Community-wide convergent evolution in insect adaptation to toxic cardenolides by substitutions in the Na,K-ATPase

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 32, 2012, Pages 13040-13045

  Dobler, Susanne ^a   Dalla, Safaa ^a   Wagschal, Vera ^a   Agrawal, Anurag A ^b  

^a UNIVERSITY OF HAMBURG   (Germany)

^b Department of Obstetrics Gynecology   (United States)

Author keywords

Cardiac glycosides; Insect plant interactions; Specialist herbivores; Target site insensitivity; Toxin resistance

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); CARDENOLIDE;

ALPHA CHAIN; AMINO ACID SUBSTITUTION; ARTICLE; BEETLE; BUTTERFLY; COLEOPTERA; CONTROLLED STUDY; CONVERGENT EVOLUTION; DROSOPHILA MELANOGASTER; EUKARYOTIC CELL; EVOLUTIONARY ADAPTATION; FLY; GENE CONSTRUCT; GENE SEQUENCE; GENETIC VARIABILITY; HETEROPTERA; INSECT; MOLECULAR EVOLUTION; NONHUMAN; PHYLOGENY; PLANT; PRIORITY JOURNAL;

ADAPTATION, BIOLOGICAL; AMINO ACID SEQUENCE; ANALYSIS OF VARIANCE; ANIMALS; BASE SEQUENCE; CARDENOLIDES; COMPUTATIONAL BIOLOGY; DNA PRIMERS; DRUG RESISTANCE; EVOLUTION, MOLECULAR; INSECTS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTATION, MISSENSE; NORTH AMERICA; PHYLOGENY; SEQUENCE ANALYSIS, DNA; SODIUM-POTASSIUM-EXCHANGING ATPASE; SPECIES SPECIFICITY;

AGROMYZIDAE; CHRYSOCHUS; CHRYSOMELIDAE; COLEOPTERA; DANAUS PLEXIPPUS; DIPTERA; DROSOPHILA MELANOGASTER; EUKARYOTA; HETEROPTERA; HEXAPODA; LABIDOMERA CLIVICOLLIS; LIRIOMYZA ACLEPIADIS; LYGAEIDAE; LYGAEUS KALMII; MAMMALIA; ONCOPELTUS FASCIATUS; STROPHANTHUS GRATUS;

EID: 84864651595     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1202111109     Document Type: Article

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