-
2
-
-
0032080283
-
Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1
-
Saitoh M, Nishitoh H, Fujii M, Takeda K, Tobiume K, Sawada Y, Kawabata M, Miyazono K, Ichijo H: Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1. EMBO J 1998;17:2596-2606.
-
(1998)
EMBO J.
, Issue.17
, pp. 2596-2606
-
-
Saitoh, M.1
Nishitoh, H.2
Fujii, M.3
Takeda, K.4
Tobiume, K.5
Sawada, Y.6
Kawabata, M.7
Miyazono, K.8
Ichijo, H.9
-
3
-
-
0032504189
-
Reactive oxygen species- and dimerizationinduced activation of apoptosis signal-regulating kinase 1 in tumor necrosis factor-alpha signal transduction
-
Gotoh Y, Cooper JA: Reactive oxygen species- and dimerizationinduced activation of apoptosis signal-regulating kinase 1 in tumor necrosis factor-alpha signal transduction. J Biol Chem 1998;273:17477-17482.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 17477-17482
-
-
Gotoh, Y.1
Cooper, J.A.2
-
5
-
-
49349083531
-
Redox control of cell fate by MAP kinase: Physiological roles of ASK1-MAP kinase pathway in stress signaling
-
Matsuzawa A, Ichijo H: Redox control of cell fate by MAP kinase: Physiological roles of ASK1-MAP kinase pathway in stress signaling. Biochim Biophys Acta 2008;1780:1325-1336.
-
(2008)
Biochim Biophys Acta.
, vol.1780
, pp. 1325-1336
-
-
Matsuzawa, A.1
Ichijo, H.2
-
6
-
-
33645156429
-
From acute ER stress to physiological roles of the unfolded protein response
-
Wu J, Kaufman RJ: From acute ER stress to physiological roles of the unfolded protein response. Cell Death Differ 2006;13:374-384.
-
(2006)
Cell Death Differ.
, vol.13
, pp. 374-384
-
-
Wu, J.1
Kaufman, R.J.2
-
7
-
-
33748789479
-
Mediators of endoplasmic reticulum stress-induced apoptosis
-
Szegezdi E, Logue SE, Gorman AM, Samali A: Mediators of endoplasmic reticulum stress-induced apoptosis. EMBO Rep 2006;7:880-885.
-
(2006)
EMBO Rep.
, vol.7
, pp. 880-885
-
-
Szegezdi, E.1
Logue, S.E.2
Gorman, A.M.3
Samali, A.4
-
8
-
-
31444449462
-
Role of the unfolded protein response in cell death
-
Kim R, Emi M, Tanabe K, Murakami S: Role of the unfolded protein response in cell death. Apoptosis 2006;11:5-13.
-
(2006)
Apoptosis
, vol.11
, pp. 5-13
-
-
Kim, R.1
Emi, M.2
Tanabe, K.3
Murakami, S.4
-
9
-
-
70449529426
-
Paraquat activates the IRE1/ASK1/JNK cascade associated with apoptosis in human neuroblastoma SH-SY5- cells
-
Yang W, Tiffany-Castiglioni E, Koh HC, Son IH: Paraquat activates the IRE1/ASK1/JNK cascade associated with apoptosis in human neuroblastoma SH-SY5- cells. Toxicol Lett 2009;191: 203-210.
-
(2009)
Toxicol. Lett.
, vol.191
, pp. 203-210
-
-
Yang, W.1
Tiffany-Castiglioni, E.2
Koh, H.C.3
Son, I.H.4
-
10
-
-
33646190885
-
The ASK1-MAP kinase signaling in ER stress and neurodegenerative diseases
-
Sekine Y, Takeda K, Ichijo H: The ASK1-MAP kinase signaling in ER stress and neurodegenerative diseases. Curr Mol Med 2006;6:87-97.
-
(2006)
Curr. Mol. Med.
, vol.6
, pp. 87-97
-
-
Sekine, Y.1
Takeda, K.2
Ichijo, H.3
-
11
-
-
2442432416
-
Involvement of caspase-4 in endoplasmic reticulum stress-induced apoptosis and Abeta-induced cell death
-
Hitomi J, Katayama T, Eguchi Y, Kudo T, Taniguchi M, Koyama Y, Manabe T, Yamagishi S, Bando Y, Imaizumi K, Tsujimoto Y, Tohyama M: Involvement of caspase-4 in endoplasmic reticulum stress-induced apoptosis and Abeta-induced cell death. J Cell Biol 2004;165:347-356.
