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Volumn 586, Issue 18, 2012, Pages 2835-2840

The multiple and enigmatic roles of guanylyl cyclase C in intestinal homeostasis

Author keywords

CGMP; Guanylyl cyclase C; Intestine

Indexed keywords

CYCLIC GMP; ENTEROTOXIN; GUANYLATE CYCLASE; GUANYLATE CYCLASE C; GUANYLIN; UNCLASSIFIED DRUG; UROGUANYLIN;

EID: 84864930278     PISSN: 00145793     EISSN: 18733468     Source Type: Journal    
DOI: 10.1016/j.febslet.2012.07.028     Document Type: Conference Paper
Times cited : (68)

References (63)
  • 2
    • 0024710202 scopus 로고
    • The role of saliva in maintaining oral homeostasis
    • I.D. Mandel The role of saliva in maintaining oral homeostasis J. Am. Dent. Assoc. 119 1989 298 304
    • (1989) J. Am. Dent. Assoc. , vol.119 , pp. 298-304
    • Mandel, I.D.1
  • 3
    • 83655191565 scopus 로고    scopus 로고
    • Epithelial barrier: An interface for the cross-communication between gut flora and immune system
    • Y. Goto, and H. Kiyono Epithelial barrier: an interface for the cross-communication between gut flora and immune system Immunol. Rev. 245 2012 147 163
    • (2012) Immunol. Rev. , vol.245 , pp. 147-163
    • Goto, Y.1    Kiyono, H.2
  • 4
    • 84864959123 scopus 로고    scopus 로고
    • Intestinal Morphology, Intestinal Regeneration and the Promise of Tissue Engineering
    • A.N. Langnas, E.M.M. Quigley, K.A. Tappenden, Blackwell Publishing Ltd Oxford, UK
    • D.A.J. Lloyd, and S.M. Gabe Intestinal Morphology, Intestinal Regeneration and the Promise of Tissue Engineering A.N. Langnas, E.M.M. Quigley, K.A. Tappenden, Intestinal Failure: Diagnosis, Management and Transplantation 2009 Blackwell Publishing Ltd Oxford, UK 11 19
    • (2009) Intestinal Failure: Diagnosis, Management and Transplantation , pp. 11-19
    • Lloyd, D.A.J.1    Gabe, S.M.2
  • 5
    • 40749093245 scopus 로고    scopus 로고
    • New ways of thinking about (and teaching about) intestinal epithelial function
    • K.E. Barrett New ways of thinking about (and teaching about) intestinal epithelial function Adv. Physiol. Educ. 32 2008 25 34
    • (2008) Adv. Physiol. Educ. , vol.32 , pp. 25-34
    • Barrett, K.E.1
  • 6
    • 77957223906 scopus 로고    scopus 로고
    • Intestinal crypt homeostasis results from neutral competition between symmetrically dividing Lgr5 stem cells
    • H.J. Snippert Intestinal crypt homeostasis results from neutral competition between symmetrically dividing Lgr5 stem cells Cell 143 2010 134 144
    • (2010) Cell , vol.143 , pp. 134-144
    • Snippert, H.J.1
  • 7
    • 76149088435 scopus 로고    scopus 로고
    • The incidence, intensity and host morbidity of human parasitic protozoan infections in gastrointestinal disorder outpatients in Buea sub division, cameroon
    • J.V. Mbuh, H.N. Ntonifor, and J.T. Ojong The incidence, intensity and host morbidity of human parasitic protozoan infections in gastrointestinal disorder outpatients in Buea sub division, cameroon J. Infect. Dev. Ctries. 4 2010 38 43
    • (2010) J. Infect. Dev. Ctries. , vol.4 , pp. 38-43
    • Mbuh, J.V.1    Ntonifor, H.N.2    Ojong, J.T.3
  • 8
    • 77949396850 scopus 로고    scopus 로고
    • Yeasts in the gut: From commensals to infectious agents
    • J. Schulze, and U. Sonnenborn Yeasts in the gut: from commensals to infectious agents Dtsch. Arztebl. Int. 106 2009 837 842
