Drosophila larvae lacking the bcl-2 gene, buffy, are sensitive to nutrient stress, maintain increased basal target of rapamycin (Tor) signaling and exhibit characteristics of altered basal energy metabolism

BMC Biology

Volumn 10, Issue , 2012, Pages

  Monserrate, Jessica P ^a   Chen, Michelle Y Y ^a   Brachmann, Carrie B ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Autophagy; Bcl 2; Metabolism; Non apoptotic; Nutrient restriction; S6k; Starvation; Tor

Indexed keywords

ANIMALIA;

ADENOSINE TRIPHOSPHATE; AMINO ACID; BUFFY PROTEIN, DROSOPHILA; DROSOPHILA PROTEIN; GLYCOGEN; LACTIC ACID; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN BCL 2; S6 KINASE; TARGET OF RAPAMYCIN KINASE; TARGET OF RAPAMYCIN PROTEIN, DROSOPHILA;

ADAPTATION; ANIMAL; ARTICLE; AUTOPHAGY; DROSOPHILA MELANOGASTER; ENERGY METABOLISM; ENZYMOLOGY; FAT BODY; FEEDING BEHAVIOR; GENE EXPRESSION REGULATION; GENETICS; LARVA; LIPID METABOLISM; METABOLISM; MUTATION; PHOSPHORYLATION; PHYSIOLOGICAL STRESS; PROTO ONCOGENE; SIGNAL TRANSDUCTION; SURVIVAL; ULTRASTRUCTURE;

ADAPTATION, PHYSIOLOGICAL; ADENOSINE TRIPHOSPHATE; AMINO ACIDS; ANIMALS; AUTOPHAGY; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; ENERGY METABOLISM; FAT BODY; FEEDING BEHAVIOR; GENE EXPRESSION REGULATION; GENES, BCL-2; GLYCOGEN; LACTIC ACID; LARVA; LIPID METABOLISM; MUTATION; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-BCL-2; RIBOSOMAL PROTEIN S6 KINASES; SIGNAL TRANSDUCTION; STRESS, PHYSIOLOGICAL; SURVIVAL ANALYSIS; TOR SERINE-THREONINE KINASES;

EID: 84864615977     PISSN: None     EISSN: 17417007     Source Type: Journal    
DOI: 10.1186/1741-7007-10-63     Document Type: Article

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