-
(2004)
J. Cell Biol.
, vol.165
, pp. 347-356
-
-
Hitomi, J.1
Katayama, T.2
Eguchi, Y.3
Kudo, T.4
Taniguchi, M.5
Koyama, Y.6
Manabe, T.7
Yamagishi, S.8
Bando, Y.9
Imaizumi, K.10
Tsujimoto, Y.11
Tohyama, M.12
-
12
-
-
33846548110
-
ER stress and diseases
-
Yoshida H: ER stress and diseases. FEBS J 2007;274:630-658.
-
(2007)
FEBS J.
, vol.274
, pp. 630-658
-
-
Yoshida, H.1
-
13
-
-
71749110928
-
Targeting the endoplasmic reticulum-stress response as an anticancer strategy
-
Healy SJ, Gorman AM, Mousavi-Shafaei P, Gupta S, Samali A: Targeting the endoplasmic reticulum-stress response as an anticancer strategy. Eur J Pharmacol 2009;625:234-246.
-
(2009)
Eur. J. Pharmacol.
, vol.625
, pp. 234-246
-
-
Healy, S.J.1
Gorman, A.M.2
Mousavi-Shafaei, P.3
Gupta, S.4
Samali, A.5
-
14
-
-
0029013749
-
Studies on antiinflammatory effect of Japanese Oriental medicines (kampo medicines) used to treat inflammatory diseases
-
Ozaki Y: Studies on antiinflammatory effect of Japanese Oriental medicines (kampo medicines) used to treat inflammatory diseases. Biol Pharm Bull 1995;18:559-562.
-
(1995)
Biol. Pharm. Bull.
, vol.18
, pp. 559-562
-
-
Ozaki, Y.1
-
15
-
-
39149121841
-
Platycodin D induces apoptosis and decreases telomerase activity in human leukemia cells
-
Kim MO, Moon DO, Choi YH, Shin DY, Kang HS, Choi BT, Lee JD, Li W, Kim GY: Platycodin D induces apoptosis and decreases telomerase activity in human leukemia cells. Cancer Lett 2008;261:98-107.
-
(2008)
Cancer Lett.
, vol.261
, pp. 98-107
-
-
Kim, M.O.1
Moon, D.O.2
Choi, Y.H.3
Shin, D.Y.4
Kang, H.S.5
Choi, B.T.6
Lee, J.D.7
Li, W.8
Kim, G.Y.9
-
16
-
-
43049141875
-
Platycodin D induces mitotic arrest in vitro, leading to endoreduplication, inhibition of proliferation and apoptosis in leukemia cells
-
Kim MO, Moon DO, Choi YH, Lee JD, Kim ND, Kim GY: Platycodin D induces mitotic arrest in vitro, leading to endoreduplication, inhibition of proliferation and apoptosis in leukemia cells. Int J Cancer 2008;122:2674-2681.
-
(2008)
Int. J. Cancer
, vol.122
, pp. 2674-2681
-
-
Kim, M.O.1
Moon, D.O.2
Choi, Y.H.3
Lee, J.D.4
Kim, N.D.5
Kim, G.Y.6
-
17
-
-
33646153996
-
Platycodin Dinduced apoptosis through nuclear factor-kappaB activation in immortalized keratinocytes
-
Ahn KS, Hahn BS, Kwack K, Lee EB, Kim YS: Platycodin Dinduced apoptosis through nuclear factor-kappaB activation in immortalized keratinocytes. Eur J Pharmacol 2006;537:1-11.
-
(2006)
Eur. J. Pharmacol.
, vol.537
, pp. 1-11
-
-
Ahn, K.S.1
Hahn, B.S.2
Kwack, K.3
Lee, E.B.4
Kim, Y.S.5
-
18
-
-
77957363800
-
Platycodin D induces apoptosis in MCF-7 human breast cancer cells
-
Yu JS, Kim AK: Platycodin D induces apoptosis in MCF-7 human breast cancer cells. J Med Food 2010;13:298-305.