    • (2009) Dtsch. Arztebl. Int. , vol.106 , pp. 837-842
    • Schulze, J.1    Sonnenborn, U.2
  • 11
    • 77954821992 scopus 로고    scopus 로고
    • Infectious diarrhea: Cellular and molecular mechanisms
    • K. Hodges, and R. Gill Infectious diarrhea: cellular and molecular mechanisms Gut. Microbes 1 2010 4 21
    • (2010) Gut. Microbes , vol.1 , pp. 4-21
    • Hodges, K.1    Gill, R.2
  • 12
    • 0037226740 scopus 로고    scopus 로고
    • Diarrhea and malnutrition
    • K.H. Brown Diarrhea and malnutrition J. Nutr. 133 2003 328S 332S
    • (2003) J. Nutr. , vol.133
    • Brown, K.H.1
  • 13
    • 0011155218 scopus 로고
    • Heat-stable enterotoxin of Escherichia coli: In vitro effects on guanylate cyclase activity, cyclic GMP concentration, and ion transport in small intestine
    • M. Field, L.H. Graf Jr., W.J. Laird, and P.L. Smith Heat-stable enterotoxin of Escherichia coli: in vitro effects on guanylate cyclase activity, cyclic GMP concentration, and ion transport in small intestine Proc. Natl. Acad. Sci. U.S.A. 75 1978 2800 2804
    • (1978) Proc. Natl. Acad. Sci. U.S.A. , vol.75 , pp. 2800-2804
    • Field, M.1    Graf, Jr.L.H.2    Laird, W.J.3    Smith, P.L.4
  • 14
    • 84860125964 scopus 로고    scopus 로고
    • Familial diarrhea syndrome caused by an activating GUCY2C mutation
    • T. Fiskerstrand Familial diarrhea syndrome caused by an activating GUCY2C mutation N. Engl. J. Med. 366 2012 1586 1595
    • (2012) N. Engl. J. Med. , vol.366 , pp. 1586-1595
    • Fiskerstrand, T.1
  • 15
    • 84860715301 scopus 로고    scopus 로고
    • Meconium ileus caused by mutations in GUCY2C, encoding the CFTR-activating guanylate cyclase 2C
    • H. Romi Meconium ileus caused by mutations in GUCY2C, encoding the CFTR-activating guanylate cyclase 2C Am. J. Hum. Genet. 90 2012 893 899
    • (2012) Am. J. Hum. Genet. , vol.90 , pp. 893-899
    • Romi, H.1
  • 16
    • 75049084644 scopus 로고    scopus 로고
    • Receptor guanylyl cyclase C (GC-C): Regulation and signal transduction
    • N. Basu, N. Arshad, and S.S. Visweswariah Receptor guanylyl cyclase C (GC-C): regulation and signal transduction Mol. Cell. Biochem. 334 2010 67 80
    • (2010) Mol. Cell. Biochem. , vol.334 , pp. 67-80
    • Basu, N.1    Arshad, N.2    Visweswariah, S.S.3
  • 17
    • 79952079101 scopus 로고    scopus 로고
    • Toxin mediated diarrhea in the 21 century: The pathophysiology of intestinal ion transport in the course of ETEC, V. cholerae and rotavirus infection
    • S. Kopic, and J.P. Geibel Toxin mediated diarrhea in the 21 century: the pathophysiology of intestinal ion transport in the course of ETEC, V. cholerae and rotavirus infection. Toxins (Basel) 2 2010 2132 2157
    • (2010) Toxins (Basel) , vol.2 , pp. 2132-2157
    • Kopic, S.1    Geibel, J.P.2
  • 19
    • 0025647794 scopus 로고
    • Guanylyl cyclase is a heat-stable enterotoxin receptor
    • S. Schulz, C.K. Green, P.S. Yuen, and D.L. Garbers Guanylyl cyclase is a heat-stable enterotoxin receptor Cell 63 1990 941 948
    • (1990) Cell , vol.63 , pp. 941-948
    • Schulz, S.1    Green, C.K.2    Yuen, P.S.3    Garbers, D.L.4
  • 20
    • 84874201626 scopus 로고    scopus 로고
    • Defying the stereotype: Non-canonical roles of the Peptide hormones guanylin and uroguanylin
    • N. Basu, and S.S. Visweswariah Defying the stereotype: non-canonical roles of the Peptide hormones guanylin and uroguanylin Front. Endocrinol. (Lausanne) 2 2011 14
