Mediation of cardiac glycoside insensitivity in the monarch butterfly (danaus plexippus): Role of an amino acid substitution in the ouabain binding site of NA+,K + -ATPase

Journal of Chemical Ecology

Volumn 22, Issue 10, 1996, Pages 1921-1937

  Holzinger, F ^a   Wink, M ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

Amino acid substitution; Cardiac glycosides. Na + ,K + ATPase; Danaus gilippus; Danaus plexippus; Gene expression; Insensitivity; Sequestration; Site directed mutation; Syntomeida epilais; Syntomis mogadorensis; Target site modification

Indexed keywords

DANAUS PLEXIPPUS;

EID: 0030446130     PISSN: 00980331     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02028512     Document Type: Article

References (2)

1. ASKEW, G. R., and LINGREL, J. B. 1994. Identification of an amino acid substitution in human Na,K-ATPase which confers differentially reduced affinity for two related cardiac glycosides. J. Biol. Chem. 269:24120-24126.
2. BERNAYS, E. A. and CHAPMAN. R. F. 1994. Host-plant selection by phytophagous insects. Chapman & Hall, New York.