-
(2010)
J. Med. Food
, vol.13
, pp. 298-305
-
-
Yu, J.S.1
Kim, A.K.2
-
21
-
-
34547655717
-
Thioredoxin and thioredoxin-binding protein-2 in cancer and metabolic syndrome
-
Kaimul AM, Nakamura H, Masutani H, Yodoi J: Thioredoxin and thioredoxin-binding protein-2 in cancer and metabolic syndrome. Free Radic Biol Med 2007;43:861-868.
-
(2007)
Free Radic Biol. Med.
, vol.43
, pp. 861-868
-
-
Kaimul, A.M.1
Nakamura, H.2
Masutani, H.3
Yodoi, J.4
-
22
-
-
33746430147
-
Thioredoxin reductase as a novel molecular target for cancer therapy
-
Nguyen P, Awwad RT, Smart DD, Spitz DR, Gius D: Thioredoxin reductase as a novel molecular target for cancer therapy. Cancer Lett 2006;236:164-174.
-
(2006)
Cancer Lett.
, vol.236
, pp. 164-174
-
-
Nguyen, P.1
Awwad, R.T.2
Smart, D.D.3
Spitz, D.R.4
Gius, D.5
-
23
-
-
0033796101
-
The role of the redox protein thioredoxin in cell growth and cancer
-
Powis G, Mustacich D, Coon A: The role of the redox protein thioredoxin in cell growth and cancer. Free Radic Biol Med 2000;29:312-322.
-
(2000)
Free Radic Biol. Med.
, vol.29
, pp. 312-322
-
-
Powis, G.1
Mustacich, D.2
Coon, A.3
-
24
-
-
34547641948
-
Isoobtusilactone A induces cell cycle arrest and apoptosis through reactive oxygen species/apoptosis signal-regulating kinase 1 signaling pathway in human breast cancer cells
-
Kuo PL, Chen CY, Hsu YL: Isoobtusilactone A induces cell cycle arrest and apoptosis through reactive oxygen species/apoptosis signal-regulating kinase 1 signaling pathway in human breast cancer cells. Cancer Res 2007;67:7406-7420.
-
(2007)
Cancer Res.
, vol.67
, pp. 7406-7420
-
-
Kuo, P.L.1
Chen, C.Y.2
Hsu, Y.L.3
-
25
-
-
0036019933
-
Physiological roles of ASK1-mediated signal transduction in oxidative stress- and endoplasmic reticulum stress-induced apoptosis: Advanced findings from ASK1 knockout mice
-
Matsuzawa A, Nishitoh H, Tobiume K, Takeda K, Ichijo H: Physiological roles of ASK1-mediated signal transduction in oxidative stress- and endoplasmic reticulum stress-induced apoptosis: Advanced findings from ASK1 knockout mice. Antioxid Redox Signal 2002;4:415-425.
-
(2002)
Antioxid Redox Signal
, vol.4
, pp. 415-425
-
-
Matsuzawa, A.1
Nishitoh, H.2
Tobiume, K.3
Takeda, K.4
Ichijo, H.5
-
26
-
-
79951857650
-
Unfolded protein response in cancer: The physician's perspective
-
Li X, Zhang K, Li Z: Unfolded protein response in cancer: The physician's perspective. J Hematol Oncol 2011;4:8.
-
(2011)
J. Hematol. Oncol.
, vol.4
, pp. 8
-
-
Li, X.1
Zhang, K.2
Li, Z.3
-
27
-
-
1842843860
-
Coupling endoplasmic reticulum stress to the cell death program
-
Rao RV, Ellerby HM, Bredesen DE: Coupling endoplasmic reticulum stress to the cell death program. Cell Death Differ 2004;11:372-380.
-
(2004)
Cell Death Differ
, vol.11
, pp. 372-380
-
-
Rao, R.V.1
Ellerby, H.M.2
Bredesen, D.E.3
-
28
-
-
1842843855
-
Roles of CHOP/GADD153 in endoplasmic reticulum stress
-
Oyadomari S, Mori M: Roles of CHOP/GADD153 in endoplasmic reticulum stress. Cell Death Differ 2004;11:381-389.