    • (2011) Front. Endocrinol. (Lausanne) , vol.2 , pp. 14
    • Basu, N.1    Visweswariah, S.S.2
  • 21
    • 0027497098 scopus 로고
    • Uroguanylin: Structure and activity of a second endogenous peptide that stimulates intestinal guanylate cyclase
    • F.K. Hamra Uroguanylin: structure and activity of a second endogenous peptide that stimulates intestinal guanylate cyclase Proc. Natl. Acad. Sci. U.S.A. 90 1993 10464 10468
    • (1993) Proc. Natl. Acad. Sci. U.S.A. , vol.90 , pp. 10464-10468
    • Hamra, F.K.1
  • 22
    • 0029058814 scopus 로고
    • Guanylin: A peptide regulator of epithelial transport
    • L.R. Forte, and M.G. Currie Guanylin: a peptide regulator of epithelial transport FASEB J. 9 1995 643 650
    • (1995) FASEB J. , vol.9 , pp. 643-650
    • Forte, L.R.1    Currie, M.G.2
  • 23
    • 13144251141 scopus 로고    scopus 로고
    • Membrane targeting of cGMP-dependent protein kinase is required for cystic fibrosis transmembrane conductance regulator Cl- channel activation
    • A.B. Vaandrager Membrane targeting of cGMP-dependent protein kinase is required for cystic fibrosis transmembrane conductance regulator Cl- channel activation Proc. Natl. Acad. Sci. U.S.A. 95 1998 1466 1471
    • (1998) Proc. Natl. Acad. Sci. U.S.A. , vol.95 , pp. 1466-1471
    • Vaandrager, A.B.1
  • 24
    • 0033976962 scopus 로고    scopus 로고
    • Differential role of cyclic GMP-dependent protein kinase II in ion transport in murine small intestine and colon
    • A.B. Vaandrager, A.G. Bot, P. Ruth, A. Pfeifer, F. Hofmann, and H.R. De Jonge Differential role of cyclic GMP-dependent protein kinase II in ion transport in murine small intestine and colon Gastroenterology 118 2000 108 114
    • (2000) Gastroenterology , vol.118 , pp. 108-114
    • Vaandrager, A.B.1    Bot, A.G.2    Ruth, P.3    Pfeifer, A.4    Hofmann, F.5    De Jonge, H.R.6
  • 25
    • 20444441935 scopus 로고    scopus 로고
    • + antiporter 3 (NHE3) requires PDZ domain adapter NHERF2, a broad specificity protein kinase G-anchoring protein
    • + antiporter 3 (NHE3) requires PDZ domain adapter NHERF2, a broad specificity protein kinase G-anchoring protein J. Biol. Chem. 280 2005 16642 16650
    • (2005) J. Biol. Chem. , vol.280 , pp. 16642-16650
    • Cha, B.1
  • 26
    • 15244346301 scopus 로고    scopus 로고
    • Heat-stable enterotoxin of Escherichia coli stimulates a non-CFTR-mediated duodenal bicarbonate secretory pathway
    • Z.M. Sellers Heat-stable enterotoxin of Escherichia coli stimulates a non-CFTR-mediated duodenal bicarbonate secretory pathway Am. J. Physiol. Gastrointest. Liver Physiol. 288 2005 G654 G663
    • (2005) Am. J. Physiol. Gastrointest. Liver Physiol. , vol.288
    • Sellers, Z.M.1
  • 27
    • 49649106115 scopus 로고    scopus 로고
    • Enterotoxin preconditioning restores calcium-sensing receptor-mediated cytostasis in colon cancer cells
    • G.M. Pitari, J.E. Lin, F.J. Shah, W.J. Lubbe, D.S. Zuzga, P. Li, S. Schulz, and S.A. Waldman Enterotoxin preconditioning restores calcium-sensing receptor-mediated cytostasis in colon cancer cells Carcinogenesis 29 2008 1601 1607
    • (2008) Carcinogenesis , vol.29 , pp. 1601-1607
    • Pitari, G.M.1    Lin, J.E.2    Shah, F.J.3    Lubbe, W.J.4    Zuzga, D.S.5    Li, P.6    Schulz, S.7    Waldman, S.A.8
