 53049108615 scopus 로고    scopus 로고
    • The systematic production of cells for cell therapies
    • Kirouac DC, Zandstra PW. 2008. The systematic production of cells for cell therapies. Cell Stem Cell 3:369-381.
    • (2008) Cell Stem Cell , vol.3 , pp. 369-381
    • Kirouac, D.C.1    Zandstra, P.W.2
  • 21
    • 35448996504 scopus 로고    scopus 로고
    • Immunomodulation by mesenchymal stem cells and clinical experience
    • Le Blanc K, Ringden O. 2007. Immunomodulation by mesenchymal stem cells and clinical experience. J Intern Med 262:509-525.
    • (2007) J Intern Med , vol.262 , pp. 509-525
    • Le Blanc, K.1    Ringden, O.2
  • 22
    • 0030049769 scopus 로고    scopus 로고
    • Comparative analysis of glucose and glutamine metabolism in transformed mammalian cell lines, insect and primary liver cells
    • Neermann J, Wagner R. 1996. Comparative analysis of glucose and glutamine metabolism in transformed mammalian cell lines, insect and primary liver cells. J Cell Physiol 166:152-169.
    • (1996) J Cell Physiol , vol.166 , pp. 152-169
    • Neermann, J.1    Wagner, R.2
  • 23
    • 0342547017 scopus 로고    scopus 로고
    • Real-time monitoring and control of glucose and lactate concentrations in a mammalian cell perfusion reactor
    • Ozturk SS, Thrift JC, Blackie JD,Naveh D. 1997. Real-time monitoring and control of glucose and lactate concentrations in a mammalian cell perfusion reactor. Biotechnol Bioeng 53:372-378.
    • (1997) Biotechnol Bioeng , vol.53 , pp. 372-378
    • Ozturk, S.S.1    Thrift, J.C.2    Blackie, J.D.3    Naveh, D.4
  • 24
    • 8744233676 scopus 로고    scopus 로고
    • Differential effects of equiaxial and uniaxial strain on mesenchymal stem cells
    • Park JS, Chu JS, Cheng C, Chen F, Chen D, Li S. 2004. Differential effects of equiaxial and uniaxial strain on mesenchymal stem cells. Biotechnol Bioeng 88: 359-368.
    • (2004) Biotechnol Bioeng , vol.88 , pp. 359-368
    • Park, J.S.1    Chu, J.S.2    Cheng, C.3    Chen, F.4    Chen, D.5    Li, S.6
  • 25
    • 34250870604 scopus 로고    scopus 로고
    • Prolonged hypoxia concomitant with serum deprivation induces massive human mesenchymal stem cell death
    • Potier E, Ferreira E, Meunier A, Sedel L, Logeart-Avramoglou D, Petite H. 2007. Prolonged hypoxia concomitant with serum deprivation induces massive human mesenchymal stem cell death. Tissue Eng 13:1325-1331.
    • (2007) Tissue Eng , vol.13 , pp. 1325-1331
    • Potier, E.1    Ferreira, E.2    Meunier, A.3    Sedel, L.4    Logeart-Avramoglou, D.5    Petite, H.6
  • 27
    • 33744913533 scopus 로고    scopus 로고
    • Mesenchymal stem cells for treatment of therapy-resistant graft-versus-host disease. Transplantation 81:1390-1397.
    • Mesenchymal stem cells for treatment of therapy-resistant graft-versus-host disease. Transplantation 81:1390-1397.
  • 28
    • 55049084643 scopus 로고    scopus 로고
    • Hypoxic preconditioning results in increased motility and improved therapeutic potential of human mesenchymal stem cells
    • Rosova I, Dao M, Capoccia B, Link D, Nolta JA. 2008. Hypoxic preconditioning results in increased motility and improved therapeutic potential of human mesenchymal stem cells. Stem Cells 26:2173-2182.
    • (2008) Stem Cells , vol.26 , pp. 2173-2182
    • Rosova, I.1    Dao, M.2    Capoccia, B.3    Link, D.4    Nolta, J.A.5
  • 30
    • 33745266607 scopus 로고    scopus 로고
    • Characterization of the optimal culture conditions for clinical scale production of human mesenchymal stem cells
    • Sotiropoulou PA, Perez SA, Salagianni M, Baxevanis CN, Papamichail M. 2006. Characterization of the optimal culture conditions for clinical scale production of human mesenchymal stem cells. Stem Cells 24:462-471.
    • (2006) Stem Cells , vol.24 , pp. 462-471
    • Sotiropoulou, P.A.1    Perez, S.A.2    Salagianni, M.3    Baxevanis, C.N.4    Papamichail, M.5
  • 31
    • 0347627149 scopus 로고    scopus 로고
    • Aging is associated with decreased maximal life span and accelerated senescence of bone marrow stromal cells
    • Stenderup K, Justesen J, Clausen C, Kassem M. 2003. Aging is associated with decreased maximal life span and accelerated senescence of bone marrow stromal cells. Bone 33:919-926.
    • (2003) Bone , vol.33 , pp. 919-926
    • Stenderup, K.1    Justesen, J.2    Clausen, C.3    Kassem, M.4
  • 32
    • 34249290435 scopus 로고    scopus 로고
    • Mesenchymal stem cells for treating GVHD: In vivo fate and optimal dose
    • Subbanna PK. 2007. Mesenchymal stem cells for treating GVHD: In vivo fate and optimal dose. Med Hypotheses 69:469-470.
    • (2007) Med Hypotheses , vol.69 , pp. 469-470
    • Subbanna, P.K.1
  • 33
    • 33745668430 scopus 로고    scopus 로고
    • Mesenchymal stem cells for tissue engineering and regenerative medicine
    • Tae SK, Lee SH, Park JS, Im GI. 2006. Mesenchymal stem cells for tissue engineering and regenerative medicine. Biomed Mater 1:63-71.
    • (2006) Biomed Mater , vol.1 , pp. 63-71
    • Tae, S.K.1    Lee, S.H.2    Park, J.S.3    Im, G.I.4
  • 34
    • 66249108601 scopus 로고    scopus 로고
    • Understanding the Warburg effect: The metabolic requirements of cell proliferation
    • Vander Heiden, MG, Cantley LC, Thompson CB. 2009. Understanding the Warburg effect: The metabolic requirements of cell proliferation. Science 324:1029-1033.
    • (2009) Science , vol.324 , pp. 1029-1033
    • Vander Heiden, M.G.1    Cantley, L.C.2    Thompson, C.B.3
  • 35
    • 20144385673 scopus 로고    scopus 로고
    • Influence of oxygen on the proliferation and metabolism of adipose derived adult stem cells
    • Wang DW, Fermor B, Gimble JM, Awad HA, Guilak F. 2005. Influence of oxygen on the proliferation and metabolism of adipose derived adult stem cells. J Cell Physiol 204:184-191.
    • (2005) J Cell Physiol , vol.204 , pp. 184-191
    • Wang, D.W.1    Fermor, B.2    Gimble, J.M.3    Awad, H.A.4    Guilak, F.5
  • 36
    • 33745954928 scopus 로고    scopus 로고
    • Hypoxia and serum deprivation-induced apoptosis in mesenchymal stem cells
    • Zhu W, Chen J, Cong X, Hu S, Chen X. 2006. Hypoxia and serum deprivation-induced apoptosis in mesenchymal stem cells. Stem Cells 24:416-425.
    • (2006) Stem Cells , vol.24 , pp. 416-425
    • Zhu, W.1    Chen, J.2    Cong, X.3    Hu, S.4    Chen, X.5


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