-
(2004)
Cell Death Differ.
, vol.11
, pp. 381-389
-
-
Oyadomari, S.1
Mori, M.2
-
30
-
-
77952543940
-
Oxidative and endoplasmic reticulum stress signaling are involved in dehydrocostuslactone-mediated apoptosis in human non-small cell lung cancer cells
-
Hung JY, Hsu YL, Ni WC, Tsai YM, Yang CJ, Kuo PL, Huang MS: Oxidative and endoplasmic reticulum stress signaling are involved in dehydrocostuslactone- mediated apoptosis in human non-small cell lung cancer cells. Lung Cancer. 2010;68:355-365.
-
(2010)
Lung Cancer.
, vol.68
, pp. 355-365
-
-
Hung, J.Y.1
Hsu, Y.L.2
Ni, W.C.3
Tsai, Y.M.4
Yang, C.J.5
Kuo, P.L.6
Huang, M.S.7
-
31
-
-
29244462498
-
Coordination of ER and oxidative stress signaling: The PERK/Nrf2 signaling pathway
-
Cullinan SB, Diehl JA: Coordination of ER and oxidative stress signaling: The PERK/Nrf2 signaling pathway. Int J Biochem Cell Biol 2006;38:317-332.
-
(2006)
Int. J. Biochem. Cell Biol.
, vol.38
, pp. 317-332
-
-
Cullinan, S.B.1
Diehl, J.A.2
-
32
-
-
65549126847
-
PLAB induction in fenretinide-induced apoptosis of ovarian cancer cells occurs via a ROS-dependent mechanism involving ER stress and JNK activation
-
Appierto V, Tiberio P, Villani MG, Cavadini E, Formelli F: PLAB induction in fenretinide-induced apoptosis of ovarian cancer cells occurs via a ROS-dependent mechanism involving ER stress and JNK activation. Carcinogenesis 2009;30:824-831.
-
(2009)
Carcinogenesis
, vol.30
, pp. 824-831
-
-
Appierto, V.1
Tiberio, P.2
Villani, M.G.3
Cavadini, E.4
Formelli, F.5
-
33
-
-
58149352993
-
Thioredoxin system inhibitors as mediators of apoptosis for cancer therapy
-
Tonissen KF, Di Trapani G: Thioredoxin system inhibitors as mediators of apoptosis for cancer therapy. Mol Nutr Food Res 2009;53:87-103.
-
(2009)
Mol. Nutr. Food. Res.
, vol.53
, pp. 87-103
-
-
Tonissen, K.F.1
Di Trapani, G.2
-
34
-
-
28544450990
-
High thioredoxin expression is associated with resistance to docetaxel in primary breast cancer
-
Kim SJ, Miyoshi Y, Taguchi T, Tamaki Y, Nakamura H, Yodoi J, Kato K, Noguchi S: High thioredoxin expression is associated with resistance to docetaxel in primary breast cancer. Clin Cancer Res 2005;11:8425-8430.
-
(2005)
Clin. Cancer Res.
, vol.11
, pp. 8425-8430
-
-
Kim, S.J.1
Miyoshi, Y.2
Taguchi, T.3
Tamaki, Y.4
Nakamura, H.5
Yodoi, J.6
Kato, K.7
Noguchi, S.8
-
35
-
-
2342562556
-
Mitogen-activated protein kinases in apoptosis regulation
-
Wada T, Penninger JM: Mitogen-activated protein kinases in apoptosis regulation. Oncogene 2004;23:2838-2849.
-
(2004)
Oncogene
, vol.23
, pp. 2838-2849
-
-
Wada, T.1
Penninger, J.M.2
-
36
-
-
1642410790
-
Activation of apoptosis signalregulating kinase 1 by reactive oxygen species through dephosphorylation at serine 967 and 14-3-3 dissociation
-
Goldman EH, Chen L, Fu H: Activation of apoptosis signalregulating kinase 1 by reactive oxygen species through dephosphorylation at serine 967 and 14-3-3 dissociation. J Biol Chem 2004;279:10442-10449.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 10442-10449
-
-
Goldman, E.H.1
Chen, L.2
Fu, H.3
-
37
-
-
0035065836
-
ASK1 is required for sustained activations of JNK/p38 MAP kinases and apoptosis
-
Tobiume K, Matsuzawa A, Takahashi T, Nishitoh H, Morita K, Takeda K, Minowa O, Miyazono K, Noda T, Ichijo H: ASK1 is required for sustained activations of JNK/p38 MAP kinases and apoptosis. EMBO Rep 2001;2:222-228.