  • 28
    • 0027325290 scopus 로고
    • Guanylin stimulation of Cl- secretion in human intestinal T84 cells via cyclic guanosine monophosphate
    • L.R. Forte, S.L. Eber, J.T. Turner, R.H. Freeman, K.F. Fok, and M.G. Currie Guanylin stimulation of Cl- secretion in human intestinal T84 cells via cyclic guanosine monophosphate J. Clin. Invest. 91 1993 2423 2428
    • (1993) J. Clin. Invest. , vol.91 , pp. 2423-2428
    • Forte, L.R.1    Eber, S.L.2    Turner, J.T.3    Freeman, R.H.4    Fok, K.F.5    Currie, M.G.6
  • 29
    • 78049283798 scopus 로고    scopus 로고
    • Linaclotide, through activation of guanylate cyclase C, acts locally in the gastrointestinal tract to elicit enhanced intestinal secretion and transit
    • R.W. Busby Linaclotide, through activation of guanylate cyclase C, acts locally in the gastrointestinal tract to elicit enhanced intestinal secretion and transit Eur. J. Pharmacol. 649 2010 328 335
    • (2010) Eur. J. Pharmacol. , vol.649 , pp. 328-335
    • Busby, R.W.1
  • 30
    • 80051640525 scopus 로고    scopus 로고
    • Two randomized trials of linaclotide for chronic constipation
    • A.J. Lembo Two randomized trials of linaclotide for chronic constipation N. Engl. J. Med. 365 2011 527 536
    • (2011) N. Engl. J. Med. , vol.365 , pp. 527-536
    • Lembo, A.J.1
  • 31
    • 0031581108 scopus 로고    scopus 로고
    • Mice lacking the guanylyl cyclase C receptor are resistant to STa-induced intestinal secretion
    • E.A. Mann, M.L. Jump, J. Wu, E. Yee, and R.A. Giannella Mice lacking the guanylyl cyclase C receptor are resistant to STa-induced intestinal secretion Biochem. Biophys. Res. Commun. 239 1997 463 466
    • (1997) Biochem. Biophys. Res. Commun. , vol.239 , pp. 463-466
    • Mann, E.A.1    Jump, M.L.2    Wu, J.3    Yee, E.4    Giannella, R.A.5
  • 32
    • 0030779011 scopus 로고    scopus 로고
    • Disruption of the guanylyl cyclase-C gene leads to a paradoxical phenotype of viable but heat-stable enterotoxin-resistant mice
    • S. Schulz, M.J. Lopez, M. Kuhn, and D.L. Garbers Disruption of the guanylyl cyclase-C gene leads to a paradoxical phenotype of viable but heat-stable enterotoxin-resistant mice J. Clin. Invest. 100 1997 1590 1595
    • (1997) J. Clin. Invest. , vol.100 , pp. 1590-1595
    • Schulz, S.1    Lopez, M.J.2    Kuhn, M.3    Garbers, D.L.4
  • 33
    • 80052362732 scopus 로고    scopus 로고
    • A uroguanylin-GUCY2C endocrine axis regulates feeding in mice
    • M.A. Valentino A uroguanylin-GUCY2C endocrine axis regulates feeding in mice J. Clin. Invest. 121 2011 3578 3588
    • (2011) J. Clin. Invest. , vol.121 , pp. 3578-3588
    • Valentino, M.A.1
  • 34
    • 7044269199 scopus 로고    scopus 로고
    • Uroguanylin and guanylin peptides: Pharmacology and experimental therapeutics
    • L.R. Forte Jr. Uroguanylin and guanylin peptides: pharmacology and experimental therapeutics Pharmacol. Ther. 104 2004 137 162
    • (2004) Pharmacol. Ther. , vol.104 , pp. 137-162
    • Forte, Jr.L.R.1
  • 35
    • 81155159830 scopus 로고    scopus 로고
    • Role for the membrane receptor guanylyl cyclase-C in attention deficiency and hyperactive behavior
    • R. Gong Role for the membrane receptor guanylyl cyclase-C in attention deficiency and hyperactive behavior Science 333 2011 1642 1646
    • (2011) Science , vol.333 , pp. 1642-1646
    • Gong, R.1
