Extensive random mutagenesis analysis of the Na+/K+-ATPase α subunit identifies knows and previously unidentified amino acid residues that alter ouabain sensitivity: Implications for ouabain binding

European Journal of Biochemistry

Volumn 248, Issue 2, 1997, Pages 488-495

  Croyle, Michelle L ^a   Woo, Alison L ^a   Lingrel, Jerry B ^a  

^a UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

Author keywords

Cardiac glycoside; Drug interaction; Na+ K+ exchaning ATPase; Ouabain; Random mutagenesis

Indexed keywords

ADENOSINE TRIPHOSPHATASE; OUABAIN;

AMINO ACID SUBSTITUTION; ARTICLE; BINDING SITE; ENZYME ACTIVITY; ENZYME SUBUNIT; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; SHEEP;

OVIS ARIES; STROPHANTHUS GRATUS;

EID: 0030961153     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1432-1033.1997.00488.x     Document Type: Article

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