-
(2001)
EMBO Rep.
, vol.2
, pp. 222-228
-
-
Tobiume, K.1
Matsuzawa, A.2
Takahashi, T.3
Nishitoh, H.4
Morita, K.5
Takeda, K.6
Minowa, O.7
Miyazono, K.8
Noda, T.9
Ichijo, H.10
-
38
-
-
0036606540
-
ASK1 is essential for endoplasmic reticulum stress-induced neuronal cell death triggered by expanded polyglutamine repeats
-
Nishitoh H, Matsuzawa A, Tobiume K, Saegusa K, Takeda K, Inoue K, Hori S, Kakizuka A, Ichijo H: ASK1 is essential for endoplasmic reticulum stress-induced neuronal cell death triggered by expanded polyglutamine repeats. Genes Dev 2002;16: 1345-1355.
-
(2002)
Genes Dev.
, vol.16
, pp. 1345-1355
-
-
Nishitoh, H.1
Matsuzawa, A.2
Tobiume, K.3
Saegusa, K.4
Takeda, K.5
Inoue, K.6
Hori, S.7
Kakizuka, A.8
Ichijo, H.9
-
41
-
-
0035370949
-
Intracellular signaling from the endoplasmic reticulum to the nucleus: The unfolded protein response in yeast and mammals
-
Patil C, Walter P: Intracellular signaling from the endoplasmic reticulum to the nucleus: The unfolded protein response in yeast and mammals. Curr Opin Cell Biol 2001;13:349-355.
-
(2001)
Curr. Opin. Cell Biol.
, vol.13
, pp. 349-355
-
-
Patil, C.1
Walter, P.2
-
42
-
-
0346250162
-
Regulation of apoptosis by endoplasmic reticulum pathways
-
Breckenridge DG, Germain M, Mathai JP, Nguyen M, Shore GC: Regulation of apoptosis by endoplasmic reticulum pathways. Oncogene 2003;22:8608-8618.
-
(2003)
Oncogene
, vol.22
, pp. 8608-8618
-
-
Breckenridge, D.G.1
Germain, M.2
Mathai, J.P.3
Nguyen, M.4
Shore, G.C.5
-
43
-
-
54949135707
-
The endoplasmic reticulum in apoptosis and autophagy: Role of the BCL-2 protein family
-
Heath-Engel HM, Chang NC, Shore GC: The endoplasmic reticulum in apoptosis and autophagy: Role of the BCL-2 protein family. Oncogene 2008;27:6419-6433.
-
(2008)
Oncogene
, vol.27
, pp. 6419-6433
-
-
Heath-Engel, H.M.1
Chang, N.C.2
Shore, G.C.3
-
44
-
-
33645154135
-
Cellular response to endoplasmic reticulum stress: A matter of life or death
-
Boyce M, Yuan J: Cellular response to endoplasmic reticulum stress: A matter of life or death. Cell Death Differ 2006;13:363-373.
-
(2006)
Cell Death Differ.
, vol.13
, pp. 363-373
-
-
Boyce, M.1
Yuan, J.2
-
45
-
-
34548292913
-
Induction of endoplasmic reticulum stress by the pro-apoptotic retinoid N-(4-hydroxyphenyl) retinamide via a reactive oxygen species-dependent mechanism in human head and neck cancer cells
-
Kadara H, Lacroix L, Lotan D, Lotan R: Induction of endoplasmic reticulum stress by the pro-apoptotic retinoid N-(4-hydroxyphenyl) retinamide via a reactive oxygen species-dependent mechanism in human head and neck cancer cells. Cancer Biol Ther 2007;6:705-711.
-
(2007)
Cancer Biol. Ther.
, vol.6
, pp. 705-711
-
-
Kadara, H.1
Lacroix, L.2
Lotan, D.3
Lotan, R.4
|