  • 36
    • 1842841890 scopus 로고    scopus 로고
    • Expression of the receptor guanylyl cyclase C and its ligands in reproductive tissues of the rat: A potential role for a novel signaling pathway in the epididymis
    • M. Jaleel, R.M. London, S.L. Eber, L.R. Forte, and S.S. Visweswariah Expression of the receptor guanylyl cyclase C and its ligands in reproductive tissues of the rat: a potential role for a novel signaling pathway in the epididymis Biol. Reprod. 67 2002 1975 1980
    • (2002) Biol. Reprod. , vol.67 , pp. 1975-1980
    • Jaleel, M.1    London, R.M.2    Eber, S.L.3    Forte, L.R.4    Visweswariah, S.S.5
  • 37
    • 0345701291 scopus 로고    scopus 로고
    • Bacterial enterotoxins are associated with resistance to colon cancer
    • G.M. Pitari Bacterial enterotoxins are associated with resistance to colon cancer Proc. Natl. Acad. Sci. U.S.A. 100 2003 2695 2699
    • (2003) Proc. Natl. Acad. Sci. U.S.A. , vol.100 , pp. 2695-2699
    • Pitari, G.M.1
  • 38
    • 0034933794 scopus 로고    scopus 로고
    • Guanylyl cyclase C agonists regulate progression through the cell cycle of human colon carcinoma cells
    • G.M. Pitari, M.D. Di Guglielmo, J. Park, S. Schulz, and S.A. Waldman Guanylyl cyclase C agonists regulate progression through the cell cycle of human colon carcinoma cells Proc. Natl. Acad. Sci. U.S.A. 98 2001 7846 7851
    • (2001) Proc. Natl. Acad. Sci. U.S.A. , vol.98 , pp. 7846-7851
    • Pitari, G.M.1    Di Guglielmo, M.D.2    Park, J.3    Schulz, S.4    Waldman, S.A.5
  • 39
    • 72249093342 scopus 로고    scopus 로고
    • The hormone receptor GUCY2C suppresses intestinal tumor formation by inhibiting AKT signaling
    • J.E. Lin The hormone receptor GUCY2C suppresses intestinal tumor formation by inhibiting AKT signaling Gastroenterology 138 2010 241 254
    • (2010) Gastroenterology , vol.138 , pp. 241-254
    • Lin, J.E.1
  • 40
    • 23944496417 scopus 로고    scopus 로고
    • Proliferative signaling by store-operated calcium channels opposes colon cancer cell cytostasis induced by bacterial enterotoxins
    • S. Kazerounian Proliferative signaling by store-operated calcium channels opposes colon cancer cell cytostasis induced by bacterial enterotoxins J. Pharmacol. Exp. Ther. 314 2005 1013 1022
    • (2005) J. Pharmacol. Exp. Ther. , vol.314 , pp. 1013-1022
    • Kazerounian, S.1
  • 41
    • 28244432560 scopus 로고    scopus 로고
    • Interruption of homologous desensitization in cyclic guanosine 3′,5′-monophosphate signaling restores colon cancer cytostasis by bacterial enterotoxins
    • G.M. Pitari, R.I. Baksh, D.M. Harris, P. Li, S. Kazerounian, and S.A. Waldman Interruption of homologous desensitization in cyclic guanosine 3′,5′-monophosphate signaling restores colon cancer cytostasis by bacterial enterotoxins Cancer Res. 65 2005 11129 11135
    • (2005) Cancer Res. , vol.65 , pp. 11129-11135
    • Pitari, G.M.1    Baksh, R.I.2    Harris, D.M.3    Li, P.4    Kazerounian, S.5    Waldman, S.A.6
  • 44
    • 33847644982 scopus 로고    scopus 로고
    • The novel functions of cGMP-specific phosphodiesterase 5 and its inhibitors in carcinoma cells and pulmonary/cardiovascular vessels
    • B. Zhu, and S.J. Strada The novel functions of cGMP-specific phosphodiesterase 5 and its inhibitors in carcinoma cells and pulmonary/cardiovascular vessels Curr. Top. Med. Chem. 7 2007 437 454
    • (2007) Curr. Top. Med. Chem. , vol.7 , pp. 437-454
    • Zhu, B.1    Strada, S.J.2
  • 46
    • 70349306462 scopus 로고    scopus 로고
    • Cross talk between receptor guanylyl cyclase C and c-src tyrosine kinase regulates colon cancer cell cytostasis
    • N. Basu, R. Bhandari, V.T. Natarajan, and S.S. Visweswariah Cross talk between receptor guanylyl cyclase C and c-src tyrosine kinase regulates colon cancer cell cytostasis Mol. Cell. Biol. 29 2009 5277 5289
    • (2009) Mol. Cell. Biol. , vol.29 , pp. 5277-5289
    • Basu, N.1    Bhandari, R.2    Natarajan, V.T.3    Visweswariah, S.S.4
  • 47
    • 65949102791 scopus 로고    scopus 로고
    • Synergistic activity of the SRC family kinase inhibitor dasatinib and oxaliplatin in colon carcinoma cells is mediated by oxidative stress
    • S. Kopetz Synergistic activity of the SRC family kinase inhibitor dasatinib and oxaliplatin in colon carcinoma cells is mediated by oxidative stress Cancer Res. 69 2009 3842 3849
    • (2009) Cancer Res. , vol.69 , pp. 3842-3849
    • Kopetz, S.1
  • 48
    • 70949107842 scopus 로고    scopus 로고
    • Inflammatory bowel disease
    • C. Abraham, and J.H. Cho Inflammatory bowel disease N. Eng. J. Med. 361 2009 2066 2078
    • (2009) N. Eng. J. Med. , vol.361 , pp. 2066-2078
    • Abraham, C.1    Cho, J.H.2
  • 49
    • 74049102306 scopus 로고    scopus 로고
    • Review article: The clinical management of congenital chloride diarrhoea
    • S. Wedenoja, P. Hoglund, and C. Holmberg Review article: the clinical management of congenital chloride diarrhoea Aliment. Pharmacol. Ther. 31 2010 477 485
    • (2010) Aliment. Pharmacol. Ther. , vol.31 , pp. 477-485
    • Wedenoja, S.1    Hoglund, P.2    Holmberg, C.3
  • 50
    • 66449131072 scopus 로고    scopus 로고
    • Downregulation of sodium transporters and NHERF proteins in IBD patients and mouse colitis models: Potential contributors to IBD-associated diarrhea
    • S. Sullivan Downregulation of sodium transporters and NHERF proteins in IBD patients and mouse colitis models: potential contributors to IBD-associated diarrhea Inflamm. Bowel Dis. 15 2009 261 274
    • (2009) Inflamm. Bowel Dis. , vol.15 , pp. 261-274
    • Sullivan, S.1
  • 51
    • 69249100598 scopus 로고    scopus 로고
    • Changes in mucosal homeostasis predispose NHE3 knockout mice to increased susceptibility to DSS-induced epithelial injury
    • 965975 975 e1-975 e 10
    • P.R. Kiela Changes in mucosal homeostasis predispose NHE3 knockout mice to increased susceptibility to DSS-induced epithelial injury Gastroenterology 137 965-975 2009 975 e1-975 e 10
    • (2009) Gastroenterology , vol.137
    • Kiela, P.R.1
  • 54
    • 34547621585 scopus 로고    scopus 로고
    • Genome-wide gene expression differences in Crohn's disease and ulcerative colitis from endoscopic pinch biopsies: Insights into distinctive pathogenesis
    • F. Wu Genome-wide gene expression differences in Crohn's disease and ulcerative colitis from endoscopic pinch biopsies: insights into distinctive pathogenesis Inflamm. Bowel Dis. 13 2007 807 821
    • (2007) Inflamm. Bowel Dis. , vol.13 , pp. 807-821
    • Wu, F.1
  • 55
    • 79959271087 scopus 로고    scopus 로고
    • Intestinal homeostasis and its breakdown in inflammatory bowel disease
    • K.J. Maloy, and F. Powrie Intestinal homeostasis and its breakdown in inflammatory bowel disease Nature 474 2011 298 306
    • (2011) Nature , vol.474 , pp. 298-306
    • Maloy, K.J.1    Powrie, F.2
  • 57
    • 1342303482 scopus 로고    scopus 로고
    • Of mice and not men: Differences between mouse and human immunology
    • J. Mestas, and C.C. Hughes Of mice and not men: differences between mouse and human immunology J. Immunol. 172 2004 2731 2738
    • (2004) J. Immunol. , vol.172 , pp. 2731-2738
    • Mestas, J.1    Hughes, C.C.2
  • 58
    • 0030452310 scopus 로고    scopus 로고
    • Intestinal secretory defects and dwarfism in mice lacking cGMP-dependent protein kinase II
    • A. Pfeifer, A. Aszodi, U. Seidler, P. Ruth, F. Hofmann, and R. Fassler Intestinal secretory defects and dwarfism in mice lacking cGMP-dependent protein kinase II Science 274 1996 2082 2086
    • (1996) Science , vol.274 , pp. 2082-2086
    • Pfeifer, A.1    Aszodi, A.2    Seidler, U.3    Ruth, P.4    Hofmann, F.5    Fassler, R.6
  • 59
    • 78650674716 scopus 로고    scopus 로고
    • Cyclic GMP and protein kinase G control a Src-containing mechanosome in osteoblasts
    • Rangaswami, H. et al. (2010). Cyclic GMP and protein kinase G control a Src-containing mechanosome in osteoblasts. Sci. Signal 3, ra91.
    • (2010) Sci. Signal , vol.3
    • Rangaswami, H.1
  • 60
    • 0038371139 scopus 로고    scopus 로고
    • CGMP-dependent protein kinase II modulates mPer1 and mPer2 gene induction and influences phase shifts of the circadian clock
    • H. Oster, C. Werner, M.C. Magnone, H. Mayser, R. Feil, M.W. Seeliger, F. Hofmann, and U. Albrecht CGMP-dependent protein kinase II modulates mPer1 and mPer2 gene induction and influences phase shifts of the circadian clock Curr. Biol. 13 2003 725 733
    • (2003) Curr. Biol. , vol.13 , pp. 725-733
    • Oster, H.1    Werner, C.2    Magnone, M.C.3    Mayser, H.4    Feil, R.5    Seeliger, M.W.6    Hofmann, F.7    Albrecht, U.8
  • 61
    • 0033369604 scopus 로고    scopus 로고
    • Circadian regulation of uroguanylin and guanylin in the rat intestine
    • L.A. Scheving, and W.H. Jin Circadian regulation of uroguanylin and guanylin in the rat intestine Am. J. Physiol. 277 1999 C1177 C1183
    • (1999) Am. J. Physiol. , vol.277
    • Scheving, L.A.1    Jin, W.H.2
  • 62
    • 2542580835 scopus 로고    scopus 로고
    • Glycosylation of the receptor guanylate cyclase C: Role in ligand binding and catalytic activity
    • Y. Ghanekar, A. Chandrashaker, U. Tatu, and S.S. Visweswariah Glycosylation of the receptor guanylate cyclase C: role in ligand binding and catalytic activity Biochem. J. 379 2004 653 663
    • (2004) Biochem. J. , vol.379 , pp. 653-663
    • Ghanekar, Y.1    Chandrashaker, A.2    Tatu, U.3    Visweswariah, S.S.4
  • 63
    • 0141447328 scopus 로고    scopus 로고
    • Cellular refractoriness to the heat-stable enterotoxin peptide is associated with alterations in levels of the differentially glycosylated forms of guanylyl cyclase C
    • Y. Ghanekar, A. Chandrashaker, and S.S. Visweswariah Cellular refractoriness to the heat-stable enterotoxin peptide is associated with alterations in levels of the differentially glycosylated forms of guanylyl cyclase C Eur. J. Biochem. 270 2003 3848 3857
    • (2003) Eur. J. Biochem. , vol.270 , pp. 3848-3857
    • Ghanekar, Y.1    Chandrashaker, A.2    Visweswariah, S.S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.